[Hub]/) : Traits : Comparative height size at age 10 : →

chr1:9,049,032-12,013,869

Best TWAS P=1.68e-13 · Best GWAS P=4.23e-13 conditioned to 1.16e-14

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EXOSC10	0.06	0.08	lasso	2	0.07	6.8e-09	7.1	7.1	1.0e-12	-0.07	0.03	0.97	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MTOR	0.13	0.15	lasso	4	0.15	5.6e-18	6.7	6.6	3.6e-11	-0.06	0.15	0.85	FALSE
3	GTEx	Adipose Subcutaneous	EXOSC10	0.17	0.00	lasso	3	0.00	1.8e-01	6.9	7.0	1.8e-12	-0.06	0.03	0.34	FALSE
4	GTEx	Adipose Visceral Omentum	RP4-635E18.7	0.19	0.08	lasso	6	0.05	9.0e-04	7.1	6.2	6.3e-10	-0.05	0.03	0.94	FALSE
5	GTEx	Brain Cerebellar Hemisphere	EXOSC10	0.23	0.10	lasso	3	0.12	6.4e-04	6.6	6.8	1.1e-11	-0.09	0.02	0.87	FALSE
6	GTEx	Brain Cerebellum	EXOSC10	0.33	0.16	lasso	6	0.18	3.8e-06	6.9	6.9	5.1e-12	-0.05	0.04	0.95	FALSE
7	GTEx	Brain Cerebellum	RP4-635E18.7	0.17	0.17	lasso	5	0.09	1.3e-03	6.9	6.8	1.1e-11	-0.06	0.04	0.90	FALSE
8	GTEx	Brain Cortex	RP4-635E18.7	0.17	0.05	lasso	4	0.07	6.4e-03	6.7	6.8	1.2e-11	-0.08	0.06	0.66	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	PGD	0.17	0.14	lasso	6	0.08	1.7e-03	4.8	5.2	2.2e-07	-0.08	0.23	0.41	FALSE
10	GTEx	Lung	EXOSC10	0.11	0.07	lasso	4	0.05	1.2e-04	6.9	6.6	3.5e-11	-0.05	0.06	0.94	FALSE
11	GTEx	Stomach	RP4-635E18.7	0.13	0.06	enet	25	0.03	8.8e-03	6.0	5.1	2.9e-07	-0.03	0.04	0.87	FALSE
12	GTEx	Thyroid	RP4-635E18.7	0.07	0.02	lasso	2	0.01	5.5e-02	6.9	6.5	6.1e-11	-0.04	0.04	0.77	FALSE
13	GTEx	Whole Blood	MTOR	0.16	0.06	enet	18	0.07	5.1e-07	6.3	5.5	3.9e-08	-0.03	0.45	0.55	FALSE
14	METSIM	Adipose	EXOSC10	0.05	0.06	lasso	1	0.05	3.5e-08	5.6	5.6	1.8e-08	-0.07	0.05	0.95	FALSE
15	METSIM	Adipose	MTOR	0.04	0.02	bslmm	434	0.02	1.5e-04	6.7	6.6	4.1e-11	-0.07	0.08	0.91	FALSE
16	NTR	Blood	KIF1B	0.11	0.08	enet	11	0.09	3.7e-28	6.3	5.3	9.2e-08	-0.04	0.00	1.00	TRUE
17	ROSMAP	Brain Pre-frontal Cortex	EXOSC10	0.06	0.06	lasso	2	0.06	4.9e-08	7.1	7.0	2.7e-12	-0.06	0.03	0.97	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	MTOR	0.07	0.05	bslmm	423	0.04	2.0e-06	6.7	7.4	1.7e-13	-0.06	0.18	0.82	TRUE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTOR	0.02	0.02	blup	54	0.02	5.4e-03	7.1	7.0	2.7e-12	-0.08	0.02	0.88	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTOR	0.03	0.01	blup	54	0.02	5.9e-03	7.1	6.5	6.1e-11	-0.06	0.03	0.72	FALSE
21	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MASP2	0.05	0.03	blup	30	0.04	6.0e-03	2.2	-6.1	1.3e-09	0.06	0.02	0.58	FALSE
22	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	H6PD	0.31	0.06	blup	64	0.14	3.8e-06	4.4	-5.8	5.5e-09	-0.04	0.02	0.76	TRUE