TWAS
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Comparative height size at age 10
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chr11:43,152,325-44,596,817
Best TWAS P=4.25e-09 · Best GWAS P=1.08e-11 conditioned to 0.000587
43.2M
43.4M
43.6M
43.8M
44M
44.2M
44.4M
44.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
GTEx
Whole Blood
RP11-613D13.5
0.06
0.01
lasso
4
0.00
1.2e-01
-6.3
-5.9
4.3e-09
0.88
0.04
0.50
TRUE
2
GTEx
Breast Mammary Tissue (Female)
RP11-613D13.5
0.14
0.01
lasso
2
0.02
8.1e-02
-3.5
-5.8
8.8e-09
0.73
0.05
0.44
FALSE
1
GTEx
Breast Mammary Tissue
RP11-613D13.5
0.18
0.11
lasso
5
0.15
6.3e-08
4.0
-5.5
3.0e-08
0.78
0.27
0.68
FALSE
3
GTEx
Heart Atrial Appendage
RP11-613D13.5
0.18
0.02
enet
11
0.07
5.3e-04
4.0
-5.2
2.6e-07
0.70
0.22
0.72
FALSE