TWAS hub - ZNF143

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.1500	0.0650	8.0e-03	-0.008	NA	0.015	NA	-0.001	6.5e-01	NA	1.2e-01	NA	3.4e-01
2	GTEx	Brain Cortex	0.2700	0.1050	3.9e-03	0.129	NA	0.023	NA	0.105	2.1e-04	NA	7.8e-02	NA	7.8e-04
3	GTEx	Esophagus Mucosa	0.1550	0.0610	2.5e-03	0.052	NA	0.043	NA	0.047	2.3e-04	NA	6.9e-04	NA	4.1e-04
4	GTEx	Lung	0.0875	0.0339	2.4e-03	0.107	NA	0.102	NA	0.103	1.4e-08	NA	3.5e-08	NA	3.0e-08
5	GTEx	Nerve Tibial	0.0794	0.0349	9.2e-03	0.070	NA	0.064	NA	0.038	1.0e-05	NA	2.5e-05	NA	1.0e-03
6	GTEx	Spleen	0.4660	0.0840	2.4e-07	0.310	NA	0.254	NA	0.293	1.1e-08	NA	3.4e-07	NA	3.2e-08
7	GTEx	Thyroid	0.3250	0.0600	4.3e-11	0.212	NA	0.169	NA	0.201	3.5e-16	NA	5.9e-13	NA	2.6e-15
8	METSIM	Adipose	0.0967	0.0259	5.3e-10	0.099	0.082	0.093	0.099	0.090	1.2e-14	2.4e-12	9.5e-14	1.2e-14	2.4e-13
9	NTR	Blood	0.0244	0.0095	1.2e-03	0.015	0.000	0.010	0.012	0.013	7.1e-06	2.5e-01	1.9e-04	8.9e-05	2.9e-05
10	YFS	Blood	0.1727	0.0287	0.0e+00	0.182	0.181	0.176	0.185	0.179	3.5e-57	9.5e-57	3.9e-55	4.0e-58	3.3e-56
11	TCGA	Brain Lower Grade Glioma	0.0244	0.0157	3.7e-03	0.022	0.008	0.002	NA	0.017	1.5e-03	4.1e-02	1.7e-01	NA	4.5e-03
12	TCGA	Testicular Germ Cell Tumors	0.1920	0.1000	1.9e-03	0.037	0.081	0.084	NA	0.068	1.9e-02	8.1e-04	6.9e-04	NA	2.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Health satisfaction	5.6	7.3	10.7	3.3	1.9	2.9	2.5	3.0	2.6	2.5	2.9	2.6	2.3	2.4	3.3
Medication: Simvastatin	5.2	7.6	10.1	2.8	2.5	2.4	2.8	2.3	3.2	3.0	3.1	2.7	2.7	3.0	2.4
Gout (self-reported)	5.1	7.0	13.2	-2.5	-2.2	-3.6	-2.5	-2.5	-2.6	-2.6	-2.7	-2.3	-2.5	-2.6	-2.9
Worry too long after embarrassment	5.1	8.6	18.3	4.0	3.8	1.6	1.9	3.4	2.3	1.8	2.4	1.9	1.9	4.3	3.8
Frequency of tiredness / lethargy in last 2 weeks	4.8	7.9	13.1	3.4	1.8	2.9	2.8	3.2	2.9	2.7	3.1	2.4	2.7	1.4	3.6
Falls in the last year	4.4	5.9	7.9	2.8	2.5	2.5	2.1	2.3	2.6	2.1	2.6	2.2	2.2	2.2	2.8
Commuting to job workplace: Cycle	4.4	5.3	10.4	2.8	0.2	1.8	2.7	1.6	2.9	2.4	2.4	3.2	2.6	1.4	1.9
Guilty feelings	4.0	6.0	11.8	2.6	1.8	2.6	2.1	3.4	2.5	2.2	2.2	2.5	2.0	2.1	2.7
Medication: Cholesterol lowering	3.9	6.1	9.9	2.5	1.2	2.0	2.7	2.5	3.1	2.8	3.0	2.5	2.7	1.9	1.9
Medication for cholesterol, blood pressure or diabetes	3.7	6.2	10.4	-2.6	-0.6	-1.8	-2.9	-2.6	-3.2	-3.0	-3.1	-2.8	-2.9	-1.5	-1.2
Waist Hip Ratio (WHR)	3.0	13.7	28.2	4.4	3.4	3.8	2.8	4.6	3.0	3.0	3.5	2.9	2.9	3.8	5.3
Neuroticism score	3.0	6.2	12.5	3.5	2.9	2.1	1.9	3.2	2.3	1.8	2.3	2.0	1.8	2.5	2.8
Number of live births	3.0	4.2	7.9	1.0	0.9	2.8	2.4	2.1	2.3	2.3	2.3	1.8	2.4	1.4	2.0
Chronotype (morning person)	2.9	6.7	10.5	2.0	-1.6	2.8	3.2	2.8	2.9	3.2	2.9	3.1	3.2	-0.2	-0.5
Myopia	2.9	4.2	5.6	2.2	0.8	2.4	2.3	2.3	2.1	2.1	2.3	1.9	2.3	1.3	2.1
Neuroticism (2016)	2.6	3.7	8.7	2.7	3.0	1.9	0.8	1.5	1.4	0.5	1.5	0.8	0.9	2.8	3.0
Prospective memory result	2.6	3.2	5.0	-1.5	-0.2	-1.7	-2.2	-2.0	-2.0	-2.2	-2.0	-2.1	-2.2	-1.0	-1.3
Sensitivity / hurt feelings	2.5	4.3	9.6	3.1	1.8	1.3	1.8	2.6	2.1	1.8	2.2	1.9	1.9	2.0	1.8
Number of full brothers	2.5	3.2	5.0	-2.2	0.9	-2.2	-2.0	-1.9	-2.1	-1.9	-2.2	-1.9	-1.9	-0.1	0.2
Number of operations (self-reported)	2.5	3.7	7.4	2.4	2.6	1.5	1.4	1.8	1.5	1.5	1.6	1.6	1.4	2.4	2.7
Average weekly beer plus cider intake	2.5	3.6	5.9	-2.0	-0.1	-1.5	-2.2	-2.4	-2.4	-2.3	-2.2	-1.9	-2.3	-0.8	-0.7
Migraine (self-reported)	2.4	3.0	6.3	1.7	2.5	2.0	1.3	0.9	1.5	1.2	1.6	1.7	1.4	2.5	1.6
Stomach or abdominal pain in last month	2.3	2.9	7.6	1.6	1.4	2.3	1.4	2.8	1.3	1.4	1.5	1.2	1.3	2.1	1.4
Neuroticism (Nagel 2018)	2.1	5.0	11.0	3.1	2.1	2.2	1.7	3.3	1.9	1.8	2.1	2.2	1.6	1.4	2.6
Alcohol drinker status: Previous	2.1	2.4	3.9	1.5	0.6	1.8	1.6	1.6	1.6	1.6	2.0	0.9	1.8	1.6	1.5
Mean Putamen Volume	2.0	2.3	4.2	-2.0	-1.0	-1.8	-1.2	-2.0	-1.3	-1.2	-1.4	-0.9	-1.3	-1.4	-2.0
Current tobacco smoking	2.0	3.3	6.8	-1.3	1.5	-2.0	-2.2	-2.6	-2.0	-2.0	-1.9	-1.9	-2.2	-0.6	-0.4
Alcohol usually taken with meals	2.0	3.3	6.7	2.6	-1.5	1.9	1.8	2.1	2.0	1.9	1.9	2.0	1.7	-0.7	-0.0
Family relationship satisfaction	2.0	2.4	3.7	0.7	0.4	1.5	1.9	1.6	1.5	1.9	1.6	1.8	1.7	1.7	1.6
Neuroticism	1.9	4.5	10.0	3.2	2.8	1.7	1.3	2.8	1.7	1.3	1.7	1.5	1.3	1.9	3.1
Breastfed as a baby	1.9	2.4	5.2	-0.9	-1.6	-1.5	-1.4	-1.3	-1.5	-1.4	-1.4	-1.6	-1.4	-2.3	-1.7
Medication: Allopurinol	1.9	2.5	6.9	-1.7	-1.5	-2.6	-1.3	-1.8	-1.6	-1.3	-1.5	-1.2	-1.5	-1.3	-1.1
Chest pain or discomfort	1.9	2.8	5.5	2.4	0.4	2.0	1.5	2.3	1.6	1.4	1.6	2.1	1.2	1.2	1.5
Medication: Aspirin	1.9	2.5	9.2	0.9	1.8	1.4	1.3	1.3	1.6	1.4	1.4	1.3	1.1	1.2	3.0
Verbal and Numeric Reasoning (VNR)	1.8	4.4	8.5	2.9	0.7	2.5	1.9	2.9	2.1	1.9	2.3	1.6	2.0	1.4	1.8
Age when periods started (menarche)	1.8	4.4	7.2	-2.7	-1.6	-1.8	-1.9	-2.6	-2.2	-2.0	-2.3	-2.0	-1.9	-1.8	-2.1
Smoking status: Current	1.7	2.7	5.4	-1.2	1.3	-1.8	-2.0	-2.3	-1.7	-1.8	-1.7	-1.7	-2.0	-0.6	-0.5
Pain experienced in last month	1.7	2.8	8.8	-1.5	-2.2	-1.4	-1.1	-0.9	-1.2	-1.2	-1.4	-0.8	-0.8	-2.7	-3.0
Impedance of leg (right)	1.6	7.7	18.1	3.6	3.4	2.7	1.8	2.9	1.9	2.1	2.0	1.3	1.7	4.3	3.7
Allergy	1.6	3.7	9.3	-2.2	1.3	-2.5	-1.7	-3.0	-1.8	-1.9	-1.8	-1.3	-1.6	2.0	-1.2
Illnesses of mother	1.6	2.0	4.7	-0.7	-2.2	-1.4	-0.8	-2.0	-1.0	-0.8	-1.1	-0.7	-0.7	-2.1	-1.8
Irritable Bowel Disease (IBD)	1.5	3.6	6.5	1.9	0.6	2.3	1.8	2.5	1.8	2.0	2.0	2.3	1.8	1.8	1.2
Diabetes (mother)	1.5	1.9	5.6	1.0	0.7	1.6	1.2	2.2	1.2	1.2	1.3	1.2	1.2	0.4	2.4
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	6.9	0.7	2.4	1.2	0.6	1.5	0.6	0.7	0.5	0.4	0.6	2.6	1.8
Chronic bronchitis/emphysema (father)	1.5	1.8	6.0	0.6	1.8	0.9	0.8	0.8	0.6	0.7	1.1	1.2	0.9	2.4	2.5
Worrier / anxious feelings	1.5	2.9	11.3	1.8	2.9	0.7	0.6	2.3	0.9	0.5	0.9	0.4	0.5	3.4	1.8
Medication: Ibuprofen	1.5	1.8	3.0	0.9	-0.8	1.5	1.6	1.3	1.5	1.6	1.6	1.7	1.6	0.0	1.1
Ever used hormone-replacement therapy (HRT)	1.4	1.8	8.5	-0.0	2.4	1.0	0.5	0.3	0.2	0.6	0.5	0.6	0.6	2.9	2.0
Mouth/teeth dental problems	1.4	2.2	5.1	-1.4	-2.3	-1.3	-0.9	-0.9	-1.2	-0.8	-1.1	-1.9	-0.9	-1.8	-2.2
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	3.0	0.7	-0.7	1.5	1.7	1.1	1.5	1.6	1.6	1.6	1.6	0.2	0.8
Tense / ‘highly strung’	1.4	2.3	8.8	1.4	3.0	0.9	0.8	2.2	1.1	0.9	0.9	0.9	0.8	1.9	1.6
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	4.5	1.3	1.8	0.4	0.9	1.5	1.2	0.9	1.3	1.4	0.8	1.5	2.1
Headache pain in last month	1.4	2.4	9.3	-0.3	3.0	1.2	0.5	0.1	0.4	0.5	0.7	0.9	0.4	2.8	2.9
Comparative height size at age 10	1.4	7.6	34.0	0.6	-5.4	-0.9	-1.5	-1.1	-1.1	-1.4	-1.5	-1.9	-1.6	-5.8	-3.4
Wears glasses or contact lenses	1.4	1.6	9.2	1.2	1.9	0.6	0.7	0.8	0.7	0.7	1.0	0.4	0.7	3.0	0.9
Alzheimer’s Disease (including proxy)	1.3	1.8	8.2	0.6	2.6	0.4	0.6	0.5	0.6	0.6	0.6	0.7	0.4	2.9	2.1
Ulcerative Colitis (UC)	1.3	2.5	5.1	1.2	-0.0	2.1	1.6	2.3	1.6	1.9	1.8	1.8	1.7	0.2	0.5
Hayfever, allergic rhinitis or eczema	1.3	2.9	8.9	2.3	-1.4	1.7	1.3	3.0	1.5	1.5	1.4	0.7	1.3	-2.1	0.6
High blood pressure (mother)	1.3	1.8	8.2	-0.7	2.9	-0.5	-1.0	0.1	-0.9	-1.1	-0.7	-1.1	-1.2	2.3	0.7
Nervous feelings	1.3	2.4	10.0	1.9	3.2	0.5	0.4	1.9	0.7	0.2	0.7	0.5	0.2	2.5	1.9
Financial difficulties in last 2 years	1.3	1.7	2.5	-1.5	0.5	-1.3	-1.4	-1.6	-1.4	-1.6	-1.4	-1.2	-1.4	-0.8	1.3
Pain all over the body in last month	1.3	1.4	4.8	-1.1	-1.4	-1.1	-1.1	-0.4	-0.7	-1.0	-1.0	-1.3	-1.1	-2.2	-0.9
Hair/balding pattern: Pattern 3	1.3	1.9	6.0	-0.3	-2.3	-1.1	-0.7	-1.5	-0.6	-1.0	-0.9	-0.5	-0.5	-2.2	-2.4
Heart disease (mother)	1.3	1.6	7.5	0.2	1.6	1.1	0.6	1.6	0.8	0.7	0.7	1.2	0.6	1.3	2.7
Age at last live birth	1.3	1.8	8.6	0.9	-2.9	0.1	0.5	1.5	0.5	0.5	0.3	-0.1	0.4	-2.4	-1.9
Commuting to job workplace: Public transport	1.3	1.5	3.1	-0.9	0.4	-0.9	-1.5	-1.8	-1.6	-1.7	-1.5	-1.1	-1.5	0.3	0.2
Worry (Nagel 2018)	1.2	2.6	8.0	2.1	2.8	0.9	0.5	2.5	1.0	0.5	0.9	0.6	0.5	2.2	1.9
Crohns Disease (2017)	1.2	2.7	8.6	2.0	1.4	1.5	1.2	1.7	1.2	1.3	1.4	1.7	1.2	2.9	1.4
LDL Cholesterol	1.2	1.9	4.7	0.2	-2.2	1.5	1.7	0.1	1.4	1.7	1.3	1.6	1.7	-0.9	-0.8
Hearing difficulty/problems: Yes	1.2	1.9	4.2	-1.4	-0.3	-1.4	-1.4	-2.1	-1.6	-1.4	-1.5	-1.4	-1.3	-0.8	-1.2
Impedance of leg (left)	1.2	5.7	18.7	2.8	3.4	2.2	1.2	2.2	1.2	1.6	1.4	0.9	1.2	4.3	3.4
Hair/balding pattern: Pattern 2	1.2	1.5	7.1	-0.1	2.7	-0.4	-0.6	0.3	-0.7	-0.4	-0.4	-0.9	-1.0	2.0	2.0
Trunk fat-free mass	1.2	7.0	44.8	-1.1	-5.2	-0.5	-0.8	-0.8	-0.3	-0.8	-0.9	-0.7	-0.6	-6.7	-2.8
Trunk predicted mass	1.2	6.7	43.3	-1.0	-5.1	-0.4	-0.7	-0.7	-0.3	-0.7	-0.9	-0.6	-0.5	-6.6	-2.7
Qualifications: College or University degree	1.2	3.9	18.1	1.7	3.4	1.1	0.5	1.5	0.6	0.5	0.7	0.7	0.3	4.3	3.0
Medication: Blood pressure	1.2	2.1	3.9	1.7	0.4	0.6	1.7	1.6	1.9	1.7	2.0	1.5	1.6	1.1	0.2
Friendships satisfaction	1.2	1.5	4.0	1.1	1.5	1.4	1.0	0.9	0.9	1.0	1.0	0.5	0.7	1.8	2.0
Medication: Aspirin	1.2	1.6	6.8	0.6	1.9	1.0	0.8	0.7	1.0	0.9	0.9	0.6	0.6	1.6	2.6
Bipolar Disorder (2011)	1.1	1.0	5.0	-0.3	-1.2	-0.1	-0.3	0.8	-0.0	-0.3	-0.4	-0.1	-0.2	-2.2	-2.2
HbA1C	1.1	1.2	5.5	1.8	1.5	0.3	0.3	-0.5	0.5	0.2	0.7	-0.1	0.3	2.4	1.6
Blood Platelet Count	1.1	12.5	82.1	-1.4	1.9	-3.3	-2.6	-9.1	-3.0	-2.5	-2.6	-2.6	-2.8	2.7	-0.8
Allergy or Eczema	1.1	2.9	11.4	2.2	-1.5	1.6	1.2	3.4	1.5	1.4	1.4	0.3	1.3	-2.0	0.2
Lung FEV1/FVC ratio	1.1	5.4	14.0	-1.7	-1.4	-3.7	-2.5	-2.5	-2.3	-2.8	-2.5	-2.0	-2.4	-1.7	-0.9
Ever had hysterectomy (womb removed)	1.1	1.2	2.8	0.3	0.5	1.5	1.2	-0.1	1.1	1.0	1.0	1.7	1.2	1.3	1.3
Hand grip strength (right)	1.1	2.9	6.0	-1.2	-1.4	-1.8	-1.6	-2.5	-1.4	-1.7	-2.0	-1.7	-1.7	-1.6	-1.5
Medication: Lansoprazole	1.1	1.2	3.3	1.2	0.6	1.1	1.0	1.8	1.0	1.0	1.2	1.2	0.8	1.0	1.1
Age at first live birth	1.1	1.9	9.1	1.5	-3.0	0.8	0.7	1.8	0.6	0.6	0.7	0.4	0.5	-1.5	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	6.1	1.7	-2.5	0.7	1.6	1.2	1.6	1.4	1.4	1.6	1.6	-1.5	-1.0
Whole body fat-free mass	1.1	6.1	38.8	-1.0	-4.9	-0.4	-0.6	-0.6	-0.2	-0.6	-0.8	-0.5	-0.5	-6.2	-2.5
Long-standing illness, disability or infirmity	1.1	1.7	3.2	1.2	1.1	1.5	1.1	1.8	1.1	1.2	1.4	1.2	1.3	1.0	1.4
Whole body water mass	1.1	6.1	39.6	-1.0	-5.0	-0.3	-0.5	-0.5	-0.1	-0.6	-0.7	-0.4	-0.4	-6.3	-2.5
Fractured/broken bones in last 5 years	1.1	1.4	5.3	0.7	2.3	-0.1	0.2	-0.6	0.5	0.3	0.5	0.3	0.2	2.2	2.3
Impedance of whole body	1.1	5.8	23.1	2.6	4.1	1.5	1.0	1.9	0.9	1.2	1.2	0.7	0.9	4.8	3.3
Hand grip strength (left)	1.0	2.8	5.0	-1.0	-1.2	-1.8	-1.6	-2.2	-1.5	-1.6	-1.9	-1.8	-1.7	-1.2	-1.9
Alcohol intake versus 10 years previously	1.0	1.5	6.3	-0.8	-2.1	-0.5	-0.4	-1.2	-0.5	-0.4	-0.6	-0.3	-0.1	-2.5	-2.0
Asthma	1.0	1.9	4.4	1.5	-0.5	2.1	1.3	1.4	1.2	1.2	1.5	1.7	1.3	-0.4	1.5
Glaucoma (self-reported)	1.0	1.2	2.4	0.0	-1.3	-0.4	-1.2	0.6	-1.2	-1.4	-0.9	-1.2	-1.2	-1.6	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.2	-1.3	0.2	-1.5	-1.2	-0.8	-1.2	-1.2	-1.4	-1.2	-1.1	0.7	0.5
Mouth/teeth dental problems: Loose teeth	1.0	1.1	2.2	0.6	0.3	1.2	1.3	1.0	1.1	1.2	1.4	1.2	1.5	0.6	0.5
Medication for pain relief, constipation, heartburn	1.0	1.7	6.8	-0.1	-1.1	-1.6	-1.3	-0.8	-1.1	-1.2	-1.3	-1.0	-1.2	-1.2	-2.6
Illnesses of father: Heart disease	1.0	1.4	5.7	0.7	2.4	1.3	0.5	0.9	0.9	0.3	0.5	0.6	0.6	1.9	1.5
Leg fat-free mass (right)	1.0	5.2	30.2	-1.4	-4.3	-0.9	-0.8	-0.9	-0.6	-0.9	-0.9	-0.6	-0.7	-5.5	-2.5
Mood swings	1.0	1.8	3.1	1.1	0.7	1.7	1.6	1.3	1.5	1.6	1.6	1.8	1.4	0.5	0.5
Loneliness, isolation	1.0	1.4	7.7	0.5	-1.7	-0.5	-0.8	-0.4	-0.8	-0.8	-0.7	-1.3	-0.9	-2.8	-1.0
Leg predicted mass (right)	1.0	5.2	29.8	-1.5	-4.2	-1.0	-0.9	-1.0	-0.7	-1.0	-1.0	-0.6	-0.8	-5.5	-2.5
HDL Cholesterol	0.9	1.4	7.2	0.1	2.7	-0.3	-0.6	-0.3	-0.4	-0.6	-0.4	-0.6	-0.3	1.7	2.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.3	6.5	1.6	2.5	0.1	0.0	1.1	0.5	-0.1	0.4	-0.3	0.0	1.3	1.9
Illnesses of siblings	0.9	1.2	7.0	0.4	-2.6	0.0	0.3	-0.8	-0.0	0.4	0.4	0.4	0.4	-1.5	-1.9
Depression (self-reported)	0.9	1.1	4.5	0.9	2.1	-0.0	-0.3	0.6	-0.1	-0.2	0.0	-0.3	-0.4	1.9	2.0
Medication: Paracetamol	0.9	1.5	3.9	-1.0	2.0	-0.7	-1.0	-1.1	-1.0	-1.1	-0.8	-1.1	-0.9	1.7	1.6
Arm fat-free mass (right)	0.9	4.5	30.0	-0.3	-4.6	0.5	0.2	-0.0	0.5	0.2	-0.0	0.2	0.3	-5.5	-1.5
Arm predicted mass (right)	0.9	4.6	30.8	-0.2	-4.6	0.6	0.1	0.1	0.4	0.1	-0.1	0.2	0.2	-5.5	-1.5
Pulse rate, automated reading	0.9	3.0	10.2	1.9	2.8	1.2	0.5	1.3	0.9	0.5	1.1	0.3	0.5	3.2	2.9
Overall health rating	0.9	2.0	3.4	1.7	1.8	1.7	1.0	1.3	1.1	1.2	1.3	0.7	0.9	1.7	1.9
Medication: Paracetamol	0.9	1.3	2.3	-0.7	1.5	-0.6	-1.2	-0.9	-1.3	-1.5	-0.9	-1.4	-1.1	1.3	1.0
Illnesses of father: High blood pressure	0.9	1.1	2.7	-1.3	1.6	-0.4	-1.0	-0.9	-0.7	-1.2	-0.9	-1.3	-1.0	1.0	-0.7
Basal metabolic rate	0.9	5.2	35.0	-0.9	-4.5	-0.2	-0.5	-0.5	-0.1	-0.5	-0.6	-0.3	-0.4	-5.9	-2.2
Arm fat-free mass (left)	0.9	4.4	30.6	-0.4	-4.2	0.7	0.1	0.1	0.5	0.2	-0.1	0.2	0.2	-5.5	-1.6
Irritability	0.9	1.6	4.4	1.7	0.6	1.4	1.1	2.1	1.4	1.1	1.3	0.9	1.2	0.1	1.2
Supplements: Calcium	0.9	1.0	3.8	0.4	1.9	0.3	-0.3	0.6	-0.4	-0.1	-0.0	-0.4	-0.3	2.0	1.7
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	2.5	-1.1	1.6	-0.5	-1.1	-0.6	-1.1	-1.1	-1.1	-1.6	-1.0	0.7	0.2
Intelligence (Savage-Jansen 2018)	0.8	2.3	4.9	2.2	0.7	1.7	1.4	2.2	1.2	1.5	1.6	1.1	1.2	1.0	1.9
Alzheimer’s Disease (in mother)	0.8	0.9	4.7	1.0	2.0	0.4	0.2	0.4	0.5	0.3	0.4	0.3	0.2	2.2	1.0
Alzheimer’s Disease (in father)	0.8	0.9	2.6	0.3	0.7	1.2	1.0	0.8	0.8	0.9	0.9	0.9	0.8	0.8	1.6
Prostate Cancer	0.8	1.1	2.2	1.4	0.3	1.2	1.0	-0.1	0.9	1.2	1.3	1.2	0.9	1.5	0.9
Lung FVC	0.8	3.9	9.1	-1.9	1.8	-2.0	-1.9	-3.0	-1.8	-2.3	-1.8	-2.4	-2.0	1.1	-0.2
Severe depression (siblings)	0.8	0.9	1.5	-1.0	0.6	-0.6	-1.2	-0.9	-1.2	-1.2	-1.2	-1.0	-1.1	-0.2	-0.4
Leg fat-free mass (left)	0.8	4.3	28.5	-0.9	-4.1	-0.5	-0.4	-0.4	-0.1	-0.5	-0.5	-0.2	-0.3	-5.3	-2.1
Maternal smoking around birth	0.8	1.2	3.3	0.1	0.1	1.2	1.4	0.3	1.0	1.3	1.3	1.8	1.5	0.9	0.1
Fed-up feelings	0.8	1.5	4.9	2.2	0.5	1.3	1.3	0.1	1.3	1.4	1.5	1.3	1.1	0.7	0.5
Leg predicted mass (left)	0.8	4.3	28.7	-0.9	-4.1	-0.4	-0.4	-0.3	-0.1	-0.4	-0.5	-0.2	-0.3	-5.4	-2.0
Fluid intelligence score	0.8	1.7	5.0	2.2	-0.4	1.5	1.0	2.2	1.0	1.2	1.3	0.9	1.1	-0.1	0.9
Mouth/teeth dental problems: Dentures	0.8	1.3	2.0	1.4	1.4	1.3	0.9	0.5	1.1	0.9	1.0	1.4	0.9	1.4	1.3
Lung cancer (father)	0.8	1.0	3.0	-1.7	-0.0	-0.5	-0.8	-1.1	-1.0	-0.9	-1.0	-0.7	-0.9	0.7	-1.5
Shortness of breath walking on level ground	0.8	1.0	2.7	-0.1	1.6	-0.2	-1.2	0.2	-1.1	-1.3	-0.8	-0.9	-1.2	1.4	-0.0
Suffer from ‘nerves’	0.8	1.3	3.7	1.8	1.8	0.8	0.5	1.4	0.9	0.5	0.6	0.5	0.4	0.7	1.9
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	6.1	0.3	-1.9	0.5	0.6	0.5	0.4	0.6	0.4	0.2	0.6	-0.6	-2.5
Commuting to job workplace: Walk	0.8	0.8	1.5	0.6	-0.6	0.9	1.0	1.1	1.2	0.9	0.8	1.2	1.0	-0.7	0.5
Illnesses of father: None of the above (group 1)	0.8	1.0	5.2	0.2	-2.3	-0.8	-0.0	0.5	-0.4	0.3	-0.1	0.3	-0.1	-2.1	-0.9
Number of self-reported non-cancer illnesses	0.8	1.3	6.5	1.2	2.5	0.5	0.2	0.8	0.2	0.4	0.6	0.3	-0.0	1.9	1.8
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.6	1.6	-0.4	0.6	0.9	1.3	0.8	1.0	1.2	0.4	0.7	0.5	-1.2
Arm predicted mass (left)	0.8	4.0	28.8	-0.5	-4.0	0.4	-0.1	-0.2	0.3	-0.1	-0.3	-0.1	-0.0	-5.4	-1.5
Age at First Birth	0.7	1.0	5.1	-0.2	-2.3	0.0	0.3	0.7	-0.0	0.4	0.2	0.0	0.0	-1.4	-2.1
Fasting Glucose	0.7	0.8	1.8	0.5	-0.9	0.9	1.3	0.2	0.9	1.3	1.0	1.1	1.1	-0.7	0.1
Schizophrenia (2014)	0.7	1.6	3.6	0.0	-0.1	1.7	1.5	1.9	1.1	1.5	1.3	1.6	1.4	0.5	0.5
Systolic blood pressure, automated reading	0.7	2.1	6.1	-2.0	-0.1	-2.5	-1.3	-0.8	-1.3	-1.4	-1.4	-1.5	-1.7	0.9	-1.2
Average weekly fortified wine intake	0.7	0.9	3.4	1.1	1.1	0.0	0.5	0.2	0.7	0.4	0.6	0.2	0.3	1.7	1.9
Relative age voice broke	0.7	1.1	2.1	-1.3	1.4	-0.9	-1.0	-1.3	-1.4	-0.9	-1.0	-0.6	-0.9	1.3	-0.1
Time employed in main current job	0.7	0.8	2.5	1.3	1.6	0.8	0.5	1.0	0.4	0.7	0.7	0.4	0.3	1.5	0.6
Loud music exposure frequency	0.7	0.7	2.4	0.6	-1.6	-0.2	0.8	0.9	0.5	0.8	0.7	0.6	0.8	-1.3	-0.3
Blood clot in the leg (DVT)	0.7	1.0	2.3	-1.2	1.4	-0.4	-1.1	-0.5	-1.1	-1.0	-1.0	-1.5	-0.9	0.5	0.3
High blood pressure (siblings)	0.7	1.1	3.4	-1.3	1.8	-0.8	-1.1	-0.3	-1.0	-1.3	-1.1	-0.7	-1.0	0.4	0.3
Leg fat percentage (right)	0.7	2.5	6.0	1.4	0.5	1.9	1.4	2.3	1.5	1.6	1.5	1.5	1.4	-0.2	2.5
Breast cancer (self-reported)	0.7	0.8	2.6	-0.1	-1.2	-1.1	-0.4	-1.6	-0.5	-0.4	-0.5	-0.4	-0.4	-1.1	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	2.8	-1.0	1.4	-1.6	-1.0	-1.7	-0.9	-1.3	-0.9	-1.3	-1.0	1.5	-1.0
Ovarian Cancer	0.6	0.8	2.5	-0.5	1.2	-0.6	-0.8	-1.3	-0.6	-0.7	-0.6	-0.7	-0.9	-0.0	1.6
Coronary Artery Disease (CAD)	0.6	0.7	3.9	-2.0	0.3	-0.8	-0.5	-0.8	-0.7	-0.5	-0.9	0.2	-0.7	-0.8	-0.4
Triglycerides	0.6	1.0	2.8	-0.0	-1.7	1.0	1.3	0.9	1.0	1.2	1.1	0.6	1.1	-0.6	-0.7
Ulcerative Colitis	0.6	0.8	2.9	0.2	-0.4	1.0	0.8	1.7	0.8	1.1	0.8	1.2	0.8	-0.5	0.3
Systolic Blood Pressure	0.6	2.9	7.6	-2.6	0.4	-2.8	-1.5	-0.6	-1.6	-1.8	-1.6	-1.4	-1.9	1.1	-1.6
Type 2 Diabetes (T2D) (2018)	0.6	1.2	4.3	0.7	1.4	0.9	0.6	1.3	0.6	0.6	0.7	0.7	0.7	1.5	2.1
Number of treatments/medications taken	0.6	1.1	2.0	0.9	0.5	1.4	1.1	0.9	0.6	1.1	1.4	1.1	1.1	1.3	0.5
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.5	1.3	1.6	0.7	0.2	1.2	-0.1	0.1	0.5	0.4	0.2	1.4	0.5
Vitamin and mineral supplements	0.6	0.8	2.0	-0.6	-0.1	-1.2	-0.9	-0.9	-0.8	-1.2	-0.8	-0.7	-0.9	-0.3	-1.4
Number of incorrect matches in round	0.6	1.0	5.2	-0.2	-1.9	0.3	-0.3	1.1	-0.2	-0.4	-0.5	-0.8	-0.4	-2.3	-0.3
Had menopause	0.6	0.7	3.4	-0.2	1.8	0.5	0.1	0.7	-0.1	0.1	-0.1	0.0	0.2	1.4	1.5
Impedance of arm (right)	0.6	2.8	14.2	1.1	3.8	0.2	-0.1	1.0	-0.2	0.0	0.2	-0.3	-0.1	3.7	1.8
Hip circumference	0.6	2.7	19.0	-1.1	-3.0	-0.0	-0.3	-0.7	-0.2	-0.2	-0.5	-0.0	-0.3	-4.4	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	4.0	0.6	2.0	0.3	-0.2	0.5	-0.1	0.0	-0.0	-0.5	-0.4	1.3	1.4
Impedance of arm (left)	0.6	2.8	13.9	1.8	3.2	0.4	0.4	1.1	0.3	0.5	0.7	0.3	0.4	3.7	1.9
Exposure to tobacco smoke at home	0.6	0.7	2.8	-0.7	-1.7	1.2	0.6	0.8	0.3	0.4	0.5	0.5	0.6	-0.6	-0.9
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.5	1.3	1.1	1.1	0.2	0.7	0.4	-0.1	0.4	0.5	0.4	1.1	1.6
Leg pain on walking	0.6	0.8	1.4	0.2	-0.9	1.0	0.9	1.2	0.8	0.8	0.9	0.7	1.0	-0.3	-1.2
Knee pain experienced in last month	0.6	0.9	2.6	-0.2	1.6	-1.2	-0.9	-0.7	-1.0	-0.8	-0.7	-0.8	-0.9	1.5	-0.0
Medication for cholesterol	0.6	0.9	2.4	1.5	-1.1	0.9	0.7	1.1	0.9	0.5	0.6	0.7	0.9	-1.1	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.3	-1.5	0.4	-0.6	-1.0	-0.3	-0.9	-1.1	-0.9	-1.0	-0.8	-0.1	-0.0
Asthma (self-reported)	0.6	1.2	3.4	1.4	-0.4	1.8	0.9	1.1	0.9	0.9	1.2	1.3	0.9	-0.5	1.2
Osteoporosis (self-reported)	0.6	0.7	1.7	0.4	-0.7	1.3	0.9	0.2	0.7	0.8	0.9	1.3	0.9	-1.0	0.1
Hearing aid user	0.6	0.6	1.6	-0.2	0.2	1.0	1.0	-0.1	0.8	1.2	0.7	0.9	1.1	0.5	0.7
Eye problems/disorders: Glaucoma	0.6	0.7	3.4	0.3	-1.9	-0.5	-0.6	0.6	-0.6	-0.6	-0.4	-0.6	-0.6	-1.4	-0.8
Bipolar Disorder (2018)	0.5	0.8	3.0	-0.7	-0.8	-0.2	-0.8	-0.7	-0.8	-1.0	-1.0	-0.6	-0.8	-0.8	-1.7
Body Mass Index (BMI) (2010)	0.5	0.7	6.2	-0.3	-2.5	0.0	-0.0	-0.3	-0.2	-0.1	-0.2	0.1	-0.3	-1.2	-0.8
Crohns Disease (2012)	0.5	0.8	1.9	1.1	1.0	0.9	0.6	1.4	0.5	0.6	0.7	0.9	0.5	1.3	0.5
Blood Eosinophil Count	0.5	3.6	17.6	-0.6	-4.2	-0.8	-0.2	-0.9	-0.6	-0.3	-0.6	0.3	0.1	-3.7	-2.9
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.9	0.5	1.2	1.0	0.5	-0.1	0.4	0.4	0.5	0.3	0.4	0.8	1.4
Qualifications: CSEs or equivalent	0.5	0.6	2.8	-0.4	0.6	-1.5	-0.6	-1.7	-0.6	-0.6	-0.4	-0.5	-0.6	-0.4	-0.2
Weight	0.5	2.5	20.6	-0.4	-3.0	0.3	-0.1	0.4	0.2	-0.0	-0.1	0.2	-0.1	-4.5	-0.7
Pulse rate	0.5	0.8	4.7	0.4	1.8	0.1	-0.1	0.2	-0.1	-0.5	0.1	-0.2	-0.2	2.2	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	3.6	-1.1	-0.9	-1.9	-1.2	-1.3	-1.1	-1.6	-1.3	-1.3	-1.2	-1.4	-1.3
Standing height	0.5	4.5	28.9	1.0	-4.5	0.6	-0.0	0.9	0.4	0.1	-0.1	-0.2	0.0	-5.4	-1.6
Hair/balding pattern: Pattern 4	0.5	1.1	4.1	2.0	-0.7	1.4	0.5	1.5	1.1	0.4	1.0	0.6	0.6	-1.0	-0.4
Birth weight	0.5	1.2	4.4	1.4	2.1	0.6	-0.0	0.2	0.3	-0.1	0.2	-0.5	-0.2	1.7	2.0
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.1	0.2	0.5	1.0	1.0	0.5	0.8	1.0	0.9	1.0	1.0	0.7	-0.1
Had major operations	0.5	0.6	2.6	0.3	1.6	0.9	0.2	1.1	0.3	0.0	0.3	0.4	0.3	1.4	0.3
Supplements: Vitamin C	0.5	0.6	1.1	0.6	0.5	1.0	0.9	0.4	0.6	1.0	0.8	0.9	0.9	0.9	0.6
Average weekly red wine intake	0.5	0.8	2.4	0.8	-0.2	0.7	0.7	1.6	0.9	0.8	0.7	1.4	0.8	-0.4	0.6
Diabetes diagnosed by doctor	0.5	0.9	2.8	0.6	1.1	1.0	0.5	1.5	0.6	0.6	0.6	0.4	0.6	1.0	1.7
Qualifications: nursing, teaching	0.5	0.8	2.2	0.5	0.2	1.0	0.9	1.5	0.7	0.8	0.9	0.3	0.8	1.0	1.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.9	-0.1	1.4	-0.6	-1.2	-0.4	-0.9	-1.3	-1.1	-0.1	-1.2	-0.0	0.7
Back pain experienced in last month	0.5	0.8	2.3	0.2	1.4	-0.0	-0.9	0.0	-0.7	-0.6	-0.5	-1.5	-0.9	1.3	0.6
High cholesterol (Self-reported)	0.5	0.8	6.3	0.5	2.5	-0.2	0.1	-0.3	0.2	0.2	0.2	-0.2	0.0	1.7	0.6
Medication: Lisinopril	0.5	0.7	2.5	-0.1	0.4	-0.1	0.7	1.6	0.5	0.7	0.8	1.0	0.6	1.3	-0.4
Leg fat percentage (left)	0.5	1.6	5.2	0.8	0.6	1.6	1.0	1.9	1.1	1.2	1.1	1.2	1.0	-0.2	2.3
Ever depressed for a whole week	0.5	0.6	3.2	0.1	1.4	0.2	-0.1	-0.3	0.1	-0.1	-0.1	-0.0	0.0	1.8	1.3
Cholesterol lowering medication	0.5	0.7	4.0	-0.2	2.0	0.1	0.0	-0.5	-0.1	-0.0	0.0	-0.1	-0.2	1.9	0.8
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.8	0.8	1.0	1.3	0.3	1.1	0.3	0.5	0.5	0.0	0.3	1.3	0.3
Blood Red Count	0.4	3.9	14.5	-1.6	-3.8	0.3	0.0	-3.7	-0.0	1.2	-0.6	0.6	-0.1	-3.4	-1.6
Height	0.4	7.5	22.9	2.5	-4.5	2.9	1.8	3.3	2.2	1.9	1.8	1.4	1.8	-4.8	-0.6
Respiratory disease	0.4	0.8	2.7	1.1	-1.7	1.2	0.2	1.2	-0.2	0.2	0.5	0.3	0.2	-1.6	-0.1
Tanning	0.4	4.4	14.7	-1.4	0.3	-2.8	-2.0	-3.8	-2.3	-2.1	-1.9	-2.2	-2.0	1.2	-0.1
Medication: Co-codamol	0.4	0.5	1.1	0.1	0.4	-0.6	-0.9	-0.5	-0.9	-1.0	-0.8	-0.8	-1.1	-0.3	-0.0
Diabetes (father)	0.4	0.5	2.7	0.3	1.6	0.7	-0.2	-0.3	0.0	-0.4	0.0	-0.5	-0.1	1.0	1.1
Townsend deprivation index at recruitment	0.4	0.5	2.8	-1.1	0.4	-0.5	-0.4	-1.7	-0.7	-0.2	-0.4	0.0	-0.4	-0.3	0.8
Diabetes (self-reported)	0.4	0.6	3.1	0.1	1.3	0.3	-0.0	0.5	0.0	-0.1	-0.0	-0.2	-0.1	1.3	1.8
Noisy workplace	0.4	0.5	1.8	-0.0	-1.3	0.6	0.7	0.1	0.7	0.6	0.5	0.5	0.7	-1.1	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.3	1.5	0.6	1.2	0.7	0.7	0.7	0.4	0.9	0.6	0.6	1.4	1.0
Peak expiratory flow (PEF)	0.4	0.9	3.0	0.0	-0.3	-1.1	-0.9	-1.7	-0.8	-1.0	-0.9	-0.8	-0.9	-1.0	0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	3.2	-1.8	0.2	-0.6	-0.6	-0.8	-0.7	-0.4	-0.7	-0.1	-0.7	-1.1	-0.8
Eye problems/disorders: None of the above	0.4	0.4	1.3	0.3	-1.2	-0.3	0.8	-0.7	0.6	0.6	0.5	0.2	0.8	-0.8	-0.2
Leg fat mass (right)	0.4	1.7	4.5	0.8	-1.0	1.5	0.9	1.7	1.2	1.1	1.0	1.1	1.0	-2.1	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.7	-0.5	-1.3	-0.5	-0.1	-0.6	-0.1	-0.1	-0.1	-0.2	-0.1	-0.9	-1.3
Ever taken oral contraceptive pill	0.4	0.5	1.3	0.6	1.0	0.4	0.5	-0.2	0.4	0.7	0.7	0.3	0.6	1.1	0.9
Supplements: Fish oil (including cod liver oil)	0.4	0.5	3.0	0.0	-1.7	0.6	0.5	0.5	0.2	0.5	0.4	0.3	0.7	-0.8	-0.5
Risk taking	0.4	0.6	1.6	0.1	0.5	1.1	0.7	1.3	0.7	0.7	0.7	0.6	0.8	0.1	1.2
Diastolic blood pressure, automated reading	0.4	1.4	5.0	-1.6	0.2	-2.2	-0.9	-1.5	-0.9	-1.0	-1.0	-1.1	-1.3	0.0	-0.6
Basal cell carcinoma (self-reported)	0.4	0.5	2.6	0.3	1.6	0.3	-0.0	-0.1	0.2	-0.2	-0.1	0.6	0.0	1.5	0.6
Depressed Affect (Nagel 2018)	0.3	0.6	2.1	1.5	0.3	1.0	0.5	0.6	0.5	0.6	0.7	0.7	0.3	-1.0	0.4
Schizophrenia (2018)	0.3	0.6	1.9	-0.4	0.8	1.1	0.7	1.4	0.4	0.8	0.6	0.8	0.7	1.0	0.2
Schizophrenia vs Biploar Disorder	0.3	0.4	2.8	-0.0	-1.7	0.2	0.6	0.4	-0.1	0.6	0.7	0.6	0.7	0.0	-0.5
Lupus	0.3	0.5	2.0	0.4	0.2	1.0	0.4	1.4	0.5	0.5	0.5	0.5	0.5	0.6	0.8
Rheumatoid Arthritis	0.3	0.4	1.7	-0.5	-1.1	0.2	0.2	0.4	0.0	0.3	0.1	0.1	0.2	-1.3	-1.3
BMI	0.3	2.0	9.1	-0.1	-2.7	0.9	0.8	1.0	0.8	0.9	0.6	1.3	0.9	-3.0	0.2
Smoking Status	0.3	0.6	1.7	-0.9	0.8	-1.0	-0.7	-1.3	-0.9	-0.7	-0.8	-0.6	-0.6	0.4	0.0
Hypothyroidism (self reported)	0.3	0.6	2.6	-1.6	-0.4	-0.5	-0.4	-0.7	-0.4	-0.2	-0.6	0.3	-0.6	-1.1	-1.2
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.7	0.3	-0.4	-0.8	-0.6	-0.3	-0.5	-0.7	-0.4	-0.8	-0.6	-0.8	-0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	0.1	0.9	-0.4	-0.6	0.4	-0.3	-0.7	-0.5	-0.9	-0.5	0.7	0.1
Trunk fat percentage	0.3	1.2	4.8	0.8	1.2	1.2	0.7	1.5	0.8	0.9	0.9	0.9	0.7	0.4	2.2
Serious illness, injury or assault to yourself	0.3	0.4	0.9	-0.8	0.2	-0.4	-0.8	-1.0	-0.7	-0.6	-0.7	-0.3	-0.8	0.0	0.1
Hearing difficulty/problems with background noise	0.3	0.4	1.0	0.1	0.7	-1.0	-0.6	-1.0	-0.6	-0.6	-0.5	-0.9	-0.7	0.4	0.3
Had other major operations	0.3	0.3	1.2	0.8	1.0	0.2	-0.2	-0.6	-0.2	-0.1	0.0	0.4	-0.2	0.9	1.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.1	0.3	0.3	1.0	0.4	1.0	0.5	0.6	0.5	0.1	0.2	0.9	0.1
Medication: Ramipril	0.3	0.4	1.0	0.3	0.5	0.0	0.6	-1.0	0.7	0.6	0.7	0.3	0.7	1.0	0.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.4	-0.4	-0.1	-1.3	-1.0	-1.6	-0.8	-1.4	-1.0	-1.2	-1.0	-0.7	0.1
Happiness	0.3	0.3	2.5	0.2	0.6	0.4	0.0	0.3	-0.1	-0.0	0.0	0.1	-0.2	1.6	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	3.5	0.6	1.9	0.6	0.0	0.7	0.3	0.2	0.2	-0.2	-0.1	0.8	0.9
Pulse wave reflection index	0.3	0.4	1.0	-0.7	-0.0	-0.5	-0.6	-1.0	-0.5	-0.4	-0.6	-0.4	-0.5	-0.8	-0.8
Medication: Amlodipine	0.3	0.4	1.4	-0.0	1.0	-0.8	-0.1	1.2	-0.1	0.0	0.3	0.0	-0.1	1.1	0.3
Body fat percentage	0.3	1.3	5.1	0.8	0.9	1.4	0.8	1.7	0.9	1.0	0.9	1.0	0.8	-0.1	2.2
Comparative body size at age 10	0.3	0.9	6.2	0.1	-1.2	-0.4	-0.6	-0.1	-0.2	-0.6	-0.6	-0.3	-0.7	-2.5	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.2	1.2	0.6	-0.2	0.9	-0.1	-0.3	0.1	-0.5	-0.2	1.0	0.5
Medication: Seretide 50 evohaler	0.3	0.4	1.1	0.2	-0.9	-0.5	-0.5	-0.4	-0.6	-0.5	-0.4	-0.4	-0.9	-0.4	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.9	1.0	0.8	0.7	0.5	0.4	0.6	0.7	0.7	0.1	0.5	0.4	0.7
Illnesses of siblings: Diabetes	0.3	0.4	1.9	0.2	0.7	-0.3	-0.6	0.7	-0.3	-0.5	-0.4	-0.2	-0.6	0.4	1.4
Eye problems/disorders: Cataract	0.3	0.3	0.8	-0.4	0.5	0.1	-0.8	-0.4	-0.7	-0.8	-0.6	-0.2	-0.9	0.4	-0.6
Medication: Gliclazide	0.3	0.4	1.6	0.3	-1.3	0.5	-0.2	0.8	-0.1	-0.3	0.2	0.2	-0.1	-1.1	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.8	0.9	-0.5	0.2	0.7	0.8	0.6	0.8	0.9	0.1	0.7	-0.7	0.2
Medication: Atorvastatin	0.3	0.3	0.7	-0.5	-0.6	-0.7	-0.4	-0.7	-0.3	-0.6	-0.5	-0.6	-0.5	-0.9	-0.4
Leg fat mass (left)	0.3	1.2	4.3	0.4	-0.9	1.3	0.7	1.4	0.9	0.9	0.7	0.9	0.7	-2.1	1.3
Heel T-Score	0.2	1.7	7.0	0.8	1.5	-1.9	0.2	2.6	0.3	0.1	0.2	0.1	0.1	1.6	2.2
Cardiovascular Disease	0.2	0.6	3.7	-0.1	1.9	-0.7	-0.0	0.0	0.2	-0.0	0.2	0.4	-0.3	1.3	0.8
Average weekly spirits intake	0.2	0.3	1.1	-1.1	-0.3	-0.4	-0.4	0.1	-0.4	-0.4	-0.5	-0.4	-0.4	-0.5	-0.6
Medication for hormone replacement therapy	0.2	0.2	0.5	-0.7	-0.6	-0.1	-0.4	-0.7	-0.7	-0.2	-0.5	-0.6	-0.4	-0.1	-0.4
Supplements: Zinc	0.2	0.2	0.8	-0.2	0.0	0.9	0.2	-0.0	0.1	0.4	0.1	0.0	0.3	-0.9	0.7
Pack years adult smoking proportion	0.2	0.4	1.2	-0.8	0.9	-1.1	-0.5	-0.2	-0.3	-0.5	-0.4	-0.6	-0.4	0.3	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.3	0.1	0.2	-0.6	-0.5	-0.7	-0.5	-0.6	-0.3	-1.1	-0.6	-0.2	-0.1
Taking other prescription medications	0.2	0.4	1.0	0.9	0.7	1.0	0.3	0.8	0.0	0.3	0.5	0.3	0.2	0.7	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	-0.7	0.1	-0.8	-0.7	1.1	-0.7	-0.6	-0.7	-0.5	-0.6	-0.2	-0.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	-0.5	-0.0	-0.1	-0.5	0.5	-0.4	-0.6	-0.6	-0.6	-0.5	-0.5	-0.4
Multivitamins +/- minerals	0.2	0.2	1.1	0.5	-0.4	0.3	-0.0	0.6	0.0	0.1	-0.0	0.0	-0.0	-0.7	1.1
Medication: Levothyroxine sodium	0.2	0.4	1.0	-0.9	0.3	-0.6	-0.3	-1.0	-0.5	-0.2	-0.4	-0.2	-0.4	-0.9	-1.0
Trunk fat mass	0.2	0.7	2.2	0.5	-0.3	1.0	0.4	1.3	0.6	0.6	0.5	0.6	0.4	-1.5	1.3
Waist circumference	0.2	0.9	3.2	0.5	-0.7	1.3	0.5	1.1	0.7	0.7	0.6	0.8	0.6	-1.8	1.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.9	0.3	0.8	-0.0	-0.5	-0.3	-0.1	-0.5	-0.4	-0.1	-0.4	0.9	1.0
Father’s age at death	0.2	0.3	0.8	-0.4	0.0	0.2	-0.8	0.3	-0.6	-0.6	-0.6	-0.5	-0.9	0.2	0.1
Arm fat mass (right)	0.2	0.8	5.9	0.1	-0.9	0.8	0.3	0.7	0.6	0.5	0.4	0.6	0.4	-2.4	0.4
Length of working week for main job	0.2	0.2	0.6	0.5	0.3	0.3	0.3	-0.4	0.5	0.2	0.5	0.8	0.5	0.3	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.5	-0.3	0.4	-0.3	-0.5	-0.6	-0.3	-0.6	-0.5	-0.6	-0.4	0.7	-0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	2.5	0.4	-0.9	-0.0	-0.2	0.1	-0.2	-0.1	-0.1	-0.1	-0.2	0.1	-1.6
Forced vital capacity (FVC), Best measure	0.2	0.7	2.6	-0.5	-1.3	-0.8	-0.5	-0.6	-0.4	-0.7	-0.5	-0.8	-0.4	-1.6	-0.9
Exposure to tobacco smoke outside home	0.2	0.3	1.5	0.9	-0.3	0.4	0.3	0.4	0.4	0.3	0.3	0.6	0.4	-1.2	0.4
Number of children fathered	0.2	0.2	0.7	0.4	-0.8	0.3	0.1	-0.0	-0.1	0.2	0.1	-0.7	-0.0	0.4	-0.7
Emphysema/chronic bronchitis	0.2	0.2	0.7	-0.5	0.2	0.9	0.0	0.6	-0.0	-0.0	0.0	0.2	0.2	-0.1	-0.8
Neck or shoulder pain in last month	0.2	0.2	1.2	0.2	0.1	0.7	0.3	0.4	0.4	0.4	0.3	0.4	0.1	0.2	1.1
Medication: Omeprazole	0.2	0.3	1.0	0.5	0.8	1.0	0.1	0.5	0.1	0.2	0.1	-0.4	-0.1	0.9	-0.0
Mean time to correctly identify matches	0.2	0.4	1.2	-1.1	-0.7	-0.4	-0.2	0.8	-0.3	-0.2	-0.5	-0.1	-0.2	-1.1	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.9	-0.7	0.1	-0.1	-0.1	-1.4	-0.2	-0.3	-0.3	0.2	-0.5	0.6	0.2
Whole body fat mass	0.2	0.9	3.4	0.4	-0.6	1.0	0.5	1.4	0.7	0.7	0.6	0.7	0.5	-1.8	1.2
Alcohol intake frequency.	0.2	0.5	2.5	0.6	-0.4	1.6	0.7	0.7	0.5	0.8	0.9	0.3	0.7	0.1	-0.3
Number of full sisters	0.2	0.3	0.9	-0.0	1.0	0.3	-0.4	-0.9	-0.3	-0.4	-0.2	-0.0	-0.3	-0.0	0.9
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.2	0.4	-0.0	-0.8	-0.3	0.5	-0.5	0.0	-0.0	-1.1	-0.2	-0.2	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.2	0.9	0.1	0.2	-0.4	-0.3	-0.3	-0.2	-0.3	-1.1	-0.6	-0.4	0.5
Ever had bowel cancer screening	0.2	0.2	0.7	0.2	0.2	0.6	0.4	0.8	0.0	0.4	0.4	0.5	0.5	0.2	0.1
Osteoarthritis (self-reported)	0.2	0.2	0.7	0.2	-0.5	-0.7	-0.4	-0.9	-0.6	-0.3	-0.4	-0.7	-0.3	0.1	0.0
Arm fat mass (left)	0.2	0.6	5.0	-0.0	-0.9	0.6	0.2	0.6	0.5	0.3	0.2	0.5	0.3	-2.2	0.5
Average weekly champagne plus white wine intake	0.2	0.3	0.8	0.2	-0.4	0.2	0.7	-0.4	0.6	0.5	0.5	0.9	0.8	-0.5	-0.5
Mother’s age at death	0.2	0.2	1.3	-0.2	-0.5	0.6	0.1	0.8	0.2	-0.2	-0.0	0.2	0.2	-1.1	-0.2
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.9	-0.0	-1.0	0.7	0.4	-0.6	0.0	0.2	0.3	0.4	0.5	-0.2	-0.8
Medication: Blood pressure	0.2	0.4	1.4	-0.8	0.4	-1.2	-0.5	-0.4	-0.6	-0.4	-0.3	-0.1	-0.7	-0.1	-1.0
Medication: Bendroflumethiazide	0.2	0.4	1.0	-0.4	0.1	0.0	0.7	1.0	0.7	0.6	0.9	0.6	0.7	0.0	-0.4
Bipolar Disorder or Schizophrenia	0.1	0.2	0.8	-0.7	0.1	0.7	0.0	0.6	-0.2	0.0	-0.1	0.2	0.0	0.3	-0.9
Depression (Nagel 2018)	0.1	0.2	0.4	0.7	0.6	-0.5	-0.3	-0.1	-0.2	-0.3	-0.2	-0.6	-0.5	-0.2	0.3
Major Depression (MDD)	0.1	0.2	0.3	0.4	0.5	-0.4	-0.6	0.1	-0.2	-0.5	-0.3	-0.2	-0.4	0.6	0.5
Reaction Time	0.1	0.2	0.6	-0.7	-0.0	-0.1	-0.1	0.8	-0.0	-0.0	-0.3	0.1	-0.0	-0.3	0.7
Breast Cancer	0.1	0.2	1.2	-0.5	0.2	-0.2	0.3	1.1	0.2	0.3	0.2	0.4	0.3	-0.6	0.5
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.9	-0.9	-0.1	0.1	0.1	-0.2	-0.1	-0.1	0.1	-0.2	0.2	-0.3	-0.5
Blood White Count	0.1	0.6	4.3	-0.7	0.6	0.4	0.1	-2.1	-0.1	0.3	0.2	0.6	0.4	0.7	0.6
Hair Pigment	0.1	2.1	4.0	0.5	-2.0	1.6	1.4	1.5	1.4	1.7	1.2	0.8	1.5	-1.3	-1.7
Relative age of first facial hair	0.1	0.2	1.8	-1.3	0.1	-0.6	-0.1	-0.2	-0.6	-0.1	-0.3	-0.1	0.1	0.5	-0.1
Angina	0.1	0.2	0.5	-0.1	0.5	-0.7	-0.5	-0.1	-0.2	-0.4	-0.3	-0.6	-0.5	0.3	0.1
Medication: Metformin	0.1	0.1	0.3	-0.3	-0.5	-0.1	-0.3	0.2	-0.4	-0.4	-0.2	-0.5	-0.2	0.0	-0.3
High blood pressure	0.1	0.2	1.1	0.1	0.5	-0.7	0.3	1.1	0.4	0.2	0.5	0.5	0.0	0.2	-0.1
Supplements: Glucosamine	0.1	0.2	1.1	1.1	0.1	0.3	0.0	-0.1	-0.0	-0.0	0.2	-0.1	-0.1	0.8	0.6
Medication: Atenolol	0.1	0.2	1.0	-0.4	0.3	-0.5	-0.0	-0.4	0.1	-0.1	-0.1	-0.0	-0.0	-0.3	-1.0
Sitting height	0.1	0.7	3.5	0.6	0.2	0.7	0.2	0.4	0.8	0.4	0.0	-0.1	-0.1	-1.7	1.9
Body mass index (BMI)	0.1	0.6	5.0	-0.7	-1.0	0.3	0.1	0.1	0.2	0.1	0.0	0.5	0.1	-2.2	0.1
Past tobacco smoking	0.1	0.1	1.1	-0.0	-0.2	0.3	-0.2	0.2	-0.1	-0.2	-0.1	-0.1	-0.3	-0.1	-1.1
Forced vital capacity (FVC)	0.1	0.6	1.6	-0.5	-0.8	-0.4	-0.5	-1.2	-0.5	-0.8	-0.6	-0.9	-0.6	-1.1	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.5	0.2	-0.6	-0.4	-0.0	1.2	-0.1	0.0	-0.1	-0.2	0.1	-0.6	-1.2
Qualifications: None of the above	0.1	0.3	0.9	-0.3	-0.5	0.3	0.4	-0.3	0.3	0.5	0.3	0.4	0.3	-1.0	0.9
Heart attack	0.1	0.2	0.5	-0.2	-0.4	0.6	0.5	-0.3	0.7	0.6	0.4	0.0	0.4	-0.5	-0.4
Arm fat percentage (right)	0.1	0.3	1.2	-0.3	0.9	0.3	0.0	0.7	0.1	0.2	0.2	0.4	0.0	-0.5	1.1
Pulse wave Arterial Stiffness index	0.1	0.1	0.3	0.1	-0.0	-0.3	-0.3	-0.1	-0.0	-0.2	-0.2	-0.1	-0.4	-0.6	-0.3
Birth weight of first child	0.1	0.2	0.7	-0.0	0.5	-0.4	-0.7	0.1	-0.5	-0.5	-0.4	-0.3	-0.8	0.4	0.3
Wheeze or whistling in the chest in last year	0.1	0.2	0.7	0.5	0.4	0.6	-0.1	0.6	-0.1	-0.1	0.2	-0.1	-0.0	-0.8	0.8
Pulse wave peak to peak time	0.1	0.2	0.3	0.2	-0.2	0.5	0.5	0.3	0.2	0.5	0.4	0.3	0.6	0.3	0.3
Angina (self-reported)	0.1	0.1	0.4	0.2	0.5	-0.5	-0.3	0.1	0.0	-0.1	-0.0	-0.6	-0.3	0.4	0.3
Hypertension (Self-reported)	0.1	0.3	1.3	0.3	0.4	-0.6	0.4	1.1	0.5	0.3	0.7	0.7	0.1	0.3	-0.0
Smoking status: Previous	0.1	0.1	0.6	-0.2	-0.6	0.0	0.4	0.0	0.2	0.3	0.1	0.2	0.4	-0.1	0.8
Arm fat percentage (left)	0.1	0.3	1.4	-0.0	0.6	0.4	0.3	0.7	0.3	0.4	0.4	0.6	0.3	-0.5	1.2
Handedness (chirality/laterality): Left-handed	0.1	0.2	1.0	-0.3	0.1	0.2	0.1	0.3	0.1	0.1	0.1	0.8	0.4	-0.1	-1.0
Mineral and other dietary supplements	0.1	0.1	0.8	0.1	0.9	-0.1	-0.0	-0.1	0.2	-0.0	0.1	0.3	-0.1	0.1	0.6
Miserableness	0.1	0.2	1.4	1.0	1.2	0.3	0.1	0.2	0.3	-0.0	0.2	0.2	0.0	-0.2	0.3
Financial situation satisfaction	0.1	0.1	0.3	0.1	0.4	0.5	0.3	0.6	0.1	0.4	0.4	-0.0	0.3	-0.1	0.2
Alcohol drinker status: Never	0.1	0.1	0.6	-0.5	0.1	0.3	-0.3	0.0	-0.5	-0.3	-0.3	0.0	-0.4	-0.0	-0.8
Ever smoked	0.1	0.1	1.0	0.6	0.2	-0.3	-0.1	-0.1	-0.0	0.0	-0.1	0.0	-0.1	-0.3	1.0
Age started oral contraceptive pill	0.1	0.2	0.4	-0.5	-0.0	0.4	-0.4	0.2	-0.6	-0.4	-0.4	-0.2	-0.5	0.3	0.3
Unable to work because of sickness or disability	0.1	0.2	1.0	0.1	0.5	-0.0	-0.0	-0.6	0.2	-0.0	0.1	-0.2	0.2	0.4	1.0
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.7	-0.1	-0.5	0.6	-0.3	-0.9	-0.4	-0.3	-0.6	-0.5	-0.1	-0.3	0.1
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	-0.4	-0.1	0.3	0.2	-0.3	0.5	0.3	0.2	-0.2	0.1	-0.2	-0.3
Pack years of smoking	0.1	0.1	0.3	-0.5	0.4	-0.6	-0.1	0.4	0.1	-0.1	0.0	-0.1	-0.0	0.1	-0.5
Primary Biliary Cirrhosis	0.0	0.1	0.2	-0.3	-0.1	0.5	0.1	-0.4	0.0	0.3	-0.0	0.0	0.1	0.3	-0.4
Heart disease (siblings)	0.0	0.1	0.2	-0.2	-0.1	0.5	0.2	0.1	0.5	0.0	0.1	-0.3	0.1	-0.2	-0.1

Hub : Genes

ZNF143

Models

Trait associations