Best TWAS P=2.32e-10 · Best GWAS P=1.47e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | FRS3 | 0.15 | 0.04 | enet | 22 | 0.04 | 5.9e-04 | 6.8 | 5.7 | 1.1e-08 | 0.82 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Thyroid | FRS3 | 0.20 | 0.16 | lasso | 4 | 0.16 | 5.2e-12 | 6.8 | 6.3 | 2.3e-10 | 0.96 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | PRICKLE4 | 0.04 | 0.03 | lasso | 3 | 0.04 | 1.1e-04 | 6.0 | -5.1 | 3.0e-07 | -0.79 | 0.07 | 0.86 | FALSE |