Best TWAS P=9.59e-107 · Best GWAS P=3.29e-107 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PCOLCE2 | 0.16 | 0.12 | lasso | 4 | 0.12 | 5.5e-14 | 5.05 | 5.2 | 2.2e-07 | -0.03 | 0.00 | 1.00 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | SPSB4 | 0.03 | 0.01 | bslmm | 414 | 0.01 | 7.3e-03 | 0.85 | -5.3 | 9.4e-08 | -0.28 | 0.16 | 0.09 | FALSE |
| 3 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 21.96 | 21.9 | 9.6e-107 | 0.98 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Colon Transverse | ACPL2 | 0.15 | -0.01 | lasso | 4 | 0.00 | 5.7e-01 | 7.19 | 7.4 | 1.1e-13 | 0.30 | 0.05 | 0.05 | TRUE |
| 5 | GTEx | Muscle Skeletal | ATP1B3 | 0.11 | 0.02 | enet | 24 | 0.03 | 1.1e-03 | -0.73 | -6.2 | 6.5e-10 | -0.23 | 0.15 | 0.04 | FALSE |
| 6 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | 12.74 | 14.9 | 3.4e-50 | 0.59 | 0.23 | 0.62 | FALSE |
| 7 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | 14.03 | 14.1 | 1.9e-45 | 0.62 | 0.07 | 0.92 | FALSE |
| 8 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 21.82 | 19.4 | 1.7e-83 | 0.87 | 0.01 | 0.99 | FALSE |
| 9 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 13.08 | 15.9 | 8.5e-57 | 0.59 | 0.05 | 0.32 | FALSE |