Best TWAS P=3.91e-09 · Best GWAS P=2.89e-27 conditioned to 2.92e-21
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | RYBP | 0.05 | 0.03 | lasso | 5 | 0.04 | 5.4e-14 | -4.3 | -5.2 | 2.6e-07 | -0.22 | 1.00 | 0.00 | FALSE |
2 | YFS | Blood | RYBP | 0.25 | 0.16 | enet | 33 | 0.23 | 7.8e-75 | 4.1 | -5.9 | 3.9e-09 | -0.31 | 1.00 | 0.00 | TRUE |
3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | RYBP | 0.10 | 0.00 | blup | 62 | 0.04 | 5.4e-04 | -3.0 | -5.2 | 2.5e-07 | -0.05 | 0.06 | 0.04 | FALSE |