TWAS hub - PGD

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.1549	0.0770	3.6e-03	0.095	NA	0.005	NA	0.025	2.7e-04	NA	2.0e-01	NA	4.3e-02
2	GTEx	Artery Tibial	0.0686	0.0426	9.3e-03	0.002	NA	0.001	NA	-0.003	2.2e-01	NA	2.6e-01	NA	6.7e-01
3	GTEx	Cells EBV-transformed lymphocytes	0.1710	0.0690	7.3e-04	0.137	NA	0.052	NA	0.077	3.1e-05	NA	8.6e-03	NA	1.7e-03
4	GTEx	Cells Transformed fibroblasts	0.4660	0.0520	0.0e+00	0.563	NA	0.551	NA	0.522	1.6e-50	NA	7.5e-49	NA	2.8e-45
5	GTEx	Esophagus Muscularis	0.0680	0.0300	6.8e-04	0.053	NA	0.051	NA	-0.004	3.8e-04	NA	4.8e-04	NA	7.6e-01
6	GTEx	Muscle Skeletal	0.1398	0.0364	7.2e-12	0.152	NA	0.159	NA	0.085	9.6e-15	NA	2.1e-15	NA	1.0e-08
7	GTEx	Skin Sun Exposed Lower leg	0.0850	0.0370	2.5e-04	0.059	NA	0.049	NA	0.059	1.2e-05	NA	6.4e-05	NA	1.3e-05
8	GTEx	Stomach	0.1020	0.0440	8.5e-04	-0.006	NA	-0.002	NA	-0.003	8.5e-01	NA	3.9e-01	NA	4.8e-01
9	TCGA	Bladder Urothelial Carcinoma	0.0360	0.0260	4.6e-03	0.018	0.026	0.021	NA	0.020	1.0e-02	2.6e-03	5.8e-03	NA	7.1e-03
10	TCGA	Breast Invasive Carcinoma	0.0580	0.0226	1.8e-13	0.066	0.072	0.072	NA	0.073	2.2e-13	1.9e-14	1.3e-14	NA	9.8e-15
11	TCGA	Cervical Squamous Cell Carcinoma	0.1860	0.0930	1.2e-03	0.055	0.024	0.045	NA	0.023	1.1e-03	2.4e-02	2.9e-03	NA	2.5e-02
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0373	0.0237	3.3e-03	0.031	0.010	0.013	NA	0.020	1.7e-04	2.4e-02	1.1e-02	NA	2.1e-03
13	TCGA	Lung Adenocarcinoma	0.0423	0.0216	8.7e-06	0.060	0.048	0.048	NA	0.056	1.3e-07	2.7e-06	2.3e-06	NA	3.9e-07
14	TCGA	Lung Squamous Cell Carcinoma	0.0280	0.0197	6.2e-03	0.027	0.011	0.005	NA	0.012	4.3e-04	2.0e-02	7.1e-02	NA	1.4e-02
15	TCGA	Ovarian Serous Cystadenocarcinoma	0.0600	0.0390	3.2e-03	-0.003	-0.002	0.014	NA	0.007	6.3e-01	4.7e-01	3.8e-02	NA	9.8e-02
16	TCGA	Pancreatic Adenocarcinoma	0.0680	0.0470	5.8e-03	-0.002	0.015	0.038	NA	0.009	4.2e-01	7.3e-02	1.0e-02	NA	1.3e-01
17	TCGA	Pheochromocytoma and Paraganglioma	0.0910	0.0570	8.5e-03	0.021	0.047	0.029	NA	0.024	4.8e-02	6.0e-03	2.6e-02	NA	3.7e-02
18	TCGA	Stomach Adenocarcinoma	0.0490	0.0310	5.3e-03	0.044	0.030	0.023	NA	0.028	3.6e-04	2.8e-03	8.6e-03	NA	4.1e-03
19	TCGA	Thyroid Carcinoma	0.0560	0.0290	1.0e-04	0.053	0.022	0.029	NA	0.016	7.0e-06	3.2e-03	7.7e-04	NA	1.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Multivitamins +/- minerals	20.2	25.6	33.6	-5.6	-3.3	-5.3	-5.7	-5.6	-5.7	-4.6	-5.7	-5.4	-5.6	-3.7	-4.5	-5.8	-3.1	-5.1	-4.5	-4.5	-5.4	-5.6
Vitamin and mineral supplements	11.7	15.9	20.0	4.4	2.9	4.2	4.5	4.2	4.5	3.1	4.5	4.3	4.3	2.9	4.1	4.5	2.8	3.9	4.0	3.6	4.1	4.3
Maternal smoking around birth	5.3	7.6	10.8	3.1	2.7	3.2	3.1	2.8	3.0	2.7	3.0	3.3	3.0	1.4	2.2	3.0	1.5	2.8	2.3	2.7	2.9	3.0
Tinnitus: Yes, but not now, but have in the past	4.9	5.2	7.6	-2.6	-2.1	-2.4	-2.6	-2.7	-2.6	-1.1	-2.8	-2.6	-2.6	-2.1	-1.9	-2.6	-1.2	-2.7	-1.1	-1.7	-2.5	-2.5
Forced expiratory volume in 1-second (FEV1), predicted	4.9	10.2	18.8	3.3	3.3	4.3	3.4	2.8	3.4	3.7	3.1	3.1	3.0	0.3	2.8	3.4	2.9	2.3	3.8	3.6	2.8	3.6
Mouth/teeth dental problems: Loose teeth	4.5	5.4	9.6	2.5	1.0	1.7	2.5	3.1	2.5	2.8	2.7	2.4	2.8	2.0	1.2	2.5	1.7	3.0	1.8	2.0	2.4	2.3
Serious illness, injury or assault to yourself	4.3	5.3	8.2	-2.8	-1.3	-2.3	-2.6	-2.4	-2.6	-2.2	-2.5	-2.3	-2.6	-1.8	-2.9	-2.7	-0.6	-2.2	-1.6	-1.6	-2.8	-2.5
Lung FEV1/FVC ratio	4.0	20.4	33.9	-5.0	-4.4	-4.9	-5.1	-4.4	-5.1	-3.6	-4.9	-5.8	-4.6	-0.8	-4.4	-5.1	-3.1	-4.2	-3.6	-5.1	-4.4	-4.9
Number of treatments/medications taken	3.7	6.6	11.1	-2.5	-2.2	-2.3	-2.5	-2.9	-2.6	-3.0	-2.8	-2.5	-2.8	-0.5	-2.9	-2.5	-1.9	-3.0	-3.3	-2.5	-2.1	-2.6
Falls in the last year	3.7	5.0	7.2	-2.6	-1.8	-2.7	-2.5	-2.1	-2.5	-2.3	-2.3	-2.5	-2.4	0.1	-2.3	-2.6	-1.8	-1.9	-1.7	-2.6	-2.3	-2.4
Medication: Paracetamol	3.7	6.2	8.0	-2.8	-2.4	-2.5	-2.7	-2.6	-2.7	-2.6	-2.8	-2.5	-2.8	-0.8	-2.4	-2.7	-1.1	-2.8	-2.4	-2.3	-2.6	-2.6
Height	3.5	66.8	127.7	9.1	5.9	11.3	9.3	6.2	9.2	9.9	7.8	8.6	7.6	1.9	7.9	9.2	6.3	4.6	8.0	9.7	8.4	9.2
Medication for pain relief, constipation, heartburn	3.5	6.0	8.8	2.7	1.9	2.4	2.6	2.6	2.6	2.2	2.7	2.5	2.8	1.5	2.1	2.7	1.7	3.0	2.1	2.4	2.6	2.6
Long-standing illness, disability or infirmity	3.5	5.4	10.0	-2.6	-2.5	-1.5	-2.5	-3.2	-2.5	-2.5	-2.7	-2.0	-3.0	-1.1	-1.9	-2.6	-0.4	-2.8	-1.6	-1.5	-2.4	-2.6
Hair/balding pattern: Pattern 2	3.3	4.2	7.0	-2.3	-1.7	-2.6	-2.3	-1.5	-2.3	-1.4	-2.0	-2.4	-2.0	-1.1	-2.3	-2.3	-1.6	-1.6	-2.3	-2.5	-1.7	-2.2
Medication: Metformin	3.2	4.5	8.1	-2.2	-2.4	-2.2	-2.2	-2.3	-2.2	-2.8	-2.2	-2.1	-2.2	0.1	-1.4	-2.3	-1.9	-1.8	-2.5	-2.3	-1.6	-2.3
Standing height	3.1	30.5	64.5	6.2	3.6	8.0	6.3	3.6	6.2	7.5	5.0	5.2	4.9	1.6	5.0	6.1	4.7	2.4	5.5	6.5	5.8	6.4
Migraine (self-reported)	3.1	3.8	6.2	-2.1	-1.7	-1.6	-2.2	-2.5	-2.2	-1.3	-2.5	-2.1	-2.2	-2.2	-1.7	-2.2	-0.5	-2.3	-1.0	-1.2	-2.2	-2.1
Shortness of breath walking on level ground	3.0	3.6	5.3	-2.0	-2.2	-1.7	-1.9	-2.3	-1.9	-2.3	-2.0	-1.9	-2.1	0.3	-1.7	-2.0	-1.3	-1.9	-1.7	-2.0	-1.6	-1.9
Severe depression (siblings)	2.9	3.2	6.6	-1.7	-2.1	-1.3	-1.7	-1.7	-1.7	-1.3	-1.9	-2.5	-1.8	-1.1	-2.6	-1.7	-0.9	-2.2	-2.2	-1.8	-1.5	-1.5
Sensitivity / hurt feelings	2.7	4.7	8.4	-2.2	-1.9	-1.6	-2.3	-2.3	-2.2	-1.4	-2.5	-2.9	-2.3	-0.8	-2.7	-2.2	-1.2	-2.9	-2.3	-2.3	-2.0	-2.0
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.4	6.0	-2.4	-2.1	-1.8	-2.3	-2.3	-2.3	-1.6	-2.2	-2.5	-2.4	-1.2	-2.4	-2.3	-1.0	-2.0	-2.1	-2.1	-2.1	-2.2
Lung cancer (father)	2.7	3.2	5.6	-1.9	-1.6	-1.7	-1.8	-2.2	-1.8	-1.9	-2.1	-1.8	-2.1	-1.1	-0.7	-1.8	-1.3	-2.4	-1.4	-1.7	-1.7	-1.9
Medication: Blood pressure	2.7	4.7	9.3	-2.3	-1.9	-2.0	-2.3	-2.4	-2.4	-3.1	-2.2	-1.2	-2.4	-1.5	-2.6	-2.3	-0.7	-1.8	-2.9	-1.5	-2.3	-2.4
Medication: Paracetamol	2.7	4.2	5.9	-2.1	-1.9	-2.1	-2.1	-2.1	-2.1	-2.0	-2.2	-2.1	-2.2	-0.2	-2.2	-2.1	-1.5	-2.2	-2.4	-2.2	-2.0	-2.2
Cardiovascular Disease	2.6	8.4	19.2	-3.0	-3.1	-3.7	-3.0	-2.5	-3.1	-4.4	-2.7	-2.0	-2.9	-1.3	-2.5	-3.0	-2.9	-1.9	-3.5	-2.8	-2.5	-3.2
Diabetes (self-reported)	2.6	4.1	6.7	-2.2	-1.9	-2.0	-2.2	-2.3	-2.2	-2.6	-2.1	-1.9	-2.3	-0.0	-2.1	-2.2	-0.8	-1.9	-2.1	-1.7	-1.9	-2.3
Medication for cholesterol, blood pressure or diabetes	2.6	4.3	10.6	2.1	1.9	1.6	2.1	2.4	2.2	3.2	2.1	1.3	2.2	1.3	2.5	2.1	0.9	1.8	2.9	1.4	1.9	2.2
Diabetes diagnosed by doctor	2.6	4.2	7.3	-2.3	-1.6	-1.5	-2.2	-2.6	-2.2	-2.7	-2.3	-2.1	-2.5	-0.2	-1.8	-2.2	-1.1	-2.3	-2.0	-1.7	-1.8	-2.3
Mouth/teeth dental problems: Mouth ulcers	2.6	4.2	6.6	-2.2	-2.3	-2.1	-2.1	-2.1	-2.1	-1.3	-2.1	-1.9	-2.1	-1.2	-2.1	-2.3	-1.8	-1.9	-2.6	-2.0	-1.9	-2.1
Type 2 Diabetes (T2D) (2018)	2.4	4.5	6.4	-2.5	-1.5	-2.0	-2.4	-2.5	-2.4	-2.3	-2.3	-2.2	-2.5	-0.5	-2.2	-2.4	-0.9	-2.0	-2.0	-1.9	-1.9	-2.4
Systolic blood pressure, automated reading	2.4	7.0	10.2	2.9	2.2	2.4	2.9	3.2	2.9	1.4	3.0	3.2	3.0	1.3	2.3	2.9	1.8	3.0	2.4	2.8	2.7	3.0
Medication for hormone replacement therapy	2.4	2.6	4.6	-1.7	-2.1	-2.0	-1.7	-1.7	-1.7	-0.9	-1.7	-1.8	-1.7	0.9	-1.2	-1.7	-1.3	-1.6	-1.4	-2.1	-1.2	-1.7
Mouth/teeth dental problems: Dentures	2.4	4.0	8.3	2.1	1.1	1.0	2.0	2.9	2.0	1.5	2.4	1.7	2.5	2.5	1.2	2.1	1.4	2.7	2.0	1.2	2.2	2.0
Breast cancer (self-reported)	2.4	2.8	6.6	-1.4	-2.4	-0.8	-1.6	-1.8	-1.6	-1.3	-1.7	-1.5	-1.6	-0.8	-1.6	-1.5	-2.6	-1.5	-2.6	-1.7	-1.0	-1.7
Medication: Aspirin	2.4	3.1	6.7	-1.5	-2.0	-1.6	-1.6	-1.7	-1.6	-2.4	-1.7	-1.6	-1.6	-0.9	-2.3	-1.5	-1.8	-1.7	-2.6	-1.6	-1.3	-1.7
Supplements: Fish oil (including cod liver oil)	2.4	3.2	6.7	-1.9	-2.0	-1.8	-1.9	-2.1	-1.9	0.0	-2.1	-2.6	-2.0	-0.6	-1.1	-1.9	-1.7	-2.2	-1.2	-2.0	-1.3	-1.8
Exposure to tobacco smoke at home	2.3	2.6	5.2	1.7	1.1	0.7	1.7	2.2	1.7	0.7	1.9	1.7	2.0	2.3	1.0	1.7	1.1	2.2	1.2	1.0	1.6	1.7
Comparative height size at age 10	2.3	12.7	26.8	4.3	1.5	5.2	4.3	2.4	4.2	4.9	3.4	3.5	3.4	2.4	3.2	4.2	1.1	2.0	2.3	3.4	4.6	4.0
Suffer from ‘nerves’	2.3	3.7	7.5	-2.0	-2.7	-1.9	-2.0	-1.8	-1.9	-2.3	-1.7	-1.9	-1.9	-0.2	-1.9	-2.0	-1.6	-1.4	-2.1	-2.1	-1.8	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.4	3.8	-1.8	-1.4	-1.2	-1.8	-1.9	-1.7	-1.4	-1.8	-1.9	-1.9	-0.5	-1.5	-1.7	-0.2	-1.8	-1.3	-1.4	-1.5	-1.5
Number of self-reported non-cancer illnesses	2.3	4.0	8.6	-1.9	-2.8	-1.2	-1.8	-2.9	-1.9	-2.4	-2.3	-1.7	-2.4	-0.6	-1.5	-1.8	-1.7	-2.6	-2.3	-1.4	-1.3	-2.0
Hearing difficulty/problems: Yes	2.2	3.4	7.7	2.1	0.7	1.6	2.0	2.0	2.0	0.7	2.2	2.5	2.2	2.0	1.6	1.9	0.1	2.8	1.5	1.6	2.0	1.8
Age when periods started (menarche)	2.2	5.3	8.3	2.7	1.8	2.9	2.7	2.4	2.7	2.5	2.5	1.7	2.5	1.5	1.2	2.7	1.9	1.6	1.4	2.1	2.8	2.8
Medication: Simvastatin	2.2	3.2	10.0	-1.6	-1.6	-1.5	-1.6	-1.5	-1.7	-3.2	-1.6	-1.8	-1.6	-0.3	-2.3	-1.6	-1.4	-1.5	-2.6	-2.0	-1.2	-1.6
Supplements: Vitamin C	2.2	2.6	5.3	-1.5	-1.5	-1.4	-1.5	-1.7	-1.5	-0.6	-1.7	-2.0	-1.7	-0.4	-1.3	-1.6	-2.3	-2.0	-2.2	-2.1	-0.9	-1.4
Breast Cancer	2.0	4.7	20.0	1.8	3.1	2.0	1.8	1.9	1.9	2.3	1.8	1.6	1.8	0.9	0.8	1.9	4.5	0.6	3.4	2.2	1.1	2.4
Ovarian Cancer	2.0	2.7	4.1	1.9	1.3	2.0	2.0	1.4	1.9	1.0	1.7	1.7	1.7	1.5	1.3	2.0	1.3	1.2	0.9	1.7	2.0	2.0
HbA1C	2.0	2.2	5.8	1.4	1.8	1.8	1.5	0.8	1.4	2.4	1.1	1.7	1.2	1.1	1.3	1.8	0.0	1.2	1.4	1.6	1.6	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.3	5.2	-1.8	-1.5	-1.6	-1.8	-1.3	-1.7	-2.2	-1.6	-0.9	-1.5	-1.4	-1.4	-1.7	-0.1	-1.1	-1.1	-1.0	-2.3	-1.7
Cholesterol lowering medication	2.0	3.0	6.7	-1.7	-1.8	-1.5	-1.7	-1.7	-1.7	-2.6	-1.7	-1.8	-1.8	-0.4	-2.1	-1.6	-1.2	-1.7	-2.0	-1.7	-1.6	-1.6
Supplements: Zinc	1.9	2.1	4.6	-1.6	-1.6	-1.6	-1.6	-1.1	-1.6	-0.3	-1.3	-1.7	-1.4	0.2	-1.1	-1.7	-2.2	-0.8	-1.1	-2.1	-1.4	-1.7
Forced vital capacity (FVC), Best measure	1.9	7.0	19.4	2.7	2.0	2.9	2.7	2.6	2.8	4.4	2.5	1.9	2.6	0.0	1.6	2.6	3.2	1.8	3.1	3.1	2.0	2.9
Ever had bowel cancer screening	1.9	2.2	4.8	-1.2	-1.6	-1.0	-1.4	-1.7	-1.4	-1.0	-1.6	-1.9	-1.3	-0.5	-1.8	-1.3	-1.5	-1.7	-2.2	-1.7	-0.9	-1.3
Illnesses of father: None of the above (group 1)	1.9	2.3	4.8	1.5	1.5	1.6	1.5	1.3	1.6	1.4	1.5	1.7	1.5	0.3	1.7	1.5	1.4	1.7	2.2	1.9	0.9	1.4
Happiness	1.8	2.2	6.3	1.1	2.0	1.7	1.2	0.9	1.3	1.1	1.2	1.5	1.0	0.5	1.3	1.1	2.5	1.0	2.5	2.0	0.9	1.4
Trunk predicted mass	1.8	10.4	21.9	3.3	1.9	3.2	3.3	3.6	3.5	4.7	3.4	2.5	3.5	0.9	1.1	3.3	3.8	3.0	3.6	3.4	2.7	3.9
Gout (self-reported)	1.8	2.5	3.6	1.7	1.4	1.9	1.7	1.2	1.7	1.5	1.6	1.6	1.6	1.4	1.2	1.8	1.2	1.5	1.7	1.8	1.7	1.7
Exposure to tobacco smoke outside home	1.8	2.4	5.0	1.4	1.4	1.2	1.5	1.8	1.5	1.4	1.7	1.8	1.6	0.2	1.1	1.5	2.2	1.7	1.9	1.9	1.1	1.6
Guilty feelings	1.8	2.7	4.3	-1.9	-1.9	-0.9	-1.8	-2.1	-1.8	-1.0	-1.8	-1.7	-2.1	-1.0	-1.0	-1.9	-1.1	-2.0	-1.6	-1.5	-1.6	-1.7
Alcohol drinker status: Never	1.8	2.2	4.3	1.4	1.7	1.7	1.6	1.0	1.5	1.5	1.4	1.2	1.2	0.8	1.9	1.5	1.4	1.1	2.1	1.6	1.4	1.7
Pain experienced in last month	1.8	2.9	5.2	1.8	1.0	1.7	1.8	1.5	1.8	1.0	1.7	2.1	1.7	0.9	2.3	1.9	1.8	1.5	2.1	2.1	1.5	1.7
Blood Platelet Count	1.7	19.5	72.9	-4.3	-3.1	-8.5	-4.5	0.2	-4.4	-5.3	-2.8	-4.6	-2.0	-2.9	-6.3	-4.4	-3.8	0.7	-4.3	-5.0	-4.6	-4.5
Trunk fat-free mass	1.7	10.0	21.6	3.2	1.9	3.2	3.2	3.5	3.4	4.7	3.3	2.4	3.4	0.9	1.0	3.3	3.8	2.9	3.6	3.4	2.7	3.8
Medication: Allopurinol	1.7	2.3	5.0	1.8	1.7	2.2	1.8	0.8	1.8	1.1	1.4	1.4	1.4	1.5	1.6	1.8	0.5	0.8	1.2	1.2	2.0	1.8
Medication: Aspirin	1.7	2.2	4.5	-1.3	-1.4	-1.2	-1.4	-1.6	-1.4	-1.8	-1.6	-1.4	-1.4	-1.2	-2.1	-1.3	-1.4	-1.6	-2.1	-1.2	-1.2	-1.5
Whole body water mass	1.7	9.5	24.7	3.1	1.8	3.3	3.1	3.2	3.2	5.0	3.1	2.3	3.2	0.9	1.0	3.1	3.7	2.6	3.5	3.4	2.6	3.6
Relative age of first facial hair	1.6	3.3	6.5	-2.1	-1.4	-2.4	-2.1	-1.4	-2.0	-0.6	-1.9	-2.4	-1.7	-1.5	-2.5	-2.1	0.6	-1.7	-1.0	-1.4	-2.3	-1.6
Medication: Co-codamol	1.6	1.9	6.8	1.4	1.2	1.4	1.6	1.1	1.5	1.2	1.4	0.7	1.2	2.6	1.5	1.5	-0.4	0.7	0.6	0.1	2.3	1.5
Taking other prescription medications	1.6	2.5	6.3	-1.3	-1.8	-0.4	-1.4	-2.5	-1.4	-2.1	-1.9	-1.3	-1.9	-0.4	-1.6	-1.3	-0.5	-2.4	-2.1	-0.8	-1.0	-1.5
Forced vital capacity (FVC)	1.6	6.3	13.2	2.6	1.8	2.9	2.7	2.4	2.7	3.6	2.4	2.0	2.5	-0.3	1.3	2.6	3.3	1.6	2.9	3.1	1.9	2.9
Neuroticism score	1.6	3.3	5.8	-1.8	-2.2	-1.0	-1.8	-2.0	-1.8	-1.6	-1.9	-2.4	-2.0	-0.6	-2.4	-1.9	-0.9	-2.2	-1.9	-1.7	-1.8	-1.5
Alcohol intake frequency.	1.6	3.8	7.4	1.9	1.8	2.3	1.9	1.7	1.9	1.3	2.0	1.9	1.9	1.6	2.5	1.9	1.6	1.9	2.7	1.7	1.9	2.0
Whole body fat-free mass	1.6	9.4	25.2	3.1	1.9	3.2	3.1	3.1	3.2	5.0	3.1	2.2	3.2	0.8	1.0	3.1	3.7	2.6	3.5	3.3	2.6	3.6
Medication for cholesterol	1.6	2.4	5.4	1.5	2.3	1.6	1.4	1.5	1.5	2.0	1.4	1.5	1.6	-0.4	1.3	1.5	1.5	1.5	2.0	1.8	1.0	1.4
Mineral and other dietary supplements	1.6	2.1	5.2	1.4	1.3	1.2	1.5	2.0	1.5	-0.1	1.8	2.3	1.7	-0.1	0.7	1.4	1.4	2.2	0.8	1.7	0.8	1.3
Ever had hysterectomy (womb removed)	1.5	1.7	4.5	-1.0	-1.5	-1.1	-1.2	-1.6	-1.2	-0.7	-1.3	-1.7	-1.3	0.2	-1.4	-1.2	-1.2	-1.6	-2.1	-1.7	-0.5	-1.1
Relative age voice broke	1.5	2.3	3.7	-1.8	-1.9	-1.6	-1.8	-1.5	-1.8	-0.7	-1.6	-1.7	-1.7	-1.3	-1.6	-1.8	0.2	-1.3	-0.6	-1.0	-1.9	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.3	7.8	-1.8	-1.2	-0.6	-1.8	-2.5	-1.7	-2.6	-2.2	-1.7	-2.1	-0.9	-2.1	-1.7	-0.1	-2.8	-2.0	-1.1	-1.6	-1.7
Peak expiratory flow (PEF)	1.5	3.6	7.2	-2.1	-1.8	-2.3	-2.1	-1.4	-2.0	-0.4	-1.9	-2.7	-1.7	-1.3	-2.6	-2.1	-0.9	-1.5	-1.4	-2.0	-2.2	-1.8
Ever highly irritable/argumentative for 2 days	1.5	1.8	3.2	1.4	1.7	1.8	1.6	1.2	1.6	0.9	1.5	1.3	1.2	1.2	0.6	1.5	0.9	0.8	0.7	1.3	1.6	1.7
Emphysema/chronic bronchitis	1.5	1.7	3.6	-1.1	-0.8	-0.8	-1.0	-1.7	-1.0	-1.8	-1.2	-1.2	-1.6	1.2	-0.6	-1.1	-1.7	-1.9	-1.9	-1.4	-0.2	-1.0
Leg fat-free mass (right)	1.5	8.1	28.1	2.9	1.7	3.3	2.8	2.5	2.9	5.3	2.7	2.0	2.7	0.7	0.9	2.8	3.2	2.1	3.3	3.2	2.5	3.3
Leg predicted mass (right)	1.5	8.0	27.7	2.8	1.7	3.3	2.8	2.5	2.9	5.3	2.7	2.0	2.7	0.6	0.9	2.8	3.2	2.1	3.3	3.2	2.4	3.3
Body Mass Index (BMI) (2010)	1.4	1.9	4.4	-1.3	-1.3	-1.2	-1.5	-1.0	-1.4	-0.6	-1.3	-2.1	-1.2	0.1	-2.1	-1.4	0.0	-1.2	-1.7	-1.9	-1.2	-1.4
Neuroticism	1.4	3.4	7.1	-1.8	-2.1	-0.8	-1.7	-2.2	-1.7	-1.8	-2.0	-2.4	-2.1	-0.7	-2.2	-1.8	-1.0	-2.7	-1.9	-1.7	-1.7	-1.4
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	3.4	-1.6	-1.3	-0.9	-1.4	-1.8	-1.4	-1.9	-1.5	-0.7	-1.6	-0.8	-1.6	-1.4	0.9	-1.1	-0.4	-0.0	-1.7	-1.5
Number of operations (self-reported)	1.4	2.0	6.1	-1.3	-0.9	-0.5	-1.3	-2.4	-1.4	0.2	-1.8	-1.7	-1.8	-0.5	-0.5	-1.4	-1.1	-2.5	-1.7	-1.3	-0.9	-1.3
Average weekly beer plus cider intake	1.4	2.0	4.2	1.3	2.0	1.4	1.5	1.4	1.6	-0.2	1.6	1.5	1.4	1.2	1.3	1.4	1.6	1.3	1.3	1.3	1.4	1.7
Coronary Artery Disease (CAD)	1.3	1.5	3.3	1.1	0.9	0.9	1.2	1.4	1.2	1.0	1.3	1.7	1.2	0.6	1.5	1.1	0.0	1.6	1.8	1.4	0.9	1.2
Diabetes (father)	1.3	1.7	3.3	-1.2	-1.2	-1.2	-1.2	-1.4	-1.2	-1.1	-1.3	-1.8	-1.3	0.2	-0.6	-1.3	-1.8	-1.4	-1.6	-1.7	-0.3	-1.1
Leg fat-free mass (left)	1.3	7.1	25.4	2.7	1.4	3.2	2.7	2.3	2.8	5.0	2.5	1.8	2.6	0.9	0.7	2.6	3.0	1.9	2.9	2.9	2.4	3.1
Leg predicted mass (left)	1.3	7.1	24.8	2.7	1.5	3.2	2.7	2.3	2.8	5.0	2.5	1.8	2.6	0.9	0.8	2.7	3.0	1.9	3.0	2.9	2.4	3.1
Number of children fathered	1.3	1.4	3.7	-1.0	-1.7	-1.0	-1.1	-1.7	-1.2	-1.9	-1.3	-0.6	-1.2	-0.2	-0.6	-1.0	-1.0	-1.1	-1.4	-1.0	-0.9	-1.4
Knee pain experienced in last month	1.3	2.0	5.7	-1.3	-0.2	-1.5	-1.3	-0.9	-1.3	-1.0	-1.2	-1.9	-1.1	1.0	-2.4	-1.4	-1.3	-1.0	-1.9	-2.0	-1.0	-1.3
Ever depressed for a whole week	1.3	1.6	3.1	1.3	0.7	1.6	1.4	1.4	1.4	1.1	1.5	1.1	1.4	1.8	0.7	1.3	0.6	1.5	1.0	1.0	1.5	1.4
Myopia	1.3	1.9	3.0	-1.6	-0.8	-1.3	-1.6	-1.7	-1.6	-1.7	-1.7	-0.9	-1.6	-1.5	-0.6	-1.6	0.1	-1.4	-0.2	-0.4	-1.6	-1.7
Verbal and Numeric Reasoning (VNR)	1.2	3.0	6.6	1.7	2.6	1.7	1.7	1.5	1.7	1.6	1.7	2.1	1.7	-0.6	1.2	1.7	1.5	1.9	1.8	2.5	1.1	1.7
Lupus	1.2	1.9	2.8	1.6	1.5	1.4	1.6	1.5	1.6	1.0	1.6	1.3	1.6	0.9	0.6	1.5	0.5	1.7	1.0	1.5	1.5	1.5
Hand grip strength (right)	1.2	3.2	11.8	1.2	2.3	-0.4	1.1	3.4	1.3	3.0	2.0	0.0	2.3	0.2	-0.5	1.2	1.9	2.5	2.3	0.6	0.6	1.7
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.7	-1.2	-1.0	-0.8	-1.3	-1.6	-1.3	-0.7	-1.4	-1.5	-1.4	-0.0	-1.3	-1.2	-0.7	-1.6	-1.3	-1.3	-0.8	-1.1
High blood pressure (mother)	1.2	1.6	3.2	-1.4	-1.8	-1.4	-1.4	-1.4	-1.5	-1.4	-1.2	-1.0	-1.3	-1.2	-0.1	-1.4	-1.1	-0.7	-0.8	-1.3	-1.1	-1.4
Medication: Lansoprazole	1.2	1.3	2.4	-1.3	-0.5	-0.5	-1.1	-1.5	-1.2	-1.2	-1.3	-0.4	-1.5	-1.1	-0.6	-1.3	-1.0	-1.6	-1.5	-0.9	-1.0	-1.1
Eye problems/disorders: None of the above	1.2	1.3	2.9	1.2	0.7	1.1	1.3	1.0	1.3	0.7	1.1	1.1	1.1	1.1	1.7	1.2	0.8	0.7	1.7	1.2	1.3	1.2
Average weekly red wine intake	1.2	1.7	5.0	-1.0	-1.4	-2.0	-1.1	-0.4	-1.1	-0.3	-1.0	-1.5	-0.7	-0.9	-1.8	-1.2	-2.2	-0.6	-1.8	-1.8	-0.9	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	4.7	-1.8	-1.9	-1.5	-1.9	-1.6	-1.8	-0.9	-1.8	-1.8	-1.6	-1.7	-2.2	-1.8	0.5	-1.3	-0.7	-0.6	-2.1	-1.7
Medication: Bendroflumethiazide	1.2	1.9	5.2	-1.3	-1.7	-2.3	-1.4	-0.9	-1.4	-1.7	-1.2	-1.0	-1.2	-0.1	-1.5	-1.3	-1.1	-0.9	-1.4	-1.3	-1.3	-1.5
Basal metabolic rate	1.2	6.9	22.0	2.7	1.5	2.9	2.7	2.5	2.8	4.7	2.6	1.8	2.7	0.9	0.7	2.6	3.1	2.0	3.0	2.8	2.3	3.1
Fed-up feelings	1.1	2.0	4.1	-1.6	-1.6	-1.3	-1.5	-1.3	-1.4	-1.4	-1.4	-1.7	-1.4	-0.9	-2.0	-1.5	0.1	-1.4	-1.1	-1.0	-1.8	-1.2
Sitting height	1.1	7.6	17.4	3.0	1.5	3.7	3.0	2.1	3.0	4.2	2.5	2.4	2.5	0.5	2.2	2.9	2.8	1.1	3.2	3.3	2.6	3.2
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.7	-1.4	0.0	-1.3	-1.4	-1.1	-1.4	-0.5	-1.4	-1.1	-1.4	-0.6	-0.9	-1.5	-0.2	-1.4	-0.3	-1.1	-1.9	-1.4
Illnesses of father: High blood pressure	1.1	1.4	2.6	-1.5	-1.0	-0.7	-1.4	-1.6	-1.4	-1.4	-1.4	-0.7	-1.6	-1.0	-0.2	-1.4	-0.1	-1.5	-0.6	-0.8	-1.2	-1.2
Arm fat-free mass (left)	1.1	5.6	15.1	2.3	1.4	2.1	2.3	2.6	2.4	3.9	2.4	1.7	2.5	0.7	0.4	2.3	3.2	2.1	2.8	2.5	1.8	2.8
Ever had prostate specific antigen (PSA) test	1.1	1.2	6.5	-0.4	-1.9	-0.1	-0.4	-1.8	-0.5	0.2	-1.0	-0.9	-1.0	0.4	0.1	-0.5	-2.5	-1.3	-1.7	-1.1	0.3	-0.8
Alcohol drinker status: Previous	1.1	1.2	3.0	1.4	0.5	1.7	1.3	0.8	1.3	0.6	1.1	0.8	1.2	0.8	0.9	1.3	0.9	0.7	1.1	0.8	1.5	1.4
Arm predicted mass (left)	1.1	5.5	15.4	2.3	1.4	2.0	2.2	2.6	2.4	3.9	2.4	1.6	2.5	0.8	0.2	2.3	3.3	2.1	2.8	2.5	1.7	2.7
Hypothyroidism (self reported)	1.0	2.4	5.8	-1.3	-2.4	-1.0	-1.2	-1.9	-1.3	-0.3	-1.6	-1.8	-1.6	-0.2	-1.3	-1.2	-2.2	-1.9	-2.2	-1.5	-0.8	-1.4
Birth weight	1.0	2.2	7.5	-1.2	-1.6	-2.1	-1.3	-1.0	-1.2	0.2	-1.2	-2.5	-1.1	0.7	-0.3	-1.4	-2.3	-1.4	-1.4	-2.7	-0.4	-1.1
Arm fat-free mass (right)	1.0	5.3	16.6	2.2	1.2	2.1	2.2	2.5	2.4	4.1	2.3	1.5	2.4	0.7	0.2	2.2	3.0	2.0	2.8	2.4	1.7	2.7
Neck or shoulder pain in last month	1.0	1.4	2.5	-1.4	-1.4	-0.9	-1.4	-1.1	-1.4	-0.5	-1.2	-1.6	-1.3	-0.7	-1.2	-1.4	-0.7	-1.0	-1.0	-1.5	-1.1	-1.2
Arm predicted mass (right)	1.0	5.4	18.6	2.2	1.2	2.1	2.2	2.5	2.3	4.3	2.3	1.4	2.4	0.6	0.2	2.2	3.0	2.0	2.8	2.5	1.7	2.7
Illnesses of siblings: Diabetes	1.0	1.2	4.9	1.2	0.6	2.2	1.2	0.1	1.2	0.6	0.8	1.3	0.6	0.7	1.2	1.2	1.0	-0.0	0.9	1.4	1.4	1.1
Diastolic blood pressure, automated reading	1.0	3.2	4.5	1.9	1.5	1.5	1.9	2.1	1.9	1.1	2.1	1.9	2.0	1.3	2.1	1.8	0.7	2.1	1.8	1.4	2.0	1.9
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.2	-0.8	-1.1	-0.7	-0.9	-1.5	-1.0	-0.6	-1.2	-1.4	-1.1	0.4	-0.9	-1.0	-1.8	-1.4	-1.7	-1.6	-0.5	-1.1
Neuroticism (Nagel 2018)	0.9	2.2	5.4	-1.5	-2.0	-0.8	-1.4	-2.0	-1.4	-0.8	-1.7	-2.1	-1.8	0.1	-1.4	-1.5	0.0	-2.3	-1.4	-1.4	-1.2	-1.2
Prostate Cancer	0.9	1.2	3.4	-0.8	-1.5	-0.5	-0.8	-1.7	-0.9	-1.6	-1.1	-0.6	-1.1	0.2	-0.4	-0.9	-1.8	-0.6	-1.7	-0.9	-0.4	-1.1
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.4	-0.9	-0.6	-1.4	-0.9	-0.7	-0.8	-1.6	-0.7	-1.3	-0.7	1.1	-1.9	-0.8	-0.3	-0.4	-1.2	-1.1	-0.7	-0.8
Headache pain in last month	0.9	1.6	4.7	-1.2	-1.0	-1.3	-1.2	-1.2	-1.2	-0.7	-1.4	-1.9	-1.1	-1.1	-2.2	-1.2	-0.6	-1.4	-1.4	-1.2	-1.2	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.9	-1.1	-0.2	-1.2	-1.1	-1.0	-1.1	-0.9	-1.1	-0.9	-1.1	-1.7	-0.7	-1.1	-0.6	-0.9	-0.7	-0.5	-1.3	-1.2
Angina (self-reported)	0.9	1.2	2.3	-1.2	-0.3	-0.6	-1.2	-1.5	-1.2	-1.3	-1.3	-1.0	-1.3	-1.2	-0.9	-1.1	0.0	-1.5	-0.7	-0.8	-1.3	-1.0
Had major operations	0.9	1.0	4.5	-0.9	-0.5	-0.4	-0.9	-1.5	-0.9	-1.0	-1.2	-0.7	-1.2	-2.1	-0.2	-0.8	-0.3	-1.6	-0.9	-0.2	-1.0	-0.8
Eye problems/disorders: Cataract	0.9	1.1	3.2	-1.1	-0.6	-1.1	-1.2	-0.7	-1.1	-0.1	-1.0	-1.2	-0.9	-1.2	-1.8	-1.1	-0.2	-0.7	-1.1	-0.8	-1.1	-1.0
Back pain experienced in last month	0.9	1.3	2.4	-1.2	-0.1	-0.9	-1.2	-1.1	-1.3	-0.5	-1.2	-1.2	-1.3	-0.6	-1.6	-1.3	-1.2	-1.2	-1.5	-1.3	-0.9	-1.3
Leg fat percentage (left)	0.9	3.3	6.0	-1.7	-1.8	-1.6	-1.8	-2.4	-1.8	-0.9	-2.2	-1.9	-2.1	0.1	-1.5	-1.8	-1.8	-2.5	-2.0	-1.9	-1.3	-1.9
Age started oral contraceptive pill	0.9	1.2	3.7	1.1	0.7	0.8	1.1	0.9	1.1	0.9	0.9	1.0	1.1	0.8	0.2	1.2	1.9	0.7	1.0	1.6	1.3	1.1
Commuting to job workplace: Cycle	0.9	1.1	2.8	-1.3	-1.7	-1.1	-1.2	-1.0	-1.2	-1.3	-1.0	-0.3	-1.1	-0.6	-0.3	-1.3	-0.9	-0.3	-0.2	-0.5	-1.3	-1.4
Heel T-Score	0.8	6.2	20.4	-2.2	-1.3	0.5	-2.1	-4.5	-2.2	-0.6	-3.3	-1.9	-3.4	-4.0	-1.0	-2.2	-0.2	-4.5	-1.9	-0.3	-2.0	-2.1
BMI	0.8	4.4	7.7	-2.3	-2.5	-2.3	-2.4	-2.2	-2.3	-1.3	-2.3	-2.6	-2.2	0.2	-2.8	-2.3	-0.5	-2.1	-1.7	-2.0	-1.9	-2.1
Systolic Blood Pressure	0.8	4.1	6.8	2.2	1.0	1.7	2.3	2.6	2.3	0.6	2.6	2.5	2.4	1.7	1.9	2.2	0.6	2.6	1.4	1.7	2.4	2.3
Angina	0.8	1.0	1.7	-1.1	-0.1	-0.6	-1.1	-1.3	-1.1	-1.2	-1.2	-0.9	-1.2	-1.2	-1.0	-1.1	-0.1	-1.3	-0.7	-0.8	-1.2	-1.0
Chronic bronchitis/emphysema (father)	0.8	0.9	2.7	-0.8	-1.4	-0.6	-0.8	-1.1	-0.9	-0.2	-0.9	-0.5	-0.9	-0.5	0.4	-0.8	-1.6	-0.8	-1.4	-1.2	-0.4	-1.1
Qualifications: None of the above	0.8	1.8	3.8	1.5	0.5	1.4	1.6	1.3	1.6	0.2	1.6	1.9	1.3	1.5	1.0	1.6	0.9	1.2	0.6	1.4	1.4	1.5
Mouth/teeth dental problems	0.8	1.2	3.1	-1.0	0.3	-0.3	-1.0	-1.7	-1.0	-1.7	-1.3	-0.7	-1.3	-1.8	-0.4	-1.0	0.2	-1.5	-0.6	-0.1	-1.3	-0.9
Prospective memory result	0.8	0.9	2.1	-0.9	-1.4	-1.3	-1.0	-0.7	-1.0	-0.0	-0.8	-1.0	-0.7	-0.3	-1.1	-1.0	-1.2	-0.1	-1.0	-1.4	-0.8	-1.0
Blood clot in the leg (DVT)	0.8	1.0	2.3	-0.7	-0.7	-0.5	-0.7	-1.3	-0.8	-0.2	-1.0	-1.4	-1.0	0.3	-0.8	-0.8	-1.5	-1.4	-1.4	-1.4	-0.4	-0.9
Leg fat percentage (right)	0.8	3.1	5.4	-1.5	-1.9	-1.5	-1.7	-2.3	-1.7	-1.0	-2.0	-1.8	-1.9	0.5	-1.5	-1.7	-1.8	-2.3	-2.2	-2.0	-1.0	-1.8
Worry too long after embarrassment	0.8	1.3	2.4	-1.1	-1.2	-0.6	-1.2	-1.5	-1.1	-0.3	-1.3	-1.6	-1.3	0.1	-0.5	-1.1	-1.0	-1.6	-1.2	-1.5	-0.8	-1.0
Health satisfaction	0.8	1.1	2.4	-1.4	0.3	-1.1	-1.2	-1.0	-1.2	-0.6	-1.0	-1.1	-1.3	-0.9	-0.9	-1.4	0.2	-1.1	0.4	-0.8	-1.6	-1.1
Hypertension (Self-reported)	0.8	2.2	7.7	-1.5	-1.8	-1.9	-1.5	-1.4	-1.6	-2.8	-1.4	-0.4	-1.6	-0.5	-0.9	-1.5	-1.2	-1.1	-1.7	-1.1	-1.3	-1.7
Loneliness, isolation	0.8	1.2	6.2	0.6	1.8	1.1	0.8	0.7	0.8	1.2	0.8	0.6	0.6	0.2	-0.3	0.7	2.5	0.2	1.5	1.5	0.1	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.9	-1.1	-0.9	-0.7	-1.1	-1.4	-1.1	-0.6	-1.1	-1.0	-1.2	-0.9	-0.6	-1.1	0.0	-1.0	-0.0	-0.6	-1.3	-1.0
Medication: Gliclazide	0.8	0.9	3.8	-0.9	-1.2	-0.9	-0.9	-0.8	-0.9	-2.0	-0.8	-1.0	-0.8	-0.2	-0.2	-0.8	-1.0	-0.4	-1.1	-1.2	-0.5	-0.9
Miserableness	0.8	1.4	3.8	-0.9	-1.7	-0.3	-0.9	-1.4	-0.8	-1.0	-1.2	-1.8	-1.2	1.1	-1.7	-1.0	-0.5	-1.9	-1.3	-1.3	-0.6	-0.6
Pain type(s) experienced in last month: Hip pain	0.8	0.9	1.8	-1.1	-1.3	-0.7	-1.1	-0.9	-1.1	0.2	-1.0	-1.3	-1.1	-0.2	-0.9	-1.1	-0.7	-1.1	-0.5	-1.3	-1.1	-0.9
High cholesterol (Self-reported)	0.8	1.4	5.9	-0.8	-1.5	-0.5	-0.9	-1.4	-1.0	-2.4	-1.0	-0.5	-1.1	-0.9	-1.2	-0.8	-1.3	-0.9	-1.8	-0.9	-0.6	-1.1
Schizophrenia vs Biploar Disorder	0.7	0.9	5.6	1.1	0.3	0.8	1.0	0.6	1.0	-0.1	1.0	0.9	0.9	2.4	1.0	1.0	0.0	0.7	-0.3	0.1	1.4	0.8
Alzheimer’s Disease (including proxy)	0.7	1.0	1.8	1.0	0.8	0.8	0.9	1.2	0.9	1.4	1.1	0.7	1.1	1.0	1.2	0.9	0.0	1.2	1.0	0.3	1.1	0.9
Lung FVC	0.7	3.8	9.7	1.8	1.6	1.0	1.8	2.8	1.9	2.7	2.0	0.8	2.3	1.0	0.4	1.8	2.8	1.9	3.1	1.6	0.9	2.1
Ever used hormone-replacement therapy (HRT)	0.7	0.8	2.4	-0.6	-1.2	-0.9	-0.5	-0.9	-0.6	-0.9	-0.7	-1.0	-0.8	0.8	-0.4	-0.6	-1.3	-1.1	-1.5	-1.4	0.1	-0.5
Pack years adult smoking proportion	0.7	1.0	4.0	1.0	0.4	0.9	1.0	0.9	1.0	2.0	1.0	0.3	1.0	1.9	0.2	0.9	-0.5	0.8	0.1	-0.2	1.4	1.1
High blood pressure	0.7	2.0	6.8	-1.4	-1.7	-1.7	-1.4	-1.4	-1.5	-2.6	-1.3	-0.2	-1.5	-1.1	-0.8	-1.5	-0.8	-1.1	-1.5	-0.8	-1.4	-1.6
Number of incorrect matches in round	0.7	1.1	1.9	1.2	0.1	0.8	1.1	1.3	1.1	0.8	1.2	1.2	1.2	1.3	1.3	1.2	0.3	1.3	0.8	0.8	1.4	0.9
Had other major operations	0.7	0.8	2.1	-0.8	-1.5	-0.2	-0.8	-1.4	-0.9	0.1	-0.9	-1.0	-1.1	0.3	0.4	-0.8	-1.0	-1.2	-0.7	-1.1	-0.4	-0.9
Fluid intelligence score	0.7	1.5	3.9	1.0	1.7	1.1	1.1	1.4	1.1	1.3	1.3	1.5	1.3	-0.6	0.4	1.1	1.3	1.6	1.2	2.0	0.5	1.1
Medication: Amlodipine	0.7	1.0	3.6	-0.6	-1.7	-1.9	-0.7	0.1	-0.7	-0.8	-0.2	-0.6	-0.3	0.9	-1.9	-0.7	-0.8	0.5	-1.4	-1.0	-0.4	-0.9
Body fat percentage	0.7	2.9	9.3	-1.4	-1.6	-0.5	-1.5	-3.0	-1.6	-0.1	-2.2	-1.6	-2.2	0.2	-1.1	-1.5	-1.7	-3.0	-2.0	-1.4	-0.8	-1.7
Medication: Ibuprofen	0.7	0.9	2.1	-1.1	-0.1	-1.2	-1.1	-0.8	-1.1	-0.5	-1.1	-1.0	-1.0	-0.5	-0.6	-1.2	-0.1	-1.2	-0.4	-1.0	-1.4	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.6	-1.0	-0.3	-0.5	-1.0	-1.2	-1.0	-0.2	-1.2	-1.1	-1.2	-0.6	-0.6	-1.1	-0.5	-1.6	-0.5	-0.8	-1.1	-0.9
Qualifications: nursing, teaching	0.7	1.1	2.7	-1.1	-0.3	-1.4	-1.2	-0.8	-1.1	0.2	-1.1	-1.6	-0.9	-0.9	-1.3	-1.1	-1.3	-0.7	-0.7	-1.2	-0.9	-1.2
Unable to work because of sickness or disability	0.7	0.9	1.6	1.0	0.6	1.1	1.1	1.1	1.1	0.2	1.1	1.3	1.0	1.0	-0.0	1.0	0.4	1.3	0.1	0.8	0.9	1.1
Vascular/heart problems diagnosed by doctor	0.7	1.9	5.8	1.4	1.5	1.4	1.4	1.6	1.5	2.4	1.4	-0.0	1.6	1.4	0.8	1.4	0.6	1.2	1.5	0.5	1.5	1.6
Neuroticism (2016)	0.6	0.8	2.0	1.0	-0.0	1.1	1.1	1.1	1.1	0.6	1.1	0.3	0.9	1.3	0.1	1.2	-0.5	0.6	-0.3	0.2	1.4	1.1
Primary Biliary Cirrhosis	0.6	0.8	3.9	0.9	-0.9	0.1	0.9	1.0	0.9	0.0	1.0	0.3	1.1	2.0	0.3	0.8	0.0	1.2	-0.7	-0.5	1.4	0.7
Schizophrenia (2014)	0.6	1.3	4.5	1.1	-0.1	0.7	1.1	0.9	1.0	1.5	1.1	0.9	1.0	2.1	1.6	1.2	0.0	1.2	0.9	0.2	1.6	0.9
Blood Red Count	0.6	5.7	14.1	2.8	1.4	3.8	2.8	0.9	2.6	2.3	1.9	3.1	1.7	1.5	3.7	2.7	0.8	0.6	1.6	2.7	2.9	2.3
Trunk fat percentage	0.6	2.3	9.6	-1.0	-1.2	0.1	-1.1	-3.0	-1.2	0.6	-2.0	-1.3	-2.0	0.1	-0.6	-1.2	-1.6	-3.1	-1.7	-1.0	-0.4	-1.3
Townsend deprivation index at recruitment	0.6	0.8	1.8	0.9	0.4	0.7	1.1	1.4	1.1	1.3	1.1	0.7	1.0	0.9	-0.2	1.0	0.4	0.9	0.2	0.5	1.0	1.1
Qualifications: CSEs or equivalent	0.6	0.8	4.4	0.9	0.4	0.2	0.9	1.2	0.9	0.6	0.9	0.4	1.1	2.1	-0.3	0.8	-0.6	1.0	-0.3	-0.3	1.1	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	4.5	-1.0	-0.2	0.2	-0.9	-1.7	-0.9	-2.1	-1.4	-0.4	-1.4	-1.4	-1.3	-0.9	0.9	-1.8	-1.1	0.1	-1.1	-0.9
Allergy	0.6	1.3	6.1	0.3	1.3	-0.6	0.2	2.1	0.4	1.0	1.0	-0.1	1.2	0.3	-0.5	0.5	2.0	1.7	2.5	0.5	-0.3	0.7
Arm fat percentage (right)	0.6	2.5	6.5	-1.4	-1.6	-0.7	-1.5	-2.5	-1.5	-0.3	-2.0	-1.5	-1.9	0.3	-1.3	-1.5	-1.4	-2.4	-1.8	-1.4	-0.8	-1.6
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	6.3	1.2	1.0	1.6	1.2	1.3	1.3	2.5	1.1	0.6	1.3	-0.6	0.2	1.2	2.4	0.6	1.9	1.8	0.6	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	4.2	-0.6	-2.0	-0.8	-0.6	-0.4	-0.7	-0.4	-0.6	-1.5	-0.5	0.6	-1.1	-0.6	-1.6	-0.5	-1.2	-1.5	-0.2	-0.6
Loud music exposure frequency	0.6	0.7	1.7	0.8	0.5	1.2	0.9	0.3	0.8	0.6	0.7	1.0	0.6	0.4	1.3	0.8	0.4	0.6	1.2	0.9	0.7	0.8
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.3	-1.0	-1.8	-0.7	-1.0	-1.4	-1.0	-0.2	-1.2	-0.9	-1.2	-0.4	-1.0	-0.9	-1.8	-1.1	-1.5	-0.7	-0.7	-1.2
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.4	-0.6	-0.8	0.3	-0.5	-1.8	-0.7	-1.2	-1.0	0.4	-1.3	-0.7	0.9	-0.7	-0.8	-1.4	-1.1	-0.1	-0.3	-0.8
High blood pressure (siblings)	0.6	0.9	1.5	-1.1	-0.9	-0.8	-1.1	-1.1	-1.2	-1.2	-1.0	-0.3	-1.1	0.2	0.1	-1.1	-0.6	-0.8	-0.7	-1.0	-0.8	-1.2
Arm fat percentage (left)	0.6	2.4	6.4	-1.4	-1.7	-0.7	-1.5	-2.5	-1.5	0.1	-2.0	-1.6	-1.9	0.4	-1.3	-1.5	-1.5	-2.4	-1.7	-1.4	-0.8	-1.6
Financial situation satisfaction	0.6	0.7	4.3	0.5	1.1	0.4	0.6	0.7	0.6	0.0	0.6	0.6	0.6	0.2	0.5	0.6	2.1	0.3	1.6	0.9	0.2	0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.5	-0.7	-0.4	0.3	-0.7	-1.3	-0.7	0.4	-1.0	-0.5	-1.0	-1.6	-1.0	-0.7	0.6	-1.2	-0.1	0.3	-0.9	-0.7
Heart disease (siblings)	0.6	0.8	2.1	1.0	-0.1	1.2	0.9	0.4	0.9	-0.4	0.6	1.3	0.7	-0.4	0.6	0.9	1.4	0.1	0.7	1.4	0.7	0.9
Depressed Affect (Nagel 2018)	0.5	1.1	4.5	-1.0	-0.7	0.0	-0.9	-1.6	-0.8	-0.6	-1.2	-1.4	-1.3	-0.5	-1.4	-0.9	0.0	-2.1	-0.5	-0.3	-1.0	-0.5
Crohns Disease (2017)	0.5	1.0	1.8	1.2	0.8	1.3	1.1	1.1	1.1	0.8	1.0	1.2	1.2	0.7	0.0	1.1	0.9	1.1	0.6	1.3	0.9	1.0
Average weekly spirits intake	0.5	0.6	1.8	-0.6	-1.3	-0.9	-0.6	-0.6	-0.6	-0.4	-0.5	0.3	-0.5	-1.3	-0.8	-0.6	-1.1	0.0	-1.2	-0.3	-0.9	-0.8
Impedance of leg (right)	0.5	2.5	8.2	-0.9	-1.1	-0.0	-0.9	-2.6	-1.0	-2.8	-1.8	-0.7	-1.9	-0.2	0.9	-1.0	-2.2	-2.9	-2.2	-1.2	-0.3	-1.3
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.1	-0.5	-1.1	-0.8	-0.5	-1.0	-0.5	-1.5	-0.7	-0.3	-0.7	0.2	-0.2	-0.5	-1.2	-0.7	-1.0	-0.7	-0.3	-0.5
Body mass index (BMI)	0.5	2.3	5.1	-1.6	-1.4	-2.0	-1.8	-1.4	-1.7	-0.2	-1.6	-1.9	-1.4	-0.0	-2.3	-1.7	-0.7	-1.1	-1.3	-1.7	-1.5	-1.6
Impedance of leg (left)	0.5	2.5	9.5	-1.0	-0.8	0.0	-0.9	-2.7	-1.1	-2.5	-1.8	-0.6	-2.0	-0.7	1.0	-1.0	-2.0	-3.1	-1.8	-0.9	-0.5	-1.3
Alcohol usually taken with meals	0.5	0.8	2.8	-1.0	-0.5	-1.7	-1.0	-0.4	-1.0	-0.1	-0.8	-1.3	-0.7	-0.6	-1.4	-1.0	-0.6	-0.4	-0.6	-0.9	-1.1	-1.0
Heart attack	0.5	0.6	1.7	-0.7	-0.4	0.3	-0.6	-1.3	-0.7	0.4	-1.0	-0.6	-1.0	-1.3	-0.9	-0.7	0.4	-1.2	-0.3	0.2	-0.8	-0.7
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.2	-0.1	-1.8	0.1	-0.1	-1.3	-0.3	-0.3	-0.6	-0.5	-0.7	0.4	0.5	-0.2	-1.6	-1.2	-1.3	-1.1	0.4	-0.3
Impedance of arm (right)	0.5	2.1	10.4	0.1	-0.4	2.1	0.2	-2.9	-0.1	-0.9	-1.3	0.1	-1.5	0.0	1.8	0.0	-2.0	-3.2	-1.8	0.0	1.0	-0.3
Asthma	0.5	1.0	3.0	-0.0	-1.4	1.0	0.0	-1.7	-0.2	-1.5	-0.7	0.5	-0.9	-0.0	1.6	-0.2	-1.5	-1.2	-1.7	-0.4	0.7	-0.5
Medication: Cholesterol lowering	0.5	0.8	3.2	-0.7	-0.8	-0.1	-0.7	-1.2	-0.8	-1.8	-0.9	-0.2	-0.9	-0.7	-1.1	-0.7	-0.4	-0.9	-1.5	-0.5	-0.5	-0.8
Illnesses of mother	0.5	0.7	1.3	-0.8	-0.2	-0.7	-0.9	-0.9	-0.8	-0.8	-0.9	-1.1	-0.9	-0.0	-1.1	-0.8	-0.2	-1.1	-0.7	-0.7	-0.9	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	7.6	1.0	0.7	1.4	1.0	1.2	1.1	2.8	0.9	0.4	1.1	-0.6	0.3	1.0	2.3	0.6	1.9	1.6	0.4	1.3
Pulse wave reflection index	0.5	0.6	1.7	-0.7	-1.1	-0.8	-0.7	-0.9	-0.8	-0.7	-0.7	-0.3	-0.8	-1.3	0.2	-0.7	-0.9	-0.5	-0.3	-0.4	-0.7	-0.9
Heart disease (mother)	0.5	0.6	1.3	0.9	0.8	1.1	1.0	0.8	0.9	0.7	0.9	0.9	0.8	0.4	0.2	0.8	0.6	0.7	0.0	0.9	0.9	0.9
Mood swings	0.5	0.8	4.3	-0.7	-0.4	-0.1	-0.7	-0.8	-0.7	-1.0	-0.9	-1.4	-0.7	-0.8	-2.1	-0.7	0.5	-1.0	-0.9	-0.7	-1.1	-0.5
Fractured/broken bones in last 5 years	0.5	0.7	2.5	-0.6	-1.6	-0.5	-0.5	-1.0	-0.5	-0.7	-0.8	-1.1	-0.8	0.5	-0.3	-0.6	-1.0	-1.3	-0.9	-0.9	-0.1	-0.4
Worry (Nagel 2018)	0.4	0.8	3.9	-0.8	-2.0	-0.6	-0.7	-0.8	-0.7	-1.3	-0.7	-1.1	-0.9	0.5	-0.5	-0.8	0.0	-0.8	-0.9	-1.0	-0.5	-0.8
Age at First Birth	0.4	0.5	2.7	-0.4	0.2	-1.0	-0.6	0.0	-0.5	-1.3	-0.4	-0.3	-0.1	-1.2	-1.6	-0.5	0.0	0.4	-0.1	0.2	-1.0	-0.5
Crohns Disease (2012)	0.4	0.6	1.5	0.8	0.3	1.2	0.8	0.8	0.8	1.2	0.6	0.6	0.7	-0.0	-0.6	0.8	0.0	0.4	0.6	1.2	0.4	0.9
Smoking Status	0.4	1.0	5.7	1.1	-0.2	1.1	1.1	0.7	1.1	0.7	0.9	0.2	1.0	2.4	0.4	1.1	0.2	0.2	0.4	0.1	1.6	1.1
Respiratory disease	0.4	1.0	4.2	-0.1	-0.4	0.7	-0.0	-1.6	-0.2	-2.0	-0.7	0.4	-0.9	0.3	1.1	-0.2	-1.4	-1.3	-2.1	-0.6	0.6	-0.5
Hand grip strength (left)	0.4	1.2	5.7	0.4	1.6	-1.0	0.4	2.4	0.5	1.3	1.1	-0.8	1.4	0.3	-0.8	0.5	1.1	1.5	1.2	-0.5	0.2	0.9
Diabetes (mother)	0.4	0.5	1.5	0.7	0.9	0.4	0.6	0.9	0.6	0.5	0.8	1.1	0.9	0.2	0.6	0.7	0.2	1.2	0.3	0.7	0.7	0.6
Current tobacco smoking	0.4	0.6	5.4	0.7	-0.2	0.8	0.7	0.6	0.7	0.5	0.6	-0.4	0.7	2.3	-0.5	0.8	-0.0	0.1	0.0	-0.4	1.1	0.9
Average weekly fortified wine intake	0.4	0.4	1.9	0.3	1.0	0.8	0.4	0.5	0.4	0.5	0.5	-0.0	0.4	-0.6	0.5	0.6	1.0	0.2	1.4	0.6	0.3	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.7	-0.7	-0.5	-1.1	-0.8	-0.0	-0.7	-0.3	-0.4	-0.8	-0.4	0.3	-1.2	-0.7	-0.8	0.1	-1.1	-1.3	-0.7	-0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.8	0.6	0.7	0.9	0.7	0.3	0.7	-0.5	0.6	0.7	0.4	1.3	0.6	0.6	0.6	0.2	0.4	0.4	0.8	0.7
Number of live births	0.4	0.6	2.0	-0.8	-0.2	-0.6	-0.7	-1.3	-0.7	-0.2	-1.0	-0.9	-1.1	0.2	-0.3	-0.8	-0.4	-1.4	-0.3	-0.6	-0.5	-0.7
Impedance of arm (left)	0.4	1.8	7.6	0.4	-0.2	2.5	0.5	-2.5	0.2	-0.0	-0.9	0.4	-1.2	0.2	2.2	0.3	-1.8	-2.8	-1.0	0.4	1.2	-0.1
Length of working week for main job	0.4	0.5	2.1	-0.6	-0.3	-1.2	-0.6	-0.1	-0.6	0.2	-0.4	-0.6	-0.4	-0.7	-1.5	-0.5	-0.8	-0.1	-1.1	-0.6	-0.7	-0.6
Pulse wave peak to peak time	0.4	0.5	3.7	0.5	0.6	0.9	0.6	0.4	0.6	0.5	0.4	0.8	0.4	0.2	0.7	0.5	1.9	0.0	0.9	1.0	0.3	0.7
Age at last live birth	0.4	0.6	3.8	-0.0	1.7	0.4	0.2	0.3	0.2	0.3	0.3	0.4	0.1	-0.4	-0.5	0.1	1.9	0.3	1.0	1.1	-0.5	0.2
Asthma (self-reported)	0.4	0.9	2.7	0.1	-1.0	1.1	0.1	-1.6	-0.1	-1.2	-0.6	0.6	-0.8	-0.2	1.7	-0.0	-1.5	-1.1	-1.6	-0.2	0.8	-0.4
Commuting to job workplace: Public transport	0.4	0.4	2.1	0.1	-0.0	0.7	0.1	0.1	0.1	0.4	0.1	0.8	0.1	-1.5	0.6	0.2	1.2	0.2	1.1	1.3	-0.3	0.1
Basal cell carcinoma (self-reported)	0.4	0.4	2.8	0.0	0.3	-0.5	-0.1	0.1	-0.2	-0.2	0.1	-0.5	0.1	1.2	0.3	-0.1	-1.7	0.2	-1.0	-1.3	0.6	-0.3
Impedance of whole body	0.4	1.9	9.1	-0.1	-0.4	1.5	-0.0	-2.7	-0.3	-1.0	-1.3	0.0	-1.6	-0.1	1.9	-0.2	-2.1	-3.0	-1.4	-0.2	0.6	-0.6
Depression (Nagel 2018)	0.3	0.4	1.6	-0.6	-0.8	0.3	-0.6	-1.3	-0.6	-0.2	-0.8	-0.4	-0.9	-1.0	-0.2	-0.7	0.0	-0.8	-0.1	0.0	-0.7	-0.5
Ulcerative Colitis (UC)	0.3	0.6	4.8	-0.1	-1.0	-0.8	-0.2	0.0	-0.2	0.4	-0.2	-0.7	-0.0	2.2	-0.8	-0.2	-1.2	-0.1	-0.9	-0.9	0.4	-0.4
Bipolar Disorder (2011)	0.3	0.3	1.7	0.3	0.8	0.4	0.5	0.4	0.4	1.3	0.5	0.6	0.2	0.3	0.9	0.4	0.0	0.1	0.7	0.4	0.4	0.4
Allergy or Eczema	0.3	0.7	2.8	0.0	-1.7	0.7	0.0	-1.4	-0.1	-0.5	-0.5	0.6	-0.6	-1.3	0.8	-0.2	-1.5	-0.8	-1.5	0.2	0.0	-0.4
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.0	-0.7	-1.0	-0.2	-0.6	-0.9	-0.6	0.2	-0.6	-0.5	-0.7	-0.6	-0.8	-0.6	0.1	-0.6	-0.2	-0.4	-0.8	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.0	-0.6	-1.0	0.4	-0.5	-1.0	-0.5	0.3	-0.6	-0.5	-0.8	-0.9	-0.8	-0.6	-0.3	-0.7	-0.7	-0.3	-0.7	-0.4
Nervous feelings	0.3	0.5	2.3	-0.5	-1.1	-0.5	-0.5	-0.5	-0.5	-1.4	-0.3	-0.2	-0.5	0.4	-0.0	-0.6	-1.5	-0.1	-0.9	-0.8	-0.3	-0.7
Pain all over the body in last month	0.3	0.3	1.9	-0.2	-0.9	-0.7	-0.2	-0.1	-0.3	0.0	0.0	0.4	-0.1	-1.1	-0.1	-0.2	-1.4	0.8	-0.7	-0.3	-0.4	-0.4
Medication: Ramipril	0.3	0.4	0.7	0.6	0.3	0.7	0.7	0.5	0.6	0.7	0.7	0.4	0.7	0.7	0.3	0.6	0.2	0.8	0.8	0.3	0.6	0.6
Weight	0.3	1.5	9.4	1.2	0.2	1.7	1.2	0.4	1.2	3.1	0.8	0.5	0.9	0.9	0.1	1.1	1.3	0.1	1.2	1.2	1.2	1.4
Time employed in main current job	0.3	0.4	1.5	0.6	0.4	0.5	0.6	0.7	0.6	0.3	0.7	0.9	0.7	-0.1	-0.1	0.6	0.0	1.2	0.7	0.8	0.0	0.4
Alcohol intake versus 10 years previously	0.3	0.4	3.6	-0.5	-0.8	-0.4	-0.4	-0.2	-0.4	-1.9	-0.1	0.8	-0.4	0.8	0.1	-0.5	0.0	0.4	-0.3	0.2	-0.5	-0.8
Pulse rate	0.3	0.5	3.7	0.1	1.9	-0.0	0.0	0.5	0.1	0.5	0.1	-1.0	0.3	1.0	-1.5	-0.0	-0.4	-0.1	-0.5	-0.7	0.1	0.2
Depression (self-reported)	0.3	0.4	0.9	-0.5	-0.7	-0.6	-0.5	-0.8	-0.5	-0.9	-0.7	-0.2	-0.6	-0.5	-0.9	-0.5	0.6	-0.5	-0.4	0.4	-0.7	-0.7
Breastfed as a baby	0.3	0.4	1.6	0.2	0.6	0.2	0.3	0.4	0.3	0.0	0.3	0.6	0.3	-0.8	1.2	0.3	0.7	0.4	1.3	0.9	0.1	0.3
Hair/balding pattern: Pattern 4	0.3	0.8	2.7	-0.2	1.3	0.7	-0.1	-1.1	-0.2	-1.5	-0.5	0.8	-0.6	-0.4	1.2	-0.1	-1.6	-0.6	-1.5	-0.5	-0.1	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.0	-0.7	-0.9	-0.9	-0.7	-0.7	-0.7	-0.4	-0.7	-1.0	-0.7	-1.0	-0.1	-0.7	-0.0	-0.7	0.3	-0.4	-0.6	-0.6
Wheeze or whistling in the chest in last year	0.3	0.6	2.1	0.2	-1.0	0.4	0.2	-1.1	0.1	-0.9	-0.4	-0.3	-0.4	1.1	0.5	0.1	-1.2	-1.1	-1.4	-0.8	1.1	-0.0
Age at first live birth	0.3	0.6	1.8	-0.8	0.8	-0.6	-0.8	-0.2	-0.7	-0.8	-0.5	-0.5	-0.5	-1.1	-1.3	-0.7	1.0	-0.1	0.4	0.2	-1.4	-0.7
Medication: Seretide 50 evohaler	0.3	0.3	2.2	0.3	-0.6	0.8	0.4	0.3	0.4	-1.5	0.5	1.0	0.3	0.3	0.5	0.3	0.2	0.5	-0.1	0.3	0.4	0.3
Mean time to correctly identify matches	0.3	0.5	3.0	0.4	-0.2	0.9	0.4	-0.4	0.4	1.1	-0.0	-0.0	-0.0	0.3	1.7	0.4	0.6	-0.7	1.6	0.5	0.4	0.4
Family relationship satisfaction	0.3	0.4	1.9	-0.4	0.7	-0.0	-0.3	-0.5	-0.3	-1.0	-0.3	0.5	-0.5	-0.8	0.0	-0.4	1.4	-0.2	0.6	0.8	-0.8	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.7	-0.7	0.6	-0.4	-0.6	-0.4	-0.5	0.1	-0.6	-0.9	-0.6	-0.8	-0.6	-0.6	0.4	-0.7	0.2	-0.2	-0.8	-0.3
Smoking status: Previous	0.3	0.5	2.3	0.7	-0.4	0.3	0.7	0.3	0.7	0.1	0.6	1.4	0.6	0.6	1.5	0.6	0.3	0.6	0.2	0.8	1.0	0.5
Osteoporosis (self-reported)	0.3	0.3	1.6	0.5	0.5	0.8	0.4	0.2	0.4	0.7	0.4	0.3	0.4	0.8	0.2	0.6	1.3	0.2	0.8	0.5	0.4	0.5
Smoking status: Current	0.3	0.5	5.4	0.5	-0.2	0.6	0.5	0.4	0.5	0.4	0.4	-0.6	0.5	2.3	-0.8	0.5	-0.1	-0.0	-0.1	-0.6	0.8	0.6
Average weekly champagne plus white wine intake	0.3	0.4	2.0	0.6	-0.5	0.6	0.5	0.4	0.6	1.4	0.4	-0.1	0.6	-0.3	0.1	0.6	0.8	0.2	0.5	0.7	0.5	0.7
Ever taken oral contraceptive pill	0.3	0.4	0.6	-0.8	-0.2	-0.3	-0.8	-0.7	-0.7	-0.4	-0.7	-0.7	-0.7	-0.6	-0.7	-0.7	0.6	-0.4	0.2	-0.2	-0.8	-0.5
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.7	0.5	0.9	-0.1	0.5	0.8	0.5	0.3	0.7	0.1	0.6	1.3	-0.3	0.6	0.4	0.5	-0.0	-0.2	0.7	0.8
Medication: Lisinopril	0.3	0.3	1.8	-0.1	1.4	0.3	-0.2	-0.9	-0.2	-0.6	-0.4	0.6	-0.5	-0.6	-0.4	-0.1	0.3	-0.7	-0.9	0.5	-0.3	-0.2
Medication: Atorvastatin	0.3	0.4	2.2	0.2	-0.3	0.8	0.2	-0.3	0.1	0.4	-0.0	1.0	-0.1	-1.3	-0.3	0.2	1.1	0.0	0.2	1.5	-0.4	-0.1
Pack years of smoking	0.3	0.5	2.6	0.6	0.2	0.5	0.6	0.5	0.5	1.6	0.6	0.1	0.5	1.5	0.0	0.5	-0.4	0.3	-0.2	-0.3	0.9	0.7
Bipolar Disorder or Schizophrenia	0.2	0.5	2.0	0.6	-0.4	-0.1	0.6	0.7	0.5	1.4	0.7	0.5	0.6	0.7	1.1	0.5	0.0	1.1	0.7	0.1	0.9	0.4
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.4	0.8	1.0	0.9	0.8	0.6	0.8	1.6	0.7	0.9	0.7	-0.2	-0.1	0.8	0.0	1.0	0.6	1.5	0.4	0.7
Schizophrenia (2018)	0.2	0.4	1.4	0.4	-0.6	-0.1	0.5	0.6	0.4	1.0	0.7	0.4	0.4	1.0	1.2	0.4	0.0	0.8	0.7	-0.1	0.8	0.3
Major Depression (MDD)	0.2	0.2	1.1	0.2	-0.1	-0.7	0.2	0.7	0.3	-1.0	0.5	0.2	0.5	0.4	0.2	0.4	0.0	0.7	-0.2	-0.3	0.4	0.2
Reaction Time	0.2	0.4	1.7	0.4	0.3	0.8	0.3	-0.3	0.3	1.2	0.0	-0.3	0.1	0.1	1.3	0.3	0.3	-0.5	1.2	0.3	0.4	0.4
LDL Cholesterol	0.2	0.3	2.2	-0.1	-0.4	-0.2	-0.1	-0.6	-0.2	-0.6	-0.3	-0.4	-0.3	1.5	-0.6	-0.2	0.0	-0.4	-1.3	-0.7	0.2	-0.4
Triglycerides	0.2	0.3	2.5	-0.3	1.6	0.6	-0.0	-0.5	-0.1	-0.1	-0.2	0.3	-0.4	-0.5	-0.6	-0.0	0.0	-0.7	0.5	0.9	-0.6	0.0
Ulcerative Colitis	0.2	0.3	1.4	-0.3	-1.2	-0.5	-0.3	-0.3	-0.3	1.0	-0.4	-0.8	-0.3	0.7	-0.7	-0.3	0.0	-0.5	0.0	-0.3	-0.3	-0.4
Blood Eosinophil Count	0.2	1.5	6.6	1.1	0.7	1.9	1.1	0.2	1.1	-0.5	0.5	1.9	0.5	-2.6	0.6	1.2	1.6	-0.4	-0.2	2.1	0.4	1.0
Blood White Count	0.2	1.5	7.7	0.1	-2.5	0.3	0.2	-0.6	0.0	-2.8	0.2	1.4	-0.2	0.4	1.6	0.1	-2.6	0.8	-0.8	0.1	0.7	-0.6
Waist Hip Ratio (WHR)	0.2	1.0	4.0	0.2	-1.2	-0.5	-0.0	-0.2	-0.1	-2.0	0.1	0.5	0.1	1.9	0.8	-0.2	-1.8	0.9	-1.6	-1.0	0.9	-0.4
Chronotype (morning person)	0.2	0.4	3.0	-0.0	1.0	-0.8	-0.2	0.6	-0.2	-0.7	0.2	-0.3	0.3	-0.6	-0.2	-0.1	-1.7	0.7	-0.4	-1.0	-0.2	-0.2
Tanning	0.2	2.7	4.2	1.9	1.4	2.0	2.0	1.6	2.0	1.2	1.6	1.2	1.6	1.4	1.0	1.9	1.7	0.6	1.5	1.8	1.9	2.0
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.8	0.2	-1.2	0.4	0.2	-0.9	0.0	-0.2	-0.2	0.4	-0.3	-0.5	0.4	-0.0	-1.6	-0.4	-1.7	-0.1	0.5	-0.2
Supplements: Glucosamine	0.2	0.3	0.6	0.7	0.5	0.8	0.6	0.3	0.6	0.3	0.3	0.3	0.5	-0.4	0.5	0.7	-0.0	0.1	0.4	0.6	0.7	0.7
Medication: Atenolol	0.2	0.2	2.5	-0.0	-1.6	-0.2	-0.0	-0.5	-0.1	-0.4	-0.1	0.3	-0.2	-0.3	-0.0	-0.1	-0.2	0.0	-0.7	0.0	-0.1	-0.1
Trunk fat mass	0.2	0.7	4.4	0.3	-0.4	1.3	0.2	-1.4	0.2	2.1	-0.6	-0.2	-0.5	0.6	0.0	0.2	-0.2	-1.7	-0.3	0.3	0.7	0.2
Past tobacco smoking	0.2	0.4	1.6	-0.6	0.8	-0.0	-0.6	-0.4	-0.6	0.3	-0.5	-1.0	-0.6	-1.3	-0.8	-0.5	-0.2	-0.6	0.0	-0.5	-0.8	-0.3
Hearing difficulty/problems with background noise	0.2	0.4	1.7	0.3	-1.2	-0.1	0.2	0.2	0.2	-0.2	0.4	0.9	0.3	1.3	0.5	0.2	-1.0	1.1	0.0	0.1	0.3	-0.0
Illnesses of siblings	0.2	0.3	1.3	-0.0	-0.1	-0.7	0.0	0.7	0.0	1.1	0.3	-1.1	0.4	0.3	-0.8	-0.0	-0.9	0.6	0.0	-0.8	-0.0	0.1
Father’s age at death	0.2	0.3	1.3	0.3	-0.3	0.9	0.3	0.2	0.4	1.1	0.3	0.7	0.2	-0.3	1.0	0.3	0.5	0.3	0.6	0.8	0.4	0.3
Worrier / anxious feelings	0.2	0.4	1.3	-0.5	-0.9	-0.1	-0.5	-0.7	-0.5	-1.1	-0.5	-0.3	-0.6	-0.3	0.4	-0.5	-1.0	-0.6	-0.7	-0.7	-0.3	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.2	-0.4	0.8	-0.2	-0.3	0.1	-0.2	-1.1	0.0	0.5	-0.2	-1.0	0.1	-0.4	0.3	0.2	0.3	0.2	-0.6	-0.2
Arm fat mass (right)	0.2	0.7	2.1	-0.6	-1.1	-0.2	-0.7	-1.5	-0.7	0.9	-1.1	-0.9	-1.0	0.3	-1.0	-0.8	-0.3	-1.5	-0.7	-0.5	-0.3	-0.7
Tense / ‘highly strung’	0.2	0.3	1.0	-0.5	-1.0	-0.5	-0.4	0.2	-0.4	-0.2	-0.0	-0.6	-0.1	0.6	-0.6	-0.5	-0.9	0.5	-0.6	-0.7	-0.2	-0.4
Birth weight of first child	0.2	0.4	2.0	0.3	1.0	0.3	0.3	0.0	0.3	1.4	0.3	0.0	0.2	0.0	0.7	0.3	-1.4	0.2	0.0	-0.4	0.6	0.3
Glaucoma (self-reported)	0.2	0.3	2.5	-0.2	0.3	0.3	-0.1	-0.2	-0.1	-0.5	-0.0	0.5	-0.2	-1.6	0.5	-0.1	0.7	0.0	0.4	0.7	-0.5	0.1
Comparative body size at age 10	0.2	0.6	1.9	-0.5	-1.0	-0.4	-0.6	-0.7	-0.6	0.0	-0.8	-1.4	-0.6	-1.1	-0.9	-0.6	-0.6	-1.0	-0.7	-1.0	-0.5	-0.3
Medication: Omeprazole	0.2	0.2	1.1	0.4	-0.3	0.2	0.4	0.1	0.4	0.9	0.3	-0.2	0.2	1.1	0.4	0.3	-0.6	-0.2	-0.0	-0.3	1.0	0.4
Pulse rate, automated reading	0.2	0.6	3.9	-0.3	2.0	-0.5	-0.4	0.5	-0.3	0.1	-0.1	-1.4	0.0	1.1	-1.4	-0.3	0.3	-0.3	-0.5	-1.2	-0.2	-0.1
Number of full sisters	0.2	0.2	0.6	0.2	-0.0	0.8	0.3	-0.1	0.3	-0.1	0.2	0.7	0.1	-0.5	0.8	0.3	0.7	0.2	0.2	0.7	0.4	0.4
Chest pain or discomfort	0.2	0.3	1.4	-0.1	-0.6	0.0	-0.1	-0.3	-0.1	0.6	-0.1	-0.4	-0.2	1.2	0.5	-0.2	-1.0	-0.2	-0.7	-1.0	0.4	-0.1
Leg pain on walking	0.2	0.2	0.6	-0.4	-0.3	-0.3	-0.5	-0.2	-0.4	0.7	-0.3	-0.8	-0.2	-0.4	-0.5	-0.4	-0.4	-0.1	0.3	-0.5	-0.8	-0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.0	0.3	1.0	0.0	0.3	0.8	0.3	-0.3	0.5	-0.0	0.5	0.4	-0.0	0.3	-0.1	0.8	-0.3	-0.6	0.3	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.1	0.4	-0.3	0.5	0.3	0.1	0.3	1.0	0.1	-0.4	0.2	0.5	0.5	0.4	-0.4	-0.3	-0.2	-0.3	0.7	0.3
Illnesses of father: Heart disease	0.2	0.3	0.8	0.5	0.7	0.3	0.5	0.9	0.5	0.6	0.6	-0.2	0.7	0.8	-0.8	0.6	0.0	0.5	0.0	-0.1	0.6	0.7
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.8	-0.3	-0.6	-0.1	-0.2	-0.8	-0.3	-0.9	-0.4	-0.4	-0.6	0.1	0.5	-0.2	-0.6	-0.8	-0.3	-0.4	0.3	-0.2
Commuting to job workplace: Walk	0.2	0.3	1.1	0.5	1.0	0.1	0.4	0.5	0.4	0.8	0.3	-0.2	0.6	0.2	-1.0	0.4	-0.2	0.3	0.2	0.3	0.4	0.4
Osteoarthritis (self-reported)	0.2	0.3	0.7	-0.5	-0.7	-0.4	-0.4	-0.4	-0.4	-0.2	-0.4	-0.8	-0.5	0.5	-0.7	-0.4	-0.6	-0.8	-0.5	-0.6	-0.1	-0.3
Hearing aid user	0.2	0.2	0.9	0.6	-0.3	0.8	0.6	-0.1	0.5	-0.4	0.2	0.6	0.3	-0.1	-0.1	0.6	-0.1	-0.2	-0.9	0.4	0.6	0.4
Mother’s age at death	0.2	0.2	1.2	-0.2	-0.2	0.3	-0.3	-0.5	-0.3	0.3	-0.4	-0.0	-0.3	-0.8	0.8	-0.2	0.3	-0.5	1.1	0.4	-0.4	-0.3
Eye problems/disorders: Glaucoma	0.2	0.3	0.9	0.4	0.3	0.6	0.4	0.3	0.4	-0.2	0.5	0.9	0.4	-0.6	0.9	0.4	0.2	0.6	0.7	0.6	0.2	0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.3	0.4	0.0	0.1	0.4	0.2	0.3	1.2	0.2	-0.3	0.2	1.1	0.4	0.2	-1.1	-0.1	0.1	-0.4	1.0	0.2
Bipolar Disorder (2018)	0.1	0.2	1.0	0.4	-0.1	0.0	0.3	0.4	0.3	1.0	0.3	0.2	0.4	-0.1	0.3	0.3	0.0	0.8	0.2	0.3	0.4	0.2
Alzheimer’s Disease (in mother)	0.1	0.2	0.5	0.4	0.6	0.4	0.4	0.5	0.4	0.5	0.4	0.2	0.4	0.1	0.7	0.3	-0.5	0.3	0.3	-0.2	0.5	0.4
Alzheimer’s Disease (in father)	0.1	0.1	0.7	0.0	0.0	-0.0	-0.1	-0.1	-0.0	0.7	-0.0	-0.2	0.0	0.8	0.4	-0.0	-0.2	0.0	0.6	-0.2	0.2	-0.1
Irritable Bowel Disease (IBD)	0.1	0.3	3.0	0.5	-0.3	0.1	0.4	0.5	0.4	0.3	0.3	0.1	0.6	1.7	-0.7	0.4	-0.4	0.5	-0.4	0.1	0.7	0.2
Mean Putamen Volume	0.1	0.1	0.6	0.1	-0.6	0.0	0.0	-0.4	0.0	0.5	-0.1	0.4	-0.1	0.5	0.8	0.1	0.0	0.1	0.1	0.1	0.1	-0.2
Fasting Glucose	0.1	0.1	0.8	-0.2	-0.1	0.2	-0.1	-0.4	-0.1	0.2	-0.2	0.2	-0.2	0.9	-0.7	-0.2	0.0	-0.2	-0.2	0.4	-0.4	-0.2
HDL Cholesterol	0.1	0.2	0.9	0.6	0.2	0.3	0.5	0.2	0.4	0.3	0.3	-0.1	0.4	0.9	0.5	0.5	0.0	0.1	-0.5	-0.4	1.0	0.4
Rheumatoid Arthritis	0.1	0.1	0.4	-0.1	-0.6	-0.6	-0.0	0.5	-0.0	-0.2	0.2	-0.3	0.2	0.2	-0.3	-0.0	0.0	0.5	-0.2	-0.6	0.1	0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.2	1.0	-0.1	-0.3	0.6	0.1	-0.1	0.1	-0.2	0.1	0.6	-0.2	-0.3	0.0	0.0	0.0	-0.3	0.9	1.0	-0.4	0.2
Stomach or abdominal pain in last month	0.1	0.2	1.0	0.3	0.2	0.7	0.4	-0.1	0.3	0.5	0.1	0.0	0.1	0.6	1.0	0.3	-0.2	-0.5	0.4	-0.1	0.4	0.4
Medication: Levothyroxine sodium	0.1	0.1	0.4	0.3	-0.1	0.6	0.3	-0.2	0.3	0.6	0.0	0.0	0.1	0.3	-0.6	0.4	-0.2	0.1	-0.5	0.5	0.4	0.1
Waist circumference	0.1	0.5	1.4	-0.3	-1.2	-0.2	-0.4	-1.1	-0.4	0.4	-0.6	-0.7	-0.6	0.9	-0.7	-0.4	-0.6	-0.8	-0.9	-0.7	0.3	-0.4
Had menopause	0.1	0.1	1.1	0.3	-0.2	-0.1	0.2	0.1	0.2	0.3	0.2	0.3	0.2	1.0	0.5	0.3	0.2	0.2	0.1	0.2	0.6	0.1
Financial difficulties in last 2 years	0.1	0.1	0.5	-0.2	0.4	0.0	-0.1	-0.0	-0.1	-0.4	-0.1	-0.2	-0.3	0.4	-0.0	-0.2	0.4	-0.7	0.1	-0.4	-0.0	0.1
Hip circumference	0.1	0.5	2.7	-0.0	-0.6	0.6	-0.1	-1.2	-0.1	1.6	-0.6	-0.7	-0.6	-0.0	-0.4	-0.1	0.3	-1.6	0.1	0.2	0.2	0.1
Hair/balding pattern: Pattern 3	0.1	0.2	1.2	0.0	-0.1	0.4	-0.1	-0.1	-0.1	0.2	0.0	1.1	-0.0	-0.4	0.8	-0.1	-0.3	0.5	-0.0	0.5	-0.4	-0.4
Noisy workplace	0.1	0.2	1.2	0.1	-0.3	-0.0	0.0	0.1	0.0	0.8	0.0	-0.2	0.1	-0.5	0.6	0.0	-1.1	0.2	0.5	-0.4	-0.1	0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.9	-0.5	-0.9	-0.8	-0.6	-0.6	-0.6	0.1	-0.5	-0.6	-0.4	-0.1	-0.1	-0.6	-0.8	-0.0	-0.2	-0.5	-0.5	-0.7
Pulse wave Arterial Stiffness index	0.1	0.2	2.6	0.1	-0.3	-0.2	-0.0	0.0	-0.0	0.1	0.0	-0.3	0.1	-0.0	-0.2	0.0	-1.6	0.2	-0.4	-0.4	0.2	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.8	0.0	-0.8	-0.1	-0.1	0.1	-0.1	0.3	0.1	-0.2	0.2	-0.9	0.8	-0.1	-0.4	0.6	0.6	-0.2	0.0	-0.0
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	1.7	0.2	0.2	0.3	0.2	0.4	0.2	1.3	0.2	-0.1	0.2	-0.5	-0.1	0.1	-0.1	0.2	0.4	0.0	0.1	0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.5	-0.4	0.3	0.2	-0.3	-0.7	-0.3	0.3	-0.4	-0.0	-0.6	-0.4	0.2	-0.4	0.3	-0.5	0.1	0.2	-0.3	-0.2
Number of full brothers	0.1	0.1	1.0	-0.1	-0.4	-0.7	-0.1	-0.0	-0.1	-1.0	-0.1	0.0	-0.0	0.2	-0.6	-0.1	0.4	-0.0	-0.5	-0.2	-0.1	-0.1
Qualifications: College or University degree	0.1	0.3	0.9	-0.4	-0.3	0.2	-0.4	-1.0	-0.3	0.7	-0.6	-0.5	-0.6	-0.5	0.7	-0.4	0.3	-0.9	0.7	0.4	-0.3	-0.4
Whole body fat mass	0.1	0.6	2.5	-0.1	-0.8	0.6	-0.2	-1.5	-0.2	1.5	-0.8	-0.5	-0.7	0.7	-0.4	-0.2	-0.3	-1.6	-0.5	-0.1	0.3	-0.2
Leg fat mass (right)	0.1	0.3	1.3	-0.1	-0.8	0.1	-0.2	-0.9	-0.2	1.2	-0.6	-0.5	-0.5	0.8	-0.7	-0.2	-0.1	-1.0	-0.5	-0.4	0.2	-0.1
Overall health rating	0.1	0.3	1.1	-0.5	-1.0	0.0	-0.4	-0.6	-0.4	-1.0	-0.4	0.3	-0.6	-0.3	-0.9	-0.4	0.0	-0.4	-0.8	0.0	-0.6	-0.5
Friendships satisfaction	0.1	0.1	0.5	0.0	-0.2	-0.1	0.0	0.4	0.1	0.6	0.1	0.3	0.2	-0.5	-0.7	-0.0	0.6	0.4	0.5	0.7	-0.2	0.1
Arm fat mass (left)	0.1	0.5	1.6	-0.4	-0.9	0.0	-0.5	-1.2	-0.5	1.3	-0.9	-0.8	-0.7	0.4	-0.9	-0.5	-0.1	-1.2	-0.5	-0.3	-0.1	-0.4
Wears glasses or contact lenses	0.1	0.1	0.4	0.4	0.4	0.5	0.4	0.1	0.3	-0.3	0.3	0.0	0.2	0.3	0.1	0.4	-0.2	-0.1	-0.1	0.0	0.6	0.5
Medication: Blood pressure	0.1	0.2	0.5	0.3	-0.7	-0.2	0.2	0.1	0.2	-0.7	0.2	0.2	0.1	0.7	0.4	0.2	-0.7	-0.1	-0.4	-0.3	0.5	0.2
Ever smoked	0.1	0.2	1.3	0.3	-1.1	0.1	0.4	0.1	0.3	-0.4	0.2	0.5	0.2	1.2	0.4	0.3	0.2	0.1	0.0	0.3	0.5	0.1
Irritability	0.1	0.2	0.9	-0.2	-0.4	0.5	-0.2	-0.5	-0.1	-0.4	-0.3	-0.5	-0.3	-0.3	-1.0	-0.3	0.6	-0.7	-0.0	0.2	-0.4	0.1
Risk taking	0.1	0.1	0.5	-0.3	-0.6	-0.1	-0.2	-0.3	-0.2	-0.1	-0.2	-0.7	-0.2	0.4	0.1	-0.2	0.5	-0.5	0.3	-0.5	-0.3	-0.0
Supplements: Calcium	0.1	0.1	0.6	-0.2	-0.6	0.1	-0.2	-0.4	-0.2	0.7	-0.3	-0.5	-0.3	0.2	-0.5	-0.1	-0.3	-0.5	-0.1	-0.2	-0.1	-0.1
Leg fat mass (left)	0.1	0.4	1.5	-0.2	-0.8	0.1	-0.3	-1.1	-0.3	1.2	-0.7	-0.6	-0.6	0.6	-0.8	-0.3	-0.0	-1.2	-0.4	-0.3	0.1	-0.2
Hair Pigment	0.0	1.1	4.2	-0.1	1.1	-0.6	-0.2	1.1	0.0	2.0	0.3	-1.3	0.6	-0.7	-1.9	0.1	1.9	0.2	1.7	-0.2	-1.0	0.8

Hub : Genes

PGD

Models

Trait associations