[Hub]/) : Traits : Comparative height size at age 10 :

chr22:37,781,874-39,355,109

Best TWAS P=2.56e-11 · Best GWAS P=2.02e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BAIAP2L2 0.11 0.03 lasso 5 0.04 1.8e-04 5.1 -5.6 2.1e-08 -0.75 0.12 0.50 FALSE
2 GTEx Cells EBV-transformed lymphocytes PLA2G6 0.28 0.17 enet 13 0.18 1.3e-06 -3.6 5.2 1.6e-07 0.70 0.06 0.91 FALSE
3 GTEx Cells Transformed fibroblasts PLA2G6 0.23 0.09 lasso 9 0.10 9.9e-08 6.7 6.4 2.1e-10 0.83 0.08 0.92 FALSE
4 GTEx Cells Transformed fibroblasts MAFF 0.08 0.08 lasso 3 0.06 2.2e-05 5.6 -5.4 5.8e-08 -0.71 0.26 0.43 FALSE
5 GTEx Esophagus Mucosa PLA2G6 0.22 0.02 lasso 6 0.04 1.9e-03 6.7 6.2 4.4e-10 0.80 0.02 0.97 FALSE
6 GTEx Nerve Tibial PLA2G6 0.34 0.08 lasso 8 0.11 2.9e-08 -3.6 5.5 3.7e-08 0.74 0.10 0.90 FALSE
7 GTEx Nerve Tibial MAFF 0.14 0.06 lasso 3 0.05 1.2e-04 7.0 -6.7 2.6e-11 -0.99 0.00 0.99 TRUE
8 GTEx Skin Sun Exposed Lower leg BAIAP2L2 0.09 0.09 lasso 4 0.09 5.5e-08 6.2 -6.6 5.7e-11 -0.77 0.05 0.95 FALSE
9 GTEx Thyroid TMEM184B 0.19 0.16 lasso 7 0.18 1.0e-13 3.8 -5.3 9.1e-08 -0.66 0.54 0.46 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2G6 0.05 0.01 blup 76 0.01 7.7e-02 6.5 5.9 4.1e-09 0.85 0.02 0.73 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma PLA2G6 0.03 0.02 lasso 2 0.03 6.5e-04 5.5 5.4 5.1e-08 0.82 0.09 0.16 FALSE