Best TWAS P=1.39e-09 · Best GWAS P=6.75e-11 conditioned to 0.00393
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | CTA-85E5.10 | 0.09 | 0.01 | enet | 16 | 0.02 | 2.3e-02 | -4.9 | -5.6 | 2.3e-08 | -0.48 | 0.07 | 0.42 | FALSE |
| 2 | METSIM | Adipose | MTMR3 | 0.08 | 0.08 | bslmm | 479 | 0.06 | 1.0e-09 | -4.9 | -5.2 | 2.5e-07 | -0.50 | 0.98 | 0.02 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | HORMAD2 | 0.06 | 0.04 | enet | 10 | 0.07 | 5.7e-07 | 6.4 | -6.0 | 2.4e-09 | -0.94 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MTMR3 | 0.21 | 0.08 | blup | 72 | 0.16 | 2.5e-15 | 5.1 | -6.1 | 1.4e-09 | -0.78 | 0.01 | 0.99 | TRUE |