Best TWAS P=4.25e-09 · Best GWAS P=1.08e-11 conditioned to 0.000587
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | RP11-613D13.5 | 0.18 | 0.11 | lasso | 5 | 0.15 | 6.3e-08 | 4.0 | -5.5 | 3.0e-08 | 0.78 | 0.27 | 0.68 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | RP11-613D13.5 | 0.14 | 0.01 | lasso | 2 | 0.02 | 8.1e-02 | -3.5 | -5.8 | 8.8e-09 | 0.73 | 0.05 | 0.44 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | RP11-613D13.5 | 0.18 | 0.02 | enet | 11 | 0.07 | 5.3e-04 | 4.0 | -5.2 | 2.6e-07 | 0.70 | 0.22 | 0.72 | FALSE |
| 4 | GTEx | Whole Blood | RP11-613D13.5 | 0.06 | 0.01 | lasso | 4 | 0.00 | 1.2e-01 | -6.3 | -5.9 | 4.3e-09 | 0.88 | 0.04 | 0.50 | TRUE |