[Hub]/) : Traits : Comparative height size at age 10 :

chr16:66,666,637-68,853,671

Best TWAS P=8.34e-14 · Best GWAS P=1.12e-11 conditioned to 0.522

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RANBP10 0.05 0.01 lasso 6 0.01 3.5e-02 -5.7 5.3 1.4e-07 -0.79 0.15 0.76 FALSE
2 GTEx Artery Tibial RANBP10 0.08 0.04 lasso 3 0.05 6.4e-05 -6.7 6.7 3.0e-11 -0.92 0.03 0.96 FALSE
3 GTEx Cells Transformed fibroblasts RANBP10 0.10 0.01 enet 29 0.03 2.8e-03 -6.0 5.4 5.4e-08 -0.62 0.05 0.36 FALSE
4 GTEx Esophagus Muscularis RANBP10 0.13 0.05 lasso 4 0.02 2.3e-02 -6.7 6.5 8.1e-11 -0.88 0.03 0.96 FALSE
5 GTEx Muscle Skeletal C16orf86 0.05 0.04 lasso 2 0.03 4.0e-04 -5.9 6.1 9.3e-10 -0.82 0.06 0.75 FALSE
6 GTEx Nerve Tibial RANBP10 0.15 0.14 lasso 7 0.13 1.8e-09 -5.9 6.5 6.0e-11 -0.88 0.11 0.89 FALSE
7 GTEx Pituitary ZDHHC1 0.23 0.13 lasso 4 0.08 4.0e-03 -5.9 -5.2 2.2e-07 0.74 0.04 0.48 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic ZDHHC1 0.10 0.00 lasso 7 0.00 5.1e-01 -6.7 6.6 3.4e-11 -0.87 0.02 0.77 FALSE
9 GTEx Spleen ATP6V0D1 0.36 0.03 enet 9 0.07 6.0e-03 -2.4 5.3 1.0e-07 -0.82 0.03 0.34 FALSE
10 GTEx Testis DUS2 0.15 0.01 enet 9 0.03 1.1e-02 3.8 6.5 8.3e-11 -0.61 0.16 0.49 FALSE
11 GTEx Testis RP11-67A1.2 0.20 0.02 lasso 6 0.09 8.3e-05 3.7 6.3 3.3e-10 -0.56 0.08 0.89 FALSE
12 GTEx Thyroid RANBP10 0.08 0.03 lasso 4 0.03 2.2e-03 -5.9 6.4 1.7e-10 -0.86 0.06 0.80 FALSE
13 GTEx Thyroid ZDHHC1 0.07 0.03 lasso 6 0.02 1.6e-02 -6.7 -6.6 3.2e-11 0.99 0.01 0.96 FALSE
14 GTEx Thyroid HSD11B2 0.15 0.07 enet 23 0.09 1.9e-07 -5.9 -6.1 8.7e-10 0.86 0.35 0.65 FALSE
15 GTEx Whole Blood DUS2 0.12 0.04 enet 10 0.05 4.0e-05 -5.9 -5.7 1.3e-08 0.74 0.11 0.89 FALSE
16 METSIM Adipose CTCF 0.03 0.02 bslmm 222 0.01 3.4e-03 -6.8 -7.3 3.1e-13 0.90 0.02 0.90 FALSE
17 METSIM Adipose LRRC36 0.10 0.07 lasso 24 0.10 1.6e-14 -6.8 -6.6 3.8e-11 0.95 0.02 0.98 FALSE
18 METSIM Adipose RLTPR 0.04 0.00 bslmm 211 0.00 1.1e-01 -6.8 -7.0 1.9e-12 0.83 0.03 0.80 FALSE
19 YFS Blood ATP6V0D1 0.14 0.18 lasso 15 0.20 1.8e-63 -6.4 5.6 2.3e-08 -0.92 0.04 0.96 FALSE
20 YFS Blood ZDHHC1 0.05 0.05 enet 26 0.05 1.8e-16 -6.4 -5.9 4.4e-09 0.85 0.05 0.95 FALSE
21 The Cancer Genome Atlas Breast Invasive Carcinoma KCTD19 0.02 0.02 blup 29 0.03 3.5e-06 -6.2 -5.8 8.0e-09 0.53 0.11 0.87 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma LRRC36 0.04 0.04 enet 8 0.05 5.8e-10 -6.2 -6.0 2.1e-09 0.73 0.18 0.82 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma ZDHHC1 0.02 0.01 lasso 1 0.01 2.4e-03 -6.7 6.7 2.6e-11 -0.99 0.01 0.88 FALSE
24 The Cancer Genome Atlas Colon Adenocarcinoma CENPT 0.05 0.05 enet 8 0.04 3.0e-03 -5.9 -6.2 4.7e-10 0.71 0.01 0.90 FALSE
25 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GFOD2 0.03 0.03 lasso 1 0.03 3.6e-04 -5.8 5.8 5.9e-09 -0.76 0.01 0.98 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TPPP3 0.03 0.02 blup 31 0.04 2.1e-05 -6.8 6.6 5.1e-11 -0.92 0.02 0.98 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma LRRC36 0.07 0.03 blup 39 0.03 2.5e-04 -6.4 -7.0 3.8e-12 0.86 0.06 0.94 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma RANBP10 0.04 0.03 blup 31 0.04 6.5e-05 -5.8 5.4 6.2e-08 -0.73 0.02 0.95 FALSE
29 The Cancer Genome Atlas Lung Adenocarcinoma C16orf86 0.04 0.04 lasso 2 0.03 3.8e-04 -6.0 6.0 2.1e-09 -0.80 0.00 0.98 FALSE
30 The Cancer Genome Atlas Lung Adenocarcinoma RLTPR 0.03 0.02 lasso 3 0.02 1.8e-03 -5.4 5.7 1.0e-08 -0.79 0.00 0.88 FALSE
31 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AGRP 0.11 0.01 enet 6 0.07 2.5e-05 1.7 -6.4 2.1e-10 0.64 0.01 0.56 FALSE
32 The Cancer Genome Atlas Prostate Adenocarcinoma C16orf86 0.05 0.05 lasso 1 0.04 2.9e-05 -6.0 6.0 2.5e-09 -0.80 0.00 1.00 FALSE
33 The Cancer Genome Atlas Rectum Adenocarcinoma LRRC36 0.13 0.12 lasso 14 0.11 1.4e-03 -6.8 -6.8 1.1e-11 1.00 0.01 0.66 FALSE
34 The Cancer Genome Atlas Stomach Adenocarcinoma AGRP 0.04 0.02 blup 23 0.03 3.0e-03 -6.7 -7.5 8.3e-14 0.87 0.01 0.74 TRUE
35 The Cancer Genome Atlas Thyroid Carcinoma C16orf48 0.04 0.02 blup 17 0.04 8.5e-05 -6.0 5.6 2.2e-08 -0.69 0.00 0.84 FALSE
36 The Cancer Genome Atlas Thyroid Carcinoma LRRC36 0.04 0.04 lasso 3 0.04 1.5e-04 -6.7 -6.7 1.8e-11 0.99 0.01 0.99 FALSE
37 The Cancer Genome Atlas Thyroid Carcinoma ZDHHC1 0.07 0.06 enet 7 0.07 2.9e-07 -6.6 -6.7 1.9e-11 0.95 0.02 0.98 FALSE