[Hub]/) : Traits : Comparative height size at age 10 :

chr14:103,161,201-105,211,221

Best TWAS P=3.3e-16 · Best GWAS P=1.86e-17 conditioned to 0.384

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous KLC1 0.05 0.03 lasso 3 0.03 1.8e-03 -5.8 -5.8 6.5e-09 0.73 0.16 0.47 FALSE
2 GTEx Adipose Subcutaneous XRCC3 0.09 0.08 lasso 5 0.07 3.8e-06 -5.9 -5.4 6.2e-08 0.61 0.95 0.05 FALSE
3 GTEx Adrenal Gland CKB 0.18 0.00 enet 16 0.02 6.9e-02 -4.1 -5.6 2.2e-08 0.37 0.06 0.20 FALSE
4 GTEx Brain Cortex XRCC3 0.12 0.02 lasso 4 0.01 1.7e-01 -2.6 -5.7 1.1e-08 0.72 0.04 0.78 FALSE
5 GTEx Brain Frontal Cortex BA9 APOPT1 0.17 0.07 lasso 3 0.08 4.6e-03 -8.4 7.4 1.8e-13 -0.93 0.03 0.84 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia RP11-73M18.8 0.12 0.03 lasso 4 0.01 1.4e-01 2.9 -5.5 3.2e-08 0.53 0.06 0.26 FALSE
7 GTEx Breast Mammary Tissue KLC1 0.12 0.02 enet 26 0.07 2.9e-04 -2.5 -5.3 1.1e-07 0.68 0.32 0.63 FALSE
8 GTEx Colon Transverse KLC1 0.16 0.01 lasso 7 0.00 1.9e-01 -5.9 -6.4 1.4e-10 0.70 0.08 0.53 FALSE
9 GTEx Colon Transverse BAG5 0.14 0.05 lasso 10 0.02 4.8e-02 -6.3 -5.7 1.2e-08 0.58 0.19 0.41 FALSE
10 GTEx Esophagus Mucosa MARK3 0.11 0.03 lasso 4 0.04 1.5e-03 4.5 7.3 3.6e-13 -0.77 0.02 0.93 FALSE
11 GTEx Esophagus Muscularis APOPT1 0.16 0.02 enet 11 0.04 2.2e-03 5.4 6.0 1.7e-09 -0.53 0.07 0.73 FALSE
12 GTEx Nerve Tibial APOPT1 0.10 0.08 lasso 5 0.06 7.8e-05 -5.9 5.2 1.6e-07 -0.61 0.66 0.18 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic RP11-73M18.8 0.10 0.01 lasso 6 0.02 3.8e-02 -7.2 -5.3 8.9e-08 0.59 0.12 0.62 FALSE
14 GTEx Spleen KLC1 0.15 0.05 lasso 3 0.03 6.4e-02 -8.4 -7.7 1.1e-14 0.92 0.04 0.63 FALSE
15 GTEx Thyroid APOPT1 0.11 0.12 lasso 1 0.10 1.9e-08 -5.9 5.9 3.5e-09 -0.65 1.00 0.00 FALSE
16 METSIM Adipose MARK3 0.03 0.02 lasso 6 0.03 6.3e-05 -5.9 5.7 9.5e-09 -0.81 0.02 0.98 TRUE
17 METSIM Adipose TDRD9 0.08 0.04 lasso 10 0.06 1.9e-09 -5.9 7.2 7.7e-13 -0.56 0.44 0.56 FALSE
18 NTR Blood KLC1 0.04 0.02 blup 393 0.04 8.2e-12 -4.1 -5.2 1.6e-07 0.55 0.99 0.01 FALSE
19 YFS Blood CKB 0.03 0.02 lasso 4 0.02 6.6e-07 5.4 -6.3 3.1e-10 0.40 0.94 0.05 FALSE
20 YFS Blood TRMT61A 0.08 0.11 lasso 4 0.12 1.6e-37 -7.2 -6.7 2.3e-11 0.71 1.00 0.00 FALSE
21 The Cancer Genome Atlas Glioblastoma Multiforme MARK3 0.12 0.05 blup 64 0.07 3.3e-03 4.2 5.6 1.9e-08 -0.64 0.02 0.23 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma C14orf153 0.04 0.01 blup 38 0.03 6.2e-04 -5.8 6.2 7.6e-10 -0.73 0.07 0.37 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma C14orf153 0.06 0.02 blup 38 0.04 2.4e-05 2.3 5.7 1.1e-08 -0.69 0.16 0.42 FALSE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CKB 0.03 0.00 blup 34 0.02 1.4e-03 -5.9 6.0 2.6e-09 -0.80 0.03 0.52 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma CKB 0.07 0.09 blup 32 0.10 1.1e-10 -8.4 8.2 3.3e-16 -0.93 0.01 0.99 TRUE
26 The Cancer Genome Atlas Stomach Adenocarcinoma C14orf153 0.20 0.05 lasso 2 0.04 8.8e-04 -8.4 7.8 5.4e-15 -0.95 0.00 0.98 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma KLC1 0.04 0.01 blup 82 0.03 5.4e-04 -5.9 -5.3 1.2e-07 0.67 0.04 0.74 FALSE