Best TWAS P=5.49e-09 · Best GWAS P=3.38e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | ZNF143 | 0.27 | 0.13 | lasso | 5 | 0.10 | 0.00078 | -5.6 | -5.4 | 6.5e-08 | -0.83 | 0.02 | 0.86 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF143 | 0.02 | 0.02 | lasso | 2 | 0.02 | 0.00453 | 6.0 | -5.8 | 5.5e-09 | -0.96 | 0.01 | 0.91 | TRUE |