[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr14:91,550,891-93,268,359

Best TWAS P=2.7e-19 · Best GWAS P=1.77e-18 conditioned to 0.036

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
71	METSIM	Adipose	TRIP11	0.05	0.04	enet	13	0.02	3.8e-04	-8.7	-9.0	2.7e-19	0.88	0.00	1.00	TRUE
70	METSIM	Adipose	TC2N	0.08	0.05	enet	23	0.05	3.4e-08	-5.1	5.7	9.0e-09	0.24	0.96	0.03	TRUE
12	GTEx	Artery Tibial	RP11-529H20.5	0.07	0.00	lasso	4	0.00	4.7e-01	-8.8	-8.6	9.0e-18	0.99	0.02	0.90	FALSE
56	GTEx	Spleen	RP11-529H20.5	0.31	0.15	lasso	3	0.18	2.3e-05	-7.7	-7.9	3.4e-15	0.84	0.08	0.55	FALSE
68	GTEx	Whole Blood	RP11-529H20.5	0.13	0.09	lasso	5	0.08	1.2e-07	-7.7	-7.6	2.1e-14	0.86	0.15	0.85	FALSE
80	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TRIP11	0.14	0.04	blup	70	0.09	1.6e-03	-6.4	-7.6	2.8e-14	0.88	0.03	0.60	FALSE
30	GTEx	Esophagus Mucosa	RP11-529H20.6	0.13	0.11	lasso	10	0.13	7.9e-09	-6.3	-7.5	4.5e-14	0.84	0.09	0.91	FALSE
39	GTEx	Lung	RP11-529H20.6	0.08	0.05	enet	15	0.05	1.8e-04	-6.3	-7.5	4.6e-14	0.83	0.48	0.48	FALSE
75	The Cancer Genome Atlas	Colon Adenocarcinoma	TRIP11	0.04	0.01	blup	70	0.01	4.4e-02	6.6	-7.5	5.3e-14	0.81	0.03	0.50	FALSE
2	GTEx	Adipose Subcutaneous	RP11-529H20.5	0.14	0.16	lasso	3	0.15	3.0e-12	-6.5	-7.5	5.7e-14	0.82	0.55	0.45	FALSE
62	GTEx	Testis	RP11-529H20.5	0.19	0.05	lasso	10	0.05	4.2e-03	-6.5	-7.5	5.9e-14	0.82	0.05	0.93	FALSE
11	GTEx	Artery Tibial	ATXN3	0.13	0.11	lasso	3	0.10	5.8e-08	-7.4	-7.4	1.5e-13	0.82	0.89	0.11	FALSE
18	GTEx	Breast Mammary Tissue (Female)	ATXN3	0.18	0.04	lasso	4	0.03	3.3e-02	-7.4	-7.3	2.4e-13	0.81	0.13	0.73	FALSE
69	GTEx	Whole Blood	RP11-529H20.6	0.15	0.13	lasso	4	0.16	3.8e-14	-6.3	-7.3	4.1e-13	0.80	0.58	0.42	FALSE
51	GTEx	Pituitary	RP11-529H20.5	0.37	0.14	enet	7	0.07	6.3e-03	-7.7	-7.1	1.6e-12	0.80	0.17	0.36	FALSE
31	GTEx	Esophagus Muscularis	ATXN3	0.16	0.17	lasso	5	0.17	2.0e-10	-6.5	-7.0	2.6e-12	0.77	0.99	0.01	FALSE
37	GTEx	Heart Left Ventricle	RP11-529H20.5	0.10	0.03	enet	8	0.06	2.7e-04	-7.7	-6.9	5.8e-12	0.80	0.02	0.94	FALSE
22	GTEx	Cells Transformed fibroblasts	TRIP11	0.09	0.04	lasso	2	0.00	3.8e-01	-6.5	-6.8	1.0e-11	0.67	0.24	0.03	FALSE
33	GTEx	Esophagus Muscularis	RP11-529H20.5	0.17	0.11	enet	19	0.11	2.9e-07	-6.5	-6.8	1.0e-11	0.73	0.76	0.24	FALSE
58	GTEx	Stomach	ATXN3	0.24	0.09	lasso	3	0.11	5.0e-06	-6.3	-6.8	1.3e-11	0.75	0.88	0.11	FALSE
5	GTEx	Adipose Visceral Omentum	RP11-529H20.5	0.19	0.05	lasso	6	0.08	9.9e-05	-6.3	-6.7	1.5e-11	0.79	0.32	0.68	FALSE
40	GTEx	Muscle Skeletal	ATXN3	0.04	0.04	lasso	5	0.04	1.2e-04	-6.5	-6.7	1.8e-11	0.73	0.38	0.52	FALSE
49	GTEx	Ovary	RP11-529H20.6	0.20	0.23	lasso	4	0.18	4.3e-05	-6.3	-6.7	1.8e-11	0.74	0.06	0.84	FALSE
53	GTEx	Prostate	RP11-529H20.6	0.28	0.00	lasso	5	0.05	2.5e-02	-6.3	-6.7	1.9e-11	0.58	0.15	0.09	FALSE
50	GTEx	Pituitary	ATXN3	0.33	0.03	lasso	2	0.03	4.7e-02	-6.3	-6.6	3.2e-11	0.73	0.25	0.14	FALSE
27	GTEx	Esophagus Gastroesophageal Junction	TRIP11	0.16	0.13	lasso	11	0.12	3.7e-05	-7.4	-6.6	3.9e-11	0.75	0.49	0.25	FALSE
15	GTEx	Breast Mammary Tissue	ATXN3	0.20	0.24	lasso	8	0.23	3.5e-12	-6.3	-6.5	5.8e-11	0.72	0.95	0.05	FALSE
21	GTEx	Cells Transformed fibroblasts	ATXN3	0.14	0.10	lasso	9	0.09	6.0e-07	-6.5	-6.5	6.5e-11	0.69	1.00	0.00	FALSE
63	GTEx	Testis	RP11-529H20.6	0.23	0.23	lasso	3	0.22	4.9e-10	-6.3	-6.5	6.6e-11	0.68	0.95	0.05	FALSE
73	YFS	Blood	TRIP11	0.06	0.04	blup	510	0.04	4.4e-14	-7.4	-6.5	7.0e-11	0.70	0.64	0.36	FALSE
38	GTEx	Heart Left Ventricle	RP11-529H20.6	0.13	0.12	enet	14	0.12	3.4e-07	-6.3	-6.5	7.2e-11	0.74	0.79	0.20	FALSE
45	GTEx	Nerve Tibial	RP11-529H20.5	0.28	0.26	lasso	5	0.25	9.2e-18	-6.5	-6.5	7.8e-11	0.71	1.00	0.00	FALSE
24	GTEx	Cells Transformed fibroblasts	RP11-529H20.6	0.27	0.26	lasso	6	0.24	3.1e-18	-6.3	-6.5	8.4e-11	0.71	1.00	0.00	FALSE
44	GTEx	Nerve Tibial	TRIP11	0.21	0.14	lasso	6	0.11	3.7e-08	-6.5	-6.5	9.1e-11	0.70	1.00	0.00	FALSE
34	GTEx	Esophagus Muscularis	RP11-529H20.6	0.21	0.24	lasso	2	0.22	9.2e-14	-6.5	-6.5	9.6e-11	0.69	1.00	0.00	FALSE
1	GTEx	Adipose Subcutaneous	ATXN3	0.19	0.17	lasso	5	0.17	1.7e-13	-6.5	-6.5	9.9e-11	0.70	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	ATXN3	0.19	0.14	lasso	6	0.12	7.0e-07	-6.3	-6.5	9.9e-11	0.69	0.66	0.34	FALSE
23	GTEx	Cells Transformed fibroblasts	RP11-529H20.5	0.10	0.13	lasso	11	0.12	3.1e-09	-6.5	-6.4	1.2e-10	0.69	1.00	0.00	FALSE
8	GTEx	Artery Aorta	RP11-529H20.6	0.20	0.14	lasso	4	0.18	6.4e-10	-6.3	-6.4	1.4e-10	0.70	0.96	0.02	FALSE
47	GTEx	Ovary	ATXN3	0.32	0.18	lasso	8	0.18	2.9e-05	-6.5	-6.4	1.4e-10	0.69	0.14	0.71	FALSE
46	GTEx	Nerve Tibial	RP11-529H20.6	0.29	0.30	lasso	4	0.29	4.4e-21	-6.5	-6.4	1.5e-10	0.69	1.00	0.00	FALSE
61	GTEx	Testis	TRIP11	0.10	0.05	lasso	4	0.02	3.5e-02	-6.5	-6.4	1.5e-10	0.70	0.09	0.74	FALSE
67	GTEx	Thyroid	RP11-529H20.6	0.17	0.18	lasso	2	0.17	9.6e-13	-6.3	-6.4	1.9e-10	0.70	1.00	0.00	FALSE
48	GTEx	Ovary	RP11-529H20.5	0.24	0.10	lasso	5	0.11	1.2e-03	-6.5	-6.4	2.0e-10	0.72	0.05	0.81	FALSE
60	GTEx	Stomach	RP11-529H20.6	0.20	0.27	lasso	4	0.25	2.5e-12	-6.5	-6.4	2.0e-10	0.70	1.00	0.00	FALSE
6	GTEx	Adipose Visceral Omentum	RP11-529H20.6	0.26	0.29	lasso	4	0.28	1.1e-14	-6.5	-6.4	2.1e-10	0.70	1.00	0.00	FALSE
78	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TRIP11	0.16	0.16	lasso	12	0.15	4.4e-06	-7.4	-6.4	2.1e-10	0.68	0.33	0.56	FALSE
54	GTEx	Small Intestine Terminal Ileum	RP11-529H20.6	0.36	0.32	lasso	8	0.26	1.8e-06	-6.5	-6.3	2.3e-10	0.67	0.53	0.36	FALSE
13	GTEx	Artery Tibial	RP11-529H20.6	0.20	0.22	lasso	8	0.22	2.3e-17	-6.3	-6.3	2.7e-10	0.69	1.00	0.00	FALSE
76	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIP11	0.02	0.02	lasso	1	0.01	1.1e-02	-6.3	-6.3	2.9e-10	0.69	0.14	0.11	FALSE
3	GTEx	Adipose Subcutaneous	RP11-529H20.6	0.16	0.26	lasso	2	0.26	4.8e-21	-6.3	-6.3	3.1e-10	0.69	1.00	0.00	FALSE
35	GTEx	Heart Atrial Appendage	RP11-529H20.6	0.27	0.20	lasso	5	0.18	2.5e-08	-6.3	-6.3	3.3e-10	0.68	0.99	0.01	FALSE
42	GTEx	Muscle Skeletal	RP11-529H20.6	0.11	0.06	lasso	2	0.06	2.9e-06	-6.3	-6.3	3.8e-10	0.69	0.98	0.01	FALSE
43	GTEx	Nerve Tibial	ATXN3	0.30	0.29	lasso	4	0.29	1.6e-20	-6.5	-6.2	4.9e-10	0.70	1.00	0.00	FALSE
17	GTEx	Breast Mammary Tissue	RP11-529H20.6	0.20	0.23	enet	13	0.27	3.5e-14	-6.3	-6.2	5.3e-10	0.72	0.97	0.03	FALSE
41	GTEx	Muscle Skeletal	TRIP11	0.05	0.04	lasso	6	0.03	7.9e-04	-6.4	-6.2	5.4e-10	0.69	0.39	0.42	FALSE
14	GTEx	Brain Putamen basal ganglia	RP11-529H20.6	0.44	0.14	enet	45	0.26	6.1e-07	-8.7	-6.2	6.2e-10	0.83	0.02	0.97	FALSE
20	GTEx	Cells EBV-transformed lymphocytes	RP11-529H20.6	0.41	0.30	lasso	2	0.28	6.9e-10	-6.3	-6.1	1.3e-09	0.68	0.98	0.02	FALSE
66	GTEx	Thyroid	RP11-529H20.5	0.14	0.12	enet	14	0.13	7.7e-10	-7.7	-6.1	1.3e-09	0.70	0.17	0.83	FALSE
9	GTEx	Artery Coronary	ATXN3	0.21	0.20	lasso	2	0.24	1.4e-08	-6.3	-6.0	1.7e-09	0.61	0.62	0.32	FALSE
16	GTEx	Breast Mammary Tissue	RP11-529H20.5	0.22	0.10	enet	23	0.12	1.1e-06	-6.3	-6.0	2.0e-09	0.74	0.26	0.74	FALSE
7	GTEx	Adrenal Gland	RP11-529H20.6	0.22	0.21	lasso	7	0.18	4.8e-07	-6.5	-6.0	2.6e-09	0.68	0.85	0.08	FALSE
59	GTEx	Stomach	RP11-529H20.5	0.19	0.12	enet	32	0.12	2.2e-06	-6.3	-5.9	3.4e-09	0.72	0.20	0.79	FALSE
55	GTEx	Spleen	ATXN3	0.27	0.03	lasso	3	0.01	1.5e-01	-6.5	-5.9	3.5e-09	0.67	0.06	0.63	FALSE
26	GTEx	Colon Sigmoid	RP11-529H20.6	0.24	0.24	lasso	3	0.27	4.8e-10	-6.3	-5.9	4.3e-09	0.69	1.00	0.00	FALSE
32	GTEx	Esophagus Muscularis	TRIP11	0.10	0.11	lasso	4	0.10	8.3e-07	-6.5	-5.9	4.3e-09	0.68	0.62	0.38	FALSE
29	GTEx	Esophagus Mucosa	TRIP11	0.09	0.01	lasso	4	0.00	2.4e-01	-6.5	-5.8	6.3e-09	0.71	0.12	0.28	FALSE
77	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TC2N	0.17	0.12	blup	83	0.12	2.1e-05	-5.1	5.7	1.1e-08	0.05	0.37	0.19	FALSE
52	GTEx	Prostate	TRIP11	0.42	-0.01	enet	79	0.05	1.8e-02	-8.7	-5.7	1.2e-08	0.31	0.03	0.65	FALSE
72	YFS	Blood	ATXN3	0.20	0.14	enet	52	0.24	1.1e-75	-6.5	-5.7	1.2e-08	0.79	1.00	0.00	FALSE
28	GTEx	Esophagus Gastroesophageal Junction	RP11-529H20.6	0.26	0.27	enet	26	0.26	6.2e-10	-6.5	-5.6	1.7e-08	0.70	0.99	0.01	FALSE
19	GTEx	Breast Mammary Tissue (Female)	RP11-529H20.6	0.22	0.13	lasso	3	0.09	1.5e-03	-6.3	-5.6	1.8e-08	0.68	0.17	0.79	FALSE
79	The Cancer Genome Atlas	Thyroid Carcinoma	TRIP11	0.08	0.04	blup	70	0.06	3.6e-06	-5.3	-5.6	2.1e-08	0.70	0.39	0.57	FALSE
65	GTEx	Thyroid	TRIP11	0.08	0.04	lasso	4	0.02	6.3e-03	-6.4	-5.5	3.5e-08	0.67	0.44	0.19	FALSE
36	GTEx	Heart Left Ventricle	TC2N	0.13	0.10	enet	15	0.10	6.5e-06	4.8	5.5	4.4e-08	0.11	0.88	0.02	FALSE
57	GTEx	Spleen	RP11-529H20.6	0.53	0.22	enet	40	0.32	6.2e-09	-6.5	-5.5	5.0e-08	0.65	0.33	0.66	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	FBLN5	0.05	0.01	lasso	3	0.02	1.2e-04	2.8	5.4	8.4e-08	-0.24	0.34	0.03	FALSE
10	GTEx	Artery Coronary	TRIP11	0.18	0.01	lasso	3	0.00	3.2e-01	-6.5	-5.3	1.4e-07	0.72	0.09	0.23	FALSE
64	GTEx	Thyroid	ATXN3	0.13	0.05	enet	11	0.14	5.5e-11	-6.3	-5.3	1.5e-07	0.67	0.13	0.87	FALSE
25	GTEx	Colon Sigmoid	ATXN3	0.31	0.30	lasso	2	0.33	3.4e-12	-6.3	-5.1	2.7e-07	0.66	1.00	0.00	FALSE