TWAS hub - GGA3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0800	0.0330	7.7e-04	0.030	NA	0.017	NA	0.029	1.5e-03	NA	1.3e-02	NA	2.0e-03
2	GTEx	Brain Cerebellar Hemisphere	0.2240	0.1080	6.5e-03	-0.005	NA	-0.003	NA	0.001	4.5e-01	NA	4.0e-01	NA	3.0e-01
3	GTEx	Breast Mammary Tissue	0.1460	0.0610	2.2e-03	0.080	NA	0.072	NA	0.081	6.5e-05	NA	1.5e-04	NA	5.9e-05
4	GTEx	Breast Mammary Tissue (Female)	0.0780	0.0773	1.9e-01	-0.005	NA	0.005	NA	-0.010	5.0e-01	NA	2.3e-01	NA	8.4e-01
5	GTEx	Colon Transverse	0.2690	0.0940	3.3e-04	0.081	NA	0.078	NA	0.081	1.1e-04	NA	1.5e-04	NA	1.1e-04
6	GTEx	Lung	0.1505	0.0446	1.3e-06	0.146	NA	0.093	NA	0.125	2.8e-11	NA	1.4e-07	NA	8.2e-10
7	GTEx	Stomach	0.1530	0.0570	9.4e-04	0.034	NA	0.052	NA	0.066	9.6e-03	NA	1.7e-03	NA	4.6e-04
8	GTEx	Thyroid	0.1110	0.0410	1.5e-04	0.090	NA	0.077	NA	0.085	2.1e-07	NA	1.6e-06	NA	4.8e-07
9	METSIM	Adipose	0.0630	0.0185	2.1e-07	0.029	0.056	0.045	0.055	0.044	2.6e-05	8.8e-09	2.3e-07	1.2e-08	2.9e-07
10	YFS	Blood	0.0437	0.0181	1.5e-03	0.006	0.008	0.015	0.012	0.010	3.8e-03	7.3e-04	9.0e-06	7.3e-05	2.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Lung FVC	5.0	25.2	46.5	5.2	6.8	4.0	4.8	5.3	4.7	5.5	4.9	5.9	0.5
Waist Hip Ratio (WHR)	4.9	21.8	36.5	-5.1	-6.0	-4.7	-4.7	-3.8	-4.8	-4.2	-4.8	-6.0	0.2
Illness, injury, bereavement, stress in last 2 years	4.3	5.2	8.4	2.5	1.3	2.4	2.3	2.2	2.2	1.4	2.5	2.6	2.9
Serious illness, injury or assault to yourself	3.9	4.7	9.3	-2.2	-3.0	-1.9	-2.0	-1.3	-2.1	-1.2	-2.1	-2.7	-2.5
Coronary Artery Disease (CAD)	3.8	4.6	8.0	1.6	2.3	2.6	1.8	2.1	1.6	2.8	1.6	1.6	2.8
Ever had hysterectomy (womb removed)	3.8	4.3	6.6	2.5	1.7	2.2	2.5	1.7	2.5	2.1	2.6	1.4	0.6
Asthma	3.8	7.5	12.1	-3.4	-1.9	-2.1	-3.5	-2.5	-3.5	-1.7	-3.4	-3.0	-1.0
Breast Cancer	3.6	8.7	14.0	3.1	2.4	2.6	3.0	3.7	3.1	3.1	3.0	3.7	-0.4
Asthma (self-reported)	3.4	6.8	11.2	-3.3	-1.6	-2.2	-3.3	-2.5	-3.3	-1.6	-3.3	-2.7	-1.0
Commuting to job workplace: Car/motor vehicle	3.3	3.8	7.7	-2.4	-0.9	-2.8	-2.4	-2.0	-2.4	-0.8	-2.4	-1.3	-0.6
Hair/balding pattern: Pattern 2	3.2	4.1	7.1	-2.0	-0.1	-2.4	-2.3	-2.7	-2.1	-1.8	-2.2	-1.3	-2.1
Triglycerides	3.0	5.0	7.2	-2.5	-0.4	-2.7	-2.6	-2.2	-2.6	-2.2	-2.6	-1.9	-1.5
High blood pressure	3.0	8.3	13.8	-3.3	-1.9	-2.8	-3.1	-3.0	-3.1	-3.7	-3.2	-2.7	-1.6
Hypertension (Self-reported)	2.9	8.0	12.9	-3.2	-2.0	-2.8	-3.0	-2.8	-3.0	-3.6	-3.0	-2.7	-1.8
Neck or shoulder pain in last month	2.7	3.8	6.8	-2.6	-0.6	-1.4	-2.5	-2.2	-2.5	-0.4	-2.5	-1.2	-1.9
Number of treatments/medications taken	2.6	4.7	7.6	-2.6	-1.4	-1.8	-2.4	-2.8	-2.5	-2.0	-2.4	-2.0	-1.3
Age when periods started (menarche)	2.6	6.2	9.6	2.6	3.0	2.9	2.6	2.1	2.5	3.1	2.6	1.9	0.0
Waist circumference	2.6	9.6	14.5	-3.7	-2.8	-2.1	-3.7	-2.9	-3.8	-2.2	-3.7	-3.2	-2.0
Pain all over the body in last month	2.6	2.7	6.0	1.4	1.7	2.3	1.6	1.9	1.5	2.4	1.6	0.7	0.1
Body Mass Index (BMI) (2010)	2.5	3.4	7.5	-1.9	-1.1	-2.7	-2.0	-1.4	-1.9	-2.1	-2.1	-1.7	-0.8
Leg pain on walking	2.5	3.1	6.3	-2.2	-1.1	-1.6	-2.0	-1.4	-2.2	-0.3	-2.0	-2.5	-0.8
Long-standing illness, disability or infirmity	2.5	3.8	8.3	-2.4	-1.6	-1.1	-2.0	-2.0	-2.3	0.5	-2.1	-2.9	-1.4
Pain type(s) experienced in last month: Hip pain	2.5	3.1	5.2	-2.3	-1.1	-1.8	-2.1	-2.2	-2.2	-0.1	-2.1	-1.7	0.3
Comparative height size at age 10	2.4	13.3	38.8	-3.9	-6.2	-2.0	-3.3	-3.2	-3.4	-2.3	-3.6	-4.8	0.8
Age at last live birth	2.4	3.5	6.6	-1.9	0.3	-2.5	-1.9	-0.6	-1.9	-2.6	-2.0	-1.9	1.9
Number of self-reported non-cancer illnesses	2.4	4.2	6.5	-2.5	-1.2	-1.8	-2.4	-2.5	-2.5	-0.7	-2.4	-2.2	-0.5
Vascular/heart problems diagnosed by doctor	2.4	6.6	10.0	2.8	1.7	2.4	2.7	2.5	2.7	3.2	2.8	2.2	2.4
Shortness of breath walking on level ground	2.3	2.7	5.3	-2.0	-1.6	-1.8	-1.8	-1.0	-1.8	-0.8	-1.9	-2.3	0.4
Mother’s age at death	2.3	2.8	10.7	1.7	1.0	0.7	1.7	3.3	1.6	0.6	1.6	0.8	2.1
Mouth/teeth dental problems: Bleeding gums	2.2	2.9	11.4	1.3	1.9	1.1	1.2	0.7	1.3	1.6	1.3	1.8	-3.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.7	10.9	1.7	3.3	2.1	1.3	1.8	1.2	3.1	1.4	2.9	1.6
Townsend deprivation index at recruitment	2.1	3.0	4.9	2.1	0.2	1.7	2.1	1.0	2.0	1.9	2.2	1.8	1.2
Trunk fat mass	2.1	8.9	14.3	-3.6	-2.5	-1.9	-3.7	-3.1	-3.8	-2.4	-3.7	-2.9	-1.2
Pulse wave Arterial Stiffness index	2.1	2.5	4.3	-1.9	-1.6	-1.2	-1.6	-1.7	-1.6	-1.0	-1.8	-2.1	0.8
Eye problems/disorders: Cataract	2.1	2.5	4.0	-1.9	-0.8	-2.0	-1.8	-1.3	-1.8	-1.3	-1.9	-1.4	-1.0
High cholesterol (Self-reported)	2.1	3.7	6.3	-2.1	-2.1	-1.3	-1.9	-1.8	-2.0	-2.5	-1.8	-2.0	1.5
Medication: Atorvastatin	2.1	2.6	6.0	-1.8	-1.6	-0.7	-1.8	-1.6	-1.7	-0.3	-1.7	-1.5	-2.5
Age started oral contraceptive pill	2.1	2.6	3.8	1.8	1.4	1.2	1.9	1.6	1.8	1.2	1.9	1.4	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.4	15.0	2.2	2.9	2.8	2.0	2.4	2.0	3.9	1.9	3.0	0.8
Birth weight	2.0	4.4	7.3	-2.2	-1.1	-2.7	-2.3	-2.0	-2.3	-2.3	-2.4	-2.1	-0.4
Supplements: Fish oil (including cod liver oil)	2.0	2.6	4.5	2.0	1.0	2.1	1.9	1.4	1.8	0.9	2.0	1.3	0.9
Ever had prostate specific antigen (PSA) test	2.0	2.3	6.2	1.6	2.5	1.5	1.1	2.1	1.0	0.6	1.3	1.8	-0.2
Cardiovascular Disease	1.9	6.3	10.6	-3.1	-1.5	-2.7	-2.8	-2.4	-2.9	-3.2	-2.9	-2.0	-0.1
Pulse wave peak to peak time	1.9	2.2	3.6	1.8	1.3	1.3	1.6	1.5	1.6	1.1	1.8	1.9	-0.7
HbA1C	1.8	2.0	5.0	1.2	-0.1	0.7	1.6	1.3	1.6	2.2	1.5	-0.0	2.0
Whole body fat mass	1.8	7.6	12.9	-3.3	-2.1	-1.7	-3.5	-2.8	-3.6	-2.1	-3.5	-2.5	-1.4
Hand grip strength (left)	1.7	4.4	7.3	-2.7	-1.0	-2.4	-2.6	-1.1	-2.6	-2.1	-2.6	-1.9	-0.4
Trunk fat percentage	1.7	7.0	11.7	-3.1	-1.6	-1.8	-3.4	-2.8	-3.4	-2.3	-3.3	-2.4	-1.0
Mouth/teeth dental problems	1.7	2.6	6.6	-1.0	-2.6	-1.3	-0.7	-1.2	-0.8	-1.2	-0.7	-2.5	2.4
Leg fat mass (right)	1.7	6.5	10.9	-3.0	-1.9	-1.4	-3.2	-2.6	-3.3	-1.6	-3.1	-2.2	-2.2
Overall health rating	1.7	3.7	6.7	-2.6	-0.1	-1.1	-2.5	-2.5	-2.5	0.2	-2.6	-1.7	-0.7
Forced vital capacity (FVC), Best measure	1.6	5.8	11.6	2.1	2.9	2.6	2.0	2.3	2.0	3.4	1.9	2.8	1.2
Number of children fathered	1.6	1.8	4.3	-1.1	-2.1	-1.2	-1.0	-1.5	-1.0	-1.6	-1.1	-1.8	-0.6
Medication: Allopurinol	1.6	2.2	5.2	-1.5	-2.3	-1.0	-1.4	-2.1	-1.3	-1.3	-1.5	-1.0	-0.4
Medication: Bendroflumethiazide	1.6	2.5	4.0	-1.6	-1.7	-1.7	-1.5	-1.3	-1.5	-2.0	-1.6	-1.8	-0.3
Bipolar Disorder (2018)	1.5	2.4	4.0	-1.5	0.4	-1.3	-2.0	-1.5	-1.9	-1.9	-1.9	-1.4	-0.9
Major Depression (MDD)	1.5	1.8	3.7	-1.2	-1.2	-1.5	-1.4	-1.9	-1.4	-1.6	-1.4	-0.7	-0.4
Average weekly fortified wine intake	1.5	1.8	3.4	-1.7	0.0	-1.8	-1.5	-0.8	-1.6	-1.4	-1.5	-1.3	0.3
Supplements: Glucosamine	1.5	2.0	4.0	1.3	-1.3	1.9	1.3	0.9	1.2	1.6	1.3	0.1	2.0
Had menopause	1.5	1.8	4.5	1.7	-0.2	1.4	1.7	-0.0	1.6	0.5	1.7	0.7	2.1
Forced expiratory volume in 1-second (FEV1)	1.5	4.9	13.1	1.6	2.8	2.2	1.6	2.2	1.5	3.6	1.5	2.4	1.8
Happiness	1.5	1.8	9.1	0.4	3.0	0.9	0.1	0.4	0.2	1.9	0.2	1.5	-1.4
Medication: Omeprazole	1.5	1.7	3.4	-1.4	-1.5	-1.0	-1.4	-1.9	-1.3	-0.2	-1.4	-1.4	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	8.1	0.1	0.3	1.7	0.2	-0.4	0.1	2.6	0.1	0.3	-2.8
Medication: Aspirin	1.5	2.0	3.2	-1.7	-0.1	-1.6	-1.6	-1.8	-1.6	-1.3	-1.6	-0.8	-0.7
Pain experienced in last month	1.5	2.5	4.0	1.7	2.0	1.3	1.6	1.9	1.8	-0.1	1.5	1.5	1.7
Lupus	1.4	2.2	8.7	-1.6	-2.9	-0.7	-1.3	-0.4	-1.3	-0.3	-1.4	-2.0	0.7
Length of working week for main job	1.4	1.6	4.9	1.3	1.1	0.8	1.2	2.2	1.2	0.6	1.2	1.7	0.1
Glaucoma (self-reported)	1.4	1.7	2.8	-1.6	-0.7	-1.3	-1.4	-1.2	-1.4	-1.7	-1.5	-1.2	0.3
Body fat percentage	1.4	5.4	9.5	-2.7	-1.3	-1.4	-3.0	-2.5	-3.1	-1.9	-2.9	-2.0	-1.3
Wheeze or whistling in the chest in last year	1.4	2.5	3.7	-1.9	-0.9	-1.4	-1.8	-1.4	-1.8	-0.3	-1.8	-1.9	-1.8
Medication: Gliclazide	1.4	1.6	3.9	-2.0	0.3	-0.5	-1.8	-0.9	-1.8	-0.1	-1.9	-0.9	-0.0
Leg fat mass (left)	1.4	5.7	10.1	-2.9	-1.5	-1.2	-3.1	-2.4	-3.2	-1.4	-3.0	-1.8	-2.3
Schizophrenia (2014)	1.3	2.8	5.2	-2.1	-1.1	-0.8	-2.2	-2.0	-2.3	-0.9	-2.2	-1.1	-1.0
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	2.9	1.7	1.4	1.2	1.6	1.4	1.6	1.6	1.7	1.6	0.4
Leg fat percentage (right)	1.3	4.7	7.5	-2.4	-1.3	-1.3	-2.7	-2.4	-2.7	-1.5	-2.5	-2.0	-2.2
Exposure to tobacco smoke outside home	1.3	1.7	8.1	0.9	2.9	1.0	0.6	0.3	0.6	1.3	0.7	1.6	-1.1
Health satisfaction	1.3	1.7	6.4	-1.3	1.0	0.7	-1.3	-1.0	-1.3	0.7	-1.4	-0.8	-2.5
Mineral and other dietary supplements	1.3	1.7	4.1	-1.5	-0.4	-1.8	-1.5	-0.8	-1.4	-0.4	-1.6	-0.6	-2.0
Smoking Status	1.2	2.9	4.4	1.6	2.1	1.4	1.6	1.7	1.6	1.5	1.7	1.9	-1.6
Allergy or Eczema	1.2	3.3	12.5	1.6	0.7	1.9	1.9	1.7	1.7	3.5	1.8	0.4	-0.7
Eye problems/disorders: None of the above	1.2	1.4	1.9	1.3	1.2	1.1	1.1	0.8	1.1	1.2	1.2	1.4	1.4
Mouth/teeth dental problems: Loose teeth	1.2	1.4	6.7	0.4	1.8	0.4	0.1	0.2	0.1	1.1	0.2	1.6	-2.6
Medication: Blood pressure	1.2	2.0	2.7	-1.7	-1.0	-1.2	-1.5	-1.5	-1.6	-1.6	-1.6	-1.6	-0.7
Family relationship satisfaction	1.2	1.4	7.3	-0.5	1.8	0.8	-0.7	-1.0	-0.7	0.7	-0.7	0.0	-2.7
Reaction Time	1.1	2.1	4.5	1.2	2.0	1.0	1.4	1.1	1.1	1.3	1.5	1.5	2.1
Respiratory disease	1.1	2.5	4.8	-1.9	-1.0	-1.3	-1.9	-1.4	-1.8	-0.8	-1.8	-2.2	-1.3
Tanning	1.1	13.3	18.7	3.9	3.9	3.7	3.7	4.3	3.6	3.7	3.8	4.0	-0.2
Diabetes (mother)	1.1	1.5	6.5	-1.1	-1.3	-0.5	-1.0	-1.2	-0.9	-0.3	-1.1	-0.8	-2.5
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	2.6	1.0	1.6	1.4	0.9	0.4	0.8	0.8	1.0	1.1	-1.4
Stomach or abdominal pain in last month	1.1	1.3	2.5	-1.3	-1.0	-1.1	-1.3	-0.5	-1.4	-0.2	-1.4	-1.6	-1.0
Forced vital capacity (FVC)	1.1	4.3	9.7	1.6	2.9	2.0	1.5	2.1	1.5	3.1	1.5	2.1	1.8
Weight	1.1	5.2	8.5	-2.8	-2.5	-0.8	-2.9	-2.2	-2.9	-1.2	-2.9	-2.0	-1.6
Hair/balding pattern: Pattern 3	1.1	1.6	2.6	1.1	1.3	0.9	1.2	1.1	1.2	1.4	1.2	1.4	1.6
Tense / ‘highly strung’	1.1	1.9	2.9	-1.5	1.7	-0.9	-1.6	-1.5	-1.5	-0.8	-1.7	-1.2	-0.8
Gout (self-reported)	1.1	1.5	4.4	-1.3	-0.8	-0.5	-1.4	-2.1	-1.2	-1.2	-1.4	-0.8	-0.7
Smoking status: Previous	1.1	1.6	2.8	1.2	1.7	1.3	1.2	1.4	1.2	1.2	1.3	1.4	-0.1
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	3.3	1.2	1.8	1.6	1.2	0.8	1.3	1.2	1.1	1.7	-1.2
Illnesses of father: None of the above (group 1)	1.1	1.4	4.6	-1.1	-2.1	-0.3	-1.1	-0.3	-1.1	-0.8	-1.2	-1.5	1.2
Financial situation satisfaction	1.1	1.4	6.0	-0.2	2.0	-0.2	-0.5	-0.6	-0.4	0.8	-0.5	1.3	-2.5
Illnesses of father: High blood pressure	1.1	1.3	3.6	-0.9	1.9	-1.8	-1.0	-0.8	-1.1	-1.1	-0.9	0.4	0.8
Leg fat percentage (left)	1.1	4.1	7.3	-2.3	-0.8	-1.1	-2.6	-2.3	-2.7	-1.3	-2.5	-1.4	-2.2
Bipolar Disorder or Schizophrenia	1.0	2.4	4.2	-1.7	-0.5	-0.7	-2.0	-1.8	-2.1	-1.3	-2.0	-1.3	-1.2
Depression (Nagel 2018)	1.0	1.5	3.0	-1.3	-0.4	-1.3	-1.3	-1.3	-1.2	-0.9	-1.4	-0.8	-1.7
Prostate Cancer	1.0	1.4	3.8	1.1	1.9	0.6	0.8	1.5	0.9	0.7	0.8	1.9	0.7
Medication for hormone replacement therapy	1.0	1.1	5.6	-0.4	-0.5	-0.3	-0.5	-2.4	-0.5	-1.5	-0.5	-0.0	1.4
Fed-up feelings	1.0	1.9	7.6	0.5	2.8	0.2	0.2	0.2	0.2	0.9	0.3	2.2	-2.3
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.7	-1.3	-0.5	-1.0	-1.2	-1.2	-1.2	-0.3	-1.2	-1.2	0.5
Past tobacco smoking	1.0	1.9	3.5	-1.3	-1.9	-1.3	-1.2	-1.4	-1.2	-1.5	-1.3	-1.5	1.0
Arm fat mass (right)	1.0	4.2	8.1	-2.5	-1.1	-1.2	-2.8	-1.9	-2.9	-1.3	-2.7	-1.6	-1.3
Standing height	1.0	10.2	44.4	-2.9	-6.7	-1.1	-2.4	-2.6	-2.3	-2.1	-2.7	-4.1	0.8
Loud music exposure frequency	1.0	1.1	3.6	0.5	1.7	0.5	0.8	-0.2	0.6	1.1	0.8	0.8	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	2.1	-1.3	-0.2	-0.9	-1.1	-1.2	-1.1	-0.8	-1.0	-1.5	-1.2
Arm fat mass (left)	1.0	4.1	8.1	-2.5	-1.1	-1.1	-2.8	-1.9	-2.9	-1.3	-2.7	-1.5	-1.3
Alcohol drinker status: Never	1.0	1.2	2.6	-1.3	-1.6	-0.5	-1.1	-0.1	-1.2	-0.3	-1.2	-1.6	-0.8
Ever used hormone-replacement therapy (HRT)	0.9	1.2	2.5	1.1	1.2	1.6	0.8	-0.8	0.8	1.4	0.9	0.9	-0.8
High blood pressure (mother)	0.9	1.2	3.5	-1.1	-0.8	-1.3	-1.1	-0.6	-1.2	-1.9	-1.0	-1.1	-0.5
Financial difficulties in last 2 years	0.9	1.2	4.1	-0.9	1.5	-0.4	-1.0	-1.2	-0.9	-0.2	-1.0	0.9	-2.0
Number of live births	0.9	1.3	2.5	-1.1	0.5	-1.0	-1.2	-1.6	-1.1	-1.3	-1.2	-1.1	-0.7
Medication: Lansoprazole	0.9	1.0	2.6	-1.5	-0.7	-0.6	-0.9	-0.2	-1.3	0.7	-0.9	-1.6	0.8
Pulse wave reflection index	0.9	1.2	5.2	-0.7	-0.9	-1.5	-0.7	0.2	-0.6	-2.3	-0.8	-0.9	0.8
Alcohol intake frequency.	0.9	2.0	6.4	-1.4	-2.5	-0.7	-1.1	-1.2	-1.1	-1.3	-1.1	-1.9	0.8
Miserableness	0.9	1.6	8.5	-0.6	2.9	-0.1	-0.5	-0.9	-0.7	1.1	-0.5	0.6	-1.9
Hearing aid user	0.9	1.0	4.4	1.0	-0.0	0.6	1.0	0.1	0.9	1.3	1.0	0.1	-2.1
Irritability	0.9	1.6	2.9	-1.3	1.7	-1.2	-1.1	-1.3	-1.1	-1.6	-1.1	-0.3	-1.4
Myopia	0.9	1.4	3.3	-1.3	-0.5	-1.8	-1.4	-0.5	-1.3	-1.7	-1.2	-0.5	-0.2
Alzheimer’s Disease (including proxy)	0.8	1.2	5.3	0.7	2.3	0.0	0.3	0.1	0.4	1.0	0.3	2.2	-0.3
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	2.4	0.7	-1.0	1.5	0.8	0.3	0.8	1.4	0.8	-0.7	-1.6
Vitamin and mineral supplements	0.8	1.1	2.5	-1.3	0.0	-1.6	-1.3	-0.8	-1.3	-0.9	-1.2	-0.4	0.4
Hand grip strength (right)	0.8	2.2	3.2	-1.8	-0.9	-1.8	-1.7	-0.9	-1.7	-1.6	-1.7	-1.1	-1.0
Taking other prescription medications	0.8	1.3	3.5	-1.2	-0.6	-0.3	-0.8	-1.2	-1.0	1.5	-1.0	-1.0	-1.9
Medication: Simvastatin	0.8	1.2	2.6	-1.4	-0.8	-0.9	-1.0	-1.2	-1.2	-1.6	-1.1	-1.0	0.1
Arm fat percentage (right)	0.8	3.1	6.1	-2.1	-0.6	-1.1	-2.4	-1.6	-2.5	-1.3	-2.3	-1.5	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	5.3	-1.0	1.6	-0.7	-0.9	-0.4	-1.0	0.1	-0.9	-0.4	-2.3
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.2	0.9	0.6	0.9	1.0	0.4	1.0	1.4	1.0	0.7	-1.5
Suffer from ‘nerves’	0.8	1.3	2.6	-1.2	1.6	-0.6	-1.2	-1.0	-1.2	0.3	-1.3	-1.1	-1.2
Medication: Aspirin	0.8	1.1	1.9	-1.4	-0.2	-1.0	-1.2	-1.2	-1.2	-0.9	-1.2	-0.8	-0.6
Average weekly red wine intake	0.8	1.2	2.7	-1.1	-0.5	-1.0	-1.2	-1.0	-1.2	-0.9	-1.2	-1.6	-0.3
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.0	1.1	0.9	1.2	0.9	1.4	1.1	1.1	0.9	0.5	0.5
Mood swings	0.8	1.4	13.2	-0.1	0.5	0.3	0.1	0.1	-0.1	-0.0	0.1	0.3	-3.6
Ever depressed for a whole week	0.8	1.0	5.0	-0.8	-0.3	-0.4	-0.4	-1.4	-0.5	-0.0	-0.5	-1.2	-2.2
Unable to work because of sickness or disability	0.8	1.1	4.5	0.8	1.1	1.1	0.9	0.9	0.7	2.1	0.9	0.4	0.6
Cholesterol lowering medication	0.8	1.2	2.4	-1.3	-1.6	-0.6	-0.9	-1.3	-1.1	-1.0	-1.0	-1.3	0.6
Alcohol drinker status: Previous	0.8	0.9	3.5	0.8	-1.9	0.8	1.1	0.7	1.1	0.4	1.1	0.2	0.2
Depressed Affect (Nagel 2018)	0.7	1.5	7.0	0.5	2.6	0.4	0.4	0.8	0.4	0.7	0.5	1.3	-2.2
Alzheimer’s Disease (in father)	0.7	0.7	3.0	1.0	1.7	0.3	0.7	0.0	0.9	0.2	0.7	1.0	-0.3
Height	0.7	12.7	59.6	-3.4	-7.7	-0.9	-2.4	-2.9	-2.4	-1.7	-2.8	-4.5	2.1
Sensitivity / hurt feelings	0.7	1.1	3.3	-0.9	-0.7	-1.3	-0.8	-1.8	-0.9	0.1	-0.8	-0.9	-1.4
Systolic blood pressure, automated reading	0.7	2.0	5.0	-1.4	-0.1	-0.9	-1.6	-1.1	-1.7	-2.2	-1.4	-0.8	-1.8
Medication: Ramipril	0.7	1.0	5.7	-0.4	0.6	0.3	-0.7	-1.2	-0.7	-0.0	-0.6	0.5	-2.4
Hair/balding pattern: Pattern 4	0.7	1.7	8.9	0.7	-3.0	0.6	1.0	0.9	0.8	-1.3	1.0	-0.2	1.4
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.6	-1.2	-0.2	-0.5	-1.1	-0.8	-1.1	-0.3	-1.2	-1.6	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.7	-0.1	0.4	-1.4	-0.5	-0.8	-0.3	-1.9	-0.5	0.3	-0.7
Supplements: Vitamin C	0.7	0.8	3.3	0.4	-0.5	1.3	0.6	0.1	0.5	1.1	0.6	-0.3	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.1	-1.1	-0.5	-0.4	-0.9	-1.4	-1.1	1.1	-0.8	-0.9	-0.2
Arm fat percentage (left)	0.7	2.6	5.5	-1.9	-0.4	-1.1	-2.3	-1.5	-2.3	-1.1	-2.2	-1.1	-0.9
Medication for cholesterol	0.7	1.1	4.1	0.9	0.3	0.4	0.9	2.0	0.9	2.0	0.8	0.3	0.1
Ever smoked	0.7	1.1	5.4	0.7	1.5	0.5	0.4	0.5	0.5	0.8	0.5	1.2	-2.3
Arm fat-free mass (left)	0.7	3.4	6.4	-2.2	-2.5	-0.4	-2.2	-1.6	-2.2	-0.8	-2.2	-1.4	-1.9
Alzheimer’s Disease (in mother)	0.6	0.8	3.4	-0.2	1.8	-0.9	-0.4	-0.2	-0.3	0.3	-0.4	1.6	-0.6
Ovarian Cancer	0.6	0.8	1.0	0.8	1.0	1.0	1.0	0.8	0.8	0.4	1.0	1.0	0.9
Mean Putamen Volume	0.6	0.7	1.4	0.8	-0.4	0.8	1.2	0.6	1.1	0.4	1.2	0.4	0.9
Blood Eosinophil Count	0.6	4.5	9.8	-1.9	-3.1	-1.6	-1.7	-2.2	-1.6	-2.2	-1.8	-2.6	2.0
BMI	0.6	3.3	7.5	-2.3	0.2	-1.3	-2.6	-1.9	-2.7	-0.7	-2.4	-0.7	-1.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	5.4	-0.4	0.0	-0.6	-0.5	-1.1	-0.4	0.2	-0.6	0.1	-2.3
Angina	0.6	0.8	5.9	0.2	0.3	0.8	0.1	-0.3	0.1	0.8	0.2	-0.1	-2.4
Severe depression (siblings)	0.6	0.7	3.6	0.1	0.0	0.6	0.2	1.1	0.1	1.1	0.3	-0.6	-1.9
Leg fat-free mass (left)	0.6	3.2	5.4	-2.3	-2.3	-0.8	-2.2	-1.2	-2.3	-0.8	-2.2	-1.7	-1.0
Qualifications: CSEs or equivalent	0.6	0.8	1.5	-1.2	-0.1	-0.9	-1.0	-0.6	-0.9	-1.1	-1.1	-0.5	-0.9
Leg predicted mass (left)	0.6	3.1	5.2	-2.3	-2.2	-0.7	-2.2	-1.2	-2.2	-0.8	-2.2	-1.7	-1.0
Number of incorrect matches in round	0.6	0.9	2.1	1.1	-0.1	1.5	1.2	0.7	1.3	-0.9	1.2	0.2	-0.3
Had other major operations	0.6	0.7	1.5	-0.9	0.7	-0.8	-1.2	-0.2	-1.2	-1.1	-1.0	-0.3	0.4
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.5	0.5	1.6	0.6	0.8	0.1	0.6	0.4	0.8	0.3	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	5.9	-0.4	0.7	0.7	-0.3	-0.5	-0.4	1.2	-0.3	-0.1	-2.4
Depression (self-reported)	0.6	0.7	4.4	0.2	2.1	-0.6	0.2	0.6	0.2	0.7	0.4	0.4	-1.2
Arm fat-free mass (right)	0.6	3.3	6.1	-2.3	-2.5	-0.5	-2.2	-1.6	-2.2	-0.7	-2.2	-1.3	-1.4
Age at first live birth	0.6	1.1	5.0	-0.6	1.1	-1.3	-0.6	0.5	-0.6	-1.2	-0.6	-0.3	2.2
Arm predicted mass (right)	0.6	3.0	5.8	-2.2	-2.4	-0.4	-2.1	-1.4	-2.1	-0.5	-2.1	-1.3	-1.4
Knee pain experienced in last month	0.6	0.9	4.7	-0.9	-2.2	-0.6	-0.6	-1.0	-0.8	0.5	-0.6	-0.8	-0.4
Qualifications: nursing, teaching	0.6	0.9	3.0	-0.5	-0.4	-0.9	-0.6	-1.0	-0.5	-1.2	-0.6	-1.1	-1.7
Back pain experienced in last month	0.6	0.9	2.0	-1.0	-0.7	-1.0	-0.9	-1.2	-1.0	-0.4	-0.9	-0.5	-1.4
Medication: Paracetamol	0.6	1.0	3.2	-0.8	0.3	-0.6	-0.9	-1.0	-1.0	-1.5	-0.8	0.3	-1.8
Basal metabolic rate	0.6	3.4	6.9	-2.2	-2.6	-0.4	-2.2	-1.5	-2.2	-0.8	-2.2	-1.6	-1.3
Diastolic blood pressure, automated reading	0.6	2.0	3.7	-1.4	-1.1	-1.2	-1.5	-1.1	-1.5	-1.7	-1.5	-1.1	-1.9
Arm predicted mass (left)	0.6	2.8	5.8	-2.1	-2.4	-0.1	-2.0	-1.1	-2.0	-0.6	-2.0	-1.3	-1.7
Ulcerative Colitis (UC)	0.5	0.9	3.8	-0.3	-2.0	0.8	-0.4	-0.7	-0.4	-1.3	-0.5	-1.1	0.3
Blood Red Count	0.5	4.9	26.1	-1.1	-5.1	-0.8	-1.2	-1.7	-1.2	-3.2	-1.2	-1.8	-0.1
Hearing difficulty/problems: Yes	0.5	0.8	3.5	-0.4	-0.7	-0.3	-0.6	-1.2	-0.5	-0.8	-0.6	-0.4	-1.9
Pack years adult smoking proportion	0.5	0.7	2.1	-0.6	-1.2	-0.2	-0.4	-1.1	-0.5	0.4	-0.4	-1.2	-1.4
Maternal smoking around birth	0.5	0.8	1.4	-0.9	0.6	-1.2	-1.1	-0.7	-1.2	0.3	-0.9	-0.2	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.7	-0.8	-0.8	-0.8	-0.8	-0.9	-0.7	-0.5	-0.9	-0.2	-1.3
Hayfever, allergic rhinitis or eczema	0.5	1.2	7.6	0.7	0.8	0.7	0.9	0.7	0.7	2.8	0.8	-0.1	-0.3
Medication: Levothyroxine sodium	0.5	0.8	1.9	0.7	0.6	1.4	0.8	0.9	0.7	1.1	0.7	0.4	1.1
Body mass index (BMI)	0.5	2.2	4.8	-1.7	0.4	-0.6	-2.0	-1.2	-2.1	-0.5	-1.8	-0.3	-2.2
Trunk fat-free mass	0.5	2.8	11.2	-1.7	-3.3	-0.1	-1.6	-1.2	-1.6	-0.5	-1.7	-1.5	-1.2
Alcohol intake versus 10 years previously	0.5	0.7	1.3	-0.9	-0.1	-0.9	-0.9	-1.1	-0.8	-0.9	-0.8	-1.1	-0.5
Father’s age at death	0.5	0.7	1.4	0.9	0.7	0.3	1.2	0.6	1.1	0.7	1.2	0.3	0.5
Pulse rate	0.5	0.8	4.2	-0.6	-0.6	0.3	-0.4	-0.8	-0.4	2.0	-0.5	0.9	-1.1
Medication: Cholesterol lowering	0.5	0.8	1.4	-1.1	-1.0	-0.5	-0.9	-0.7	-0.9	-0.8	-0.9	-1.2	0.3
Trunk predicted mass	0.5	2.7	11.6	-1.7	-3.4	-0.0	-1.5	-1.2	-1.5	-0.5	-1.6	-1.4	-1.2
Birth weight of first child	0.5	0.8	1.9	-1.2	-0.5	-0.7	-1.0	-0.7	-0.9	-1.4	-1.1	-0.8	0.2
Blood clot in the leg (DVT)	0.5	0.6	3.3	-0.4	0.4	-0.0	-0.4	0.6	-0.5	0.8	-0.4	-0.9	1.8
Worry too long after embarrassment	0.5	0.8	3.3	-0.7	-0.4	-0.4	-0.7	-1.8	-0.7	1.2	-0.8	-0.5	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	5.6	0.6	-2.4	1.5	0.7	-0.1	0.7	1.0	0.6	0.2	0.4
Loneliness, isolation	0.5	0.7	4.0	0.0	1.6	0.0	-0.2	-0.5	-0.1	-0.0	-0.2	0.7	-2.0
Commuting to job workplace: Walk	0.5	0.6	1.5	0.8	1.0	0.9	0.5	-0.1	0.8	0.1	0.6	1.2	0.6
Medication: Lisinopril	0.5	0.6	3.2	-0.1	-1.8	0.4	0.2	-0.9	0.2	-0.8	0.0	-1.0	0.4
Average weekly beer plus cider intake	0.5	0.7	2.7	-0.4	-1.0	0.3	-0.7	-1.7	-0.4	0.8	-0.7	-0.2	-1.2
Fractured/broken bones in last 5 years	0.5	0.6	2.7	-0.4	-1.6	0.1	-0.3	-0.6	-0.5	0.2	-0.4	-1.5	-0.0
Basal cell carcinoma (self-reported)	0.5	0.5	1.1	0.7	0.5	0.9	0.9	1.0	0.7	0.7	0.9	0.5	-0.2
Heart disease (siblings)	0.5	0.6	1.7	-1.1	-0.4	-0.4	-0.9	-0.0	-1.0	-0.4	-0.9	-1.3	-0.0
Neuroticism (Nagel 2018)	0.4	0.8	4.4	-0.0	1.7	0.4	0.1	-0.1	0.1	0.8	-0.0	0.2	-2.1
Schizophrenia (2018)	0.4	0.7	1.3	-1.0	-0.9	0.1	-1.0	-1.1	-1.1	-0.1	-1.0	-0.5	-0.8
Verbal and Numeric Reasoning (VNR)	0.4	0.9	4.0	-0.6	-0.0	-1.4	-0.9	0.3	-0.9	-0.3	-0.9	-0.1	2.0
Crohns Disease (2012)	0.4	0.6	1.4	-0.9	-0.0	-0.8	-0.7	-1.2	-0.8	-0.4	-0.7	-0.7	-1.2
HDL Cholesterol	0.4	0.7	1.4	1.0	-0.7	1.1	1.1	0.4	1.0	0.5	1.2	0.1	0.5
LDL Cholesterol	0.4	0.6	3.2	0.3	1.8	-0.2	-0.0	1.6	-0.0	0.3	-0.0	0.2	-0.1
Neuroticism (2016)	0.4	0.6	1.3	-0.8	1.1	-0.3	-1.0	-0.7	-0.9	-0.3	-1.0	0.4	0.8
Blood White Count	0.4	3.3	5.3	-2.1	-1.9	-0.9	-2.1	-2.3	-1.9	-2.1	-2.3	-1.2	-0.4
Heel T-Score	0.4	3.6	12.6	2.2	1.4	-0.2	1.7	1.4	1.8	-2.0	2.0	3.5	0.5
Hair Pigment	0.4	11.4	22.4	-3.3	-4.7	-3.6	-3.0	-3.5	-2.9	-3.4	-3.1	-4.0	0.4
Average weekly spirits intake	0.4	0.5	0.9	-0.8	0.2	-0.5	-0.6	0.9	-0.8	-0.8	-0.6	-0.7	0.9
Medication: Co-codamol	0.4	0.5	2.8	-0.3	0.3	0.2	-0.3	0.9	-0.5	0.2	-0.3	-0.8	-1.7
Medication: Metformin	0.4	0.5	1.6	-1.1	0.3	-0.6	-0.7	0.2	-0.8	0.2	-0.7	0.2	1.3
Impedance of leg (right)	0.4	1.9	5.3	-0.7	-2.3	-0.7	-0.7	-2.0	-0.5	-1.5	-0.8	-2.2	0.4
Current tobacco smoking	0.4	0.7	1.2	-0.9	-0.2	-1.1	-1.1	-0.8	-1.0	-0.7	-1.0	-0.1	-0.8
Relative age voice broke	0.4	0.6	1.0	0.9	-0.4	0.9	1.0	-0.1	1.0	0.9	1.0	0.5	-0.3
Chronic bronchitis/emphysema (father)	0.4	0.5	1.2	-0.7	0.5	-0.8	-0.8	-1.1	-0.8	-0.4	-0.7	-0.5	0.4
Allergy	0.4	0.8	2.3	1.0	0.1	0.3	0.8	0.2	1.0	-1.4	0.9	1.5	0.5
Diabetes (self-reported)	0.4	0.7	4.2	-0.1	-0.4	0.2	0.5	0.8	0.4	1.1	0.4	0.1	2.0
Fluid intelligence score	0.4	0.8	5.4	0.5	0.4	-0.4	0.4	0.5	0.4	0.5	0.4	0.9	2.3
Falls in the last year	0.4	0.6	2.9	-0.1	-0.8	0.3	-0.0	-0.8	-0.1	1.7	-0.1	-1.0	0.5
Noisy workplace	0.4	0.5	1.6	-0.7	-0.2	-0.6	-0.5	-1.3	-0.7	1.1	-0.5	-0.4	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.3	0.5	-0.3	1.2	0.5	0.8	0.5	1.2	0.5	0.5	-0.3
Peak expiratory flow (PEF)	0.4	0.8	2.9	0.4	1.3	0.9	0.3	1.1	0.2	1.7	0.4	0.8	0.9
Medication: Paracetamol	0.4	0.6	4.4	-0.2	0.5	0.1	-0.3	-0.1	-0.4	-0.9	-0.3	0.6	-2.1
Angina (self-reported)	0.4	0.6	4.7	0.0	0.1	0.7	0.0	-0.6	-0.0	0.5	0.0	-0.3	-2.2
Mean time to correctly identify matches	0.4	0.9	7.1	0.2	0.9	-0.2	0.4	-0.1	0.2	0.2	0.5	0.3	2.7
Heart disease (mother)	0.4	0.5	2.5	-0.4	-1.6	-0.5	-0.0	-0.4	-0.2	-0.3	-0.0	-1.2	-0.3
Pulse rate, automated reading	0.4	1.2	4.6	-0.7	-1.3	-0.1	-0.4	-0.6	-0.4	2.1	-0.5	-0.0	-2.1
Number of full sisters	0.4	0.5	1.3	-0.7	-1.2	-0.2	-0.8	-1.1	-0.8	-0.1	-0.8	-0.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.4	-0.7	-0.4	-0.2	-0.7	-1.0	-0.7	0.6	-0.7	-0.0	-1.2
Illnesses of father: Heart disease	0.4	0.6	5.1	-0.5	0.5	-0.6	-0.2	0.2	-0.2	0.2	-0.3	-0.3	-2.2
Whole body fat-free mass	0.4	2.4	7.2	-1.9	-2.7	-0.1	-1.8	-1.1	-1.8	-0.5	-1.8	-1.4	-1.1
Ever had bowel cancer screening	0.4	0.5	1.3	-0.4	-1.1	-0.6	-0.4	-0.6	-0.4	-1.0	-0.4	-1.1	0.2
Breast cancer (self-reported)	0.4	0.5	1.3	0.2	-1.1	0.3	0.4	0.9	0.4	-0.9	0.4	-1.0	0.4
Osteoarthritis (self-reported)	0.4	0.5	1.3	-0.7	-1.1	-0.6	-0.6	-0.3	-0.7	-0.4	-0.7	-0.6	1.1
Whole body water mass	0.4	2.5	7.1	-1.9	-2.7	-0.1	-1.8	-1.1	-1.8	-0.5	-1.8	-1.4	-1.1
Average weekly champagne plus white wine intake	0.4	0.5	1.0	1.0	-0.1	1.0	0.9	0.2	1.0	-0.1	0.9	0.8	0.1
Ever taken oral contraceptive pill	0.4	0.4	1.1	0.3	0.8	0.3	0.3	-1.0	0.3	1.1	0.3	0.8	0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.7	-0.4	0.5	0.1	-0.4	0.7	-0.5	1.0	-0.4	-0.8	1.3
Schizophrenia vs Biploar Disorder	0.3	0.5	1.6	-0.1	-1.2	0.6	0.2	-0.0	0.1	0.9	0.2	0.4	1.3
Crohns Disease (2017)	0.3	0.7	1.1	-0.9	-0.9	-0.7	-0.7	-0.8	-0.7	-0.9	-0.7	-1.0	-0.8
Irritable Bowel Disease (IBD)	0.3	0.7	3.4	-0.4	-1.8	0.2	-0.4	-0.6	-0.3	-1.0	-0.5	-1.1	-0.5
Systolic Blood Pressure	0.3	1.4	4.5	-1.0	0.4	-0.8	-1.0	-0.9	-1.1	-2.1	-0.9	-0.8	-1.7
Lung FEV1/FVC ratio	0.3	1.5	6.2	-0.3	1.5	0.5	-0.4	1.0	-0.5	2.5	-0.4	1.8	1.3
Neuroticism	0.3	0.7	2.4	0.6	1.5	0.9	0.7	0.1	0.7	1.1	0.7	0.6	-0.8
Diabetes (father)	0.3	0.4	2.7	-0.4	0.8	-0.2	-0.2	-0.4	-0.2	-0.2	-0.3	-0.2	-1.6
Multivitamins +/- minerals	0.3	0.4	1.0	0.6	-0.4	1.0	0.7	0.6	0.7	0.4	0.7	0.1	0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.1	0.6	1.0	0.1	0.6	0.2	0.7	-0.4	0.6	0.4	-0.5
Medication: Atenolol	0.3	0.4	1.9	0.3	-0.1	0.1	0.3	0.6	0.3	-0.7	0.3	-0.6	-1.4
Alcohol usually taken with meals	0.3	0.6	1.3	0.7	-0.2	0.7	1.0	0.1	0.8	0.8	1.0	-0.1	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.2	-0.7	0.4	0.0	-0.6	-1.5	-0.7	0.3	-0.6	0.1	-0.5
Hearing difficulty/problems with background noise	0.3	0.5	3.0	0.1	-1.3	0.4	0.0	-0.3	0.0	-0.1	0.0	-0.0	-1.7
Heart attack	0.3	0.4	2.2	0.4	0.4	0.2	0.6	0.2	0.6	0.1	0.5	-0.2	-1.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.9	0.8	-0.2	0.5	0.9	0.1	0.8	0.9	0.9	-0.2	0.2
Illnesses of siblings	0.3	0.4	1.7	0.0	-0.7	-0.6	-0.0	-0.6	0.1	-0.8	-0.1	-0.3	-1.3
Neuroticism score	0.3	0.6	2.7	-0.0	1.6	0.1	0.0	-0.7	0.0	0.5	-0.0	0.2	-1.7
Impedance of arm (right)	0.3	1.3	4.9	-0.4	-1.6	-0.6	-0.3	-0.7	-0.2	-1.0	-0.5	-2.2	1.8
Worrier / anxious feelings	0.3	0.5	1.7	0.0	-1.1	-0.0	0.2	-1.3	0.2	0.8	0.1	-0.3	1.0
Illnesses of mother	0.3	0.4	1.5	0.2	-1.0	0.7	0.4	-0.5	0.4	0.3	0.2	-0.6	1.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.1	0.8	0.9	0.4	0.9	-0.1	0.9	1.1	0.8	0.4	0.2
Headache pain in last month	0.3	0.6	1.1	-0.9	0.5	-0.7	-1.0	-0.9	-1.0	-0.4	-1.0	-0.4	-0.4
Comparative body size at age 10	0.3	0.9	2.7	-1.0	-0.5	-1.4	-0.7	-1.0	-0.8	-1.6	-0.6	-0.7	0.7
Medication: Seretide 50 evohaler	0.3	0.3	0.7	-0.6	-0.6	-0.0	-0.6	-0.0	-0.7	-0.7	-0.5	-0.8	-0.5
Had major operations	0.3	0.3	1.3	-0.0	0.3	1.1	-0.1	-0.3	-0.1	0.9	-0.2	-0.1	-1.1
Illnesses of siblings: Diabetes	0.3	0.4	1.8	0.1	-0.4	1.3	0.3	-0.4	0.2	1.0	0.3	-0.6	-0.4
Leg fat-free mass (right)	0.3	1.9	3.5	-1.9	-1.7	-0.3	-1.8	-0.7	-1.8	-0.4	-1.8	-1.1	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.1	-0.5	1.1	-0.2	-0.6	0.0	-0.5	-0.2	-0.6	-0.7	-0.7
Friendships satisfaction	0.3	0.4	1.2	-0.4	1.0	0.3	-0.6	-0.9	-0.6	-0.0	-0.5	-0.2	-1.1
Osteoporosis (self-reported)	0.3	0.4	1.3	0.7	-0.1	0.7	0.6	0.3	0.6	0.9	0.6	-0.1	-1.1
Leg predicted mass (right)	0.3	1.8	3.3	-1.8	-1.7	-0.3	-1.8	-0.7	-1.8	-0.3	-1.8	-1.1	-0.7
Medication: Blood pressure	0.3	0.5	3.6	-0.1	-0.8	0.0	-0.0	-0.1	-0.1	-0.8	-0.0	-0.3	-1.9
Number of operations (self-reported)	0.3	0.5	1.7	-0.6	-1.3	0.3	-0.7	-0.6	-0.8	0.3	-0.7	-0.3	0.1
Commuting to job workplace: Cycle	0.3	0.4	1.1	0.4	-0.4	0.9	0.6	0.7	0.5	0.4	0.7	-0.3	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.0	-0.6	-0.7	-0.0	-0.5	-1.0	-0.4	0.8	-0.5	-0.8	-0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.4	0.6	0.4	0.4	0.7	0.4	0.7	0.2	0.7	0.1	-1.2
Pack years of smoking	0.3	0.4	1.2	-0.3	-0.8	0.0	-0.1	-0.9	-0.2	0.7	-0.1	-0.9	-1.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.8	-0.5	-1.0	-1.0	-0.7	0.2	-0.7	-0.3	-0.7	-0.1	1.7
Age at First Birth	0.2	0.3	1.9	0.2	1.4	0.3	-0.2	-0.1	-0.1	-0.7	-0.1	0.0	0.1
Primary Biliary Cirrhosis	0.2	0.3	0.7	-0.7	-0.6	0.3	-0.8	-0.0	-0.7	0.4	-0.8	-0.5	-0.4
Rheumatoid Arthritis	0.2	0.3	1.4	0.2	-0.3	-0.6	0.6	-0.2	0.4	1.2	0.6	-0.3	-0.2
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.7	-0.5	0.8	-0.0	-0.1	-0.8	-0.1	-0.2	-0.1	0.3	-0.4
Ulcerative Colitis	0.2	0.3	1.1	0.4	-1.0	1.1	0.5	-0.3	0.4	0.4	0.4	-0.3	-0.6
Hypothyroidism (self reported)	0.2	0.4	2.2	-0.2	0.3	0.8	-0.0	0.3	-0.2	0.8	-0.1	0.3	1.5
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.0	-0.6	-0.9	-0.3	0.1	0.3	0.0	0.7	-0.1	0.3	1.0
Chronotype (morning person)	0.2	0.5	3.4	-0.5	-1.8	0.4	-0.3	-0.6	-0.2	-0.6	-0.5	-0.6	0.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.9	-0.4	0.0	-0.5	-0.1	-0.3	-0.2	0.5	-0.1	-0.2	1.0
Impedance of leg (left)	0.2	0.9	2.9	-0.4	-1.5	-0.3	-0.5	-1.7	-0.3	-1.0	-0.6	-1.3	0.4
Nervous feelings	0.2	0.4	1.7	-0.0	0.5	0.9	0.3	-0.9	0.3	1.3	0.1	-0.7	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.3	-0.4	-0.4	-0.4	-0.6	-0.4	-0.5	-1.2	-0.5	1.2	-0.2
Hip circumference	0.2	0.7	3.6	-0.6	-0.1	1.0	-0.8	-0.3	-0.8	0.7	-0.7	-0.1	-1.9
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.0	-0.5	-0.1	-1.4	-0.5	-0.6	-0.4	-1.0	-0.5	-0.7	0.5
Impedance of arm (left)	0.2	1.1	5.1	0.1	-1.5	-0.5	0.1	-0.5	0.3	-0.8	-0.0	-1.5	2.3
Exposure to tobacco smoke at home	0.2	0.2	0.6	-0.4	0.6	0.3	-0.5	-0.1	-0.5	-0.4	-0.4	0.0	0.8
Breastfed as a baby	0.2	0.3	1.0	0.2	-0.6	0.4	0.2	0.8	0.3	0.1	0.2	-0.4	1.0
Medication: Amlodipine	0.2	0.3	0.8	0.3	0.6	0.1	0.3	0.9	0.3	0.6	0.4	0.6	-0.7
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.3	0.6	0.4	0.5	0.5	0.5	0.5	0.2	0.6	0.5	0.5
High blood pressure (siblings)	0.2	0.3	0.5	-0.5	0.7	-0.3	-0.7	-0.2	-0.7	-0.6	-0.6	0.6	0.5
Number of full brothers	0.2	0.3	1.0	-0.6	1.0	-0.1	-0.6	-0.1	-0.5	0.5	-0.6	-0.3	0.3
Qualifications: College or University degree	0.2	0.7	2.7	0.6	-0.7	0.3	0.4	1.4	0.5	-0.5	0.5	0.4	1.7
Emphysema/chronic bronchitis	0.2	0.3	1.5	-0.3	-0.6	-0.2	-0.3	-0.1	-0.4	0.5	-0.3	-1.2	0.0
Medication for pain relief, constipation, heartburn	0.2	0.4	1.0	0.7	-0.4	-0.3	0.6	0.5	0.7	-0.6	0.7	-0.1	1.0
Migraine (self-reported)	0.2	0.3	1.1	-0.1	-1.0	-0.1	0.0	-0.3	0.0	-0.5	-0.1	-1.0	-0.3
Chest pain or discomfort	0.2	0.2	1.0	-0.2	1.0	0.5	-0.2	-0.5	-0.2	0.1	-0.3	-0.0	-0.8
Diabetes diagnosed by doctor	0.2	0.3	0.8	-0.9	-0.4	-0.6	-0.4	-0.4	-0.5	0.5	-0.5	-0.4	0.8
Wears glasses or contact lenses	0.2	0.2	0.4	-0.6	0.2	-0.2	-0.6	-0.5	-0.6	-0.2	-0.6	-0.7	-0.2
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.7	-0.3	0.3	-0.8	-0.6	0.5	-0.4	-0.7	-0.5	-0.0	-0.3
Commuting to job workplace: Public transport	0.2	0.3	1.4	0.5	0.5	-0.0	0.2	1.2	0.2	-0.6	0.2	-0.3	0.1
Risk taking	0.2	0.3	1.3	0.4	0.4	0.1	0.2	-0.2	0.2	0.5	0.2	1.1	-0.7
Impedance of whole body	0.2	1.1	2.7	-0.3	-1.6	-0.5	-0.3	-1.2	-0.2	-1.2	-0.4	-1.7	1.5
Worry (Nagel 2018)	0.1	0.3	1.1	-0.4	0.1	0.2	-0.3	-0.6	-0.3	0.3	-0.5	-1.0	-0.6
Fasting Glucose	0.1	0.1	0.2	-0.4	-0.1	-0.4	-0.3	0.3	-0.4	0.1	-0.3	-0.1	0.2
Blood Platelet Count	0.1	0.7	3.0	-0.2	0.4	0.8	-0.7	-0.2	-0.4	-1.2	-0.7	-0.9	-1.7
Relative age of first facial hair	0.1	0.2	1.0	-0.2	-1.0	0.2	-0.1	0.1	-0.1	0.0	-0.1	-0.8	0.1
Supplements: Zinc	0.1	0.1	0.5	-0.0	-0.3	-0.1	0.1	-0.7	0.1	0.1	0.1	-0.6	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.3	0.1	-0.4	-0.1	-0.2	0.2	-0.1	-0.7	-0.1	1.1	-0.4
Sitting height	0.1	0.8	3.1	0.4	-1.4	1.8	0.4	0.1	0.5	0.8	0.3	0.7	-1.0
Qualifications: None of the above	0.1	0.2	1.0	0.1	1.0	0.7	-0.1	0.3	-0.1	-0.1	0.0	0.3	-0.7
Time employed in main current job	0.1	0.1	0.3	0.4	0.5	0.1	0.2	0.4	0.3	-0.3	0.2	0.4	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.6	-0.3	-0.0	-0.6	-0.3	-0.2	-0.2	0.4	-0.4	-0.4	-0.8
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	-0.3	0.2	-0.4	-0.6	0.4	-0.6	-0.6	-0.6	0.3	-0.3
Lung cancer (father)	0.1	0.1	0.8	-0.2	-0.9	0.4	0.1	-0.4	-0.0	-0.2	0.1	0.0	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.9	-0.1	0.1	0.9	-0.2	-0.0	-0.3	1.0	-0.2	0.2	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.6	0.0	0.8	-0.5	0.1	0.0	0.1	0.0	0.2	0.1	-0.5
Smoking status: Current	0.1	0.1	0.3	-0.3	0.3	-0.5	-0.5	-0.2	-0.5	-0.3	-0.4	0.1	-0.6
Guilty feelings	0.1	0.2	1.3	-0.3	0.7	-0.1	-0.1	-1.2	-0.1	0.4	-0.2	-0.0	0.2
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	-0.4	0.4	-0.2	-0.3	0.1	-0.3	-0.4	-0.4	-0.6	0.4
Supplements: Calcium	0.1	0.2	0.6	0.3	0.3	0.3	0.4	-0.2	0.4	-0.2	0.5	-0.0	0.8
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prospective memory result	0.0	0.1	0.1	-0.3	-0.3	-0.1	-0.0	0.2	-0.0	-0.3	-0.1	-0.3	-0.4
Medication: Ibuprofen	0.0	0.1	0.2	-0.1	0.2	0.1	-0.1	0.1	-0.2	0.3	-0.1	0.4	-0.4

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GGA3

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