TWAS
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Traits
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Traits
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Comparative height size at age 10
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chr3:71,726,259-73,191,526
Best TWAS P=3.91e-09 · Best GWAS P=2.89e-27 conditioned to 2.92e-21
71.8M
72M
72.2M
72.4M
72.6M
72.8M
73M
73.2M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
RYBP
0.25
0.16
enet
33
0.23
7.8e-75
4.1
-5.9
3.9e-09
-0.31
1.00
0.00
TRUE
3
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
RYBP
0.10
0.00
blup
62
0.04
5.4e-04
-3.0
-5.2
2.5e-07
-0.05
0.06
0.04
FALSE
1
NTR
Blood
RYBP
0.05
0.03
lasso
5
0.04
5.4e-14
-4.3
-5.2
2.6e-07
-0.22
1.00
0.00
FALSE