Best TWAS P=1.26e-08 · Best GWAS P=7.28e-08 conditioned to 0.0161
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Liver | UHRF1BP1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 1.8e-02 | 4.3 | 5.3 | 1.5e-07 | 0.13 | 0.11 | 0.29 | TRUE |
2 | GTEx | Stomach | UHRF1BP1 | 0.24 | 0.22 | enet | 20 | 0.23 | 2.2e-11 | 3.6 | 5.2 | 1.5e-07 | 0.19 | 0.26 | 0.69 | FALSE |
3 | ROSMAP | Brain Pre-frontal Cortex | TEAD3 | 0.07 | 0.03 | bslmm | 421 | 0.04 | 5.6e-06 | 4.0 | -5.7 | 1.3e-08 | -0.45 | 0.14 | 0.80 | TRUE |