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chr3:97,541,855-99,315,838

Best TWAS P=8.14e-19 · Best GWAS P=4.96e-14 conditioned to 0.024

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	DCBLD2	0.16	0.13	lasso	3	0.14	2.4e-11	-6.267	5.9	3.6e-09	0.64	0.92	0.08	FALSE
2	GTEx	Artery Tibial	ST3GAL6	0.14	0.09	enet	21	0.16	3.4e-12	6.558	-6.0	2.5e-09	-0.70	0.53	0.47	FALSE
3	GTEx	Brain Cerebellar Hemisphere	DCBLD2	0.26	0.20	lasso	3	0.14	1.9e-04	-4.695	5.7	1.5e-08	0.59	0.27	0.42	FALSE
4	GTEx	Brain Frontal Cortex BA9	DCBLD2	0.32	0.22	lasso	7	0.22	1.6e-06	-4.695	5.4	5.6e-08	0.59	0.60	0.25	FALSE
5	GTEx	Brain Frontal Cortex BA9	ST3GAL6-AS1	0.52	0.32	enet	29	0.26	1.2e-07	-3.770	5.2	2.2e-07	0.31	0.48	0.36	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	DCBLD2	0.24	0.21	lasso	4	0.19	1.4e-07	-6.089	6.1	9.2e-10	0.69	0.25	0.74	FALSE
7	GTEx	Esophagus Mucosa	DCBLD2	0.11	0.12	lasso	4	0.11	1.5e-07	6.525	6.7	1.8e-11	0.85	0.62	0.38	FALSE
8	GTEx	Esophagus Mucosa	ST3GAL6	0.21	0.14	enet	9	0.09	2.5e-06	-3.770	5.6	2.2e-08	0.45	0.97	0.03	FALSE
9	GTEx	Esophagus Muscularis	DCBLD2	0.21	0.19	lasso	6	0.17	1.6e-10	-4.684	5.4	6.7e-08	0.71	0.79	0.21	FALSE
10	GTEx	Nerve Tibial	DCBLD2	0.14	0.05	lasso	5	0.03	1.7e-03	6.186	7.4	1.4e-13	0.33	0.25	0.13	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	DCBLD2	0.25	0.25	lasso	5	0.24	1.4e-13	6.508	6.6	3.1e-11	0.85	0.57	0.43	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	ST3GAL6	0.15	0.18	lasso	5	0.18	5.1e-10	6.427	6.5	1.1e-10	0.84	0.59	0.41	FALSE
13	GTEx	Skin Sun Exposed Lower leg	DCBLD2	0.17	0.12	lasso	7	0.15	9.2e-13	6.427	6.0	2.0e-09	0.88	0.01	0.99	FALSE
14	GTEx	Skin Sun Exposed Lower leg	ST3GAL6	0.07	0.04	enet	16	0.04	2.0e-04	6.484	7.5	4.2e-14	0.83	0.02	0.97	FALSE
15	GTEx	Thyroid	DCBLD2	0.14	0.12	lasso	5	0.15	1.5e-11	-6.267	7.2	8.5e-13	0.74	0.89	0.11	FALSE
16	GTEx	Thyroid	ST3GAL6	0.07	0.02	enet	12	0.05	6.4e-05	5.222	6.5	8.4e-11	0.58	0.03	0.84	FALSE
17	METSIM	Adipose	CPOX	0.09	0.02	blup	456	0.05	6.4e-08	-0.058	-5.5	4.5e-08	-0.16	0.92	0.06	FALSE
18	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DCBLD2	0.07	0.06	enet	3	0.07	7.6e-04	-5.285	5.4	8.2e-08	0.60	0.12	0.13	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCBLD2	0.09	0.01	enet	16	0.04	9.6e-05	6.567	8.9	8.1e-19	0.66	0.05	0.77	TRUE