Best TWAS P=1.09e-09 · Best GWAS P=8.03e-11 conditioned to 0.00507
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | SMOC1 | 0.14 | 0.12 | enet | 11 | 0.09 | 6.8e-06 | 4.4 | -5.5 | 4.6e-08 | -0.57 | 0.23 | 0.74 | FALSE |
| 2 | GTEx | Artery Coronary | SMOC1 | 0.24 | 0.33 | lasso | 2 | 0.32 | 1.9e-11 | -5.6 | -5.6 | 1.7e-08 | -0.57 | 0.43 | 0.57 | FALSE |
| 3 | GTEx | Artery Tibial | SMOC1 | 0.33 | 0.32 | lasso | 10 | 0.33 | 3.0e-26 | -5.6 | -5.8 | 8.3e-09 | -0.57 | 0.43 | 0.56 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SMOC1 | 0.07 | 0.00 | blup | 188 | 0.02 | 1.9e-02 | 6.5 | -6.1 | 1.1e-09 | -0.78 | 0.01 | 0.83 | TRUE |