Hub : Genes

PCOLCE2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1570	0.0410	4.1e-07	0.122	0.067	0.098	0.109	0.116	1.4e-14	1.3e-08	5.3e-12	3.6e-13	5.5e-14
2	GTEx	Artery Aorta	0.1620	0.0590	2.3e-03	0.153	NA	0.143	NA	0.145	8.9e-09	NA	2.9e-08	NA	2.3e-08
3	GTEx	Heart Left Ventricle	0.1896	0.0682	1.9e-03	0.001	NA	0.001	NA	0.001	2.9e-01	NA	2.8e-01	NA	2.8e-01
4	GTEx	Muscle Skeletal	0.0452	0.0201	5.3e-03	0.024	NA	0.007	NA	0.009	1.7e-03	NA	5.8e-02	NA	3.6e-02
5	GTEx	Testis	0.3090	0.0760	8.0e-05	0.185	NA	0.163	NA	0.201	1.3e-08	NA	1.1e-07	NA	2.6e-09
6	TCGA	Bladder Urothelial Carcinoma	0.1050	0.0480	2.4e-03	0.028	0.006	0.019	NA	0.027	1.7e-03	9.8e-02	9.0e-03	NA	2.4e-03
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.1010	0.0396	5.4e-06	0.015	0.054	0.050	NA	0.031	7.7e-03	1.0e-06	2.7e-06	NA	1.9e-04
8	TCGA	Brain Lower Grade Glioma	0.1263	0.0336	1.5e-11	0.142	0.107	0.120	NA	0.137	8.1e-16	4.0e-12	1.7e-13	NA	2.3e-15

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.2	0.2	0.8	-0.2	-0.0	0.9	-0.7	0.3	-0.6	0.4	0.0
Bipolar Disorder or Schizophrenia	0.4	1.0	2.6	-1.2	-1.1	-0.5	-0.7	0.8	-1.6	-0.6	-1.1
Depressed Affect (Nagel 2018)	0.8	1.7	3.0	-1.4	-1.4	-1.3	-1.7	0.9	0.8	-1.2	-1.6
Depression (Nagel 2018)	1.8	2.8	6.9	-2.2	-2.0	-1.7	-0.6	0.7	-0.1	-2.6	-1.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.9	0.5	0.7	-0.3	1.7	-0.5	0.8	0.3	0.8
Neuroticism (Nagel 2018)	0.8	1.8	3.9	-1.4	-1.5	-1.0	-2.0	1.0	0.2	-1.4	-1.6
Schizophrenia (2018)	0.7	1.5	2.6	-1.4	-1.3	-1.5	-0.3	0.8	-1.6	-0.9	-1.4
Schizophrenia vs Biploar Disorder	1.1	1.5	2.6	-1.5	-1.3	-1.4	-0.4	0.8	-0.7	-1.6	-1.4
Worry (Nagel 2018)	0.1	0.2	0.9	0.2	-0.1	0.9	-0.9	-0.0	-0.1	0.3	-0.1
Alzheimer’s Disease (in mother)	0.9	1.0	3.4	-1.2	-1.1	1.9	0.5	-1.0	-0.1	-0.3	-0.8
Alzheimer’s Disease (in father)	2.1	2.3	4.9	-1.4	-1.6	0.4	-1.6	2.2	-1.5	-1.3	-1.6
Alzheimer’s Disease (including proxy)	1.7	2.5	5.0	-2.2	-2.2	2.0	-0.2	-0.0	-1.1	-0.7	-2.1
Crohns Disease (2017)	0.0	0.0	0.2	0.2	0.0	-0.2	-0.1	-0.1	0.1	-0.2	0.4
Irritable Bowel Disease (IBD)	0.9	2.2	5.3	2.3	2.0	0.3	-0.2	-0.7	0.4	1.6	2.3
Ulcerative Colitis (UC)	2.8	5.2	13.1	3.6	3.2	0.4	-0.5	-0.8	0.7	2.4	3.3
Major Depression (MDD)	1.6	2.0	4.1	-1.1	-0.9	-0.5	-2.0	1.5	-1.5	-2.0	-0.8
Reaction Time	0.8	1.6	7.7	-0.1	-0.0	2.8	-2.1	0.4	-0.5	0.2	0.0
Verbal and Numeric Reasoning (VNR)	0.4	0.9	4.1	-0.2	0.2	-1.6	2.0	-0.8	0.1	0.4	0.2
Breast Cancer	0.4	0.9	4.0	-0.3	-0.1	-1.2	-0.7	-2.0	0.6	0.7	0.1
Ovarian Cancer	1.5	2.0	4.0	1.3	1.8	-0.2	0.2	-1.7	2.0	0.5	2.0
Prostate Cancer	0.8	1.2	4.8	-0.3	-0.4	2.2	-1.7	-0.5	-0.3	1.0	-0.1
Age at First Birth	0.3	0.5	1.6	0.2	-0.0	-0.1	-1.3	-0.1	0.7	1.2	0.2
Bipolar Disorder (2011)	0.3	0.3	0.8	-0.1	0.5	-0.9	0.4	0.1	-0.2	0.5	0.6
Body Mass Index (BMI) (2010)	1.7	2.4	7.6	-0.1	0.6	-1.7	2.8	-0.5	-1.3	-2.4	0.4
Coronary Artery Disease (CAD)	0.5	0.6	3.2	0.1	-0.1	1.0	0.7	0.2	-1.8	0.3	-0.3
Crohns Disease (2012)	1.0	1.7	3.8	-1.7	-2.0	-0.3	0.5	1.4	-0.7	-1.2	-1.6
Mean Putamen Volume	0.5	0.6	2.2	0.2	0.1	1.0	-1.5	1.0	0.7	0.2	0.2
Fasting Glucose	0.5	0.6	1.7	0.1	-0.2	0.3	-0.3	1.2	-1.2	-1.3	0.2
HbA1C	0.4	0.5	1.0	1.0	0.7	-0.0	-1.0	-0.3	0.7	0.3	0.7
HDL Cholesterol	0.2	0.4	1.8	-0.3	-0.4	1.4	-0.7	0.5	0.2	0.3	-0.4
LDL Cholesterol	2.1	3.4	6.3	-2.0	-2.1	1.7	-0.7	1.1	-2.0	-1.8	-2.5
Lupus	0.3	0.4	1.0	-1.0	-0.6	-0.1	0.2	0.9	-0.5	-0.5	-0.8
Neuroticism (2016)	1.4	2.0	7.0	-1.0	-1.1	-0.1	-1.5	2.6	-1.6	-0.9	-1.1
Primary Biliary Cirrhosis	0.5	0.7	2.4	0.2	0.4	-1.5	1.3	-0.9	0.5	0.4	0.5
Rheumatoid Arthritis	0.2	0.3	1.0	0.6	-0.0	0.6	0.5	-1.0	0.5	-0.4	-0.1
Schizophrenia (2014)	1.0	2.1	2.9	-1.6	-1.5	-1.7	-0.7	1.2	-1.6	-1.4	-1.6
Triglycerides	0.8	1.3	3.1	-1.8	-1.4	-0.0	1.5	0.3	0.9	-0.7	-1.4
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.3	-0.1	-0.3	-0.8	1.0	-0.7	-0.4	-1.5	-0.4
Ulcerative Colitis	0.8	1.2	3.9	1.3	1.2	-0.2	0.1	0.2	-0.9	2.0	1.4
Blood Eosinophil Count	0.4	2.9	10.1	-0.7	-1.2	2.7	-3.2	1.7	-0.4	0.1	-1.1
Blood Platelet Count	1.3	15.4	35.5	-5.3	-5.7	-1.3	-0.7	3.4	-2.1	-2.8	-6.0
Blood Red Count	0.3	3.0	10.4	0.7	0.7	-2.5	-3.2	-1.1	1.3	1.6	0.7
Blood White Count	1.3	9.3	19.8	-3.9	-4.4	2.0	-2.6	1.9	-2.2	-1.0	-4.5
Heel T-Score	0.7	5.2	14.1	0.4	0.8	2.7	3.7	-2.1	-0.4	3.8	1.0
BMI	0.8	4.6	12.7	-2.5	-1.9	-3.6	1.0	1.9	-0.1	-2.7	-1.6
Height	1.7	33.2	61.5	7.8	7.5	0.4	-4.3	-7.7	3.1	2.3	7.4
Waist Hip Ratio (WHR)	0.7	3.0	19.3	-0.0	-0.5	0.7	-4.4	1.8	0.8	0.3	-0.7
Systolic Blood Pressure	1.3	6.3	12.8	-3.4	-3.6	0.8	1.9	1.7	-2.1	-1.2	-3.6
Smoking Status	0.8	1.9	7.3	0.1	-0.3	-1.2	-2.7	1.3	-1.5	-1.5	-0.3
Allergy or Eczema	0.4	1.2	5.8	-0.4	-0.6	2.4	-0.7	0.4	-0.8	1.2	-0.6
Cardiovascular Disease	0.4	1.5	3.7	-1.5	-1.3	1.3	0.8	1.9	-0.8	0.2	-1.1
Hypothyroidism (self reported)	0.2	0.5	3.4	-0.5	-0.1	-0.1	-0.4	0.5	1.8	-0.0	0.3
Respiratory disease	0.0	0.1	0.5	0.0	0.1	0.5	0.1	-0.1	0.0	0.7	0.3
Type 2 Diabetes (T2D) (2018)	0.4	0.8	3.1	-0.3	-0.1	1.8	-0.3	0.3	1.1	1.4	-0.1
Lung FEV1/FVC ratio	1.8	9.3	18.7	-3.5	-2.9	-2.0	4.3	1.7	-3.2	-2.9	-3.2
Lung FVC	0.2	1.1	3.0	-0.7	-1.0	0.8	-0.6	0.9	-1.1	-1.7	-1.0
Neuroticism	0.5	1.1	4.7	-0.6	-0.8	-0.9	-2.2	0.8	-0.1	-1.1	-0.9
Chronotype (morning person)	0.9	2.2	4.5	-1.6	-1.9	-0.9	-0.3	1.8	-0.6	-1.5	-2.1
Hair Pigment	0.1	1.6	12.1	0.3	0.1	0.4	-3.5	0.6	0.5	0.1	0.0
Tanning	0.0	0.2	0.8	0.1	-0.0	-0.5	0.4	0.4	0.1	-0.9	-0.3
Hand grip strength (left)	1.1	2.8	16.8	-0.1	-0.4	0.7	-4.1	0.7	-1.9	-0.6	-0.6
Number of treatments/medications taken	0.5	1.0	2.6	0.1	0.2	1.5	0.1	-1.6	1.4	0.9	0.3
Average weekly spirits intake	0.7	0.8	4.4	0.2	0.1	2.1	0.9	-1.0	0.3	0.6	0.0
Sensitivity / hurt feelings	1.5	2.5	8.9	-1.3	-1.1	-1.7	-3.0	1.3	0.3	-1.4	-1.3
Frequency of depressed mood in last 2 weeks	2.3	3.2	6.2	-2.5	-2.3	-1.3	0.6	1.5	-1.0	-1.7	-2.3
Hearing difficulty/problems: Yes	0.7	1.0	2.1	1.0	1.4	1.1	0.2	0.0	1.2	0.7	1.4
Relative age of first facial hair	0.5	1.1	4.7	-0.9	-1.0	-0.5	0.1	2.2	0.2	-1.0	-1.1
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.5	-1.2	-1.2	-1.2	-0.1	0.6	-0.2	-0.9	-1.1
Ever used hormone-replacement therapy (HRT)	0.3	0.3	1.9	-0.1	0.1	0.4	-1.4	-0.6	0.5	-0.2	0.2
Ever had hysterectomy (womb removed)	2.9	3.2	8.2	2.9	2.7	0.1	-0.6	-0.5	0.8	1.0	2.8
Systolic blood pressure, automated reading	1.6	4.5	7.7	-2.8	-2.6	1.3	2.7	1.8	-1.6	-0.8	-2.6
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.0	0.0	-0.1	0.8	-0.8	-0.1	-0.1	1.4	-0.6
Angina	1.3	1.7	3.9	1.2	1.3	0.2	-0.4	-2.0	1.2	1.4	1.6
Medication for hormone replacement therapy	1.5	1.7	4.0	-1.7	-2.0	-0.4	-1.0	0.8	-0.4	-0.8	-2.0
Vitamin and mineral supplements	0.2	0.2	0.9	-0.6	-0.3	1.0	-0.1	0.5	-0.2	-0.4	-0.1
Supplements: Zinc	0.4	0.4	0.8	0.5	0.6	-0.4	-0.4	-0.8	0.5	0.9	0.6
Medication: Co-codamol	0.2	0.3	0.7	0.8	0.8	-0.2	-0.3	-0.2	-0.4	-0.3	0.7
Medication: Metformin	0.5	0.8	2.7	-0.3	-0.1	0.8	-0.9	-1.6	1.0	0.9	-0.1
Diabetes (father)	3.4	4.2	9.7	-3.1	-3.0	1.4	-1.5	1.2	-0.4	-0.3	-3.0
Diabetes (mother)	0.2	0.3	1.1	0.2	-0.0	-1.0	-0.2	-0.7	0.1	-0.9	0.1
Severe depression (siblings)	1.9	2.1	8.9	-0.8	-0.9	0.3	-3.0	1.5	-1.6	-0.5	-1.0
Pack years adult smoking proportion	0.7	1.0	2.5	0.9	0.8	1.5	-1.6	-1.0	0.1	0.8	0.7
Impedance of leg (right)	1.1	5.3	9.6	-2.9	-2.6	1.5	2.0	3.1	-2.1	-0.2	-2.7
Leg fat-free mass (left)	1.2	6.5	14.1	2.9	2.8	-2.7	-1.6	-3.7	1.8	-0.4	2.9
Trunk fat percentage	0.6	2.6	5.9	-2.1	-1.5	-2.4	0.3	0.4	0.5	-2.4	-1.3
Hand grip strength (right)	0.9	2.3	13.5	-0.1	-0.6	0.6	-3.7	0.8	-1.1	-1.5	-0.7
Townsend deprivation index at recruitment	0.2	0.3	0.5	0.5	0.4	-0.7	0.4	-0.6	-0.4	-0.5	0.6
Current tobacco smoking	0.6	0.9	3.7	0.3	-0.0	-1.0	-0.2	-1.4	-1.9	-0.9	0.1
Average weekly fortified wine intake	0.6	0.7	3.2	0.3	0.3	-0.6	-0.1	-1.1	-1.8	-0.5	0.6
Maternal smoking around birth	0.4	0.6	1.2	-1.0	-1.0	-0.1	-0.8	0.1	0.2	-1.1	-0.9
Fed-up feelings	0.9	1.6	5.2	-1.1	-0.8	-2.3	-0.2	0.7	0.7	-1.9	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	4.6	-0.5	-0.4	-1.9	-0.9	-0.3	1.0	-2.1	-0.3
Relative age voice broke	0.2	0.3	0.6	-0.6	-0.5	-0.1	0.2	0.8	0.4	0.5	-0.6
Taking other prescription medications	0.4	0.7	2.4	-0.1	0.3	1.6	1.1	-0.8	0.9	0.4	0.5
Age when periods started (menarche)	0.3	0.7	2.9	0.1	-0.4	0.2	0.7	0.6	-1.1	-1.7	-0.6
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.1	1.4	1.5	1.1	1.8	-1.0	-0.2	0.4	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.4	-0.8	-0.8	-0.8	1.7	-0.9	-1.9	-0.5	-0.8
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	2.6	1.6	1.3	-0.5	0.8	-0.2	0.8	1.2	1.3
Qualifications: CSEs or equivalent	1.6	2.1	4.2	-2.0	-1.7	-1.2	0.5	1.8	-0.3	-1.3	-1.7
Serious illness, injury or assault to yourself	0.2	0.2	0.8	0.2	0.2	0.6	-0.9	0.1	0.5	0.4	0.0
High blood pressure	0.3	1.0	2.2	-1.5	-1.4	0.9	0.3	-0.2	-1.3	-0.2	-1.0
Hayfever, allergic rhinitis or eczema	0.5	1.2	3.8	-1.0	-1.1	1.9	0.1	0.0	-0.4	1.3	-1.1
Multivitamins +/- minerals	0.1	0.1	0.6	-0.0	-0.1	-0.8	-0.2	-0.2	0.1	-0.1	-0.2
Stomach or abdominal pain in last month	0.6	0.7	1.8	1.0	0.9	0.2	0.5	0.7	-0.2	1.0	1.4
Supplements: Glucosamine	0.3	0.4	1.3	0.6	0.7	0.9	-0.2	0.4	-1.1	-0.3	0.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.0	-0.2	-0.2	-1.7	0.5	1.2	0.4	-0.6	-0.2
Medication: Atenolol	0.3	0.4	1.1	-1.1	-0.9	-0.6	-0.1	-0.1	0.2	-0.0	-0.8
Medication: Levothyroxine sodium	0.5	0.8	2.6	0.6	1.1	-0.1	-0.6	0.3	1.6	-0.1	1.3
Sitting height	1.9	13.8	35.3	4.6	4.8	-1.7	0.2	-5.9	1.6	1.5	4.8
Chronic bronchitis/emphysema (father)	1.6	1.8	8.9	0.8	0.7	3.0	-1.7	0.3	0.3	1.0	0.8
High blood pressure (mother)	0.1	0.2	0.5	0.6	0.5	0.0	-0.7	0.0	0.6	0.2	0.2
Body mass index (BMI)	0.6	2.5	5.3	-1.9	-1.5	-2.3	0.6	1.0	0.2	-2.3	-1.3
Impedance of leg (left)	0.8	4.0	8.1	-2.6	-2.3	1.3	1.1	2.9	-1.8	0.2	-2.4
Leg predicted mass (left)	1.3	6.7	14.4	3.0	2.8	-2.7	-1.7	-3.8	1.8	-0.4	3.0
Trunk fat mass	0.5	2.0	7.1	-1.4	-0.8	-2.7	-0.1	-0.4	0.9	-2.3	-0.5
Waist circumference	0.4	1.3	2.8	-1.3	-1.1	-1.5	-0.9	0.1	1.0	-1.7	-0.8
Number of incorrect matches in round	0.4	0.7	2.0	-0.2	-0.7	1.4	-0.8	0.7	-0.3	1.1	-0.9
Past tobacco smoking	1.9	3.5	15.3	0.8	1.2	1.3	3.9	-1.9	0.9	1.8	1.1
Alcohol usually taken with meals	0.6	1.0	3.9	0.1	-0.0	1.0	0.9	-0.1	1.5	2.0	0.2
Nervous feelings	0.4	0.7	1.2	0.7	0.9	0.8	0.9	-0.4	-0.7	1.1	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.7	-0.9	-1.3	-0.5	0.5	1.2	-0.6	-0.7	-1.2
Hearing difficulty/problems with background noise	2.0	3.2	5.8	2.3	2.3	0.4	-0.9	-0.9	2.1	1.8	2.4
Hair/balding pattern: Pattern 2	2.7	3.4	7.0	-1.6	-1.6	-2.6	0.1	2.3	-1.1	-2.6	-1.4
Had menopause	0.9	1.2	3.5	1.0	1.1	1.9	-0.8	-0.7	0.6	0.7	1.3
Had other major operations	2.5	3.1	5.4	1.7	1.7	2.3	0.7	-2.0	0.6	1.9	2.3
Forced vital capacity (FVC)	0.5	1.8	4.8	2.2	1.7	-0.4	-1.5	-1.0	-0.4	-0.4	1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	4.1	0.1	0.4	-0.8	2.0	-0.5	-0.9	0.3	0.5
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	3.1	-1.4	-1.1	0.7	-1.8	0.0	0.3	-1.1	-1.0
Qualifications: None of the above	0.1	0.3	1.4	-0.1	-0.2	0.0	0.7	-0.0	-1.2	-0.6	-0.2
Financial difficulties in last 2 years	0.7	1.0	2.5	-1.4	-1.5	-0.3	0.5	0.7	0.5	-0.2	-1.6
Mouth/teeth dental problems	0.2	0.3	0.7	-0.5	-0.9	-0.5	-0.3	-0.7	0.7	0.3	-0.7
Heart attack	1.2	1.5	3.0	1.7	1.6	1.5	-0.6	-0.6	0.6	0.8	1.5
Allergy	0.3	0.8	3.1	0.7	0.6	-1.7	-0.6	-0.1	0.2	-1.2	0.6
Pain all over the body in last month	0.4	0.5	2.3	0.1	0.3	-0.1	-0.2	-0.7	1.5	0.7	0.5
Diabetes (self-reported)	1.0	1.6	6.8	-0.4	-0.2	2.6	-0.4	-0.7	1.5	1.6	-0.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.7	0.6	0.4	-0.1	1.0	-1.0	-1.6	0.1	0.4
Medication: Ramipril	0.6	0.8	2.3	-0.0	0.4	1.2	-0.7	-1.5	0.6	1.3	0.3
Medication: Simvastatin	3.0	4.4	11.1	-3.3	-3.1	1.7	-0.3	1.2	0.2	-0.7	-3.0
Fluid intelligence score	0.4	0.8	1.7	1.0	0.9	-0.9	0.9	-0.3	1.3	0.9	0.9
Illnesses of siblings	0.1	0.1	0.3	0.2	0.2	0.1	-0.4	0.5	0.5	-0.2	0.3
Neuroticism score	0.5	1.0	2.2	-0.9	-1.0	-1.1	-1.5	0.9	0.1	-0.8	-1.1
Weight	0.4	1.7	5.8	0.4	0.7	-2.4	-0.6	-1.6	1.3	-1.4	0.9
Impedance of arm (right)	0.1	0.3	0.8	0.3	0.3	0.8	-0.8	-0.2	0.5	0.9	0.4
Arm fat percentage (right)	0.6	2.5	5.2	-2.1	-1.6	-2.3	0.0	1.2	0.8	-2.0	-1.3
Trunk fat-free mass	0.9	5.0	10.5	3.0	2.7	-1.6	-1.7	-3.2	0.8	0.2	2.7
Hip circumference	0.3	1.2	4.1	-0.5	-0.2	-2.0	1.3	-1.1	1.0	-1.2	-0.1
Time employed in main current job	0.7	0.8	3.0	-1.0	-0.6	-1.7	0.9	-0.2	0.1	-1.1	-0.2
Alcohol intake versus 10 years previously	1.6	2.5	7.1	-1.7	-1.5	2.7	1.3	1.1	-1.5	0.2	-1.5
Father’s age at death	2.8	3.8	6.4	-2.1	-2.2	2.5	1.9	2.1	-0.5	0.1	-2.5
Worrier / anxious feelings	0.2	0.4	1.9	0.2	0.2	-0.1	-1.4	-1.0	0.4	-0.6	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.9	-0.7	-0.7	-0.1	0.4	-1.1	-1.4	-0.3	-0.6
Falls in the last year	0.3	0.4	1.7	0.2	0.1	0.5	-0.6	-0.4	1.3	0.6	-0.1
Hair/balding pattern: Pattern 3	1.0	1.5	3.0	1.7	1.7	1.3	0.2	-1.3	-0.3	0.6	1.4
Number of live births	0.9	1.2	7.0	1.0	0.8	-2.6	-0.4	-0.0	0.1	-0.3	0.9
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.2	0.7	0.3	-0.6	-0.8	0.0	-1.8	-1.6	0.2
Pulse rate	0.8	1.4	4.7	0.7	0.5	1.8	1.2	0.9	-2.2	0.1	0.5
Happiness	1.0	1.2	6.8	-0.1	-0.5	0.3	-2.6	-0.4	1.0	0.8	-0.4
Noisy workplace	0.8	1.0	1.6	1.1	1.3	1.2	0.7	-1.1	-0.4	0.7	1.3
Qualifications: A levels/AS levels or equivalent	0.3	0.7	3.0	0.1	0.0	-0.8	0.1	-1.7	-1.4	-0.5	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.4	-1.0	-1.0	0.5	-1.5	1.2	0.8	-0.0	-0.8
Mouth/teeth dental problems: Dentures	1.2	2.0	4.7	2.0	2.2	0.4	-0.9	-0.5	1.1	0.5	2.2
Asthma	0.2	0.4	1.1	-1.1	-0.6	0.5	-0.1	-0.9	-0.5	0.2	-0.4
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	2.5	1.4	1.2	0.1	0.7	-1.3	1.6	0.7	1.0
Medication: Cholesterol lowering	2.1	3.2	8.3	-2.9	-2.3	1.8	-1.2	0.6	1.0	-0.6	-2.4
Depression (self-reported)	1.5	1.8	4.2	-1.3	-1.5	-0.8	-2.0	0.3	-0.7	-1.4	-1.7
Medication: Lansoprazole	1.1	1.3	4.0	-1.0	-0.9	-0.0	0.9	0.4	-2.0	-1.6	-0.8
Prospective memory result	0.8	1.0	3.9	-0.4	-0.7	-0.7	-1.5	2.0	-0.1	0.3	-0.7
Lung cancer (father)	0.6	0.7	2.2	0.7	0.8	-0.7	-1.5	-0.5	0.6	-0.1	1.0
Illnesses of mother	0.7	0.9	2.6	-1.2	-1.1	-1.6	-0.1	0.6	0.8	-0.5	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	4.6	1.0	0.5	-0.3	-1.0	0.6	-1.5	-2.1	0.3
Pulse wave Arterial Stiffness index	1.2	1.4	3.9	1.4	1.3	0.9	-1.1	-2.0	0.1	0.1	1.3
Impedance of arm (left)	0.0	0.2	0.6	0.2	0.3	-0.3	-0.8	-0.4	0.6	-0.0	0.4
Arm fat mass (right)	0.4	1.8	7.7	-1.2	-0.8	-2.8	-0.3	0.1	0.8	-2.0	-0.5
Trunk predicted mass	0.9	4.9	10.0	3.0	2.7	-1.5	-1.7	-3.2	0.8	0.3	2.7
Standing height	1.4	14.4	31.5	4.8	4.8	-1.1	-2.6	-5.6	2.2	1.5	4.8
Length of working week for main job	0.6	0.6	1.3	-0.6	-0.8	0.2	0.1	0.9	-1.1	-1.1	-0.7
Exposure to tobacco smoke at home	0.5	0.5	3.0	0.2	0.4	0.0	1.7	-0.7	0.4	0.1	0.6
Breastfed as a baby	0.8	0.9	4.7	-0.5	-0.5	2.2	-0.4	0.3	-0.1	1.3	-0.7
Tense / ‘highly strung’	0.3	0.6	3.2	-0.1	-0.5	-0.3	-0.6	1.8	-0.2	-0.6	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.0	-0.4	-0.5	-0.5	-1.1	-0.0	-0.3	-1.4	-0.3
Hair/balding pattern: Pattern 4	0.9	2.2	10.2	0.0	0.2	3.2	0.7	-0.8	1.7	1.9	0.0
Birth weight of first child	1.1	1.9	8.0	0.6	0.3	-0.3	-2.8	-0.4	2.5	-0.0	0.4
Peak expiratory flow (PEF)	0.9	2.2	8.0	0.2	-0.1	-1.5	-0.7	0.3	-2.8	-2.5	-0.2
Pulse wave reflection index	1.3	1.6	5.3	0.9	0.9	0.4	-1.2	-2.3	1.2	1.4	1.0
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.1	-0.9	-1.1	0.5	-1.3	1.4	-0.9	-0.8	-1.2
Loud music exposure frequency	1.2	1.4	4.8	-0.7	-0.7	-0.5	-2.2	0.8	-1.3	-1.5	-0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.1	-0.2	-0.2	-0.4	0.5	-0.7	0.7	-1.0	-0.3
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.4	-1.4	-1.3	0.1	1.5	0.7	-1.6	-1.0	-1.4
Blood clot in the leg (DVT)	0.4	0.5	2.5	0.6	0.6	1.6	-0.4	-0.1	0.5	-0.1	0.3
Medication: Paracetamol	0.3	0.5	3.1	-0.2	-0.4	-0.2	-0.8	0.3	1.8	0.2	-0.4
Headache pain in last month	1.0	1.7	3.9	-2.0	-1.9	0.5	0.4	0.7	-1.3	-0.7	-1.7
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	4.6	2.1	2.0	-1.4	1.2	-0.3	-0.4	1.0	2.1
Glaucoma (self-reported)	0.9	1.1	3.7	-0.1	-0.4	0.2	0.4	-1.4	1.6	1.9	-0.3
Gout (self-reported)	2.5	3.4	12.6	-2.0	-1.7	-0.1	1.8	3.5	-0.1	-0.7	-1.9
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.6	0.1	0.4	0.8	-0.0	0.4	1.3	0.3	0.7
Medication: Amlodipine	0.9	1.3	2.6	-0.9	-1.4	-0.4	-1.6	0.7	-1.0	-1.3	-1.4
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.9	0.1	0.3	-0.7	0.9	-0.1	0.1	-1.4	0.6
Birth weight	1.4	3.1	10.6	-0.1	-0.3	-2.6	-3.2	0.6	0.4	-2.6	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.2	-0.3	-0.4	0.6	0.1	1.1	-0.4	-0.1	-0.5
High blood pressure (siblings)	0.5	0.7	2.2	-0.6	-0.8	-0.4	0.4	-0.1	-1.5	-1.2	-1.0
Forced vital capacity (FVC), Best measure	0.5	1.9	4.9	2.2	1.7	-0.1	-1.7	-0.6	-0.4	-1.1	1.6
Body fat percentage	0.8	3.1	6.6	-2.6	-1.9	-2.1	0.6	1.1	0.4	-2.3	-1.7
Leg fat percentage (right)	1.3	4.6	9.9	-3.1	-2.5	-1.2	1.9	2.2	-0.3	-2.2	-2.4
Arm fat-free mass (right)	0.6	2.8	6.1	1.9	1.9	-2.1	-1.1	-2.5	0.1	-0.5	1.9
Exposure to tobacco smoke outside home	0.1	0.2	0.5	0.4	0.6	0.4	-0.4	0.4	-0.1	0.0	0.7
Comparative body size at age 10	0.5	1.4	4.3	-0.4	-0.5	-1.8	-1.7	0.5	-0.3	-2.1	-0.5
Number of full brothers	0.6	0.7	3.5	0.7	0.5	-1.9	-0.3	-1.1	-0.0	0.0	0.3
Worry too long after embarrassment	0.4	0.7	3.4	-0.2	-0.4	-0.9	-1.8	-0.5	0.2	-0.7	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	3.4	-1.1	-0.9	-1.0	-0.5	0.9	-0.2	-1.9	-0.9
Wheeze or whistling in the chest in last year	0.2	0.3	0.8	0.2	0.6	-0.1	0.5	-0.9	0.5	-0.1	0.7
Number of children fathered	0.8	0.9	1.7	1.3	1.0	-0.1	0.4	-0.9	1.2	1.1	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.3	-0.7	-0.7	-0.6	-1.1	-0.2	-0.1	0.5	-0.4
Age at first live birth	0.3	0.5	1.2	0.7	0.5	1.0	-1.1	-0.0	0.1	0.8	0.6
Pulse wave peak to peak time	1.0	1.1	2.8	-1.0	-1.0	-1.3	1.1	1.7	0.0	-0.2	-1.0
Health satisfaction	1.1	1.4	3.3	-1.6	-1.8	-0.2	-0.3	1.1	-0.8	-0.9	-1.5
Shortness of breath walking on level ground	1.0	1.2	2.5	1.1	1.1	0.8	-1.5	-1.6	0.6	0.2	1.2
Qualifications: College or University degree	0.6	2.0	4.7	2.2	1.6	-0.9	-1.8	-0.4	-0.3	1.0	1.8
Eye problems/disorders: None of the above	1.0	1.1	2.4	-1.3	-0.9	0.3	1.6	0.7	-0.6	-1.6	-0.8
Mouth/teeth dental problems: Loose teeth	1.4	1.6	4.9	-1.4	-1.2	-0.1	0.5	2.2	-1.3	-0.9	-1.4
Emphysema/chronic bronchitis	1.0	1.1	2.5	1.5	1.6	-1.3	0.1	0.5	0.4	0.0	1.5
Medication for pain relief, constipation, heartburn	1.0	1.6	4.6	-1.2	-1.2	-0.5	0.6	1.7	-2.1	-0.8	-1.2
Neck or shoulder pain in last month	0.4	0.6	2.3	0.6	0.5	-0.1	1.5	1.0	0.5	-0.2	0.5
Medication: Blood pressure	0.8	1.4	2.6	-1.5	-1.6	-0.3	-1.0	-0.4	-0.4	-1.6	-1.6
Angina (self-reported)	0.9	1.2	3.3	0.9	1.0	0.2	-0.4	-1.8	0.8	1.3	1.3
Migraine (self-reported)	0.3	0.4	1.3	0.5	0.4	-0.1	-0.7	-0.1	0.9	1.2	0.3
Medication: Ibuprofen	1.6	1.9	4.2	1.8	1.4	1.2	0.6	-0.9	2.0	1.2	1.3
Medication: Allopurinol	0.7	1.0	3.5	0.7	0.9	0.4	0.7	1.9	1.0	0.8	0.8
Medication: Omeprazole	1.2	1.4	3.1	0.9	1.2	1.8	0.2	-1.2	0.3	1.4	1.5
Medication: Seretide 50 evohaler	0.7	0.8	5.2	-0.6	-0.2	-0.1	0.4	-2.3	0.9	0.4	-0.0
Mean time to correctly identify matches	1.5	2.9	17.1	0.6	0.9	4.1	-1.5	-0.2	0.3	1.1	1.0
Heart disease (mother)	0.2	0.2	0.8	0.2	0.4	0.7	-0.4	0.0	-0.9	-0.3	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.7	0.2	0.1	0.2	-0.9	0.1	0.3	0.5	0.2
Whole body fat mass	0.5	2.0	6.2	-1.6	-1.1	-2.5	0.1	-0.1	0.8	-2.2	-0.8
Leg fat mass (right)	0.6	2.2	5.0	-1.9	-1.3	-2.2	1.1	0.9	0.5	-2.1	-1.0
Arm predicted mass (right)	0.6	3.1	6.6	2.0	1.9	-2.2	-1.1	-2.6	0.0	-0.6	2.0
Pulse rate, automated reading	1.1	3.4	4.5	-1.8	-2.1	2.1	1.5	2.1	-1.8	-1.2	-2.0
Alcohol intake frequency.	1.5	3.4	5.8	-2.4	-2.0	1.5	2.2	1.5	-1.3	-1.4	-2.1
Comparative height size at age 10	2.6	14.2	26.8	5.2	5.1	-1.9	-2.5	-4.5	1.4	1.9	5.1
Number of full sisters	0.7	0.8	3.2	-0.3	-0.5	-0.7	0.2	1.2	-1.8	-0.8	-0.5
Suffer from ‘nerves’	0.6	0.9	2.3	-0.5	-0.9	0.9	-1.1	1.5	-0.6	0.5	-1.0
Overall health rating	0.5	1.1	3.1	-1.4	-1.3	0.2	1.0	0.3	-1.8	0.1	-1.1
Chest pain or discomfort	0.5	0.8	3.3	-0.0	0.2	1.1	0.2	-0.9	-1.8	0.9	0.5
Had major operations	0.3	0.3	1.2	0.2	0.2	-1.1	-0.9	-0.1	0.4	-0.3	0.3
Age at last live birth	0.5	0.7	1.5	1.2	1.2	-0.1	-0.4	-0.6	0.2	0.8	1.2
Family relationship satisfaction	1.2	1.5	9.4	-0.4	-0.6	-0.1	-3.1	0.3	1.2	0.5	-0.4
Leg pain on walking	0.5	0.6	1.4	-0.7	-0.9	0.2	-0.7	-1.2	-0.4	-0.4	-1.1
Qualifications: NVQ or HND or HNC or equivalent	2.0	2.4	3.5	-1.9	-1.5	-1.1	1.1	1.8	-1.4	-1.9	-1.5
Commuting to job workplace: Car/motor vehicle	1.0	1.1	2.9	-0.7	-0.8	-1.0	-1.7	0.7	-1.1	-1.2	-0.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.4	0.7	1.1	-0.1	0.6	-0.1	-0.1	-0.9	1.2
Medication: Aspirin	1.4	1.9	7.7	0.7	0.9	0.7	-1.4	-1.2	2.8	1.1	0.9
Supplements: Vitamin C	0.2	0.3	0.8	0.4	0.3	-0.6	-0.2	0.3	0.7	0.9	0.1
Knee pain experienced in last month	0.7	1.2	4.6	-0.5	-0.5	0.8	1.4	2.1	0.1	-1.1	-0.5
Hypertension (Self-reported)	0.3	0.8	2.1	-1.0	-0.9	1.4	-0.1	-0.2	-1.2	0.7	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.8	4.5	9.0	-2.5	-2.5	0.3	0.1	1.1	-3.0	-2.7	-2.4
Illnesses of father: Heart disease	0.6	0.9	2.2	-0.7	-0.6	1.4	1.5	-0.6	-0.4	-1.0	-0.7
Illnesses of siblings: Diabetes	0.7	0.8	2.4	-0.5	-0.5	1.3	-1.1	1.6	-0.9	0.1	-0.4
Smoking status: Previous	2.0	3.0	9.2	-0.8	-1.1	-0.6	-3.0	2.9	-0.1	-1.7	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	4.7	0.9	1.1	-1.5	-2.2	-1.0	0.8	-0.6	0.6
Whole body fat-free mass	1.0	5.9	13.2	3.1	2.9	-2.0	-1.6	-3.6	1.0	0.0	3.0
Leg fat-free mass (right)	1.5	7.9	16.9	3.3	3.1	-2.7	-2.2	-4.1	1.9	-0.0	3.2
Arm fat percentage (left)	0.8	3.2	7.4	-2.1	-1.7	-2.7	-0.1	1.2	0.9	-2.5	-1.4
Average weekly red wine intake	0.6	0.9	4.5	-0.2	-0.4	0.6	-1.4	0.5	0.0	2.1	-0.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.0	0.7	0.7	-0.7	-0.1	-1.4	-0.9	0.3	0.7
Mood swings	1.5	2.7	4.5	-2.1	-2.0	-0.8	-1.2	2.1	0.1	-1.5	-2.1
Loneliness, isolation	0.4	0.6	2.3	-0.0	-0.2	-0.9	-1.0	0.3	0.0	-1.5	-0.5
Long-standing illness, disability or infirmity	0.4	0.7	3.5	-0.6	-0.4	-0.4	1.9	0.2	-0.0	-1.1	-0.3
Ever had bowel cancer screening	0.7	0.8	2.4	0.3	-0.0	0.9	-1.5	1.4	0.8	-0.7	-0.1
Diabetes diagnosed by doctor	0.7	1.2	3.8	-0.0	0.2	2.0	-0.9	-1.0	1.4	1.3	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.3	-1.1	-0.8	-0.2	1.5	-0.1	-0.6	-1.0	-0.8
Friendships satisfaction	0.6	0.8	2.5	-0.4	-0.8	0.6	-1.6	0.4	0.7	1.2	-0.8
Qualifications: nursing, teaching	0.3	0.5	1.5	0.6	0.7	-0.5	-1.2	-0.4	0.6	-0.3	0.7
Commuting to job workplace: Walk	1.5	1.6	5.1	0.7	0.5	-0.2	1.2	-1.5	1.8	2.3	0.5
Eye problems/disorders: Cataract	0.7	0.8	2.5	0.5	0.2	-1.4	-1.6	-1.1	0.1	0.5	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.5	-0.7	-0.6	-0.4	0.0	1.2	0.5	-0.2	-0.8
Medication for cholesterol	0.5	0.7	1.8	1.3	1.3	-0.0	-0.2	-0.1	1.0	0.0	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.2	-0.5	-0.8	-1.4	-0.2	0.4	0.1	-1.8	-0.7
Back pain experienced in last month	0.2	0.3	1.0	0.4	0.2	0.6	-0.2	1.0	-0.1	-0.9	-0.1
Mineral and other dietary supplements	0.3	0.3	0.9	-0.1	-0.5	-1.0	0.8	-0.4	0.5	-0.8	-0.1
Breast cancer (self-reported)	0.3	0.3	0.8	0.8	0.9	0.4	0.3	-0.2	0.3	0.3	0.8
Asthma (self-reported)	0.2	0.5	1.5	-1.2	-0.8	0.5	-0.1	-0.9	-0.4	0.2	-0.6
Osteoporosis (self-reported)	0.8	0.9	4.3	1.1	0.8	0.6	-2.1	-0.5	0.6	-0.2	0.6
Osteoarthritis (self-reported)	0.4	0.5	2.0	0.6	0.6	-0.1	0.6	-0.2	-0.4	-1.4	0.8
Medication: Aspirin	1.4	1.8	6.5	0.8	0.8	1.0	-1.5	-1.3	2.5	1.2	0.8
Medication: Gliclazide	0.6	0.7	1.5	-0.8	-0.5	1.1	1.2	-1.2	-0.3	0.5	-0.6
Illnesses of father: None of the above (group 1)	2.4	2.9	7.3	1.9	1.8	-2.7	0.8	-1.9	1.2	0.6	1.8
Smoking status: Current	0.7	1.1	4.3	0.2	-0.1	-1.3	-0.2	-1.5	-2.1	-0.8	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	4.4	-1.1	-1.2	1.9	1.5	2.1	-2.0	-1.3	-1.5
Whole body water mass	1.0	5.9	13.3	3.1	2.9	-1.9	-1.7	-3.6	0.9	0.1	3.0
Leg predicted mass (right)	1.4	7.5	16.4	3.1	2.9	-2.8	-2.3	-4.0	1.8	-0.2	3.1
Arm fat mass (left)	0.5	2.2	8.0	-1.4	-1.0	-2.8	-0.1	0.2	0.6	-2.4	-0.7
Number of self-reported non-cancer illnesses	0.5	0.9	1.5	-1.2	-1.1	1.2	0.5	0.9	-0.5	-0.9	-0.9
Average weekly champagne plus white wine intake	0.5	0.8	3.8	0.3	-0.1	-0.4	-0.8	-1.9	1.0	0.6	-0.2
Miserableness	0.7	1.2	2.8	-1.1	-0.8	-1.4	-0.8	1.2	1.7	-0.6	-0.8
Guilty feelings	0.4	0.6	3.5	0.2	0.3	-1.9	-0.5	0.2	0.7	-0.6	0.2
Wears glasses or contact lenses	2.9	3.3	7.3	-2.7	-2.3	0.9	1.7	1.9	-0.6	-1.4	-2.2
Ever taken oral contraceptive pill	2.4	2.7	5.8	-2.3	-1.9	-1.1	0.8	2.4	-0.7	-0.8	-2.1
Hearing aid user	0.7	0.8	3.1	-0.2	-0.4	1.0	-0.8	1.8	0.7	0.9	-0.5
Mother’s age at death	1.7	2.1	4.3	2.1	1.5	1.9	0.0	-1.2	0.1	1.7	1.5
Financial situation satisfaction	0.1	0.1	0.5	0.1	-0.0	-0.0	0.2	-0.4	0.7	-0.0	0.2
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.5	0.6	0.3	-1.2	0.1	0.4	0.6	-0.9	0.4
Commuting to job workplace: Public transport	0.3	0.4	2.1	0.3	0.3	0.7	1.4	-0.1	0.3	-0.4	0.2
Eye problems/disorders: Glaucoma	1.9	2.2	6.5	1.4	1.2	0.7	-0.3	-1.2	2.1	2.5	1.2
Medication: Blood pressure	0.5	0.9	2.5	0.2	0.3	0.7	-0.0	-1.6	-1.2	1.5	0.6
Pain type(s) experienced in last month: Hip pain	1.1	1.3	5.3	0.9	1.1	0.0	0.6	-0.7	2.3	1.1	1.1
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.0	0.8	1.2	0.8	-0.3	-1.2	-0.1	1.4	1.1
High cholesterol (Self-reported)	2.5	4.4	12.4	-3.5	-2.9	2.2	0.4	1.2	-0.6	-0.7	-2.7
Medication: Bendroflumethiazide	0.2	0.4	1.5	-0.8	-0.4	-0.3	-0.5	-1.2	0.0	0.5	-0.2
Medication: Paracetamol	0.7	1.0	5.1	0.4	-0.1	0.5	-0.9	0.1	2.3	1.3	0.1
Medication: Lisinopril	0.6	0.8	4.9	-0.1	-0.0	1.1	-2.2	0.3	-0.7	-0.1	-0.0
Medication: Atorvastatin	0.3	0.3	1.3	-0.1	-0.0	1.1	-0.0	-0.9	-0.1	0.8	0.1
Illnesses of father: High blood pressure	1.1	1.3	2.9	-0.8	-1.0	-1.6	-0.5	1.4	1.7	-0.8	-0.9
Alcohol drinker status: Never	0.8	1.0	5.3	-0.3	-0.3	-1.4	2.3	0.4	0.0	0.1	-0.4
Ever smoked	1.4	2.4	14.4	0.1	-0.4	-1.5	-3.8	0.6	-0.3	-1.4	-0.3
Basal metabolic rate	0.8	4.4	10.2	2.3	2.3	-2.4	-1.5	-3.2	1.0	-0.4	2.4
Leg fat percentage (left)	1.0	3.5	8.1	-2.8	-2.2	-1.5	1.3	1.8	0.0	-1.8	-2.1
Arm fat-free mass (left)	0.5	2.4	5.8	1.9	1.9	-1.2	-1.1	-2.4	-0.0	-0.1	1.9
Number of operations (self-reported)	0.7	1.0	2.6	1.2	1.1	-0.3	-1.1	-0.9	0.7	0.6	1.6
Average weekly beer plus cider intake	0.6	0.9	2.4	0.1	-0.0	-0.4	-1.6	1.4	-0.9	-1.4	-0.1
Irritability	0.5	0.9	3.9	-0.8	-0.8	-0.3	-2.0	0.5	-0.7	-0.9	-0.6
Risk taking	0.5	0.7	1.7	0.7	0.7	-1.1	-1.3	0.0	-0.1	-1.3	0.7
Ever had prostate specific antigen (PSA) test	2.1	2.4	5.1	-2.1	-2.3	-0.0	-0.2	1.8	0.8	-1.3	-2.1
Fractured/broken bones in last 5 years	1.3	1.7	7.3	0.2	0.3	2.7	-1.2	0.0	2.1	-0.1	0.3
Age started oral contraceptive pill	1.0	1.2	2.6	0.8	1.0	0.5	-0.4	-1.5	1.4	1.6	1.1
Diastolic blood pressure, automated reading	1.3	4.1	8.7	1.7	2.1	2.9	1.2	-1.3	1.5	2.5	2.3
Ever depressed for a whole week	0.5	0.6	2.1	-0.1	0.3	1.5	-0.7	-1.0	0.7	0.5	0.4
Unable to work because of sickness or disability	1.0	1.2	2.6	1.2	1.5	0.8	-0.2	0.1	1.6	1.0	1.5
Commuting to job workplace: Cycle	0.5	0.6	3.1	-0.1	0.0	-0.1	0.2	-1.8	-0.8	1.1	0.3
Myopia	6.3	9.2	20.5	-4.5	-4.2	-0.7	1.3	1.2	-1.6	-3.5	-4.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.2	0.3	0.2	-1.1	0.0	0.5	0.1	-0.7	-0.1
Cholesterol lowering medication	0.5	0.7	1.6	-1.3	-1.1	0.6	0.8	0.2	-0.9	0.4	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	3.8	1.1	1.6	1.7	0.7	-1.4	0.8	1.4	1.9
Pain experienced in last month	1.1	1.9	3.6	-1.9	-1.8	-0.9	-1.5	-0.9	-0.7	-1.0	-1.8
Supplements: Calcium	0.6	0.7	3.9	0.2	0.2	-0.3	-2.0	0.4	0.9	-0.3	0.1
Basal cell carcinoma (self-reported)	1.1	1.3	3.8	-1.3	-1.4	-0.6	-0.6	2.0	-0.6	-0.5	-1.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	2.6	1.6	1.5	1.5	-0.7	-0.5	0.5	0.8	1.4
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.0	0.2	0.2	1.4	-0.9	-0.1	0.3	-0.5	-0.0
Heart disease (siblings)	0.3	0.4	1.9	-0.3	-0.4	-1.4	-0.1	-0.1	1.1	-0.0	-0.2
Alcohol drinker status: Previous	1.5	1.7	3.3	-1.4	-1.2	-0.2	0.9	1.7	-1.1	-1.8	-1.3
Pack years of smoking	0.7	1.0	2.8	0.9	0.8	1.7	-1.3	-0.8	0.4	0.9	0.7
Impedance of whole body	0.1	0.6	1.2	-1.1	-0.8	0.6	0.3	1.0	-0.5	0.2	-0.9
Leg fat mass (left)	0.5	1.9	5.6	-1.7	-1.1	-2.4	0.7	0.6	0.7	-1.9	-0.9
Arm predicted mass (left)	0.5	2.5	6.5	1.9	1.9	-1.3	-0.9	-2.5	0.0	-0.1	1.9