Best TWAS P=4.04e-09 · Best GWAS P=9.88e-08 conditioned to 0.711
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | RMI1 | 0.12 | 0.11 | enet | 15 | 0.14 | 1.3e-06 | -5.3 | -5.9 | 4.0e-09 | 0.93 | 0.01 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Stomach Adenocarcinoma | RMI1 | 0.05 | 0.06 | enet | 5 | 0.06 | 2.2e-05 | -5.1 | -5.6 | 1.7e-08 | 0.85 | 0.01 | 0.95 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RMI1 | 0.02 | 0.02 | blup | 31 | 0.01 | 8.8e-04 | 5.0 | -5.6 | 2.3e-08 | 0.77 | 0.02 | 0.87 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RMI1 | 0.03 | 0.03 | lasso | 4 | 0.04 | 4.1e-05 | 5.0 | -5.6 | 2.8e-08 | 0.82 | 0.02 | 0.92 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | RMI1 | 0.05 | 0.04 | lasso | 2 | 0.00 | 1.8e-01 | -5.3 | -5.3 | 1.0e-07 | 1.00 | 0.01 | 0.74 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RMI1 | 0.03 | 0.03 | blup | 31 | 0.01 | 1.2e-02 | 5.0 | -5.3 | 1.4e-07 | 0.65 | 0.02 | 0.90 | FALSE |