[Hub]/) : Traits : Comparative height size at age 10 :

chr12:27,587,038-30,229,606

Best TWAS P=1.07e-37 · Best GWAS P=7.24e-34 conditioned to 0.00222

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC91 0.08 0.06 lasso 6 0.07 9.4e-09 -11.7 10.0 1.7e-23 -0.92 0.10 0.90 FALSE
2 GTEx Adipose Subcutaneous RP11-996F15.2 0.46 0.38 lasso 10 0.38 4.1e-33 7.3 7.1 1.7e-12 0.04 0.00 1.00 FALSE
3 GTEx Adipose Visceral Omentum RP11-996F15.2 0.40 0.34 enet 12 0.33 7.9e-18 7.3 6.9 4.4e-12 0.03 0.00 1.00 FALSE
4 GTEx Adrenal Gland CCDC91 0.16 0.01 lasso 16 0.03 3.5e-02 4.1 -6.8 1.2e-11 0.39 0.08 0.51 FALSE
5 GTEx Adrenal Gland RP11-996F15.2 0.62 0.55 lasso 7 0.55 3.0e-23 7.3 7.3 3.1e-13 0.04 0.00 1.00 FALSE
6 GTEx Artery Aorta CCDC91 0.16 0.00 enet 37 0.02 4.1e-02 -12.0 -7.5 4.8e-14 0.55 0.08 0.79 FALSE
7 GTEx Artery Aorta RP11-967K21.1 0.07 0.02 lasso 7 0.01 7.9e-02 4.5 9.1 6.9e-20 -0.85 0.05 0.85 FALSE
8 GTEx Artery Aorta RP11-996F15.2 0.35 0.28 lasso 4 0.28 1.5e-15 7.3 7.1 1.3e-12 0.04 0.00 1.00 FALSE
9 GTEx Artery Coronary RP11-996F15.2 0.54 0.44 enet 20 0.43 9.0e-16 7.3 6.1 8.1e-10 0.05 0.00 1.00 FALSE
10 GTEx Artery Tibial RP11-996F15.2 0.44 0.40 enet 28 0.44 1.2e-37 7.3 7.2 8.5e-13 0.06 0.00 1.00 FALSE
11 GTEx Brain Cerebellar Hemisphere RP11-996F15.2 0.30 0.11 enet 24 0.17 3.7e-05 7.3 6.6 4.5e-11 0.04 0.01 0.98 FALSE
12 GTEx Brain Cerebellum RP11-996F15.2 0.25 0.15 lasso 4 0.10 7.6e-04 7.3 7.2 4.4e-13 0.04 0.01 0.94 FALSE
13 GTEx Breast Mammary Tissue RP11-996F15.2 0.45 0.35 lasso 8 0.31 1.2e-16 7.3 7.4 1.5e-13 0.05 0.00 1.00 FALSE
14 GTEx Breast Mammary Tissue (Male) RP11-996F15.2 0.52 0.28 lasso 9 0.23 4.1e-06 7.3 7.5 6.0e-14 0.05 0.00 0.98 TRUE
15 GTEx Breast Mammary Tissue (Female) RP11-996F15.2 0.42 0.38 lasso 1 0.35 3.5e-11 7.3 7.3 3.3e-13 0.04 0.00 1.00 FALSE
16 GTEx Cells EBV-transformed lymphocytes RP11-996F15.2 0.27 0.24 lasso 4 0.23 6.0e-08 7.3 7.0 2.8e-12 0.04 0.00 1.00 FALSE
17 GTEx Cells Transformed fibroblasts ERGIC2 0.12 0.03 enet 23 0.05 1.4e-04 7.3 -6.6 4.9e-11 -0.02 0.00 0.99 FALSE
18 GTEx Cells Transformed fibroblasts CCDC91 0.10 0.10 lasso 5 0.09 5.5e-07 -11.5 -11.8 5.2e-32 0.84 0.06 0.93 FALSE
19 GTEx Cells Transformed fibroblasts RP11-967K21.1 0.07 0.07 lasso 2 0.07 3.7e-06 -11.8 12.3 1.2e-34 -0.96 0.12 0.88 FALSE
20 GTEx Cells Transformed fibroblasts RP11-996F15.2 0.34 0.33 lasso 7 0.34 7.3e-26 7.3 7.1 1.6e-12 0.04 0.00 1.00 FALSE
21 GTEx Colon Sigmoid RP11-996F15.2 0.42 0.27 lasso 7 0.29 7.7e-11 7.3 6.7 2.4e-11 0.05 0.00 1.00 FALSE
22 GTEx Colon Transverse CCDC91 0.11 0.01 lasso 6 0.00 4.6e-01 -11.6 -9.6 1.1e-21 0.81 0.07 0.80 FALSE
23 GTEx Colon Transverse RP11-996F15.2 0.31 0.32 lasso 1 0.31 3.5e-15 7.3 7.3 3.3e-13 0.04 0.00 1.00 FALSE
24 GTEx Esophagus Gastroesophageal Junction RP11-996F15.2 0.50 0.42 lasso 8 0.42 1.4e-16 7.3 7.1 1.1e-12 0.05 0.00 1.00 FALSE
25 GTEx Esophagus Mucosa CCDC91 0.18 0.04 enet 36 0.03 3.1e-03 4.5 -7.3 2.0e-13 0.57 0.09 0.79 FALSE
26 GTEx Esophagus Mucosa RP11-996F15.2 0.39 0.43 lasso 7 0.45 6.2e-33 7.3 7.2 4.8e-13 0.05 0.00 1.00 FALSE
27 GTEx Esophagus Muscularis RP11-996F15.2 0.56 0.45 enet 31 0.47 1.3e-31 7.3 7.0 2.5e-12 0.02 0.00 1.00 FALSE
28 GTEx Heart Atrial Appendage CCDC91 0.10 0.06 lasso 8 0.04 4.4e-03 -11.5 -11.8 3.9e-32 0.84 0.08 0.83 FALSE
29 GTEx Heart Atrial Appendage RP11-967K21.1 0.08 0.09 lasso 1 0.08 2.3e-04 -11.8 11.8 3.4e-32 -0.92 0.08 0.84 FALSE
30 GTEx Lung CCDC91 0.14 0.00 enet 33 0.06 1.5e-05 -6.6 -5.9 3.7e-09 0.37 0.25 0.20 FALSE
31 GTEx Lung RP11-996F15.2 0.50 0.46 lasso 5 0.46 1.9e-39 7.3 7.2 6.2e-13 0.04 0.00 1.00 FALSE
32 GTEx Muscle Skeletal RP11-967K21.1 0.04 0.01 lasso 9 0.00 2.9e-01 -11.6 11.0 4.4e-28 -0.88 0.07 0.79 FALSE
33 GTEx Muscle Skeletal RP11-996F15.2 0.24 0.26 lasso 11 0.25 9.3e-25 7.3 7.2 4.9e-13 0.05 0.00 1.00 FALSE
34 GTEx Nerve Tibial RP11-996F15.2 0.52 0.53 lasso 5 0.56 3.3e-47 7.3 7.0 3.2e-12 0.05 0.00 1.00 FALSE
35 GTEx Ovary RP11-996F15.2 0.50 0.46 enet 22 0.54 1.1e-15 6.3 6.4 1.6e-10 0.06 0.01 0.99 FALSE
36 GTEx Pancreas RP11-996F15.2 0.56 0.46 enet 22 0.48 1.8e-22 7.3 7.2 4.8e-13 0.03 0.00 1.00 FALSE
37 GTEx Pituitary RP11-967K21.1 0.20 0.04 lasso 7 0.04 4.4e-02 3.4 8.3 1.2e-16 -0.64 0.06 0.54 FALSE
38 GTEx Pituitary RP11-996F15.2 0.54 0.42 lasso 8 0.32 7.7e-09 7.3 7.0 2.0e-12 0.05 0.00 1.00 FALSE
39 GTEx Prostate RP11-996F15.2 0.49 0.36 enet 32 0.39 6.0e-11 7.3 7.0 2.8e-12 0.04 0.00 1.00 FALSE
40 GTEx Skin Not Sun Exposed Suprapubic CCDC91 0.26 0.05 lasso 15 0.04 4.1e-03 -12.1 -12.8 1.1e-37 0.85 0.07 0.93 TRUE
41 GTEx Skin Not Sun Exposed Suprapubic RP11-996F15.2 0.44 0.28 enet 55 0.28 1.1e-15 7.3 7.0 3.4e-12 0.02 0.00 1.00 FALSE
42 GTEx Skin Sun Exposed Lower leg CCDC91 0.09 0.01 enet 8 0.01 2.6e-02 -11.8 -11.6 4.7e-31 0.87 0.07 0.88 FALSE
43 GTEx Skin Sun Exposed Lower leg RP11-996F15.2 0.50 0.48 enet 21 0.50 1.5e-47 7.3 7.2 8.3e-13 0.04 0.00 1.00 FALSE
44 GTEx Small Intestine Terminal Ileum RP11-996F15.2 0.60 0.51 lasso 5 0.46 7.1e-12 7.3 7.3 2.1e-13 0.04 0.00 1.00 FALSE
45 GTEx Spleen RP11-996F15.2 0.53 0.49 lasso 5 0.46 1.7e-13 7.3 7.0 1.8e-12 0.06 0.00 1.00 FALSE
46 GTEx Stomach RP11-996F15.2 0.35 0.41 lasso 3 0.40 1.4e-20 7.3 7.2 5.5e-13 0.03 0.00 1.00 FALSE
47 GTEx Testis RP11-996F15.2 0.28 0.35 lasso 2 0.37 2.7e-17 7.3 7.1 1.3e-12 0.03 0.00 1.00 FALSE
48 GTEx Thyroid CCDC91 0.15 0.12 enet 42 0.12 2.9e-09 -12.0 -8.7 4.7e-18 0.83 0.06 0.94 FALSE
49 GTEx Thyroid RP11-996F15.2 0.54 0.54 lasso 8 0.55 9.1e-50 7.3 7.2 7.0e-13 0.04 0.00 1.00 FALSE
50 GTEx Vagina RP11-996F15.2 0.44 0.31 enet 23 0.27 5.9e-07 7.3 6.4 1.9e-10 0.05 0.00 0.99 FALSE
51 GTEx Whole Blood RP11-996F15.2 0.20 0.18 enet 11 0.18 9.2e-17 7.3 7.3 3.2e-13 0.07 0.00 1.00 FALSE
52 NTR Blood CCDC91 0.01 0.01 blup 648 0.00 9.0e-03 2.4 -8.3 8.7e-17 0.77 0.18 0.58 FALSE
53 ROSMAP Brain Pre-frontal Cortex RP11-996F15.2 0.21 0.22 lasso 7 0.24 5.1e-30 7.3 7.1 1.7e-12 0.05 0.00 1.00 FALSE
54 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC91 0.04 0.04 lasso 3 0.03 1.8e-06 -11.8 -11.8 2.9e-32 0.98 0.09 0.91 FALSE
55 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC91 0.06 0.02 blup 174 0.04 2.9e-05 3.2 -9.0 1.9e-19 0.82 0.33 0.65 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ERGIC2 0.04 0.03 lasso 2 0.03 1.3e-04 7.3 -7.2 5.4e-13 -0.03 0.00 0.99 FALSE
57 The Cancer Genome Atlas Brain Lower Grade Glioma ERGIC2 0.06 0.02 enet 9 0.04 4.8e-05 3.8 -5.3 8.8e-08 -0.08 0.01 0.91 FALSE
58 The Cancer Genome Atlas Lung Adenocarcinoma CCDC91 0.09 0.01 blup 170 0.02 1.0e-03 -12.0 -9.9 3.0e-23 0.80 0.07 0.87 FALSE
59 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC91 0.09 0.11 lasso 2 0.12 2.3e-05 -12.1 -12.1 8.4e-34 1.00 0.03 0.96 FALSE
60 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC91 0.22 0.00 enet 16 0.04 2.5e-05 8.0 -6.9 3.9e-12 0.44 0.02 0.12 FALSE
61 The Cancer Genome Atlas Thyroid Carcinoma CCDC91 0.40 0.12 blup 175 0.14 4.9e-13 -11.9 -9.8 1.8e-22 0.65 0.08 0.92 FALSE
62 The Cancer Genome Atlas Thyroid Carcinoma ERGIC2 0.19 0.10 blup 62 0.11 1.1e-10 6.3 -6.9 6.1e-12 -0.04 0.01 0.99 FALSE