TWAS
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Comparative height size at age 10
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chr11:13,608,389-15,589,019
Best TWAS P=8.47e-11 · Best GWAS P=1.66e-11 conditioned to 2.81e-08
13.5M
14M
14.5M
15M
15.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Testis
RRAS2
0.18
0.13
enet
19
0.15
2.7e-07
-5.0
6.5
8.5e-11
0.20
0.27
0.73
TRUE
2
GTEx
Heart Atrial Appendage
PDE3B
0.17
0.05
lasso
9
0.04
5.3e-03
-4.8
-5.4
6.5e-08
-0.15
0.16
0.10
FALSE
4
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
RRAS2
0.13
0.01
blup
11
0.05
4.0e-03
5.8
5.4
6.5e-08
0.46
0.00
0.93
FALSE
1
GTEx
Brain Cerebellum
COPB1
0.16
0.09
lasso
8
0.06
9.3e-03
5.6
-5.2
1.8e-07
-0.22
0.23
0.10
FALSE