Best TWAS P=4.59e-10 · Best GWAS P=1.4e-11 conditioned to 0.000471
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | GGA3 | 0.22 | 0.00 | lasso | 4 | 0.00 | 0.3020 | -6.4 | -6.2 | 4.6e-10 | 0.67 | 0.04 | 0.36 | TRUE |
| 2 | GTEx | Brain Frontal Cortex BA9 | MRPL38 | 0.22 | 0.01 | enet | 20 | 0.02 | 0.0806 | -4.3 | -5.2 | 1.5e-07 | 0.54 | 0.04 | 0.48 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRB2 | 0.02 | 0.00 | blup | 43 | 0.01 | 0.0046 | -5.5 | -6.1 | 8.9e-10 | 0.89 | 0.01 | 0.82 | FALSE |