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chr16:66,666,637-68,853,671

Best TWAS P=8.34e-14 · Best GWAS P=1.12e-11 conditioned to 0.522

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
34	The Cancer Genome Atlas	Stomach Adenocarcinoma	AGRP	0.04	0.02	blup	23	0.03	3.0e-03	-6.7	-7.5	8.3e-14	0.87	0.01	0.74	TRUE
16	METSIM	Adipose	CTCF	0.03	0.02	bslmm	222	0.01	3.4e-03	-6.8	-7.3	3.1e-13	0.90	0.02	0.90	FALSE
18	METSIM	Adipose	RLTPR	0.04	0.00	bslmm	211	0.00	1.1e-01	-6.8	-7.0	1.9e-12	0.83	0.03	0.80	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC36	0.07	0.03	blup	39	0.03	2.5e-04	-6.4	-7.0	3.8e-12	0.86	0.06	0.94	FALSE
33	The Cancer Genome Atlas	Rectum Adenocarcinoma	LRRC36	0.13	0.12	lasso	14	0.11	1.4e-03	-6.8	-6.8	1.1e-11	1.00	0.01	0.66	FALSE
36	The Cancer Genome Atlas	Thyroid Carcinoma	LRRC36	0.04	0.04	lasso	3	0.04	1.5e-04	-6.7	-6.7	1.8e-11	0.99	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	ZDHHC1	0.07	0.06	enet	7	0.07	2.9e-07	-6.6	-6.7	1.9e-11	0.95	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZDHHC1	0.02	0.01	lasso	1	0.01	2.4e-03	-6.7	6.7	2.6e-11	-0.99	0.01	0.88	FALSE
2	GTEx	Artery Tibial	RANBP10	0.08	0.04	lasso	3	0.05	6.4e-05	-6.7	6.7	3.0e-11	-0.92	0.03	0.96	FALSE
13	GTEx	Thyroid	ZDHHC1	0.07	0.03	lasso	6	0.02	1.6e-02	-6.7	-6.6	3.2e-11	0.99	0.01	0.96	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	ZDHHC1	0.10	0.00	lasso	7	0.00	5.1e-01	-6.7	6.6	3.4e-11	-0.87	0.02	0.77	FALSE
17	METSIM	Adipose	LRRC36	0.10	0.07	lasso	24	0.10	1.6e-14	-6.8	-6.6	3.8e-11	0.95	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TPPP3	0.03	0.02	blup	31	0.04	2.1e-05	-6.8	6.6	5.1e-11	-0.92	0.02	0.98	FALSE
6	GTEx	Nerve Tibial	RANBP10	0.15	0.14	lasso	7	0.13	1.8e-09	-5.9	6.5	6.0e-11	-0.88	0.11	0.89	FALSE
4	GTEx	Esophagus Muscularis	RANBP10	0.13	0.05	lasso	4	0.02	2.3e-02	-6.7	6.5	8.1e-11	-0.88	0.03	0.96	FALSE
10	GTEx	Testis	DUS2	0.15	0.01	enet	9	0.03	1.1e-02	3.8	6.5	8.3e-11	-0.61	0.16	0.49	FALSE
12	GTEx	Thyroid	RANBP10	0.08	0.03	lasso	4	0.03	2.2e-03	-5.9	6.4	1.7e-10	-0.86	0.06	0.80	FALSE
31	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AGRP	0.11	0.01	enet	6	0.07	2.5e-05	1.7	-6.4	2.1e-10	0.64	0.01	0.56	FALSE
11	GTEx	Testis	RP11-67A1.2	0.20	0.02	lasso	6	0.09	8.3e-05	3.7	6.3	3.3e-10	-0.56	0.08	0.89	FALSE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	CENPT	0.05	0.05	enet	8	0.04	3.0e-03	-5.9	-6.2	4.7e-10	0.71	0.01	0.90	FALSE
14	GTEx	Thyroid	HSD11B2	0.15	0.07	enet	23	0.09	1.9e-07	-5.9	-6.1	8.7e-10	0.86	0.35	0.65	FALSE
5	GTEx	Muscle Skeletal	C16orf86	0.05	0.04	lasso	2	0.03	4.0e-04	-5.9	6.1	9.3e-10	-0.82	0.06	0.75	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	LRRC36	0.04	0.04	enet	8	0.05	5.8e-10	-6.2	-6.0	2.1e-09	0.73	0.18	0.82	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	C16orf86	0.04	0.04	lasso	2	0.03	3.8e-04	-6.0	6.0	2.1e-09	-0.80	0.00	0.98	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	C16orf86	0.05	0.05	lasso	1	0.04	2.9e-05	-6.0	6.0	2.5e-09	-0.80	0.00	1.00	FALSE
20	YFS	Blood	ZDHHC1	0.05	0.05	enet	26	0.05	1.8e-16	-6.4	-5.9	4.4e-09	0.85	0.05	0.95	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GFOD2	0.03	0.03	lasso	1	0.03	3.6e-04	-5.8	5.8	5.9e-09	-0.76	0.01	0.98	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	KCTD19	0.02	0.02	blup	29	0.03	3.5e-06	-6.2	-5.8	8.0e-09	0.53	0.11	0.87	FALSE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	RLTPR	0.03	0.02	lasso	3	0.02	1.8e-03	-5.4	5.7	1.0e-08	-0.79	0.00	0.88	FALSE
15	GTEx	Whole Blood	DUS2	0.12	0.04	enet	10	0.05	4.0e-05	-5.9	-5.7	1.3e-08	0.74	0.11	0.89	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	C16orf48	0.04	0.02	blup	17	0.04	8.5e-05	-6.0	5.6	2.2e-08	-0.69	0.00	0.84	FALSE
19	YFS	Blood	ATP6V0D1	0.14	0.18	lasso	15	0.20	1.8e-63	-6.4	5.6	2.3e-08	-0.92	0.04	0.96	FALSE
3	GTEx	Cells Transformed fibroblasts	RANBP10	0.10	0.01	enet	29	0.03	2.8e-03	-6.0	5.4	5.4e-08	-0.62	0.05	0.36	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	RANBP10	0.04	0.03	blup	31	0.04	6.5e-05	-5.8	5.4	6.2e-08	-0.73	0.02	0.95	FALSE
9	GTEx	Spleen	ATP6V0D1	0.36	0.03	enet	9	0.07	6.0e-03	-2.4	5.3	1.0e-07	-0.82	0.03	0.34	FALSE
1	GTEx	Adipose Subcutaneous	RANBP10	0.05	0.01	lasso	6	0.01	3.5e-02	-5.7	5.3	1.4e-07	-0.79	0.15	0.76	FALSE
7	GTEx	Pituitary	ZDHHC1	0.23	0.13	lasso	4	0.08	4.0e-03	-5.9	-5.2	2.2e-07	0.74	0.04	0.48	FALSE