[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr11:46,010,847-48,783,497

Best TWAS P=6.99e-14 · Best GWAS P=1.37e-12 conditioned to 0.103

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MTCH2	0.03	0.00	bslmm	299	0.00	1.1e-01	2.9	-5.9	3.0e-09	-0.17	0.14	0.08	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PSMC3	0.04	0.00	enet	22	0.01	3.8e-02	5.1	-5.2	1.5e-07	-0.26	0.14	0.13	FALSE
3	GTEx	Adipose Subcutaneous	PTPRJ	0.05	0.05	lasso	2	0.04	3.9e-04	5.6	5.6	2.3e-08	0.19	0.21	0.38	FALSE
4	GTEx	Adipose Visceral Omentum	ARHGAP1	0.12	0.02	enet	15	0.04	3.8e-03	3.4	-5.7	1.6e-08	-0.46	0.07	0.38	TRUE
5	GTEx	Artery Aorta	MADD	0.09	0.03	enet	22	0.04	1.9e-03	-3.1	5.2	2.2e-07	0.52	0.10	0.31	FALSE
6	GTEx	Artery Aorta	PACSIN3	0.10	0.04	lasso	4	0.03	1.1e-02	2.9	5.8	6.6e-09	0.58	0.15	0.61	FALSE
7	GTEx	Brain Cerebellar Hemisphere	ACP2	0.29	0.05	enet	16	0.12	5.9e-04	3.6	-5.5	3.8e-08	-0.79	0.06	0.32	FALSE
8	GTEx	Brain Cortex	MTCH2	0.21	0.19	lasso	6	0.16	4.0e-05	-6.0	-6.4	1.6e-10	-0.34	0.30	0.30	FALSE
9	GTEx	Brain Hypothalamus	NR1H3	0.25	0.18	lasso	5	0.10	2.7e-03	5.9	5.8	5.2e-09	0.89	0.06	0.65	FALSE
10	GTEx	Brain Putamen basal ganglia	CKAP5	0.25	0.07	lasso	3	0.14	4.4e-04	3.1	5.2	1.6e-07	0.70	0.05	0.22	FALSE
11	GTEx	Breast Mammary Tissue (Female)	PSMC3	0.02	0.01	lasso	1	0.04	2.5e-02	6.7	-6.7	2.5e-11	-0.67	0.02	0.18	FALSE
12	GTEx	Cells Transformed fibroblasts	PSMC3	0.07	0.00	enet	13	0.02	2.3e-02	6.7	-6.3	2.1e-10	-0.60	0.07	0.43	FALSE
13	GTEx	Cells Transformed fibroblasts	C1QTNF4	0.13	0.11	enet	19	0.12	5.2e-09	-6.1	5.5	4.8e-08	0.43	0.50	0.50	FALSE
14	GTEx	Colon Transverse	C1QTNF4	0.07	0.02	lasso	6	0.03	2.0e-02	-4.6	5.3	9.6e-08	0.36	0.20	0.37	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	CKAP5	0.11	0.04	lasso	3	0.03	2.1e-02	5.1	5.9	3.2e-09	0.84	0.16	0.46	FALSE
16	GTEx	Esophagus Mucosa	ARFGAP2	0.05	0.06	lasso	4	0.05	4.4e-04	5.1	5.1	2.9e-07	0.68	0.32	0.06	FALSE
17	GTEx	Esophagus Muscularis	C1QTNF4	0.10	0.05	enet	23	0.06	1.4e-04	-4.6	5.2	2.1e-07	0.38	0.68	0.20	FALSE
18	GTEx	Lung	ACP2	0.04	0.03	lasso	2	0.04	4.3e-04	6.2	-5.6	2.0e-08	-0.91	0.08	0.86	FALSE
19	GTEx	Lung	PSMC3	0.07	0.02	lasso	2	0.03	3.6e-03	5.1	-5.5	3.9e-08	-0.40	0.17	0.12	FALSE
20	GTEx	Lung	C1QTNF4	0.18	0.15	lasso	6	0.13	3.2e-10	-4.7	5.2	1.5e-07	0.32	0.64	0.36	FALSE
21	GTEx	Muscle Skeletal	MTCH2	0.05	0.03	enet	15	0.04	1.5e-04	-5.4	-5.5	3.7e-08	-0.44	0.53	0.38	FALSE
22	GTEx	Muscle Skeletal	SLC39A13	0.05	0.01	lasso	3	0.01	8.5e-02	5.1	-6.1	1.1e-09	-0.52	0.06	0.46	FALSE
23	GTEx	Nerve Tibial	LRP4	0.28	0.24	enet	24	0.30	3.5e-21	-5.0	5.8	4.8e-09	0.66	1.00	0.00	FALSE
24	GTEx	Nerve Tibial	PTPRJ	0.05	0.03	enet	13	0.03	2.7e-03	3.2	5.5	3.5e-08	0.26	0.14	0.33	FALSE
25	GTEx	Nerve Tibial	SLC39A13	0.07	0.01	enet	14	0.02	7.6e-03	-4.7	-6.2	5.1e-10	-0.60	0.04	0.79	FALSE
26	GTEx	Nerve Tibial	C1QTNF4	0.20	0.23	enet	12	0.23	1.7e-16	-4.5	5.2	2.5e-07	0.47	0.99	0.01	FALSE
27	GTEx	Pancreas	LRP4	0.11	0.10	enet	16	0.14	1.8e-06	5.1	-5.6	1.7e-08	-0.75	0.32	0.65	FALSE
28	GTEx	Pancreas	LRP4-AS1	0.10	0.08	lasso	6	0.12	1.4e-05	5.1	-5.7	1.1e-08	-0.66	0.32	0.59	FALSE
29	GTEx	Prostate	PSMC3	0.21	0.10	lasso	6	0.20	7.9e-06	5.2	-6.7	2.3e-11	-0.62	0.09	0.42	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	LRP4	0.13	0.00	lasso	7	0.02	3.5e-02	5.1	7.1	1.2e-12	0.69	0.06	0.59	FALSE
31	GTEx	Skin Not Sun Exposed Suprapubic	DDB2	0.07	0.02	enet	13	0.04	3.5e-03	6.2	6.2	5.7e-10	0.73	0.06	0.59	FALSE
32	GTEx	Skin Not Sun Exposed Suprapubic	PACSIN3	0.11	0.05	lasso	3	0.10	3.4e-06	3.8	5.7	1.4e-08	0.73	0.18	0.72	FALSE
33	GTEx	Skin Sun Exposed Lower leg	ACP2	0.16	0.14	enet	15	0.15	1.8e-12	5.9	-6.7	1.8e-11	-0.90	0.08	0.92	FALSE
34	GTEx	Skin Sun Exposed Lower leg	PACSIN3	0.17	0.11	lasso	4	0.12	5.5e-10	3.8	5.5	4.6e-08	0.68	0.94	0.06	FALSE
35	GTEx	Skin Sun Exposed Lower leg	PSMC3	0.20	0.05	lasso	7	0.10	1.2e-08	6.7	-6.5	9.3e-11	-0.50	0.08	0.92	FALSE
36	GTEx	Skin Sun Exposed Lower leg	ARHGAP1	0.08	0.01	lasso	5	0.02	1.4e-02	4.8	-5.4	6.1e-08	-0.64	0.04	0.84	FALSE
37	GTEx	Testis	NR1H3	0.10	0.10	lasso	6	0.08	2.9e-04	7.1	-6.8	8.0e-12	-0.99	0.01	0.99	FALSE
38	GTEx	Whole Blood	C1QTNF4	0.09	0.05	lasso	3	0.03	1.4e-03	-6.0	6.1	9.8e-10	0.31	0.40	0.38	FALSE
39	METSIM	Adipose	ACP2	0.05	0.04	blup	302	0.06	1.7e-09	-4.7	-5.9	2.9e-09	-0.62	0.58	0.42	FALSE
40	METSIM	Adipose	ARHGAP1	0.08	0.02	enet	23	0.06	3.6e-09	4.9	-5.6	2.1e-08	-0.53	0.07	0.92	FALSE
41	METSIM	Adipose	C1QTNF4	0.24	0.31	lasso	7	0.31	1.2e-46	-6.0	6.1	8.1e-10	0.32	0.52	0.48	FALSE
42	METSIM	Adipose	MADD	0.05	0.02	bslmm	315	0.02	8.3e-04	4.5	5.8	6.7e-09	0.60	0.19	0.29	FALSE
43	METSIM	Adipose	MYBPC3	0.11	0.10	enet	26	0.11	1.0e-15	-4.7	5.5	3.8e-08	0.42	0.88	0.12	FALSE
44	METSIM	Adipose	PSMC3	0.06	0.03	enet	28	0.04	2.3e-06	-5.0	-6.8	1.0e-11	-0.45	0.13	0.86	FALSE
45	METSIM	Adipose	RAPSN	0.11	0.01	enet	21	0.06	7.9e-09	2.7	6.0	2.3e-09	0.63	0.03	0.97	FALSE
46	NTR	Blood	MADD	0.01	0.01	enet	8	0.01	4.7e-03	5.9	5.1	3.1e-07	0.61	0.14	0.20	FALSE
47	NTR	Blood	MTCH2	0.02	0.04	lasso	1	0.04	1.3e-11	-6.1	6.1	9.3e-10	0.30	0.49	0.51	FALSE
48	ROSMAP	Brain Pre-frontal Cortex	MTCH2	0.35	0.40	enet	9	0.40	4.7e-56	-6.0	-6.0	2.5e-09	-0.32	0.49	0.51	FALSE
49	ROSMAP	Brain Pre-frontal Cortex	ACP2	0.03	0.00	blup	295	0.02	1.5e-03	-4.9	-6.2	5.7e-10	-0.76	0.10	0.76	FALSE
50	ROSMAP	Brain Pre-frontal Cortex	C11orf49	0.02	0.02	blup	322	0.02	3.3e-04	4.9	5.3	1.2e-07	0.70	0.74	0.19	FALSE
51	ROSMAP	Brain Pre-frontal Cortex	CELF1	0.03	0.01	bslmm	289	0.01	2.9e-02	5.4	7.5	7.0e-14	0.63	0.05	0.74	TRUE
52	ROSMAP	Brain Pre-frontal Cortex	PSMC3	0.15	0.08	bslmm	285	0.10	5.1e-13	5.1	-6.9	5.3e-12	-0.54	0.10	0.90	FALSE
53	ROSMAP	Brain Pre-frontal Cortex	C1QTNF4	0.05	0.06	blup	281	0.06	1.7e-08	-4.9	7.3	3.7e-13	0.58	0.75	0.25	FALSE
54	YFS	Blood	CKAP5	0.01	0.01	bslmm	291	0.01	3.6e-03	4.3	-5.3	1.3e-07	-0.40	0.03	0.18	FALSE
55	YFS	Blood	NR1H3	0.34	0.15	enet	66	0.24	3.1e-76	6.2	-5.6	1.7e-08	-0.70	0.40	0.60	FALSE
56	YFS	Blood	NUP160	0.02	0.01	blup	290	0.01	1.7e-04	-6.2	-5.4	6.2e-08	-0.48	0.14	0.78	FALSE
57	YFS	Blood	PSMC3	0.02	0.01	blup	289	0.01	2.8e-05	-4.6	-6.6	4.1e-11	-0.68	0.16	0.77	FALSE
58	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1QTNF4	0.06	0.07	lasso	2	0.06	4.9e-06	-6.1	5.8	8.0e-09	0.33	0.00	1.00	FALSE
59	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUP160	0.03	0.01	blup	44	0.01	1.9e-03	-5.4	-5.5	4.5e-08	-0.26	0.01	0.59	FALSE
60	The Cancer Genome Atlas	Colon Adenocarcinoma	KBTBD4	0.14	0.01	blup	13	0.02	1.6e-02	2.2	-6.2	5.5e-10	-0.51	0.00	0.52	FALSE
61	The Cancer Genome Atlas	Esophageal Carcinoma	C1QTNF4	0.39	0.33	blup	15	0.35	6.1e-12	-4.5	5.3	1.2e-07	0.39	0.00	1.00	FALSE
62	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1QTNF4	0.06	0.08	lasso	3	0.08	7.5e-09	-6.0	6.0	1.8e-09	0.30	0.00	1.00	FALSE
63	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FNBP4	0.10	0.03	blup	45	0.05	7.7e-06	-6.2	-5.4	7.4e-08	-0.16	0.00	0.99	FALSE
64	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NUP160	0.08	0.03	blup	42	0.04	6.7e-05	-6.1	-5.1	2.8e-07	-0.26	0.01	0.97	FALSE
65	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ACP2	0.03	0.03	blup	44	0.04	3.5e-05	7.1	-5.9	3.3e-09	-0.94	0.01	0.99	FALSE
66	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1QTNF4	0.12	0.14	enet	4	0.16	6.5e-18	-6.0	5.6	2.3e-08	0.35	0.00	1.00	FALSE
67	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMC3	0.05	0.04	lasso	3	0.05	3.8e-06	-5.0	-5.2	2.2e-07	-0.34	0.81	0.07	FALSE
68	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1QTNF4	0.13	0.16	lasso	1	0.16	3.1e-09	-6.1	6.1	9.5e-10	0.30	0.00	1.00	FALSE
69	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACP2	0.09	0.04	enet	12	0.06	5.0e-07	5.9	-5.4	5.9e-08	-0.73	0.08	0.92	FALSE
70	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTCH2	0.11	0.11	lasso	2	0.10	6.4e-12	-6.0	-6.0	1.6e-09	-0.30	0.00	1.00	FALSE
71	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYBPC3	0.03	0.01	blup	43	0.02	3.2e-03	-4.7	5.7	1.5e-08	0.47	0.05	0.15	FALSE
72	The Cancer Genome Atlas	Brain Lower Grade Glioma	PSMC3	0.10	0.05	blup	39	0.08	3.7e-09	-4.7	-5.9	3.7e-09	-0.51	0.01	0.98	FALSE
73	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1QTNF4	0.19	0.19	lasso	3	0.19	3.2e-09	-6.0	6.0	1.6e-09	0.30	0.00	1.00	FALSE
74	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DDB2	0.02	0.03	lasso	1	0.02	1.0e-03	6.2	6.2	5.5e-10	0.91	0.01	0.91	FALSE
75	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC39A13	0.06	0.01	blup	58	0.04	9.3e-04	5.7	-5.7	1.4e-08	-0.22	0.03	0.26	FALSE
76	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMC3	0.02	0.02	blup	39	0.02	5.7e-03	-4.7	-6.4	1.9e-10	-0.52	0.02	0.38	FALSE
77	The Cancer Genome Atlas	Stomach Adenocarcinoma	C1QTNF4	0.06	0.04	lasso	4	0.03	4.3e-03	-6.1	5.9	4.3e-09	0.34	0.00	0.94	FALSE