Hub : Genes

AKTIP

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1180 0.0290 1.0e-08 0.090 0.032 0.084 0.022 0.076 4.5e-11 7.6e-05 1.9e-10 1e-03 1.4e-09
2 GTEx Brain Frontal Cortex BA9 0.2895 0.1040 3.3e-03 0.043 NA 0.071 NA 0.037 2.7e-02 NA 6.3e-03 NA 3.7e-02
3 GTEx Testis 0.1930 0.0760 7.8e-03 0.000 NA 0.005 NA 0.002 3.1e-01 NA 1.9e-01 NA 2.4e-01
4 YFS Blood 0.1943 0.0258 0.0e+00 0.270 0.286 0.295 0.297 0.298 2.4e-88 1.5e-94 5.3e-98 6e-99 3.3e-99
5 TCGA Brain Lower Grade Glioma 0.0416 0.0191 1.5e-06 0.032 0.051 0.033 NA 0.042 1.3e-04 1.9e-06 1.1e-04 NA 1.2e-05
6 TCGA Soft Tissue Sarcoma 0.0760 0.0460 1.9e-03 0.028 0.037 0.034 NA 0.035 8.0e-03 2.9e-03 4.3e-03 NA 3.4e-03
7 TCGA Testicular Germ Cell Tumors 0.1790 0.1030 9.3e-03 -0.007 0.036 0.084 NA 0.045 7.2e-01 2.1e-02 6.9e-04 NA 1.0e-02
8 TCGA Thyroid Carcinoma 0.0750 0.0330 1.0e-04 0.016 0.017 0.023 NA 0.014 9.0e-03 7.8e-03 2.4e-03 NA 1.5e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.2 1.9 5.3 -1.3 -1.1 0.3 0.7 -1.6 -2.3 -1.3 -1.4
Bipolar Disorder or Schizophrenia 1.2 3.0 11.6 -1.4 -0.2 -0.8 0.7 -1.8 -3.4 -2.1 -1.2
Depressed Affect (Nagel 2018) 0.2 0.4 1.4 0.3 0.7 0.9 0.1 0.3 -0.1 -0.7 1.2
Depression (Nagel 2018) 0.5 0.7 3.1 0.4 0.7 1.8 -0.1 0.6 0.0 -0.2 1.2
Intelligence (Savage-Jansen 2018) 8.9 27.4 67.7 -6.5 -4.2 2.9 8.2 -6.7 -2.3 -5.2 -2.5
Neuroticism (Nagel 2018) 0.1 0.2 0.8 -0.2 -0.3 0.5 0.4 -0.1 0.9 0.3 0.3
Schizophrenia (2018) 0.7 1.5 6.2 -0.7 0.5 -1.1 0.3 -1.0 -2.5 -1.7 -0.3
Schizophrenia vs Biploar Disorder 0.5 0.7 1.6 1.1 1.3 0.3 -1.0 0.9 0.3 0.5 0.5
Worry (Nagel 2018) 0.4 0.7 2.9 -0.2 -0.6 -1.7 0.4 0.2 1.3 0.9 -0.0
Alzheimer’s Disease (in mother) 0.3 0.4 2.0 0.5 -0.0 0.2 -0.5 0.4 1.4 -0.6 0.1
Alzheimer’s Disease (in father) 1.1 1.2 3.1 0.2 0.8 0.6 -1.8 1.1 1.2 1.8 -0.2
Alzheimer’s Disease (including proxy) 0.6 0.9 3.0 0.2 -0.2 0.3 -1.2 0.9 1.7 1.2 -0.4
Crohns Disease (2017) 1.0 2.2 7.0 -0.2 0.8 2.0 2.6 -0.8 0.8 -1.6 1.5
Irritable Bowel Disease (IBD) 0.5 1.3 3.1 -0.3 0.8 1.3 1.8 -0.9 -0.0 -1.6 1.1
Ulcerative Colitis (UC) 0.1 0.1 0.4 0.1 0.6 0.1 -0.1 -0.1 -0.1 -0.6 0.3
Major Depression (MDD) 0.7 0.8 4.2 0.9 0.2 2.1 -0.3 0.9 0.3 -0.0 0.9
Reaction Time 0.4 0.8 2.6 -0.9 -1.6 -0.2 0.2 -0.5 0.6 0.6 -1.3
Verbal and Numeric Reasoning (VNR) 8.1 19.5 51.6 -5.4 -3.4 3.2 7.2 -5.6 -1.8 -3.9 -1.9
Breast Cancer 1.3 3.2 24.0 0.2 0.9 4.9 -0.7 0.6 0.3 0.1 0.1
Ovarian Cancer 1.8 2.3 5.0 -2.0 -2.1 0.2 1.3 -2.2 -1.2 -1.0 -1.2
Prostate Cancer 1.2 1.6 2.7 -1.4 -0.9 -0.8 1.2 -1.3 -1.5 -1.7 -1.3
Age at First Birth 1.8 2.6 7.6 -1.7 -2.8 -0.8 0.7 -1.1 -0.8 1.0 -2.4
Bipolar Disorder (2011) 3.6 3.5 11.8 -1.6 -0.5 -1.3 1.6 -2.0 -3.4 -2.0 -0.9
Body Mass Index (BMI) (2010) 7.9 10.8 73.5 -1.5 -0.8 8.6 1.8 -1.7 0.2 -2.0 -0.1
Coronary Artery Disease (CAD) 1.2 1.4 2.7 1.6 1.0 1.6 -1.6 1.0 -0.3 -0.2 1.3
Crohns Disease (2012) 1.0 1.6 4.9 -0.6 0.1 0.9 2.1 -1.4 0.2 -2.2 0.6
Mean Putamen Volume 0.3 0.3 1.5 0.0 0.0 0.8 0.4 0.1 0.0 -1.2 -0.4
Fasting Glucose 0.7 0.8 1.6 1.1 -0.0 0.5 -1.1 1.0 0.9 -0.2 1.3
HbA1C 0.4 0.5 2.0 0.3 -0.5 0.7 -1.4 0.3 -0.5 -0.6 0.1
HDL Cholesterol 0.3 0.5 2.1 0.1 -0.1 -1.5 -0.3 0.2 1.2 0.3 -0.1
LDL Cholesterol 0.4 0.7 1.4 -0.7 -0.8 1.2 -0.9 -0.7 -0.9 0.6 -0.3
Lupus 1.7 2.6 5.4 1.8 2.1 -0.7 -2.3 2.1 1.1 0.9 0.7
Neuroticism (2016) 0.2 0.3 1.1 -1.0 -0.0 0.8 0.1 -0.2 -0.0 0.7 -0.6
Primary Biliary Cirrhosis 0.3 0.4 1.2 0.2 0.3 -1.0 -0.3 0.2 0.7 1.1 -0.7
Rheumatoid Arthritis 0.8 1.1 3.5 -0.6 -0.5 0.8 0.7 -1.1 -1.5 -1.9 -0.1
Schizophrenia (2014) 1.0 2.2 10.2 -0.7 0.2 -1.3 0.3 -1.1 -3.2 -2.0 -0.6
Triglycerides 0.7 1.1 5.1 -0.2 -0.8 2.3 -0.6 -0.4 -1.2 -0.7 -0.6
Type 2 Diabetes (T2D) (2012) 3.0 3.5 9.2 2.2 1.2 3.0 -1.4 1.8 2.2 -0.3 1.4
Ulcerative Colitis 0.3 0.5 1.7 0.6 1.3 -0.9 -0.4 0.5 -0.3 -0.5 0.6
Blood Eosinophil Count 0.1 1.0 2.2 1.0 1.1 0.9 -1.5 1.1 0.4 0.4 1.2
Blood Platelet Count 0.4 4.3 12.3 2.3 3.5 -1.5 -2.5 2.0 1.0 0.6 1.6
Blood Red Count 0.2 2.1 4.0 2.0 1.1 0.3 -2.0 1.8 1.8 1.1 0.4
Blood White Count 0.5 3.4 4.9 1.9 0.2 2.2 -2.0 1.9 2.2 2.2 1.2
Heel T-Score 0.3 2.5 5.1 1.9 0.7 0.2 -2.3 1.6 2.2 1.8 0.1
BMI 8.1 46.8 357.2 -1.0 -2.5 18.9 2.0 -1.2 1.0 -1.7 1.0
Height 3.6 70.1 207.4 -9.4 -7.1 3.1 14.4 -10.0 -6.4 -7.7 -2.5
Waist Hip Ratio (WHR) 2.8 12.6 38.5 3.8 1.7 -1.0 -6.2 4.0 2.1 4.8 1.0
Systolic Blood Pressure 0.2 1.1 2.7 -0.4 -1.6 -0.3 -1.6 -0.3 -0.7 0.4 -1.6
Smoking Status 0.5 1.1 3.4 0.9 0.2 1.8 -1.4 0.6 0.3 1.6 -0.0
Allergy or Eczema 0.5 1.3 3.1 -1.3 -1.4 1.2 -0.3 -1.0 -0.8 0.7 -1.8
Cardiovascular Disease 1.4 4.5 14.1 1.8 1.0 3.3 -3.8 2.0 -0.1 1.2 1.1
Hypothyroidism (self reported) 0.1 0.3 1.2 -0.3 -0.7 1.1 -0.1 -0.6 -0.4 0.1 0.6
Respiratory disease 0.6 1.4 4.8 0.3 -1.1 2.2 -1.2 0.2 -1.0 -1.5 0.8
Type 2 Diabetes (T2D) (2018) 10.0 18.8 29.0 5.4 3.8 4.4 -5.0 5.3 3.5 2.1 4.3
Lung FEV1/FVC ratio 0.4 2.3 6.1 -1.9 -2.5 0.7 1.0 -1.2 -0.9 -0.1 -2.2
Lung FVC 0.6 3.3 7.5 1.6 0.7 -2.5 -1.9 1.8 2.7 1.6 -0.3
Neuroticism 0.1 0.2 1.1 0.1 0.2 0.1 0.5 0.1 0.7 0.1 1.1
Chronotype (morning person) 2.0 4.6 26.4 -1.3 -2.4 5.1 0.5 -0.4 0.8 -0.1 -1.6
Hair Pigment 0.0 0.1 0.3 -0.1 0.0 -0.5 0.4 -0.0 -0.3 -0.3 -0.5
Tanning 0.0 0.1 0.2 0.0 -0.2 0.3 -0.4 -0.5 -0.5 -0.5 0.1
Hand grip strength (left) 0.7 1.9 5.1 -1.8 -0.5 -0.7 2.2 -1.5 1.3 0.3 -1.4
Number of treatments/medications taken 0.5 0.9 3.6 0.7 0.2 1.9 -1.6 0.3 -0.6 0.4 0.3
Average weekly spirits intake 2.5 3.1 13.4 -1.8 -0.1 3.7 0.8 -1.5 -1.0 -0.1 -2.1
Sensitivity / hurt feelings 0.3 0.6 1.6 0.7 0.3 0.7 -1.3 0.4 1.1 0.5 0.7
Frequency of depressed mood in last 2 weeks 0.3 0.5 3.2 0.1 0.2 1.8 -0.0 0.5 0.5 0.2 0.1
Hearing difficulty/problems: Yes 3.6 5.5 11.8 -2.8 -2.5 -0.7 3.4 -2.8 -2.3 -1.7 -1.2
Relative age of first facial hair 0.8 1.6 6.7 -0.4 -0.7 -2.6 0.5 -0.3 -0.5 1.6 -1.5
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 0.6 0.7 -0.6 -0.3 -0.3 -0.1 -0.4 -0.4 0.0
Ever used hormone-replacement therapy (HRT) 0.6 0.8 3.0 0.0 0.5 0.6 -1.4 0.3 -0.3 1.7 -0.6
Ever had hysterectomy (womb removed) 1.8 2.1 4.5 1.8 2.1 -1.9 -1.5 1.2 -0.4 -0.5 1.2
Systolic blood pressure, automated reading 0.5 1.3 3.1 -0.9 -1.5 1.8 -0.3 -0.9 -0.7 0.7 -1.6
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 4.9 0.0 -0.7 2.2 -0.6 0.1 -0.5 0.8 -0.4
Angina 0.6 0.8 2.8 0.7 0.2 -0.7 -1.7 0.7 0.1 1.5 -0.1
Medication for hormone replacement therapy 0.6 0.7 4.4 -0.0 0.4 -2.1 -0.4 0.4 -0.7 -0.1 -0.5
Vitamin and mineral supplements 0.5 0.6 1.5 0.5 0.6 -1.2 -1.1 0.4 0.4 1.2 0.0
Supplements: Zinc 0.5 0.6 1.1 0.0 -1.1 1.1 0.5 -0.4 -0.5 -0.8 0.9
Medication: Co-codamol 0.7 0.8 2.0 0.6 0.8 0.8 -1.4 0.7 -0.0 1.1 -0.9
Medication: Metformin 7.5 10.5 17.0 4.1 3.3 3.2 -3.4 3.8 2.3 1.2 3.6
Diabetes (father) 1.0 1.2 8.3 -0.1 -0.1 2.9 0.8 -0.6 -0.3 -0.2 0.4
Diabetes (mother) 3.9 4.9 10.3 3.2 1.7 0.9 -3.2 3.0 1.3 1.1 1.9
Severe depression (siblings) 1.4 1.5 3.7 -1.5 -1.1 -0.3 0.6 -1.2 -1.8 0.3 -1.9
Pack years adult smoking proportion 0.8 1.2 2.6 0.8 0.7 -1.6 -0.4 0.8 -1.1 -1.3 1.5
Impedance of leg (right) 8.2 39.7 182.2 4.6 3.9 -13.5 -6.6 4.9 2.2 5.0 1.1
Leg fat-free mass (left) 9.0 47.9 182.2 -5.4 -5.0 13.5 8.6 -5.7 -2.9 -5.6 -0.8
Trunk fat percentage 2.8 11.3 83.2 -0.1 -1.5 9.1 0.4 -0.3 -0.6 -1.6 1.3
Hand grip strength (right) 1.7 4.5 13.9 -2.6 -1.9 -1.4 3.7 -2.4 0.7 -0.5 -1.7
Townsend deprivation index at recruitment 0.7 1.0 4.8 0.1 0.3 -1.2 -1.1 0.0 -2.2 -0.8 0.3
Current tobacco smoking 0.5 0.8 2.1 1.2 1.0 -0.1 -1.4 0.8 -0.5 1.0 0.4
Average weekly fortified wine intake 1.0 1.1 2.5 -1.6 -1.6 1.3 0.7 -0.9 -0.6 -0.0 -0.7
Maternal smoking around birth 1.5 2.2 10.8 0.6 0.3 -3.3 -1.8 0.8 -0.9 1.3 -0.3
Fed-up feelings 0.3 0.6 2.7 0.1 0.4 1.7 -1.2 0.4 -0.2 0.0 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 1.2 0.7 1.1 0.9 -0.9 1.1 0.4 0.7 0.8
Relative age voice broke 0.8 1.3 3.5 -0.5 -1.0 -1.9 -0.2 -0.4 -0.7 1.4 -1.7
Taking other prescription medications 1.1 1.7 7.5 0.8 0.2 1.9 -2.7 0.4 -1.3 0.2 0.1
Age when periods started (menarche) 2.2 5.3 34.7 0.6 1.2 -5.9 -1.0 0.7 0.2 2.0 -0.2
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 2.7 1.4 1.6 0.0 -0.6 1.1 0.3 -0.0 1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.4 1.2 0.8 1.1 -0.0 0.8 1.0 0.3 1.0
Tinnitus: Yes, but not now, but have in the past 2.1 2.2 4.2 -1.5 -1.8 -0.7 1.7 -1.8 -2.1 -0.7 -1.2
Qualifications: CSEs or equivalent 0.8 1.0 2.4 -1.3 0.5 0.8 0.4 -1.0 -1.6 -0.1 -1.4
Serious illness, injury or assault to yourself 0.2 0.2 1.0 0.4 -0.3 0.0 -0.2 -0.4 -0.4 -1.0 0.3
High blood pressure 1.8 5.0 15.8 2.3 0.8 2.6 -4.0 2.2 0.1 2.4 0.9
Hayfever, allergic rhinitis or eczema 0.2 0.5 1.7 -0.7 -1.3 0.4 -0.1 -0.7 -0.2 0.0 -1.1
Multivitamins +/- minerals 0.7 0.9 2.4 -0.5 0.1 1.3 1.3 -0.4 -0.7 -1.6 0.8
Stomach or abdominal pain in last month 0.4 0.5 1.3 -0.4 1.1 0.3 -0.0 -0.1 -1.1 -0.9 0.8
Supplements: Glucosamine 1.1 1.5 3.5 0.1 -1.1 0.8 1.7 -0.6 -0.4 -1.7 1.9
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.4 0.6 -0.4 -0.3 0.3 -0.3 -0.2 -0.0 0.4
Medication: Atenolol 1.7 2.2 4.3 -1.6 -1.4 1.4 1.1 -2.1 -2.0 -0.3 -1.2
Medication: Levothyroxine sodium 0.5 0.8 3.0 -0.1 0.0 1.7 -0.1 -0.6 -0.6 -1.5 0.5
Sitting height 3.7 26.1 83.4 -5.7 -4.4 2.1 9.1 -6.0 -2.7 -4.8 -1.9
Chronic bronchitis/emphysema (father) 4.3 5.1 11.2 -2.3 -2.0 1.7 1.2 -2.6 -3.3 -1.7 -2.5
High blood pressure (mother) 0.6 0.8 2.4 0.3 0.8 0.9 -1.3 0.7 -0.1 1.5 -0.7
Body mass index (BMI) 6.2 26.3 204.3 -0.5 -1.8 14.3 0.5 -0.7 -0.2 -1.3 0.6
Impedance of leg (left) 8.0 38.8 185.0 4.3 3.5 -13.6 -6.6 4.5 1.8 5.3 0.5
Leg predicted mass (left) 9.0 47.8 182.2 -5.4 -5.1 13.5 8.5 -5.7 -2.9 -5.6 -0.8
Trunk fat mass 4.6 19.9 134.6 -1.3 -2.4 11.6 2.3 -1.6 -1.2 -2.6 0.9
Waist circumference 6.1 22.4 163.8 -1.2 -2.4 12.8 1.4 -1.6 -1.3 -1.4 0.2
Number of incorrect matches in round 0.1 0.1 0.3 -0.3 0.5 -0.3 -0.3 -0.1 -0.1 0.6 -0.4
Past tobacco smoking 3.3 6.1 13.2 2.7 3.0 -3.6 -1.4 2.5 1.9 0.6 2.6
Alcohol usually taken with meals 1.6 2.5 7.6 -1.4 -0.9 2.0 2.8 -1.0 0.6 -2.1 -0.2
Nervous feelings 1.6 3.0 10.3 1.4 0.4 -3.2 -1.9 1.7 1.3 1.9 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 1.2 0.6 0.2 -0.7 -0.7 1.1 0.9 0.8 0.8
Hearing difficulty/problems with background noise 3.7 6.0 12.0 -3.2 -3.5 -0.5 3.3 -2.9 -1.5 -1.2 -1.7
Hair/balding pattern: Pattern 2 2.6 3.3 9.5 2.0 3.1 -1.8 -0.9 2.0 1.2 -0.4 1.8
Had menopause 0.6 0.8 2.3 1.1 0.8 -0.6 -1.5 0.8 0.1 0.9 0.2
Had other major operations 0.3 0.3 1.2 0.1 0.1 -0.5 0.4 -0.2 -0.3 -1.1 0.9
Forced vital capacity (FVC) 1.1 4.4 14.4 -2.2 -1.9 -1.3 3.8 -2.0 0.1 -2.1 -1.3
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 4.3 0.9 0.6 2.1 -0.0 0.7 0.6 0.1 1.0
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 2.0 -0.8 -1.3 0.3 1.4 -0.9 0.2 -0.5 0.3
Qualifications: None of the above 3.5 7.5 27.1 3.3 1.6 -2.0 -5.2 3.2 0.0 1.6 1.7
Financial difficulties in last 2 years 0.8 1.1 2.9 -0.4 1.2 1.7 -0.9 -0.3 -1.6 -0.6 -0.7
Mouth/teeth dental problems 0.4 0.6 1.7 -0.3 0.1 -1.0 1.1 -0.5 0.1 -1.3 0.5
Heart attack 0.2 0.3 1.1 -0.4 0.2 0.3 -0.4 -0.2 -0.1 0.7 -1.0
Allergy 0.3 0.7 2.4 0.6 0.7 -1.6 -0.4 0.7 0.2 1.3 -0.4
Pain all over the body in last month 1.2 1.3 3.7 -0.8 -1.3 -0.4 -1.2 -0.4 0.4 1.6 -1.9
Diabetes (self-reported) 8.2 12.6 21.3 4.6 3.3 3.6 -4.3 4.3 1.5 1.5 3.7
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.5 -0.6 -0.1 -1.2 -0.2 -0.1 -0.4 1.6 -1.2
Medication: Ramipril 0.5 0.7 4.1 -0.3 0.8 2.0 -0.0 -0.4 0.2 0.7 -0.1
Medication: Simvastatin 1.4 2.1 9.1 1.0 -0.3 3.0 -1.6 1.0 0.3 1.6 0.1
Fluid intelligence score 6.0 12.4 34.3 -4.0 -2.0 2.5 5.9 -4.0 -1.6 -4.5 -0.1
Illnesses of siblings 3.5 4.9 15.7 -1.6 -0.1 -1.9 3.8 -1.5 0.4 -4.0 0.8
Neuroticism score 0.1 0.2 0.5 0.1 -0.5 0.0 -0.5 0.1 0.5 0.7 -0.3
Weight 7.4 36.2 201.6 -3.4 -4.0 14.2 5.3 -3.8 -2.1 -3.8 -0.2
Impedance of arm (right) 2.9 13.5 104.0 0.9 0.8 -10.2 -0.9 0.8 -0.3 0.3 1.0
Arm fat percentage (right) 4.2 16.6 125.4 -0.3 -1.5 11.2 0.4 -0.5 -0.2 -1.8 1.2
Trunk fat-free mass 6.4 36.9 118.8 -5.2 -4.4 10.9 8.2 -5.6 -2.8 -4.5 -1.4
Hip circumference 8.5 36.6 174.2 -4.1 -4.0 13.2 6.1 -4.5 -2.9 -4.5 -0.4
Time employed in main current job 0.7 0.8 2.1 -1.4 -1.2 0.2 -0.1 -0.6 -0.1 0.3 -1.5
Alcohol intake versus 10 years previously 1.1 1.7 6.5 1.4 1.7 0.2 -2.5 1.3 -0.3 0.1 0.6
Father’s age at death 0.5 0.7 2.8 -0.7 -0.5 -0.4 1.7 -0.9 -0.2 -1.0 -0.5
Worrier / anxious feelings 0.8 1.6 4.3 0.6 -0.8 -0.8 -1.5 0.9 2.1 1.8 0.1
Frequency of tiredness / lethargy in last 2 weeks 1.1 1.8 4.3 1.6 0.8 0.4 -2.1 1.7 -0.3 -0.5 1.7
Falls in the last year 0.7 1.0 2.2 0.9 0.6 1.5 -1.0 0.8 1.3 -0.0 1.0
Hair/balding pattern: Pattern 3 0.8 1.2 3.2 1.8 1.4 -0.2 -1.2 1.1 0.7 0.1 1.1
Number of live births 1.9 2.7 7.5 -2.1 -0.6 -0.5 1.2 -2.2 -2.7 -1.4 -0.9
Forced expiratory volume in 1-second (FEV1) 0.8 2.8 7.3 -1.8 -2.1 -1.1 2.7 -1.4 0.6 -1.6 -1.2
Pulse rate 8.0 13.5 27.1 4.4 2.7 -2.1 -5.2 4.7 3.2 4.0 1.1
Happiness 0.7 0.8 3.4 0.2 0.1 0.5 0.8 0.1 1.8 0.6 1.3
Noisy workplace 0.9 1.1 5.4 0.6 0.3 0.2 -2.3 0.6 0.3 1.4 -0.6
Qualifications: A levels/AS levels or equivalent 2.3 5.2 16.1 -2.7 -3.0 0.9 4.0 -2.5 -0.2 -1.2 -1.0
Serious illness, injury or assault of a close relative in last 2 years 3.9 4.5 8.1 -2.8 -1.0 2.4 2.8 -2.6 -1.3 0.6 -2.2
Mouth/teeth dental problems: Dentures 0.7 1.1 2.0 1.1 1.0 1.4 -1.4 1.0 -0.7 0.3 1.2
Asthma 0.6 1.1 3.6 -0.3 -0.2 1.9 -0.0 -0.4 -0.9 -1.9 0.8
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 2.2 -0.8 0.5 -1.5 0.7 -0.4 -0.4 -1.2 -0.2
Medication: Cholesterol lowering 2.7 4.2 12.7 -1.7 -2.0 3.6 0.6 -2.2 -2.1 -1.2 -1.7
Depression (self-reported) 0.2 0.3 0.8 0.1 -0.3 0.6 -0.9 0.0 0.4 0.8 -0.0
Medication: Lansoprazole 1.8 2.1 7.0 2.0 1.1 -0.1 -2.7 1.5 0.4 0.0 1.5
Prospective memory result 1.7 2.1 4.1 2.0 0.4 -1.8 -2.0 1.9 0.0 0.8 1.0
Lung cancer (father) 1.3 1.5 2.9 -1.5 -1.6 -0.2 0.9 -1.4 -1.7 -0.1 -1.0
Illnesses of mother 1.4 1.8 6.3 -0.8 -0.4 -0.7 2.0 -1.1 -0.8 -2.5 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.7 7.1 -1.5 -1.8 -0.9 2.7 -1.2 1.1 -2.2 -0.5
Pulse wave Arterial Stiffness index 1.1 1.3 3.6 1.6 1.1 0.4 -1.9 1.6 0.2 0.5 0.2
Impedance of arm (left) 2.8 12.7 98.0 0.8 0.8 -9.9 -0.5 1.0 -0.1 0.4 1.1
Arm fat mass (right) 6.1 25.0 169.0 -1.8 -2.7 13.0 2.5 -2.1 -1.2 -2.8 0.5
Trunk predicted mass 6.4 36.7 118.8 -5.2 -4.4 10.9 8.3 -5.6 -2.7 -4.4 -1.5
Standing height 3.8 37.5 116.6 -6.8 -5.5 1.3 10.8 -7.2 -4.3 -5.5 -2.0
Length of working week for main job 0.5 0.6 1.9 0.3 0.6 -0.3 -0.7 1.0 0.1 1.4 -0.9
Exposure to tobacco smoke at home 1.8 2.0 4.8 1.4 1.9 1.0 -2.2 1.6 0.6 1.2 0.6
Breastfed as a baby 1.2 1.5 3.1 -1.1 -1.8 0.1 1.7 -1.0 -1.2 -1.3 -0.5
Tense / ‘highly strung’ 0.3 0.4 1.4 0.1 0.3 -1.2 -0.8 0.5 -0.0 1.0 -0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 6.1 -1.2 -1.3 2.5 0.3 -1.1 -0.3 1.1 -0.6
Hair/balding pattern: Pattern 4 1.0 2.4 6.4 1.3 1.5 -0.3 -2.5 2.0 1.4 1.6 0.6
Birth weight of first child 1.8 3.2 10.6 -2.3 -0.7 -0.2 3.3 -2.1 -0.6 -2.0 -0.6
Peak expiratory flow (PEF) 0.7 1.6 5.0 -1.0 -1.4 0.3 2.2 -0.7 1.1 -1.7 -0.2
Pulse wave reflection index 0.6 0.8 3.0 -0.8 -0.0 0.7 0.8 -0.8 -0.8 -1.7 0.6
Ever highly irritable/argumentative for 2 days 3.9 4.7 9.6 -2.5 -3.1 2.2 2.0 -2.8 -2.0 -0.0 -1.0
Loud music exposure frequency 1.0 1.1 4.4 0.2 0.5 0.1 1.0 -0.3 0.2 -2.1 1.6
Qualifications: O levels/GCSEs or equivalent 2.8 4.4 9.6 -2.4 -2.2 1.8 3.1 -2.7 -0.7 -0.6 -1.9
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 1.8 -0.4 -0.7 0.7 1.2 -0.3 1.3 0.3 -0.6
Blood clot in the leg (DVT) 0.6 0.7 1.5 0.3 1.2 1.1 0.6 -0.1 0.6 -1.0 1.2
Medication: Paracetamol 0.7 1.2 2.7 0.4 1.6 -1.6 -0.8 1.0 -0.8 0.3 1.4
Headache pain in last month 2.0 3.5 5.8 2.0 1.7 -1.8 -2.4 2.2 1.2 1.8 1.7
Medication for cholesterol, blood pressure or diabetes 3.9 6.5 19.4 2.1 2.7 -4.4 -0.9 2.6 2.7 1.7 1.6
Glaucoma (self-reported) 0.8 0.9 2.3 0.4 -0.6 0.9 -1.4 0.3 1.0 1.5 -0.7
Gout (self-reported) 0.3 0.4 0.6 -0.8 -0.7 0.6 0.8 -0.5 0.4 -0.3 -0.7
Hypothyroidism/myxoedema (self-reported) 0.4 0.7 3.2 -0.3 -0.7 1.8 -0.2 -0.8 -0.8 -0.5 -0.4
Medication: Amlodipine 0.7 0.9 3.3 -0.7 -0.6 1.8 -0.1 -0.9 -1.4 -0.1 -0.8
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.3 -0.7 -1.1 0.5 -0.3 -0.4 -1.1 -0.1 -0.1
Birth weight 2.8 6.0 10.2 -2.8 -2.3 2.7 3.2 -3.0 -1.4 -0.6 -2.4
Chronic bronchitis/emphysema (mother) 0.9 1.0 2.2 0.8 1.1 -1.5 -1.4 1.0 0.3 0.8 0.4
High blood pressure (siblings) 1.5 2.2 7.8 1.0 0.2 1.6 -2.8 1.2 -0.8 2.0 -0.2
Forced vital capacity (FVC), Best measure 1.2 4.5 15.3 -2.0 -1.9 -1.1 3.9 -2.0 0.6 -2.7 -0.7
Body fat percentage 3.3 12.9 97.4 0.8 -0.9 9.9 -0.9 0.6 -0.0 -0.7 1.6
Leg fat percentage (right) 4.4 15.8 94.4 2.6 0.6 9.7 -3.6 2.4 1.2 1.5 1.5
Arm fat-free mass (right) 5.7 29.3 127.7 -4.0 -3.6 11.3 6.5 -4.2 -2.1 -3.5 -1.0
Exposure to tobacco smoke outside home 1.1 1.5 4.1 -0.1 -0.0 2.0 -1.4 0.1 -0.9 1.5 -1.6
Comparative body size at age 10 8.4 23.3 182.2 -0.3 -0.9 13.5 0.5 -0.3 0.3 -1.4 0.8
Number of full brothers 0.4 0.6 1.5 -0.2 0.6 0.2 -0.7 -0.3 -1.2 0.9 -1.1
Worry too long after embarrassment 0.9 1.5 3.0 -1.4 -1.2 0.7 1.7 -1.4 0.8 -0.6 -1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.2 0.4 0.0 -0.5 0.3 -0.6 0.3 -0.3 0.6 0.1
Wheeze or whistling in the chest in last year 1.3 2.3 6.5 -1.2 -2.2 2.6 -0.6 -1.2 -1.8 -0.0 -0.8
Number of children fathered 0.6 0.6 1.7 -0.6 -0.7 1.0 0.4 -0.6 -1.3 -1.0 0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 2.7 0.1 0.5 1.6 -1.0 0.7 -0.5 -0.4 0.9
Age at first live birth 1.4 2.5 6.5 -1.9 -1.9 1.2 2.6 -1.4 0.6 -0.8 -1.5
Pulse wave peak to peak time 2.1 2.4 6.7 -2.0 -1.6 -0.5 2.6 -2.1 -0.6 -0.9 -0.4
Health satisfaction 3.7 4.8 9.3 3.1 2.3 0.4 -2.8 2.4 1.9 0.8 2.5
Shortness of breath walking on level ground 0.4 0.4 1.3 -0.0 0.4 1.1 -0.4 -0.6 -0.3 -1.1 -0.5
Qualifications: College or University degree 2.5 7.8 33.2 -3.1 -2.0 1.4 5.8 -3.1 1.1 -1.2 -1.4
Eye problems/disorders: None of the above 1.0 1.2 2.6 -1.2 1.2 -1.1 1.6 -1.1 -0.1 0.7 -0.8
Mouth/teeth dental problems: Loose teeth 2.2 2.6 6.2 1.4 1.6 0.0 -1.9 1.7 1.8 2.5 1.0
Emphysema/chronic bronchitis 0.9 1.0 4.5 -0.0 -0.2 1.2 -0.5 -0.4 -2.1 -1.1 0.3
Medication for pain relief, constipation, heartburn 0.8 1.4 2.8 -0.7 -1.3 1.6 1.7 -1.0 1.1 0.0 -1.1
Neck or shoulder pain in last month 0.3 0.4 0.7 0.8 0.6 -0.9 -0.6 0.6 0.4 -0.2 0.7
Medication: Blood pressure 1.5 2.6 9.3 -1.2 -2.1 3.0 0.1 -1.6 -1.4 -0.5 -1.1
Angina (self-reported) 0.9 1.2 4.0 1.0 0.4 -0.9 -2.0 1.0 0.3 1.5 0.1
Migraine (self-reported) 1.6 2.0 4.2 1.3 1.3 -0.5 -1.9 1.4 1.5 2.1 -0.4
Medication: Ibuprofen 0.3 0.4 1.1 -0.2 1.1 -1.0 0.6 0.1 0.4 -0.6 -0.2
Medication: Allopurinol 1.8 2.4 5.2 -2.3 -0.9 1.5 2.0 -2.2 -0.4 -1.1 -0.9
Medication: Omeprazole 0.9 1.1 3.9 -0.3 0.1 -1.2 -1.7 -0.3 -2.0 -0.5 -0.1
Medication: Seretide 50 evohaler 1.3 1.5 4.2 1.4 1.1 -1.2 -1.1 1.0 0.2 -1.0 2.0
Mean time to correctly identify matches 0.4 0.7 1.7 -0.7 -1.3 -0.1 0.0 -0.3 0.5 1.3 -1.1
Heart disease (mother) 0.5 0.6 2.5 -0.2 -0.8 0.5 -0.3 -0.1 0.9 1.6 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 2.4 -0.4 0.1 0.8 0.7 -0.5 -1.6 -1.3 1.0
Whole body fat mass 5.0 20.9 151.3 -0.9 -2.1 12.3 1.8 -1.2 -0.7 -2.1 0.9
Leg fat mass (right) 5.3 20.7 161.3 -0.1 -1.8 12.7 0.3 -0.3 -0.0 -0.7 0.8
Arm predicted mass (right) 5.9 30.3 139.2 -3.9 -3.6 11.8 6.2 -4.2 -2.3 -3.4 -0.9
Pulse rate, automated reading 10.4 33.8 56.1 7.3 4.5 -2.3 -7.5 7.5 6.2 5.5 3.3
Alcohol intake frequency. 0.6 1.5 5.5 1.2 0.1 2.3 -1.7 0.8 0.8 0.5 -0.1
Comparative height size at age 10 3.7 20.6 52.1 -5.0 -4.2 3.6 7.2 -4.9 -4.0 -3.9 -1.2
Number of full sisters 0.5 0.7 1.4 -0.8 -0.6 0.9 -0.5 -0.5 -1.0 0.8 -1.2
Suffer from ‘nerves’ 0.4 0.7 2.0 -0.0 -1.0 -1.3 -0.5 0.2 -0.0 1.4 -0.8
Overall health rating 4.4 9.4 23.2 4.2 2.7 0.5 -4.8 3.7 1.3 2.1 2.6
Chest pain or discomfort 0.3 0.5 1.2 -0.6 -0.4 1.1 -0.4 -0.8 -0.7 0.8 -0.7
Had major operations 2.7 3.2 6.0 -1.6 -1.5 2.3 1.7 -1.9 -1.4 -2.4 -0.8
Age at last live birth 1.5 2.2 4.2 -2.0 -2.0 -0.3 1.9 -1.6 -0.9 -0.6 -1.4
Family relationship satisfaction 1.1 1.4 5.3 0.7 -0.0 -0.1 -1.0 0.9 1.8 2.3 0.3
Leg pain on walking 0.6 0.8 2.9 0.8 1.7 0.4 -1.0 0.6 0.7 1.0 -0.1
Qualifications: NVQ or HND or HNC or equivalent 2.7 3.3 8.0 1.7 2.8 -2.0 -1.8 1.6 0.6 1.2 2.0
Commuting to job workplace: Car/motor vehicle 0.1 0.2 0.4 0.0 -0.6 0.6 -0.0 0.2 0.2 0.4 -0.6
Illness, injury, bereavement, stress in last 2 years 1.0 1.3 4.3 1.2 0.5 -1.0 0.1 1.0 2.1 0.7 1.3
Medication: Aspirin 0.9 1.2 3.1 1.3 0.5 0.7 -1.7 1.4 1.0 0.5 0.9
Supplements: Vitamin C 0.6 0.8 4.1 0.5 0.5 -0.3 0.3 0.3 -0.4 -2.0 1.1
Knee pain experienced in last month 0.1 0.2 0.6 0.1 0.3 0.6 0.4 0.0 0.7 0.2 0.6
Hypertension (Self-reported) 1.9 5.2 18.0 2.2 1.0 2.5 -4.2 2.2 -0.2 2.5 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.5 4.8 1.4 1.3 0.1 -2.2 1.2 -0.3 0.2 1.5
Illnesses of father: Heart disease 0.2 0.2 1.0 -0.3 -0.6 0.1 0.1 -0.1 0.6 0.1 -1.0
Illnesses of siblings: Diabetes 1.9 2.3 6.4 -0.3 -2.5 2.5 -1.2 -0.3 -1.5 1.1 -1.1
Smoking status: Previous 2.6 3.9 11.8 -2.0 -2.1 3.4 0.4 -1.8 -1.1 0.2 -2.5
Forced expiratory volume in 1-second (FEV1), predicted 1.3 2.6 9.6 -1.8 -0.9 1.1 3.1 -1.8 -0.2 -1.6 -0.5
Whole body fat-free mass 7.6 43.4 156.2 -5.4 -4.8 12.5 8.5 -5.8 -2.9 -4.9 -1.2
Leg fat-free mass (right) 9.4 50.3 176.9 -5.8 -5.3 13.3 9.0 -6.2 -3.2 -5.7 -1.1
Arm fat percentage (left) 4.4 17.5 132.2 -0.2 -1.5 11.5 0.5 -0.4 -0.0 -1.8 1.3
Average weekly red wine intake 1.5 2.2 10.9 0.2 0.2 3.3 1.2 0.1 1.8 -1.1 1.1
Handedness (chirality/laterality): Left-handed 0.4 0.5 2.0 0.3 0.8 1.4 0.1 0.4 0.3 -0.4 0.7
Mood swings 0.3 0.5 1.5 0.3 1.2 0.1 -0.9 0.4 -0.4 0.9 0.9
Loneliness, isolation 0.7 1.0 2.3 1.4 1.3 0.2 -0.6 1.5 0.6 0.2 1.1
Long-standing illness, disability or infirmity 1.6 2.5 6.1 1.8 0.2 1.0 -2.5 1.5 1.6 1.8 1.1
Ever had bowel cancer screening 1.2 1.4 4.3 -0.7 -1.2 0.1 0.8 -1.3 -2.1 -1.6 -0.1
Diabetes diagnosed by doctor 9.0 14.7 24.1 4.9 3.8 4.2 -4.5 4.4 2.3 1.8 3.6
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.0 -0.5 -0.6 -0.7 -0.1 -0.7 -1.0 0.1 -0.5
Friendships satisfaction 0.8 1.0 1.7 -1.3 -1.0 0.5 1.3 -1.1 -0.1 1.0 -1.1
Qualifications: nursing, teaching 3.4 5.3 10.8 -2.6 -3.2 2.4 3.3 -2.3 -0.7 -1.1 -1.5
Commuting to job workplace: Walk 0.4 0.4 1.3 0.1 -0.1 0.8 0.8 -0.3 -0.6 -1.1 0.2
Eye problems/disorders: Cataract 0.6 0.7 3.0 0.4 -1.7 0.7 -1.2 0.7 0.2 -0.4 0.2
Mouth/teeth dental problems: Mouth ulcers 1.6 2.5 4.7 -2.2 -1.4 -0.7 1.0 -1.8 -2.1 -0.8 -2.0
Medication for cholesterol 3.1 4.7 16.3 -2.4 -1.4 -0.7 4.0 -2.5 -0.6 -2.5 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 0.5 0.5 0.4 0.7 -0.4 0.5 0.4 0.1 0.7
Back pain experienced in last month 2.8 4.0 12.5 2.1 3.5 0.2 -1.1 1.3 1.3 -1.0 3.1
Mineral and other dietary supplements 1.2 1.6 5.2 0.3 1.1 0.6 -1.6 0.9 0.9 2.3 -1.4
Breast cancer (self-reported) 1.6 1.9 4.3 -1.8 -0.9 -0.1 1.9 -2.1 -0.9 -0.3 -1.6
Asthma (self-reported) 0.5 1.1 3.8 -0.2 -0.4 1.9 -0.2 -0.3 -0.8 -1.8 0.8
Osteoporosis (self-reported) 2.2 2.8 6.1 1.8 1.6 -2.5 -1.4 1.6 0.9 0.9 1.9
Osteoarthritis (self-reported) 2.1 2.8 7.5 1.7 0.6 1.9 -2.7 1.9 0.9 1.8 -0.0
Medication: Aspirin 1.2 1.5 3.5 1.4 0.6 1.1 -1.9 1.4 1.2 1.1 0.9
Medication: Gliclazide 1.3 1.5 5.2 1.6 -0.2 2.3 -1.3 0.8 0.7 0.7 0.9
Illnesses of father: None of the above (group 1) 2.0 2.5 6.9 1.5 0.1 -2.6 -1.0 1.8 1.8 1.8 0.4
Smoking status: Current 0.2 0.3 0.6 0.7 0.6 0.2 -0.8 0.4 -0.5 0.7 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 13.6 1.0 1.2 -1.3 -0.9 1.1 3.7 1.0 0.2
Whole body water mass 7.7 44.0 156.2 -5.4 -4.8 12.5 8.6 -5.9 -3.0 -5.0 -1.3
Leg predicted mass (right) 9.3 49.6 176.9 -5.8 -5.2 13.3 8.9 -6.1 -3.1 -5.7 -1.1
Arm fat mass (left) 6.4 26.4 179.6 -1.8 -2.7 13.4 2.8 -2.1 -1.1 -2.8 0.6
Number of self-reported non-cancer illnesses 1.1 1.9 8.0 1.1 0.1 1.9 -2.8 0.7 -1.2 0.6 0.2
Average weekly champagne plus white wine intake 2.4 3.4 12.6 -2.0 -1.5 1.2 3.6 -2.2 -0.3 -0.6 -1.1
Miserableness 0.7 1.2 2.2 -1.5 -1.0 0.9 1.5 -1.4 -0.8 -0.6 -0.7
Guilty feelings 0.2 0.3 0.9 0.6 -0.1 0.6 -0.8 0.0 0.9 0.5 0.2
Wears glasses or contact lenses 2.0 2.3 7.8 1.6 0.0 -0.2 -1.5 1.8 1.4 2.8 0.2
Ever taken oral contraceptive pill 1.8 2.0 3.9 -1.7 -1.9 0.5 1.0 -1.8 -0.8 -0.9 -2.0
Hearing aid user 1.1 1.3 4.7 -0.6 -1.5 -2.2 0.8 -0.4 -1.3 -0.5 -0.5
Mother’s age at death 0.8 1.0 1.7 -1.2 -0.9 0.1 1.1 -1.3 -0.6 -1.0 -1.1
Financial situation satisfaction 1.1 1.4 2.9 1.4 1.7 -0.0 -1.3 1.2 -0.3 1.4 0.9
Tinnitus: Yes, now most or all of the time 1.1 1.3 3.0 0.6 0.8 -1.7 -1.0 1.2 1.7 0.9 0.0
Commuting to job workplace: Public transport 0.3 0.4 1.7 0.1 0.3 1.3 -0.2 0.4 0.2 0.9 0.1
Eye problems/disorders: Glaucoma 0.5 0.6 1.5 0.6 -0.4 0.9 -0.8 0.4 1.2 0.8 0.5
Medication: Blood pressure 1.9 3.6 8.3 2.1 0.9 2.3 -2.9 2.1 1.1 2.1 0.5
Pain type(s) experienced in last month: Hip pain 2.3 3.0 5.6 1.7 2.4 2.2 -1.5 1.4 1.2 0.6 2.0
Supplements: Fish oil (including cod liver oil) 0.6 0.8 2.3 -0.7 -1.5 -0.3 0.9 -0.9 -1.0 -1.1 0.3
High cholesterol (Self-reported) 0.7 1.2 5.8 0.1 0.7 2.4 -1.2 0.2 -0.9 1.1 -0.6
Medication: Bendroflumethiazide 1.0 1.5 8.4 -0.4 -1.2 2.9 -0.7 -0.4 -0.6 0.4 -0.9
Medication: Paracetamol 0.7 1.1 4.2 0.4 2.0 -0.7 -0.3 1.1 -0.2 -0.3 1.6
Medication: Lisinopril 0.7 0.9 2.2 0.2 -0.8 1.5 -1.0 0.6 0.8 1.5 -0.6
Medication: Atorvastatin 1.2 1.5 4.6 -1.1 -0.0 2.1 -0.7 -0.9 -0.3 0.8 -2.1
Illnesses of father: High blood pressure 1.1 1.3 4.9 -0.5 -0.1 1.9 -0.4 -0.5 -2.2 -1.2 0.6
Alcohol drinker status: Never 0.5 0.6 3.3 0.4 0.1 1.8 -0.1 -0.3 0.6 0.5 -0.6
Ever smoked 1.0 1.8 4.9 -1.2 -2.2 1.8 1.3 -1.2 -0.8 -1.0 -0.8
Basal metabolic rate 7.9 43.7 174.2 -5.1 -4.8 13.2 8.0 -5.5 -2.9 -4.9 -1.0
Leg fat percentage (left) 4.4 16.0 99.0 2.4 0.4 9.9 -3.6 2.2 1.0 1.7 1.2
Arm fat-free mass (left) 6.3 31.9 141.6 -4.1 -3.7 11.9 6.4 -4.5 -2.5 -3.8 -1.0
Number of operations (self-reported) 1.4 2.0 4.5 -1.0 -0.1 1.3 1.7 -1.7 -1.8 -2.1 -0.2
Average weekly beer plus cider intake 1.3 1.8 8.6 0.0 -0.6 -2.9 -1.3 0.1 -2.0 0.2 -0.1
Irritability 1.8 3.1 6.1 -2.0 -2.5 1.8 2.1 -2.1 -0.8 -0.3 -1.2
Risk taking 0.8 1.2 4.4 -1.0 -0.2 -1.2 0.5 -0.9 -2.1 -1.0 -1.0
Ever had prostate specific antigen (PSA) test 1.4 1.6 6.0 -0.9 0.3 0.7 2.4 -1.0 -0.8 -1.8 0.7
Fractured/broken bones in last 5 years 1.0 1.3 3.6 -0.8 -1.9 0.4 0.9 -0.8 -1.9 -1.0 -0.3
Age started oral contraceptive pill 0.1 0.1 0.4 0.2 0.6 0.0 0.2 0.3 0.0 -0.0 -0.5
Diastolic blood pressure, automated reading 0.3 0.8 2.8 -0.2 -0.6 0.1 -1.4 -0.0 -0.6 1.7 -0.9
Ever depressed for a whole week 1.1 1.3 2.9 -1.2 -0.5 1.6 1.6 -1.7 -0.5 -0.2 -0.6
Unable to work because of sickness or disability 0.8 1.0 2.8 1.0 1.7 -0.6 -1.2 1.2 0.6 0.5 0.7
Commuting to job workplace: Cycle 3.0 3.7 8.0 -2.5 -2.3 0.7 2.8 -2.5 -1.2 -1.2 -0.5
Myopia 1.1 1.5 5.2 -1.0 -1.0 -0.1 2.3 -1.7 0.3 -1.6 0.1
Vascular/heart problems diagnosed by doctor 1.6 4.3 14.9 -2.2 -1.0 -2.2 3.9 -2.1 0.2 -1.7 -1.0
Cholesterol lowering medication 2.9 4.2 9.2 2.1 1.9 1.4 -2.9 2.3 1.0 3.0 0.1
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 2.9 -0.2 0.3 -1.0 -1.2 -0.5 -1.7 -1.3 0.1
Pain experienced in last month 1.7 2.9 5.6 -1.9 -2.4 1.0 2.3 -1.6 -1.3 -0.7 -1.8
Supplements: Calcium 0.1 0.2 0.7 0.2 -0.2 -0.5 -0.0 -0.0 -0.8 -0.4 0.3
Basal cell carcinoma (self-reported) 1.0 1.2 4.1 -0.5 -0.1 0.2 2.0 -1.1 0.2 -1.8 0.7
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.5 -0.5 -0.1 0.5 -0.2 -0.4 -0.2 0.8 -1.2
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 2.0 0.6 1.4 0.8 0.4 0.1 0.6 -0.8 1.3
Heart disease (siblings) 3.6 4.4 13.4 2.3 1.7 0.6 -2.2 1.9 2.2 3.7 0.7
Alcohol drinker status: Previous 0.5 0.6 2.3 0.2 -1.3 -1.5 -0.1 -0.5 -0.8 -0.2 0.2
Pack years of smoking 1.0 1.4 2.8 0.8 0.6 -1.6 -0.5 0.8 -1.4 -1.5 1.7
Impedance of whole body 5.6 28.4 179.6 2.8 2.4 -13.4 -3.9 3.0 0.9 2.8 0.9
Leg fat mass (left) 5.3 20.8 161.3 -0.2 -1.9 12.7 0.3 -0.4 -0.2 -0.6 0.5
Arm predicted mass (left) 6.5 32.9 144.0 -4.2 -4.1 12.0 6.4 -4.7 -2.5 -3.6 -1.4