[Hub]/) : Traits : Comparative height size at age 10 :

chr10:123,438,113-124,889,817

Best TWAS P=7.77e-14 · Best GWAS P=1.14e-13 conditioned to 0.000844

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 6.8 -6.9 6.9e-12 0.21 0.26 0.64 FALSE
2 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 6.8 -5.9 4.4e-09 0.18 0.30 0.70 FALSE
3 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -5.5 -5.9 3.1e-09 0.30 0.08 0.82 FALSE
4 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 6.7 -6.8 1.3e-11 0.32 0.21 0.78 TRUE
5 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -7.2 -7.2 7.2e-13 0.29 0.03 0.97 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma ARMS2 0.04 0.02 lasso 3 0.01 2.7e-02 -2.4 -5.2 1.8e-07 0.24 0.02 0.94 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 6.8 -6.8 1.2e-11 0.21 0.24 0.70 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARMS2 0.23 0.20 lasso 2 0.21 7.0e-09 -7.2 -7.5 7.8e-14 0.55 0.01 0.99 TRUE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 6.7 -6.1 1.2e-09 0.19 0.05 0.49 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -7.2 -7.1 1.4e-12 0.31 0.02 0.97 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 6.7 -6.7 2.2e-11 0.21 0.39 0.61 FALSE