[Hub]/) : Traits : Comparative height size at age 10 :

chr11:73,825,503-75,359,175

Best TWAS P=1.44e-08 · Best GWAS P=4.82e-21 conditioned to 5.25e-20

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex XRRA1 0.59 0.79 lasso 3 0.78 5.8e-152 5.2 5.3 1.4e-07 0.05 0.05 0.95 FALSE
2 GTEx Adipose Subcutaneous XRRA1 0.49 0.62 enet 27 0.64 6.1e-67 5.3 5.2 2.0e-07 0.04 0.04 0.96 FALSE
3 GTEx Artery Aorta XRRA1 0.57 0.65 lasso 7 0.68 1.1e-50 5.2 5.2 2.0e-07 0.04 0.05 0.95 FALSE
4 GTEx Artery Coronary XRRA1 0.72 0.71 enet 24 0.73 4.8e-35 5.2 5.2 2.4e-07 0.04 0.06 0.94 FALSE
5 GTEx Artery Tibial XRRA1 0.63 0.72 lasso 10 0.74 1.9e-83 5.2 5.2 2.0e-07 0.04 0.04 0.96 FALSE
6 GTEx Brain Caudate basal ganglia XRRA1 0.72 0.61 lasso 5 0.60 2.6e-21 5.3 5.2 1.5e-07 0.04 0.04 0.96 FALSE
7 GTEx Brain Cerebellar Hemisphere XRRA1 0.79 0.74 lasso 8 0.74 2.5e-27 5.4 5.3 1.1e-07 0.04 0.04 0.96 FALSE
8 GTEx Brain Cerebellar Hemisphere RP11-147I3.1 0.36 0.12 lasso 7 0.13 2.6e-04 5.4 -5.4 6.5e-08 -0.04 0.06 0.91 FALSE
9 GTEx Brain Cerebellum XRRA1 0.67 0.65 lasso 9 0.69 2.7e-27 5.3 5.3 8.9e-08 0.04 0.04 0.96 FALSE
10 GTEx Brain Nucleus accumbens basal ganglia XRRA1 0.70 0.50 lasso 8 0.51 1.0e-15 5.3 5.6 2.7e-08 0.03 0.04 0.95 FALSE
11 GTEx Brain Nucleus accumbens basal ganglia RP11-147I3.1 0.23 0.20 lasso 1 0.17 2.9e-05 5.4 -5.4 8.5e-08 -0.04 0.06 0.84 FALSE
12 GTEx Brain Putamen basal ganglia XRRA1 0.55 0.50 lasso 3 0.50 9.3e-14 5.3 5.3 1.2e-07 0.05 0.05 0.95 FALSE
13 GTEx Brain Putamen basal ganglia RP11-147I3.1 0.19 0.20 lasso 2 0.20 2.0e-05 5.3 -5.3 1.2e-07 -0.05 0.06 0.87 FALSE
14 GTEx Breast Mammary Tissue XRRA1 0.48 0.57 lasso 1 0.57 8.3e-35 5.2 5.2 1.8e-07 0.04 0.05 0.95 FALSE
15 GTEx Cells EBV-transformed lymphocytes XRRA1 0.64 0.72 lasso 4 0.71 6.1e-32 5.3 5.3 1.0e-07 0.04 0.04 0.96 FALSE
16 GTEx Esophagus Gastroesophageal Junction XRRA1 0.55 0.68 enet 17 0.68 5.2e-33 5.2 5.1 3.0e-07 0.04 0.05 0.95 FALSE
17 GTEx Esophagus Mucosa XRRA1 0.64 0.76 lasso 7 0.76 5.9e-75 5.2 5.2 1.5e-07 0.04 0.04 0.96 FALSE
18 GTEx Esophagus Mucosa RP11-147I3.1 0.20 0.12 lasso 4 0.12 1.2e-08 5.2 -5.3 1.4e-07 -0.04 0.05 0.95 FALSE
19 GTEx Esophagus Muscularis XRRA1 0.59 0.70 lasso 5 0.70 1.2e-58 5.3 5.3 1.4e-07 0.04 0.04 0.96 FALSE
20 GTEx Heart Left Ventricle XRRA1 0.58 0.69 lasso 6 0.69 1.0e-49 5.2 5.2 1.5e-07 0.04 0.04 0.96 FALSE
21 GTEx Heart Left Ventricle RP11-147I3.1 0.21 0.14 lasso 3 0.14 4.6e-08 5.0 -5.2 2.2e-07 -0.03 0.06 0.94 FALSE
22 GTEx Lung XRRA1 0.66 0.70 enet 35 0.72 1.1e-78 5.2 5.2 1.7e-07 0.04 0.04 0.96 FALSE
23 GTEx Muscle Skeletal XRRA1 0.53 0.68 enet 16 0.72 8.9e-100 5.2 5.2 2.3e-07 0.03 0.04 0.96 FALSE
24 GTEx Nerve Tibial XRRA1 0.52 0.67 lasso 5 0.68 3.6e-64 5.3 5.2 1.7e-07 0.04 0.04 0.96 FALSE
25 GTEx Pancreas XRRA1 0.56 0.64 lasso 5 0.64 1.4e-34 5.3 5.3 1.0e-07 0.04 0.04 0.96 FALSE
26 GTEx Pancreas RP11-147I3.1 0.28 0.18 lasso 7 0.20 1.2e-08 5.3 -5.4 6.0e-08 -0.04 0.06 0.94 FALSE
27 GTEx Pituitary XRRA1 0.67 0.68 lasso 3 0.68 6.4e-23 5.4 5.4 8.4e-08 0.04 0.04 0.96 FALSE
28 GTEx Prostate XRRA1 0.80 0.63 lasso 12 0.69 1.5e-23 5.3 5.2 1.6e-07 0.03 0.05 0.95 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic XRRA1 0.51 0.59 enet 12 0.60 5.3e-41 5.2 5.3 1.4e-07 0.04 0.04 0.95 FALSE
30 GTEx Skin Sun Exposed Lower leg XRRA1 0.50 0.65 lasso 6 0.66 7.4e-72 5.2 5.2 2.4e-07 0.04 0.05 0.95 FALSE
31 GTEx Small Intestine Terminal Ileum RP11-147I3.1 0.32 0.08 lasso 6 0.06 2.1e-02 5.2 -5.2 1.9e-07 -0.04 0.10 0.63 FALSE
32 GTEx Stomach XRRA1 0.57 0.64 lasso 6 0.66 7.9e-41 5.3 5.2 1.8e-07 0.03 0.04 0.96 FALSE
33 GTEx Thyroid XRRA1 0.66 0.76 lasso 4 0.76 1.1e-88 5.2 5.2 1.6e-07 0.05 0.05 0.95 FALSE
34 GTEx Uterus XRRA1 0.59 0.59 lasso 7 0.59 6.9e-15 5.3 5.3 1.3e-07 0.04 0.06 0.94 FALSE
35 GTEx Vagina XRRA1 0.72 0.75 lasso 4 0.76 2.5e-25 5.3 5.2 2.5e-07 0.04 0.04 0.96 FALSE
36 NTR Blood XRRA1 0.09 0.16 lasso 3 0.16 3.2e-49 5.3 5.2 1.6e-07 0.04 0.04 0.95 FALSE
37 ROSMAP Brain Pre-frontal Cortex XRRA1 0.56 0.72 bslmm 505 0.72 6.2e-136 5.3 5.4 7.8e-08 0.04 0.04 0.96 FALSE
38 ROSMAP Brain Pre-frontal Cortex RP11-147I3.1 0.28 0.41 lasso 4 0.41 6.9e-57 5.2 -5.3 1.2e-07 -0.04 0.04 0.96 FALSE
39 The Cancer Genome Atlas Bladder Urothelial Carcinoma XRRA1 0.34 0.39 enet 10 0.39 5.6e-35 5.2 5.1 2.8e-07 0.04 0.02 0.98 FALSE
40 The Cancer Genome Atlas Breast Invasive Carcinoma XRRA1 0.29 0.43 lasso 4 0.43 2.7e-97 5.2 5.2 1.8e-07 0.04 0.01 0.99 FALSE
41 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma XRRA1 0.34 0.30 lasso 3 0.29 1.0e-14 5.3 5.3 1.1e-07 0.05 0.01 0.99 FALSE
42 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma XRRA1 0.28 0.38 lasso 4 0.38 1.3e-44 5.4 5.3 1.5e-07 0.04 0.01 0.99 FALSE
43 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XRRA1 0.52 0.69 lasso 6 0.70 2.8e-111 5.3 5.2 2.0e-07 0.04 0.01 0.99 FALSE
44 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma XRRA1 0.40 0.54 lasso 7 0.54 1.2e-35 5.3 5.3 1.0e-07 0.04 0.01 0.99 FALSE
45 The Cancer Genome Atlas Liver Hepatocellular Carcinoma XRRA1 0.37 0.36 blup 73 0.36 5.7e-18 5.2 5.7 1.4e-08 0.05 0.01 0.99 TRUE
46 The Cancer Genome Atlas Lung Adenocarcinoma XRRA1 0.39 0.54 lasso 4 0.53 5.7e-73 5.2 5.3 1.4e-07 0.04 0.01 0.99 FALSE
47 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma XRRA1 0.45 0.53 lasso 3 0.53 4.2e-42 5.3 5.3 1.3e-07 0.05 0.01 0.99 FALSE
48 The Cancer Genome Atlas Rectum Adenocarcinoma XRRA1 0.65 0.69 lasso 3 0.69 1.6e-21 5.3 5.3 9.3e-08 0.04 0.01 0.99 FALSE
49 The Cancer Genome Atlas Soft Tissue Sarcoma XRRA1 0.27 0.34 lasso 4 0.34 7.5e-21 5.4 5.3 1.2e-07 0.04 0.01 0.99 FALSE
50 The Cancer Genome Atlas Skin Cutaneous Melanoma XRRA1 0.37 0.40 lasso 8 0.37 5.7e-11 5.2 5.3 1.4e-07 0.04 0.01 0.99 FALSE
51 The Cancer Genome Atlas Stomach Adenocarcinoma XRRA1 0.49 0.58 lasso 9 0.57 6.3e-50 5.2 5.1 3.1e-07 0.04 0.01 0.99 FALSE
52 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma XRRA1 0.41 0.32 lasso 8 0.30 3.4e-09 5.2 5.2 2.5e-07 0.05 0.01 0.99 FALSE