[Hub]/) : Traits : Comparative height size at age 10 :

chr16:52,772,129-54,235,440

Best TWAS P=3.5e-16 · Best GWAS P=3.99e-16 conditioned to 0.0273

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RBL2 0.22 0.24 enet 15 0.26 1.8e-31 5.4 -6.8 1.3e-11 -0.86 0.80 0.20 FALSE
2 GTEx Adipose Subcutaneous RBL2 0.34 0.28 enet 18 0.30 1.0e-24 5.6 -5.8 6.4e-09 -0.74 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum RBL2 0.30 0.27 lasso 2 0.27 4.3e-14 5.6 -5.6 2.3e-08 -0.69 1.00 0.00 FALSE
4 GTEx Adrenal Gland RBL2 0.35 0.27 enet 22 0.25 2.3e-09 5.6 -5.1 2.7e-07 -0.67 0.94 0.06 FALSE
5 GTEx Artery Aorta RBL2 0.27 0.21 enet 14 0.19 1.5e-10 5.4 -5.5 4.6e-08 -0.69 1.00 0.00 FALSE
6 GTEx Artery Coronary RBL2 0.36 0.33 enet 14 0.27 1.4e-09 5.6 -5.3 9.6e-08 -0.68 0.98 0.02 FALSE
7 GTEx Artery Tibial RBL2 0.16 0.17 enet 11 0.20 2.1e-15 5.4 -6.6 3.7e-11 -0.83 0.55 0.45 FALSE
8 GTEx Brain Cerebellar Hemisphere RBL2 0.55 0.55 enet 20 0.46 2.1e-13 5.6 -5.8 7.2e-09 -0.70 0.97 0.03 FALSE
9 GTEx Brain Cerebellum RBL2 0.66 0.72 enet 16 0.70 5.7e-28 5.6 -5.7 1.3e-08 -0.71 1.00 0.00 FALSE
10 GTEx Brain Cortex RBL2 0.51 0.45 enet 12 0.46 3.5e-14 4.9 -6.1 9.0e-10 -0.80 0.30 0.70 FALSE
11 GTEx Breast Mammary Tissue RBL2 0.36 0.35 lasso 3 0.36 3.0e-19 5.4 -5.3 8.7e-08 -0.68 1.00 0.00 FALSE
12 GTEx Breast Mammary Tissue (Male) RBL2 0.40 0.29 lasso 2 0.25 1.4e-06 5.4 -5.4 7.4e-08 -0.68 0.48 0.23 FALSE
13 GTEx Colon Sigmoid RBL2 0.38 0.37 lasso 12 0.29 8.4e-11 5.6 -6.3 2.4e-10 -0.79 0.57 0.43 FALSE
14 GTEx Colon Transverse RBL2 0.59 0.44 enet 13 0.52 4.4e-28 5.6 -5.6 2.4e-08 -0.75 1.00 0.00 FALSE
15 GTEx Esophagus Gastroesophageal Junction RBL2 0.38 0.40 enet 17 0.38 1.1e-14 5.6 -5.4 5.4e-08 -0.69 1.00 0.00 FALSE
16 GTEx Esophagus Mucosa RBL2 0.36 0.36 enet 37 0.37 2.9e-26 5.6 -6.3 3.6e-10 -0.78 1.00 0.00 FALSE
17 GTEx Esophagus Muscularis RBL2 0.36 0.38 enet 10 0.41 6.8e-27 5.6 -5.4 5.3e-08 -0.68 1.00 0.00 FALSE
18 GTEx Heart Atrial Appendage RBL2 0.28 0.14 enet 25 0.23 8.6e-11 5.4 -5.9 3.7e-09 -0.76 0.11 0.89 FALSE
19 GTEx Heart Left Ventricle RBL2 0.12 0.11 enet 12 0.08 3.3e-05 5.4 -5.6 2.5e-08 -0.62 0.70 0.25 FALSE
20 GTEx Lung RBL2 0.29 0.37 enet 16 0.35 9.1e-28 5.6 -5.8 5.8e-09 -0.73 1.00 0.00 FALSE
21 GTEx Muscle Skeletal RBL2 0.11 0.00 lasso 5 0.00 2.9e-01 7.5 -8.2 3.5e-16 -0.86 0.02 0.96 TRUE
22 GTEx Nerve Tibial RBL2 0.46 0.52 enet 19 0.53 1.6e-43 5.4 -5.9 3.3e-09 -0.74 1.00 0.00 FALSE
23 GTEx Pancreas RBL2 0.36 0.36 enet 26 0.36 5.9e-16 5.6 -6.3 3.6e-10 -0.78 0.84 0.16 FALSE
24 GTEx Pituitary RBL2 0.36 0.39 lasso 6 0.40 4.5e-11 5.6 5.7 1.0e-08 0.68 0.73 0.26 FALSE
25 GTEx Prostate RBL2 0.55 0.45 lasso 4 0.45 1.0e-12 5.4 -5.7 1.5e-08 -0.69 0.96 0.03 FALSE
26 GTEx Skin Not Sun Exposed Suprapubic RBL2 0.35 0.33 enet 16 0.34 2.6e-19 5.4 -5.7 1.1e-08 -0.74 1.00 0.00 FALSE
27 GTEx Skin Sun Exposed Lower leg RBL2 0.35 0.39 enet 25 0.37 2.9e-32 5.4 -6.1 1.3e-09 -0.72 1.00 0.00 FALSE
28 GTEx Spleen RBL2 0.59 0.47 enet 51 0.46 3.2e-13 5.6 -6.3 3.7e-10 -0.65 0.39 0.61 FALSE
29 GTEx Stomach RBL2 0.33 0.26 enet 20 0.26 8.7e-13 5.6 -5.4 6.1e-08 -0.62 1.00 0.00 FALSE
30 GTEx Thyroid RBL2 0.34 0.47 lasso 4 0.45 3.6e-38 5.6 -5.6 1.8e-08 -0.70 1.00 0.00 FALSE
31 GTEx Vagina RBL2 0.41 0.37 enet 13 0.34 1.6e-08 5.5 -6.1 1.1e-09 -0.75 0.32 0.64 FALSE
32 NTR Blood RBL2 0.09 0.11 bslmm 419 0.11 1.1e-33 5.6 -5.4 7.9e-08 -0.68 1.00 0.00 FALSE
33 YFS Blood AKTIP 0.19 0.27 lasso 13 0.30 3.3e-99 8.1 7.2 5.1e-13 0.93 0.00 1.00 FALSE
34 The Cancer Genome Atlas Esophageal Carcinoma RBL2 0.08 0.04 lasso 3 0.03 4.4e-02 8.1 6.4 1.5e-10 0.85 0.01 0.82 FALSE
35 The Cancer Genome Atlas Brain Lower Grade Glioma RBL2 0.03 0.06 enet 5 0.05 8.2e-07 4.9 -6.1 1.1e-09 -0.78 0.82 0.18 FALSE
36 The Cancer Genome Atlas Pancreatic Adenocarcinoma RBL2 0.11 0.08 blup 44 0.06 1.5e-03 7.5 -7.1 9.5e-13 -0.91 0.01 0.78 FALSE