Best TWAS P=1.93e-12 · Best GWAS P=2.66e-16 conditioned to 1.77e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NRG2 | 0.04 | 0.01 | lasso | 5 | 0.01 | 1.0e-02 | 3.7 | -5.3 | 1.0e-07 | -0.44 | 0.03 | 0.80 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | DNAJC18 | 0.26 | 0.09 | lasso | 2 | 0.12 | 9.7e-05 | 3.7 | 5.5 | 4.0e-08 | 0.77 | 0.03 | 0.87 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | DNAJC18 | 0.17 | 0.01 | lasso | 10 | 0.04 | 2.0e-02 | 4.0 | 5.7 | 9.8e-09 | 0.77 | 0.07 | 0.65 | FALSE |
| 4 | GTEx | Esophagus Mucosa | TMEM173 | 0.10 | 0.03 | enet | 20 | 0.10 | 1.8e-07 | 7.1 | -5.4 | 5.8e-08 | -0.39 | 0.16 | 0.24 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | UBE2D2 | 0.05 | 0.02 | enet | 6 | 0.03 | 4.4e-04 | 5.1 | 7.0 | 1.9e-12 | 0.91 | 0.01 | 0.97 | TRUE |