[Hub]/) : Traits : Comparative height size at age 10 :

chr9:35,074,917-36,597,142

Best TWAS P=3.07e-10 · Best GWAS P=8.46e-08 conditioned to 0.3

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SPAG8 0.13 0.04 enet 14 0.06 8.7e-06 -5.3 -5.4 6.6e-08 0.28 0.01 0.99 FALSE
2 GTEx Adrenal Gland HRCT1 0.23 0.19 lasso 3 0.15 6.4e-06 -4.5 -5.3 1.1e-07 0.42 0.06 0.89 TRUE
3 GTEx Artery Aorta RP11-112J3.16 0.20 0.09 lasso 5 0.11 1.6e-06 -5.0 -5.2 1.7e-07 0.33 0.03 0.96 FALSE
4 GTEx Artery Tibial RP11-112J3.16 0.07 0.05 lasso 3 0.05 9.1e-05 -4.2 -5.1 2.8e-07 0.33 0.04 0.95 FALSE
5 GTEx Heart Atrial Appendage RP11-112J3.16 0.15 0.02 lasso 5 0.05 1.9e-03 -5.0 -6.2 4.9e-10 0.51 0.04 0.64 FALSE
6 GTEx Lung HRCT1 0.08 0.01 enet 14 0.02 5.5e-03 -5.1 -5.9 3.7e-09 0.42 0.04 0.59 TRUE
7 GTEx Muscle Skeletal RP11-112J3.16 0.06 0.07 lasso 3 0.05 2.7e-05 -5.0 -5.1 3.1e-07 0.35 0.04 0.96 FALSE
8 GTEx Nerve Tibial SPAG8 0.13 0.09 lasso 4 0.08 5.2e-06 -5.3 -5.6 2.5e-08 0.33 0.01 0.99 FALSE
9 GTEx Skin Sun Exposed Lower leg TMEM8B 0.19 0.16 enet 29 0.19 6.5e-16 -4.7 -5.5 3.5e-08 0.38 0.14 0.85 FALSE
10 GTEx Testis TMEM8B 0.16 0.19 lasso 2 0.16 1.2e-07 -5.3 -5.3 1.2e-07 0.33 0.01 0.99 FALSE
11 YFS Blood SPAG8 0.04 0.03 lasso 7 0.02 2.6e-08 -5.1 -5.2 1.8e-07 0.32 0.02 0.98 FALSE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma RGP1 0.07 0.00 lasso 5 0.03 8.1e-04 -2.5 -6.2 5.6e-10 0.19 0.01 0.27 TRUE
13 The Cancer Genome Atlas Rectum Adenocarcinoma HRCT1 0.26 0.03 blup 49 0.11 1.5e-03 -4.9 -6.3 3.1e-10 0.59 0.01 0.15 TRUE