TWAS hub - TMEM173

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.3530	0.0860	5.9e-05	0.157	NA	0.152	NA	0.150	5.4e-09	NA	9.8e-09	NA	1.2e-08
2	GTEx	Artery Tibial	0.2386	0.0664	2.1e-05	0.143	NA	0.121	NA	0.134	2.7e-11	NA	9.9e-10	NA	1.2e-10
3	GTEx	Cells Transformed fibroblasts	0.1900	0.0560	8.9e-06	0.172	NA	0.103	NA	0.166	6.8e-13	NA	3.9e-08	NA	1.7e-12
4	GTEx	Esophagus Mucosa	0.0960	0.0410	6.9e-04	0.027	NA	0.105	NA	0.072	6.2e-03	NA	1.8e-07	NA	1.5e-05
5	GTEx	Esophagus Muscularis	0.2350	0.0880	1.8e-04	0.002	NA	0.052	NA	0.060	2.2e-01	NA	4.3e-04	NA	1.5e-04
6	GTEx	Thyroid	0.0850	0.0370	6.5e-03	0.100	NA	0.073	NA	0.091	4.5e-08	NA	3.1e-06	NA	1.8e-07
7	YFS	Blood	0.0366	0.0134	4.6e-05	0.010	0.012	0.031	0.022	0.022	2.9e-04	7.0e-05	2.0e-10	5.2e-08	9.0e-08
8	TCGA	Breast Invasive Carcinoma	0.0247	0.0162	8.7e-07	0.030	0.031	0.025	NA	0.029	8.2e-07	4.6e-07	5.0e-06	NA	9.0e-07
9	TCGA	Glioblastoma Multiforme	0.1260	0.1000	3.4e-03	0.124	0.070	0.083	NA	0.118	1.3e-04	3.6e-03	1.7e-03	NA	2.0e-04
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0242	0.0239	7.9e-03	0.023	0.018	0.017	NA	0.022	1.1e-03	3.7e-03	4.5e-03	NA	1.5e-03
11	TCGA	Lung Squamous Cell Carcinoma	0.0291	0.0223	8.0e-03	-0.001	0.013	0.009	NA	0.004	5.3e-01	1.0e-02	2.9e-02	NA	1.0e-01
12	TCGA	Prostate Adenocarcinoma	0.0526	0.0341	3.1e-06	0.052	0.049	0.049	NA	0.046	3.7e-06	6.5e-06	6.4e-06	NA	1.2e-05
13	TCGA	Stomach Adenocarcinoma	0.0410	0.0320	1.6e-03	0.042	0.040	0.039	NA	0.040	4.8e-04	7.2e-04	8.3e-04	NA	6.7e-04
14	TCGA	Thyroid Carcinoma	0.0370	0.0300	3.2e-04	0.039	0.032	0.033	NA	0.035	9.5e-05	4.1e-04	3.2e-04	NA	2.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Birth weight of first child	6.8	12.3	15.6	-3.6	-3.6	-3.9	-1.6	-2.2	-3.9	-3.0	-3.8	-3.8	-3.8	-3.4	-3.7	-3.8	-4.0
Heart disease (siblings)	6.1	7.4	10.1	2.9	2.7	3.0	0.5	1.6	3.0	2.3	2.8	3.1	3.1	2.8	2.8	3.1	3.2
Medication: Levothyroxine sodium	5.8	9.9	13.2	3.4	3.5	3.6	0.9	2.0	3.6	2.2	3.6	3.6	3.6	2.3	3.0	3.6	3.5
Hypothyroidism/myxoedema (self-reported)	5.4	10.6	15.7	3.6	3.5	3.7	0.4	2.2	3.7	2.7	4.0	3.7	3.7	2.0	3.0	3.7	3.6
Leg pain on walking	4.9	6.2	7.5	2.5	2.6	2.7	0.6	1.9	2.7	2.7	2.2	2.7	2.7	2.7	2.5	2.7	2.6
Pulse rate	4.7	8.0	11.0	3.2	3.1	3.1	2.2	2.8	3.1	0.9	3.3	3.0	3.0	2.1	2.9	3.0	3.0
Average weekly champagne plus white wine intake	4.7	6.5	9.6	-2.9	-2.7	-2.7	-0.8	-2.1	-2.7	-2.4	-3.1	-2.8	-2.8	-1.8	-2.7	-2.8	-2.7
Trunk fat-free mass	4.3	24.6	40.9	-5.2	-5.4	-5.1	-6.4	-6.0	-5.1	-1.0	-6.0	-5.1	-5.1	-2.1	-4.0	-5.1	-5.2
Trunk predicted mass	4.2	24.0	40.2	-5.1	-5.3	-5.0	-6.3	-6.0	-5.0	-0.9	-5.9	-5.0	-5.0	-2.0	-3.9	-5.0	-5.1
Exposure to tobacco smoke outside home	4.2	5.6	7.2	2.5	2.4	2.5	0.7	1.9	2.5	2.2	2.3	2.6	2.6	2.7	2.7	2.6	2.5
Arm predicted mass (right)	4.1	20.8	31.8	-4.8	-5.1	-4.7	-5.5	-5.6	-4.7	-1.2	-5.5	-4.6	-4.6	-1.9	-3.7	-4.6	-4.8
Whole body fat-free mass	4.1	23.3	41.1	-5.0	-5.3	-4.9	-6.4	-5.7	-4.9	-1.2	-5.8	-4.9	-4.9	-2.1	-3.9	-4.9	-5.0
Whole body water mass	4.1	23.2	42.4	-5.0	-5.3	-4.9	-6.5	-5.7	-4.9	-1.1	-5.8	-4.9	-4.9	-2.1	-3.9	-4.9	-5.0
Basal metabolic rate	4.1	22.5	39.9	-4.9	-5.2	-4.8	-6.3	-5.5	-4.8	-1.4	-5.6	-4.8	-4.8	-2.2	-3.9	-4.8	-5.0
Commuting to job workplace: Cycle	4.1	5.0	11.4	-2.3	-2.8	-2.3	-0.9	-3.4	-2.3	-0.8	-2.6	-2.4	-2.4	-0.9	-1.7	-2.4	-2.3
Bilateral oophorectomy (both ovaries removed)	4.0	4.7	10.3	-2.1	-2.3	-2.1	-1.5	-0.2	-2.1	-3.2	-1.7	-2.1	-2.1	-2.7	-2.4	-2.1	-2.1
Arm predicted mass (left)	4.0	20.4	32.0	-4.7	-5.0	-4.6	-5.5	-5.7	-4.6	-1.4	-5.5	-4.6	-4.6	-1.8	-3.6	-4.6	-4.7
Arm fat-free mass (left)	3.9	19.7	31.2	-4.6	-4.9	-4.5	-5.6	-5.3	-4.5	-1.1	-5.4	-4.5	-4.5	-1.7	-3.5	-4.5	-4.7
Sitting height	3.8	27.3	40.6	-5.2	-5.7	-5.4	-6.4	-6.2	-5.4	-1.8	-5.8	-5.4	-5.4	-3.1	-4.6	-5.4	-5.4
Leg predicted mass (right)	3.8	20.1	39.7	-4.6	-5.0	-4.5	-6.3	-4.9	-4.5	-1.3	-5.3	-4.5	-4.5	-2.1	-3.8	-4.5	-4.7
Hypothyroidism (self reported)	3.7	8.4	14.2	3.2	3.2	3.3	1.4	2.6	3.3	1.8	3.8	3.2	3.2	1.2	2.5	3.2	3.1
Medication: Simvastatin	3.7	5.5	6.9	2.3	2.5	2.6	2.1	2.0	2.6	1.1	2.5	2.6	2.6	1.8	2.2	2.6	2.6
Alcohol intake frequency.	3.7	8.5	11.6	3.0	3.2	3.0	-0.7	1.8	3.0	3.4	2.7	3.0	3.0	3.4	3.3	3.0	3.0
Leg fat-free mass (right)	3.7	19.8	39.8	-4.6	-4.9	-4.5	-6.3	-4.8	-4.5	-1.3	-5.3	-4.4	-4.4	-2.1	-3.7	-4.4	-4.6
Arm fat-free mass (right)	3.6	18.3	27.6	-4.5	-4.7	-4.4	-5.1	-5.2	-4.4	-1.1	-5.2	-4.4	-4.4	-1.7	-3.5	-4.4	-4.5
Leg fat-free mass (left)	3.5	18.5	40.3	-4.4	-4.8	-4.3	-6.3	-4.7	-4.3	-1.2	-5.0	-4.2	-4.2	-2.0	-3.6	-4.2	-4.5
Ovarian Cancer	3.4	4.5	7.7	-2.0	-2.4	-2.1	-2.2	-2.8	-2.1	-0.9	-2.0	-2.1	-2.1	-1.9	-2.1	-2.1	-2.2
Supplements: Glucosamine	3.4	4.4	5.6	-2.1	-2.0	-2.2	-2.0	-0.1	-2.2	-2.4	-1.9	-2.2	-2.2	-2.3	-2.3	-2.2	-2.1
Leg predicted mass (left)	3.4	17.9	39.8	-4.3	-4.7	-4.2	-6.3	-4.6	-4.2	-1.1	-5.0	-4.2	-4.2	-2.0	-3.5	-4.2	-4.4
Hip circumference	3.4	14.5	21.5	-4.0	-4.1	-3.9	-4.6	-4.1	-3.9	-2.1	-4.5	-3.9	-3.9	-2.0	-3.3	-3.9	-4.0
Irritable Bowel Disease (IBD)	3.3	7.9	9.3	-3.0	-3.0	-2.9	-1.7	-2.6	-2.9	-2.6	-2.8	-3.0	-3.0	-2.6	-2.9	-3.0	-2.9
Hair/balding pattern: Pattern 2	3.3	4.2	13.1	2.1	2.4	2.1	0.8	3.6	2.1	-0.4	2.4	2.1	2.1	0.6	1.5	2.1	2.0
Age at first live birth	3.2	5.6	10.2	-2.6	-2.7	-2.5	-1.2	-3.2	-2.5	-1.0	-2.7	-2.5	-2.5	-1.6	-2.3	-2.5	-2.4
Weight	3.1	15.1	29.3	-4.0	-4.3	-3.9	-5.4	-3.9	-3.9	-2.1	-4.5	-3.9	-3.9	-2.2	-3.4	-3.9	-4.0
Comparative height size at age 10	3.1	17.3	29.5	-4.1	-4.5	-4.3	-5.4	-5.0	-4.3	0.4	-4.8	-4.3	-4.3	-2.0	-3.4	-4.3	-4.3
Forced expiratory volume in 1-second (FEV1), predicted	3.0	6.2	7.6	-2.7	-2.6	-2.6	-2.7	-2.8	-2.6	-1.1	-2.7	-2.6	-2.6	-2.0	-2.4	-2.6	-2.7
Osteoporosis (self-reported)	3.0	3.7	5.6	2.1	2.3	1.9	2.4	1.4	1.9	1.1	2.0	2.0	2.0	1.6	1.9	2.0	1.9
Had other major operations	2.9	3.5	4.7	-2.0	-2.2	-1.9	-1.5	-2.1	-1.9	-1.5	-2.2	-1.9	-1.9	-1.3	-1.8	-1.9	-1.9
Standing height	2.8	27.9	44.2	-5.4	-5.7	-5.5	-5.6	-6.6	-5.5	-1.6	-6.0	-5.5	-5.5	-3.2	-4.7	-5.5	-5.5
Handedness (chirality/laterality): Left-handed	2.8	3.3	8.1	1.6	1.8	1.8	1.1	0.3	1.8	2.9	1.5	1.8	1.8	2.3	2.0	1.8	1.9
Verbal and Numeric Reasoning (VNR)	2.7	6.4	8.2	-2.5	-2.9	-2.8	-2.4	-2.8	-2.8	-0.4	-2.8	-2.8	-2.8	-1.6	-2.2	-2.8	-2.7
Medication: Co-codamol	2.7	3.1	4.7	1.8	2.1	2.0	-1.3	1.9	2.0	0.9	2.2	2.0	2.0	0.7	1.4	2.0	1.8
Pack years adult smoking proportion	2.7	4.2	5.5	2.0	2.0	2.4	0.9	0.6	2.4	2.0	1.9	2.4	2.4	2.2	2.0	2.4	2.3
Medication: Lansoprazole	2.7	3.1	4.0	1.8	1.7	2.0	0.6	0.7	2.0	1.9	1.9	1.9	1.9	1.6	1.9	1.9	1.9
Pulse rate, automated reading	2.7	8.7	19.9	3.0	2.9	2.9	3.8	4.5	2.9	-0.1	3.4	2.8	2.8	1.6	2.8	2.8	2.7
Ulcerative Colitis (UC)	2.6	4.8	6.4	-2.5	-2.3	-2.3	-1.4	-2.2	-2.3	-1.4	-2.4	-2.3	-2.3	-1.9	-2.2	-2.3	-2.4
Crohns Disease (2012)	2.6	4.2	6.7	-2.1	0.0	-2.1	-1.3	-1.3	-2.1	-2.0	-2.1	-2.3	-2.3	-2.6	-2.5	-2.3	-2.3
Pack years of smoking	2.6	3.7	5.0	1.9	2.0	2.2	0.7	1.0	2.2	1.8	1.8	2.2	2.2	1.9	1.9	2.2	2.2
Systolic Blood Pressure	2.4	11.8	26.6	3.5	3.4	3.6	2.8	5.2	3.6	0.0	4.1	3.7	3.7	1.4	2.7	3.7	3.7
Alcohol usually taken with meals	2.4	3.9	5.0	-2.1	-1.8	-2.2	-1.1	-1.5	-2.2	-1.4	-2.0	-2.2	-2.2	-2.0	-2.2	-2.2	-2.0
Birth weight	2.4	5.3	7.6	-2.7	-2.2	-2.5	-0.8	-2.2	-2.5	-1.5	-2.8	-2.5	-2.5	-1.8	-2.5	-2.5	-2.5
Forced vital capacity (FVC), Best measure	2.4	8.8	10.5	-3.1	-3.2	-3.2	-2.6	-2.5	-3.2	-2.0	-3.1	-3.1	-3.1	-2.8	-3.1	-3.1	-3.2
Medication: Allopurinol	2.4	3.2	7.3	1.8	2.2	1.8	1.5	2.7	1.8	0.6	2.1	1.8	1.8	0.9	1.6	1.8	1.8
Intelligence (Savage-Jansen 2018)	2.3	7.0	9.1	-2.8	-2.9	-2.9	-1.6	-2.7	-2.9	-0.6	-3.0	-3.0	-3.0	-1.9	-2.5	-3.0	-2.9
Maternal smoking around birth	2.3	3.3	4.5	1.9	2.0	2.1	0.2	2.1	2.1	0.5	2.1	2.0	2.0	1.1	1.7	2.0	2.0
Alcohol drinker status: Previous	2.3	2.6	4.7	1.7	2.2	1.8	-0.8	1.5	1.8	0.7	1.9	1.8	1.8	0.9	1.3	1.8	2.0
Schizophrenia vs Biploar Disorder	2.2	2.9	5.1	1.7	1.3	1.8	-1.0	-0.6	1.8	1.8	1.4	1.9	1.9	2.2	1.9	1.9	1.8
Hair/balding pattern: Pattern 4	2.2	5.3	6.6	-2.3	-2.6	-2.4	-2.4	-2.2	-2.4	-1.0	-2.2	-2.4	-2.4	-2.3	-2.4	-2.4	-2.4
Heel T-Score	2.1	16.7	19.7	4.4	4.1	4.3	4.4	4.1	4.3	1.5	4.4	4.4	4.4	3.3	4.1	4.4	4.2
Number of operations (self-reported)	2.1	3.1	9.9	-1.6	-1.8	-1.6	0.2	0.4	-1.6	-3.1	-1.2	-1.6	-1.6	-2.6	-2.1	-1.6	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	2.0	4.5	8.2	2.2	2.1	2.2	2.1	2.9	2.2	0.3	2.5	2.1	2.1	1.5	2.2	2.1	2.1
Blood clot in the leg (DVT)	2.0	2.6	3.9	1.7	1.7	1.7	0.5	1.0	1.7	2.0	1.4	1.6	1.6	1.9	1.7	1.6	1.7
Ulcerative Colitis	1.9	2.7	3.8	-1.9	-1.6	-1.7	-0.0	-1.9	-1.7	-1.1	-1.9	-1.8	-1.8	-1.2	-1.7	-1.8	-1.8
Height	1.9	36.5	59.7	-6.2	-6.2	-6.2	-7.7	-7.2	-6.2	-1.4	-6.7	-6.1	-6.1	-4.1	-5.6	-6.1	-6.2
Waist Hip Ratio (WHR)	1.9	8.3	23.2	2.9	2.7	2.9	4.8	2.4	2.9	1.3	3.1	2.9	2.9	1.9	2.7	2.9	2.8
Allergy or Eczema	1.9	5.1	8.9	-2.4	-1.8	-2.3	-1.5	0.5	-2.3	-3.0	-2.2	-2.4	-2.4	-2.6	-2.6	-2.4	-2.4
Medication: Bendroflumethiazide	1.9	2.8	4.4	-1.7	-1.9	-1.7	0.2	-0.8	-1.7	-1.7	-1.6	-1.8	-1.8	-2.1	-2.1	-1.8	-1.7
Number of full brothers	1.8	2.3	3.0	1.5	1.6	1.7	-0.2	0.1	1.7	1.3	1.6	1.7	1.7	1.6	1.7	1.7	1.7
Alzheimer’s Disease (including proxy)	1.7	2.4	12.1	1.2	1.4	1.3	3.5	1.6	1.3	0.8	1.0	1.4	1.4	1.4	1.3	1.4	1.1
Forced vital capacity (FVC)	1.7	6.7	9.6	-2.6	-2.8	-2.7	-3.1	-2.3	-2.7	-1.3	-2.6	-2.7	-2.7	-2.3	-2.5	-2.7	-2.7
Alcohol drinker status: Never	1.7	2.0	3.1	1.4	1.4	1.6	0.7	0.6	1.6	1.8	1.5	1.6	1.6	1.2	1.4	1.6	1.5
Unable to work because of sickness or disability	1.7	2.2	4.6	1.4	1.6	1.7	0.4	2.1	1.7	0.6	1.7	1.6	1.6	0.7	1.2	1.6	1.5
Angina	1.6	2.0	4.1	1.5	1.2	1.5	0.1	2.0	1.5	1.1	1.8	1.6	1.6	0.6	1.2	1.6	1.6
Hayfever, allergic rhinitis or eczema	1.6	3.5	6.2	-1.9	-1.5	-1.9	-1.0	0.7	-1.9	-2.5	-1.6	-1.9	-1.9	-2.4	-2.1	-1.9	-2.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.2	6.6	-2.4	-2.6	-2.5	-1.4	-1.3	-2.5	-2.0	-2.2	-2.4	-2.4	-2.4	-2.4	-2.4	-2.5
Medication: Omeprazole	1.6	1.9	4.1	-1.4	-1.3	-1.4	0.3	0.3	-1.4	-1.3	-1.2	-1.4	-1.4	-2.0	-1.8	-1.4	-1.4
Heart disease (mother)	1.6	1.9	3.5	1.5	1.7	1.5	0.4	1.9	1.5	0.5	1.7	1.4	1.4	0.5	1.1	1.4	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	2.6	1.5	1.5	1.4	1.5	1.6	1.4	0.6	1.6	1.5	1.5	0.7	1.2	1.5	1.4
Wears glasses or contact lenses	1.6	1.9	2.7	-1.4	-1.4	-1.5	-1.5	-0.1	-1.5	-1.0	-1.7	-1.5	-1.5	-0.9	-1.3	-1.5	-1.4
Risk taking	1.6	2.4	3.8	-1.8	-1.8	-1.7	-0.7	-1.9	-1.7	-0.9	-1.9	-1.6	-1.6	-0.7	-1.4	-1.6	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.4	4.6	1.9	1.9	1.9	1.7	2.0	1.9	0.6	2.1	1.9	1.9	1.5	2.0	1.9	1.9
Qualifications: None of the above	1.5	3.2	4.5	1.9	1.9	2.1	-0.2	0.8	2.1	2.0	2.0	2.1	2.1	0.9	1.3	2.1	2.0
Leg fat mass (right)	1.5	6.0	12.7	-2.5	-2.6	-2.4	-3.6	-1.8	-2.4	-2.2	-2.5	-2.3	-2.3	-2.0	-2.3	-2.3	-2.5
Age at last live birth	1.5	2.2	4.4	-1.8	-1.7	-1.6	-0.0	-2.1	-1.6	0.1	-2.0	-1.6	-1.6	-0.5	-1.3	-1.6	-1.4
Financial situation satisfaction	1.5	1.8	7.3	1.3	1.2	1.4	0.1	2.7	1.4	-0.7	1.5	1.4	1.4	0.5	1.0	1.4	1.2
Average weekly beer plus cider intake	1.5	2.1	3.0	1.4	1.4	1.7	0.2	0.8	1.7	1.6	1.7	1.7	1.7	0.9	1.3	1.7	1.6
Leg fat mass (left)	1.5	5.8	11.8	-2.4	-2.6	-2.3	-3.4	-1.9	-2.3	-2.2	-2.5	-2.3	-2.3	-1.9	-2.2	-2.3	-2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	5.8	0.9	1.3	1.3	-0.3	0.1	1.3	2.4	0.9	1.3	1.3	1.5	1.3	1.3	1.2
Whole body fat mass	1.4	6.0	13.4	-2.4	-2.7	-2.4	-3.7	-2.0	-2.4	-2.0	-2.6	-2.4	-2.4	-1.9	-2.3	-2.4	-2.5
Supplements: Fish oil (including cod liver oil)	1.4	1.9	6.6	1.6	1.5	1.3	0.5	2.6	1.3	-0.1	1.8	1.4	1.4	0.2	1.0	1.4	1.3
Severe depression (siblings)	1.3	1.4	3.3	1.1	1.2	1.1	1.4	0.4	1.1	1.8	0.6	1.1	1.1	1.6	1.3	1.1	1.0
Trunk fat mass	1.3	5.8	12.9	-2.4	-2.6	-2.3	-3.6	-1.7	-2.3	-2.1	-2.4	-2.3	-2.3	-2.0	-2.3	-2.3	-2.5
Fluid intelligence score	1.3	2.6	4.0	-1.4	-2.0	-1.9	-1.5	-1.9	-1.9	-0.1	-1.8	-1.9	-1.9	-0.6	-1.0	-1.9	-1.7
Illnesses of siblings	1.3	1.8	3.4	-1.4	-1.1	-1.5	0.1	-1.9	-1.5	-0.3	-1.6	-1.5	-1.5	-0.9	-1.3	-1.5	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.5	1.5	0.8	1.4	-2.1	0.0	1.4	1.8	1.5	1.4	1.4	1.0	1.4	1.4	1.3
High blood pressure (siblings)	1.3	1.8	9.7	1.1	1.3	1.2	1.0	3.1	1.2	-0.6	1.7	1.2	1.2	-0.4	0.6	1.2	1.2
Qualifications: College or University degree	1.3	4.2	6.0	-2.3	-2.4	-2.3	-0.2	-1.8	-2.3	-1.9	-2.4	-2.3	-2.3	-1.1	-2.0	-2.3	-1.9
Mean time to correctly identify matches	1.3	2.4	4.6	1.3	1.9	1.6	0.3	2.2	1.6	0.8	1.5	1.6	1.6	1.6	1.7	1.6	1.6
Illnesses of father: None of the above (group 1)	1.3	1.6	3.3	-1.5	-1.2	-1.4	0.4	-1.1	-1.4	-1.2	-1.8	-1.3	-1.3	-0.4	-1.2	-1.3	-1.3
Crohns Disease (2017)	1.2	2.7	4.4	-1.6	-1.6	-1.7	-0.6	-0.7	-1.7	-2.1	-1.5	-1.9	-1.9	-1.7	-1.7	-1.9	-1.6
Blood Platelet Count	1.2	13.8	29.7	3.5	4.0	3.8	5.5	4.0	3.8	1.0	4.3	3.8	3.8	1.8	3.1	3.8	3.8
Systolic blood pressure, automated reading	1.2	3.5	8.0	1.8	1.8	2.0	1.4	2.8	2.0	-0.1	2.2	2.0	2.0	0.7	1.4	2.0	2.0
Medication: Atenolol	1.2	1.6	5.5	1.3	1.2	1.1	0.9	2.3	1.1	-0.4	1.7	1.3	1.3	-0.2	0.7	1.3	1.2
Forced expiratory volume in 1-second (FEV1)	1.2	4.0	5.2	-2.0	-2.3	-2.1	-2.2	-1.4	-2.1	-1.4	-1.8	-2.1	-2.1	-2.1	-2.0	-2.1	-2.1
Impedance of arm (left)	1.2	5.5	9.7	2.5	2.5	2.4	3.0	3.0	2.4	0.1	3.1	2.4	2.4	0.2	1.6	2.4	2.5
Loud music exposure frequency	1.2	1.3	2.0	1.4	0.8	1.3	0.7	-0.0	1.3	0.4	1.4	1.4	1.4	0.9	1.2	1.4	1.4
Number of full sisters	1.2	1.5	2.1	1.3	1.3	1.3	1.2	0.7	1.3	0.4	1.2	1.4	1.4	1.3	1.4	1.4	1.2
Medication: Blood pressure	1.2	2.2	4.8	-1.5	-1.8	-1.4	-1.3	-0.4	-1.4	-1.9	-1.1	-1.3	-1.3	-2.2	-1.8	-1.3	-1.4
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	3.4	-1.2	-1.1	-1.2	0.6	0.5	-1.2	-1.4	-1.0	-1.2	-1.2	-1.8	-1.5	-1.2	-1.3
Waist circumference	1.1	4.2	6.2	-2.3	-2.2	-2.1	-2.1	-1.6	-2.1	-1.7	-2.5	-2.1	-2.1	-1.3	-1.9	-2.1	-2.2
Impedance of arm (right)	1.1	4.9	8.6	2.4	2.5	2.3	2.7	2.9	2.3	0.1	2.9	2.2	2.2	0.4	1.6	2.2	2.3
Tense / ‘highly strung’	1.1	1.8	2.7	-1.6	-1.1	-1.5	-0.9	-0.3	-1.5	-0.4	-1.5	-1.5	-1.5	-1.6	-1.6	-1.5	-1.6
Number of children fathered	1.1	1.2	3.6	-1.0	-0.9	-1.0	-1.1	-0.5	-1.0	-1.3	-0.5	-1.1	-1.1	-1.9	-1.4	-1.1	-0.9
Angina (self-reported)	1.1	1.5	3.4	1.3	1.0	1.3	-0.0	1.9	1.3	0.9	1.6	1.3	1.3	0.4	1.0	1.3	1.3
Loneliness, isolation	1.1	1.5	6.1	-1.1	-1.4	-1.0	-2.5	-1.4	-1.0	-0.1	-1.1	-1.1	-1.1	-0.9	-1.0	-1.1	-1.2
Arm fat mass (left)	1.1	4.5	14.7	-2.0	-2.3	-1.9	-3.8	-1.7	-1.9	-1.4	-2.2	-1.9	-1.9	-1.3	-1.8	-1.9	-2.1
Ever taken oral contraceptive pill	1.1	1.2	1.6	-1.2	-1.0	-1.1	-1.1	-0.6	-1.1	-1.3	-1.3	-1.1	-1.1	-0.8	-1.1	-1.1	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	2.4	1.2	1.2	1.2	0.2	0.6	1.2	1.6	1.0	1.2	1.2	1.5	1.3	1.2	1.3
BMI	1.0	5.8	18.1	-2.4	-2.8	-2.3	-4.2	-1.9	-2.3	-1.9	-2.5	-2.2	-2.2	-1.3	-1.9	-2.2	-2.4
Father’s age at death	1.0	1.3	6.9	-1.0	-0.5	-1.1	2.6	-0.8	-1.1	-1.2	-1.0	-0.9	-0.9	-0.6	-0.8	-0.9	-1.0
Medication: Cholesterol lowering	1.0	1.6	4.9	1.2	1.5	1.3	0.7	2.2	1.3	0.3	1.6	1.3	1.3	0.0	0.8	1.3	1.2
Worry too long after embarrassment	1.0	1.7	3.8	1.5	1.6	1.2	-0.3	2.0	1.2	0.8	1.4	1.3	1.3	1.3	1.6	1.3	1.2
Myopia	1.0	1.4	2.2	-1.2	-1.2	-1.4	-1.2	-0.5	-1.4	-0.8	-1.5	-1.4	-1.4	-0.5	-1.0	-1.4	-1.4
Bipolar Disorder (2018)	0.9	1.4	2.2	-1.2	-1.3	-1.4	-0.6	-0.9	-1.4	0.5	-1.5	-1.4	-1.4	-0.5	-0.9	-1.4	-1.5
Alzheimer’s Disease (in mother)	0.9	1.0	6.1	0.7	0.8	0.7	2.5	1.1	0.7	0.9	0.3	0.6	0.6	1.2	0.9	0.6	0.5
Age at First Birth	0.9	1.3	6.2	-1.1	-1.0	-0.9	-0.0	-2.5	-0.9	1.0	-1.4	-1.0	-1.0	-0.1	-0.8	-1.0	-1.1
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	4.5	-0.5	-1.1	-0.8	-2.1	-1.8	-0.8	0.3	-0.8	-0.8	-0.8	-0.2	-0.4	-0.8	-0.8
Nervous feelings	0.9	1.6	5.1	1.4	1.4	1.3	0.5	2.3	1.3	0.3	1.8	1.2	1.2	-0.1	0.9	1.2	1.1
Worrier / anxious feelings	0.9	1.6	4.2	-0.8	-1.2	-1.3	-1.1	0.1	-1.3	-1.2	-0.7	-1.4	-1.4	-2.0	-1.2	-1.4	-1.6
Arm fat mass (right)	0.9	3.9	15.1	-1.8	-2.2	-1.7	-3.9	-1.6	-1.7	-1.4	-2.0	-1.7	-1.7	-1.1	-1.5	-1.7	-1.9
Exposure to tobacco smoke at home	0.9	1.0	1.4	0.9	1.2	1.0	1.1	1.2	1.0	0.7	0.8	1.0	1.0	1.0	1.0	1.0	0.9
Pulse wave reflection index	0.9	1.1	1.9	-1.2	-1.3	-1.0	-0.8	-0.5	-1.0	-0.8	-1.0	-1.0	-1.0	-1.4	-1.4	-1.0	-1.0
Illnesses of father: Heart disease	0.9	1.3	4.0	1.2	0.9	1.1	-2.0	0.6	1.1	1.2	1.5	1.1	1.1	0.2	0.9	1.1	1.0
Average weekly red wine intake	0.9	1.4	1.9	-1.4	-1.2	-1.3	0.3	-1.3	-1.3	-0.7	-1.1	-1.2	-1.2	-1.2	-1.3	-1.2	-1.2
High cholesterol (Self-reported)	0.9	1.6	5.9	1.4	1.4	1.2	0.5	2.4	1.2	-0.0	1.6	1.2	1.2	0.3	1.1	1.2	1.1
Impedance of whole body	0.9	4.8	19.5	2.1	2.2	1.9	4.4	2.7	1.9	-0.9	2.7	1.9	1.9	-0.2	1.2	1.9	2.0
Hand grip strength (right)	0.8	2.2	2.9	-1.4	-1.7	-1.7	-1.2	-1.5	-1.7	-0.9	-1.3	-1.6	-1.5	-1.6	-1.4	-1.5	-1.7
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	1.3	-1.1	-0.8	-1.1	-0.2	-1.1	-1.1	-0.8	-0.9	-1.1	-1.1	-0.9	-0.9	-1.1	-1.1
Noisy workplace	0.8	0.9	1.5	0.9	0.8	1.2	-0.2	-0.9	1.2	1.1	0.9	1.1	1.1	0.6	0.7	1.1	1.0
Health satisfaction	0.8	1.1	5.3	0.9	1.0	1.0	0.0	2.3	1.0	-0.2	1.4	1.0	1.0	-0.8	0.2	1.0	0.8
Ever had bowel cancer screening	0.8	0.9	1.6	-0.8	-0.9	-1.0	-1.2	-1.3	-1.0	-0.7	-1.0	-1.0	-1.0	-0.5	-0.7	-1.0	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	1.5	-1.0	-1.2	-0.9	-0.7	-0.9	-0.9	-0.6	-0.9	-0.9	-0.9	-1.1	-1.1	-0.9	-0.9
Commuting to job workplace: Walk	0.8	0.9	1.6	-0.9	-0.8	-1.0	0.9	0.7	-1.0	-1.3	-1.0	-1.0	-1.0	-0.4	-0.7	-1.0	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	1.4	-0.9	-1.2	-1.1	1.1	-1.1	-1.1	-1.1	-1.0	-1.2	-1.2	-1.1	-1.0	-1.2	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	2.1	-0.8	-1.0	-1.0	-1.3	0.2	-1.0	-1.0	-0.5	-0.8	-0.8	-1.4	-1.1	-0.8	-0.8
Body Mass Index (BMI) (2010)	0.7	0.9	4.3	-0.5	-1.3	-0.6	-1.9	-2.1	-0.6	-0.2	-0.8	-0.6	-0.6	0.0	-0.3	-0.6	-0.6
Mean Putamen Volume	0.7	0.8	1.4	0.7	1.2	0.9	0.7	1.0	0.9	0.1	0.7	0.9	0.9	1.0	0.9	0.9	0.9
HDL Cholesterol	0.7	1.1	9.3	0.7	0.8	0.4	3.0	1.3	0.4	-0.5	0.7	0.5	0.5	0.5	0.8	0.5	0.6
Medication: Ramipril	0.7	0.9	1.6	-1.1	-1.3	-1.0	-0.5	-0.6	-1.0	-0.7	-1.3	-1.1	-1.1	-0.5	-0.9	-1.1	-1.0
Time employed in main current job	0.7	0.9	1.7	1.1	0.9	1.0	0.0	1.3	1.0	0.6	1.3	1.0	1.0	0.1	0.6	1.0	1.0
Depression (self-reported)	0.7	0.9	3.9	0.8	0.7	0.8	-2.0	-0.4	0.8	1.6	0.7	0.6	0.6	0.7	0.8	0.6	0.6
Gout (self-reported)	0.7	0.9	1.7	0.9	1.3	1.0	0.3	1.3	1.0	0.5	1.1	1.0	1.0	0.6	0.8	1.0	1.1
Pulse wave peak to peak time	0.7	0.8	1.5	-1.0	-0.7	-1.1	0.5	-1.0	-1.1	0.3	-1.2	-1.0	-1.0	-0.2	-0.7	-1.0	-1.1
Medication for cholesterol	0.7	1.0	2.1	1.0	1.4	1.0	1.3	0.3	1.0	0.9	0.7	0.9	0.9	1.4	1.1	0.9	1.0
Basal cell carcinoma (self-reported)	0.7	0.8	1.4	-1.1	-0.9	-1.0	-0.5	-1.2	-1.0	-0.1	-1.0	-1.0	-1.0	-0.6	-0.8	-1.0	-1.0
Breast Cancer	0.6	1.5	2.3	1.5	1.3	1.3	1.5	0.4	1.3	1.4	1.2	1.2	1.2	1.0	1.2	1.2	1.2
Blood Eosinophil Count	0.6	4.9	6.5	-2.5	-2.4	-2.4	-1.7	-1.1	-2.4	-1.9	-2.4	-2.4	-2.4	-2.0	-2.3	-2.4	-2.4
Average weekly spirits intake	0.6	0.7	2.3	-0.9	-1.1	-0.6	0.3	-1.5	-0.6	-0.5	-0.6	-0.7	-0.7	-1.1	-1.0	-0.7	-0.6
Supplements: Zinc	0.6	0.6	1.3	0.7	1.1	0.8	0.4	0.8	0.8	0.4	0.8	0.7	0.7	1.1	1.1	0.7	0.7
Impedance of leg (right)	0.6	2.9	19.0	1.3	1.6	1.2	4.4	1.6	1.2	-0.9	2.0	1.2	1.2	-0.5	0.7	1.2	1.3
High blood pressure	0.6	1.5	4.4	-1.2	-1.2	-1.0	-0.6	1.6	-1.0	-1.5	-0.7	-1.0	-1.0	-2.1	-1.5	-1.0	-1.1
Body mass index (BMI)	0.6	2.5	9.6	-1.6	-1.7	-1.4	-3.1	-1.0	-1.4	-1.2	-1.8	-1.4	-1.4	-0.7	-1.3	-1.4	-1.6
Impedance of leg (left)	0.6	2.7	22.8	1.1	1.3	1.0	4.8	1.2	1.0	-1.3	1.6	0.9	0.9	-0.5	0.5	0.9	1.1
Falls in the last year	0.6	0.9	1.8	0.8	0.9	1.0	1.2	1.4	1.0	0.1	0.7	0.9	0.9	0.9	0.8	0.9	0.9
Overall health rating	0.6	1.2	8.5	0.8	0.7	0.9	-0.9	2.9	0.9	-0.6	1.2	0.9	0.9	-0.5	0.4	0.9	0.6
Commuting to job workplace: Car/motor vehicle	0.6	0.7	3.1	-0.5	-0.6	-0.5	-1.3	0.6	-0.5	-0.9	0.0	-0.6	-0.6	-1.8	-0.9	-0.6	-0.7
Hypertension (Self-reported)	0.6	1.7	4.3	-1.3	-1.3	-1.1	-1.0	1.4	-1.1	-1.5	-0.8	-1.1	-1.1	-2.1	-1.6	-1.1	-1.2
Smoking status: Current	0.6	1.0	1.5	1.0	0.7	1.1	1.2	-0.7	1.1	1.1	0.9	1.1	1.1	0.8	0.9	1.1	1.0
Leg fat percentage (left)	0.6	2.2	5.7	-1.4	-1.6	-1.4	-1.5	-0.8	-1.4	-2.4	-1.3	-1.4	-1.4	-1.7	-1.5	-1.4	-1.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.2	-0.9	-0.7	-1.0	0.1	-0.4	-1.0	-1.1	-1.0	-1.0	-1.0	-0.6	-0.9	-1.0	-0.8
Depressed Affect (Nagel 2018)	0.5	1.0	6.3	-0.8	-0.9	-0.7	-2.5	-0.6	-0.7	-0.1	-0.6	-0.9	-0.9	-1.0	-0.7	-0.9	-0.9
Schizophrenia (2018)	0.5	1.0	2.8	0.9	1.1	0.9	-1.0	0.1	0.9	1.3	0.5	0.9	0.9	1.7	1.3	0.9	0.8
Primary Biliary Cirrhosis	0.5	0.7	1.5	0.7	0.7	0.8	0.8	-0.2	0.8	1.2	0.7	1.0	1.0	0.6	0.5	1.0	0.9
Lung FEV1/FVC ratio	0.5	2.7	10.4	1.5	1.5	1.4	3.2	2.5	1.4	0.2	1.7	1.4	1.4	0.7	1.2	1.4	1.5
Number of treatments/medications taken	0.5	0.9	4.6	-0.3	-0.1	-0.2	-1.0	1.9	-0.2	-1.5	0.3	-0.2	-0.2	-2.1	-1.1	-0.2	-0.4
Current tobacco smoking	0.5	0.8	1.1	0.9	0.6	1.0	0.7	-0.8	1.0	1.1	0.9	1.0	1.0	0.8	0.8	1.0	0.9
Qualifications: CSEs or equivalent	0.5	0.7	2.6	0.4	0.7	0.5	1.2	1.6	0.5	-1.5	0.8	0.5	0.5	-0.4	0.2	0.5	0.4
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.4	-1.0	-0.8	-0.8	-0.3	0.6	-0.8	-0.9	-0.6	-0.8	-0.8	-1.2	-0.9	-0.8	-1.0
Leg fat percentage (right)	0.5	1.9	4.6	-1.3	-1.4	-1.2	-1.6	-0.4	-1.2	-2.1	-1.1	-1.2	-1.2	-1.6	-1.4	-1.2	-1.4
Had major operations	0.5	0.5	2.5	0.6	0.7	0.5	1.2	1.6	0.5	-0.4	0.9	0.5	0.5	0.1	0.4	0.5	0.7
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.5	0.8	0.8	0.8	-1.2	-0.7	0.8	1.1	0.6	0.7	0.7	0.5	0.5	0.7	0.7
Breast cancer (self-reported)	0.5	0.6	1.7	0.6	0.6	0.7	0.9	0.9	0.7	1.3	0.6	0.7	0.7	0.9	0.7	0.7	0.7
Guilty feelings	0.5	0.8	4.5	-0.9	-1.1	-0.7	-2.1	0.1	-0.7	0.3	-0.9	-0.7	-0.7	-0.2	-0.5	-0.7	-0.8
Hearing aid user	0.5	0.6	1.1	-0.8	-1.0	-0.7	-0.4	-0.6	-0.7	-1.0	-0.6	-0.8	-0.8	-0.9	-1.0	-0.8	-0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	3.3	-0.6	-0.7	-0.7	-1.8	-0.2	-0.7	0.3	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.8
Depression (Nagel 2018)	0.4	0.6	3.6	0.7	0.2	0.7	-1.9	0.0	0.7	1.1	0.8	0.7	0.7	-0.0	0.6	0.7	0.3
Major Depression (MDD)	0.4	0.4	1.5	0.4	0.1	0.5	0.1	-0.5	0.5	1.2	0.4	0.6	0.6	1.1	0.8	0.6	0.6
Fasting Glucose	0.4	0.5	2.6	-0.6	-0.3	-0.6	-0.3	-1.6	-0.6	0.7	-1.0	-0.6	-0.6	0.9	-0.1	-0.6	-0.3
Rheumatoid Arthritis	0.4	0.6	4.1	0.3	0.5	0.3	-0.6	2.0	0.3	-1.2	0.7	0.3	0.3	-1.0	-0.3	0.3	0.3
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.5	-0.6	-0.6	-0.4	-1.2	-0.7	-0.4	-0.5	-0.3	-0.4	-0.4	-0.9	-0.8	-0.4	-0.5
Hearing difficulty/problems: Yes	0.4	0.6	2.6	0.6	0.7	0.7	0.8	1.6	0.7	-0.3	0.7	0.7	0.7	0.2	0.4	0.7	0.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.8	0.5	0.1	0.3	0.1	-1.4	0.3	1.4	0.3	0.4	0.4	0.5	0.6	0.4	0.3
Age when periods started (menarche)	0.4	0.9	5.2	0.6	0.9	0.9	2.3	0.2	0.9	-0.0	0.8	1.0	1.0	0.5	0.6	1.0	0.8
Mouth/teeth dental problems	0.4	0.5	2.4	-0.5	-0.1	-0.6	-1.6	-1.1	-0.6	0.8	-1.0	-0.5	-0.5	0.3	-0.2	-0.5	-0.7
Allergy	0.4	0.9	3.7	0.8	0.5	0.8	-0.2	-0.9	0.8	1.9	0.6	0.9	0.9	1.2	1.0	0.9	0.9
Prospective memory result	0.4	0.5	1.5	0.6	0.4	0.8	-0.5	-0.0	0.8	1.2	0.8	0.8	0.8	0.2	0.3	0.8	0.9
Illnesses of mother	0.4	0.5	2.5	-0.8	-0.8	-0.7	-0.1	-1.6	-0.7	-0.1	-0.6	-0.6	-0.6	-0.3	-0.5	-0.6	-0.6
Breastfed as a baby	0.4	0.5	1.5	0.8	0.9	0.7	-0.3	1.2	0.7	0.3	0.8	0.6	0.6	0.3	0.5	0.6	0.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	2.1	0.5	0.7	0.6	1.4	0.8	0.6	1.0	0.5	0.6	0.6	0.9	0.7	0.6	0.7
Body fat percentage	0.4	1.5	4.6	-1.0	-1.2	-1.0	-1.7	-0.0	-1.0	-2.1	-0.9	-1.0	-1.0	-1.5	-1.3	-1.0	-1.1
Wheeze or whistling in the chest in last year	0.4	0.7	4.9	0.1	-0.2	0.1	2.2	0.9	0.1	-1.8	0.4	0.1	0.1	-0.5	0.0	0.1	0.0
Family relationship satisfaction	0.4	0.5	1.9	0.4	0.6	0.5	-1.4	0.7	0.5	1.1	0.4	0.5	0.5	0.6	0.6	0.5	0.4
Miserableness	0.4	0.8	1.5	-0.7	-1.1	-0.9	-1.2	-0.4	-0.9	-0.2	-0.8	-1.0	-1.0	-0.5	-0.5	-1.0	-1.1
Medication: Lisinopril	0.4	0.5	0.8	-0.8	-0.7	-0.8	-0.5	0.3	-0.8	-0.4	-0.6	-0.7	-0.7	-0.9	-0.9	-0.7	-0.7
Age started oral contraceptive pill	0.4	0.5	4.2	-0.2	0.1	-0.3	-0.9	-0.2	-0.3	2.1	-0.8	-0.3	-0.3	1.2	0.3	-0.3	-0.2
Ever depressed for a whole week	0.4	0.5	3.0	-0.0	-0.4	-0.1	-1.4	-1.7	-0.1	1.2	-0.2	-0.1	-0.1	0.4	0.2	-0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.4	0.9	1.0	0.8	0.7	-1.4	0.8	1.3	0.5	0.8	0.8	1.8	1.3	0.8	0.8
Pain experienced in last month	0.4	0.7	4.4	0.4	0.4	0.6	2.1	-1.2	0.6	0.9	0.4	0.5	0.5	0.7	0.5	0.5	0.7
Neuroticism (Nagel 2018)	0.3	0.6	3.4	-0.5	-0.5	-0.5	-1.8	0.4	-0.5	-0.3	-0.2	-0.7	-0.7	-1.2	-0.7	-0.7	-0.6
Alzheimer’s Disease (in father)	0.3	0.3	1.9	-0.4	-0.4	-0.3	1.4	-0.9	-0.3	-0.7	-0.4	-0.3	-0.3	-0.1	-0.4	-0.3	-0.3
Schizophrenia (2014)	0.3	0.6	2.2	0.4	0.7	0.5	-1.3	-0.2	0.5	1.2	-0.0	0.5	0.5	1.5	0.9	0.5	0.4
Blood White Count	0.3	2.0	4.9	-1.6	-1.3	-1.3	1.8	-0.5	-1.3	-2.2	-1.7	-1.3	-1.3	-0.5	-1.1	-1.3	-1.4
Hand grip strength (left)	0.3	0.8	3.0	-0.7	-1.0	-0.9	-0.8	-1.7	-0.9	0.3	-0.7	-0.8	-0.8	-0.8	-0.7	-0.8	-0.9
Trunk fat percentage	0.3	1.3	3.9	-0.9	-1.1	-0.9	-1.7	0.1	-0.9	-2.0	-0.8	-0.9	-0.9	-1.4	-1.2	-0.9	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	4.2	0.2	-0.3	0.2	-2.0	-0.3	0.2	1.2	0.1	0.2	0.2	0.2	0.2	0.2	0.0
Serious illness, injury or assault to yourself	0.3	0.4	0.6	-0.7	-0.8	-0.8	0.2	-0.1	-0.8	-0.0	-0.8	-0.7	-0.7	-0.0	-0.4	-0.7	-0.7
Stomach or abdominal pain in last month	0.3	0.4	2.3	-0.5	-0.4	-0.4	0.3	0.9	-0.4	-1.5	-0.4	-0.4	-0.4	-0.6	-0.5	-0.4	-0.5
Chronic bronchitis/emphysema (father)	0.3	0.4	1.4	0.8	0.6	0.4	1.2	1.2	0.4	-0.1	0.7	0.3	0.3	0.2	0.6	0.3	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	3.3	0.4	0.9	0.5	-0.7	1.8	0.5	0.2	0.7	0.5	0.5	-0.3	0.2	0.5	0.4
Hearing difficulty/problems with background noise	0.3	0.4	1.7	-0.6	-0.7	-0.6	-0.2	-0.1	-0.6	-0.4	-0.4	-0.6	-0.6	-1.3	-1.0	-0.6	-0.6
Had menopause	0.3	0.4	1.5	0.5	0.3	0.5	-0.2	1.2	0.5	0.5	0.4	0.5	0.5	0.8	0.5	0.5	0.7
Pain all over the body in last month	0.3	0.3	1.7	0.7	0.4	0.4	-0.5	-0.3	0.4	1.3	0.7	0.4	0.4	-0.1	0.4	0.4	0.3
Neuroticism score	0.3	0.7	2.2	-0.5	-0.7	-0.7	-1.5	0.5	-0.7	-0.9	-0.3	-0.8	-0.8	-1.1	-0.6	-0.8	-0.8
Happiness	0.3	0.4	3.4	0.2	0.0	0.1	-1.8	1.0	0.1	-0.7	0.4	0.1	0.1	-0.6	0.1	0.1	-0.2
Qualifications: A levels/AS levels or equivalent	0.3	0.6	3.2	-0.3	-0.7	-0.5	1.6	-1.8	-0.5	-0.9	-0.5	-0.6	-0.6	-0.0	-0.2	-0.6	-0.5
Lung cancer (father)	0.3	0.4	0.8	-0.6	-0.4	-0.7	-0.2	0.6	-0.7	-0.2	-0.9	-0.7	-0.7	-0.0	-0.4	-0.7	-0.8
Pulse wave Arterial Stiffness index	0.3	0.4	1.0	0.7	0.2	0.7	-1.0	0.4	0.7	-0.3	0.8	0.7	0.7	0.0	0.4	0.7	0.7
Length of working week for main job	0.3	0.3	3.3	0.3	-0.1	0.1	1.8	-0.7	0.1	-0.0	0.4	0.1	0.1	0.2	0.4	0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.7	0.4	0.3	0.2	1.4	0.7	0.2	-1.6	0.7	0.2	0.2	-0.2	0.4	0.2	0.2
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.3	-0.4	-0.6	-0.3	-1.0	-0.8	-0.3	1.1	-0.7	-0.3	-0.3	0.6	-0.0	-0.3	-0.3
Eye problems/disorders: None of the above	0.3	0.3	1.1	0.5	0.7	0.5	0.7	1.0	0.5	0.2	0.6	0.5	0.5	0.3	0.5	0.5	0.4
Medication: Aspirin	0.3	0.4	2.3	-0.5	-0.7	-0.3	0.2	0.7	-0.3	-0.9	0.1	-0.3	-0.3	-1.5	-1.0	-0.3	-0.3
Knee pain experienced in last month	0.3	0.5	3.6	0.4	0.8	0.3	-0.7	1.9	0.3	-0.7	0.5	0.3	0.3	-0.7	-0.1	0.3	0.1
Illnesses of siblings: Diabetes	0.3	0.4	2.4	0.5	0.2	0.3	-0.8	-0.5	0.3	1.5	0.3	0.3	0.3	0.8	0.7	0.3	0.3
Mineral and other dietary supplements	0.3	0.4	2.4	0.0	-0.2	0.2	1.0	-1.5	0.2	1.0	-0.2	0.2	0.2	1.0	0.5	0.2	0.1
Number of self-reported non-cancer illnesses	0.3	0.4	2.0	-0.3	-0.1	-0.2	-1.0	1.4	-0.2	-0.6	-0.1	-0.3	-0.3	-1.3	-0.7	-0.3	-0.5
Mother’s age at death	0.3	0.4	3.8	0.3	0.2	0.3	0.4	-2.0	0.3	0.8	0.2	0.3	0.3	0.4	0.4	0.3	0.3
Commuting to job workplace: Public transport	0.3	0.4	2.1	-0.5	-0.4	-0.4	0.0	-1.5	-0.4	0.3	-1.0	-0.4	-0.4	0.8	-0.0	-0.4	-0.3
Eye problems/disorders: Glaucoma	0.3	0.3	1.3	0.5	0.9	0.5	1.1	0.8	0.5	0.3	0.3	0.5	0.5	0.3	0.2	0.5	0.4
Medication: Atorvastatin	0.3	0.4	1.8	-0.3	-0.2	-0.3	-1.1	1.3	-0.3	-0.4	0.0	-0.3	-0.3	-1.2	-0.6	-0.3	-0.5
Irritability	0.3	0.5	1.4	0.8	0.8	0.7	-0.6	1.2	0.7	0.4	1.2	0.6	0.6	-0.2	0.6	0.6	0.7
Diastolic blood pressure, automated reading	0.3	1.0	2.9	0.9	0.7	1.0	1.7	1.4	1.0	-0.6	1.2	1.0	1.0	-0.0	0.6	1.0	0.8
Cholesterol lowering medication	0.3	0.5	0.7	0.8	0.3	0.8	-0.4	0.3	0.8	0.3	0.9	0.9	0.9	0.3	0.6	0.9	0.7
Worry (Nagel 2018)	0.2	0.4	1.9	-0.4	-0.2	-0.4	-0.3	0.8	-0.4	-0.7	-0.0	-0.5	-0.5	-1.4	-0.8	-0.5	-0.5
Reaction Time	0.2	0.4	2.4	0.2	1.0	0.4	0.6	1.5	0.4	0.2	0.1	0.4	0.4	1.0	0.7	0.4	0.3
Prostate Cancer	0.2	0.3	0.6	0.7	0.5	0.5	0.1	0.5	0.5	0.1	0.8	0.6	0.6	0.3	0.6	0.6	0.6
HbA1C	0.2	0.2	1.1	-0.3	-0.3	-0.3	0.7	-1.1	-0.3	0.6	-0.3	0.0	0.0	0.5	-0.1	0.0	0.2
LDL Cholesterol	0.2	0.3	0.9	0.3	1.0	0.7	0.2	0.9	0.7	-0.2	0.7	0.3	0.3	-0.4	0.1	0.3	0.4
Lupus	0.2	0.3	2.4	0.3	0.1	0.3	-1.5	-0.4	0.3	0.1	0.9	0.3	0.3	-0.9	-0.0	0.3	0.2
Neuroticism (2016)	0.2	0.2	0.9	0.7	0.5	0.5	-0.4	1.0	0.5	0.1	0.6	0.4	0.4	0.1	0.5	0.4	0.3
Cardiovascular Disease	0.2	0.7	4.8	-0.4	-0.3	-0.3	-1.1	2.2	-0.3	-0.6	0.1	-0.3	-0.3	-1.5	-0.7	-0.3	-0.5
Lung FVC	0.2	0.8	3.6	0.7	0.9	0.7	1.1	1.9	0.7	0.4	1.0	0.8	0.8	0.0	0.5	0.8	0.8
Sensitivity / hurt feelings	0.2	0.3	2.4	-0.0	0.0	-0.2	-1.6	1.1	-0.2	-0.2	0.1	-0.3	-0.3	-0.6	-0.2	-0.3	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.2	0.3	0.3	0.3	0.1	1.1	0.3	-0.6	0.5	0.3	0.3	-0.4	0.0	0.3	0.2
Vitamin and mineral supplements	0.2	0.3	1.3	-0.2	-0.3	-0.0	-0.9	-0.5	-0.0	-0.8	0.3	-0.0	-0.0	-1.2	-0.7	-0.0	-0.0
Diabetes (father)	0.2	0.2	0.8	0.5	0.1	0.4	0.5	-0.9	0.4	0.8	0.2	0.3	0.3	0.6	0.3	0.3	0.5
Diabetes (mother)	0.2	0.2	0.8	-0.5	-0.5	-0.4	-0.3	-0.1	-0.4	-0.9	-0.2	-0.4	-0.4	-0.8	-0.5	-0.4	-0.4
Taking other prescription medications	0.2	0.4	1.6	0.0	0.2	0.1	-0.8	1.2	0.1	-1.0	0.4	0.0	0.0	-1.3	-0.5	0.0	-0.1
High blood pressure (mother)	0.2	0.3	1.7	-0.3	-0.0	-0.2	-0.6	-0.0	-0.2	-1.3	-0.2	-0.2	-0.2	-1.0	-0.7	-0.2	-0.3
Number of incorrect matches in round	0.2	0.4	1.8	-0.6	-0.8	-0.6	0.5	-1.3	-0.6	-0.2	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5
Past tobacco smoking	0.2	0.3	2.1	-0.3	-0.6	-0.5	-0.3	-1.4	-0.5	0.2	-0.7	-0.4	-0.4	0.4	-0.2	-0.4	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	2.5	0.1	0.1	0.2	-1.6	-0.6	0.2	0.8	0.1	0.2	0.2	0.1	0.1	0.2	0.1
Financial difficulties in last 2 years	0.2	0.3	1.6	0.3	0.4	0.3	0.5	1.3	0.3	0.2	0.0	0.3	0.3	1.0	0.6	0.3	0.2
Diabetes (self-reported)	0.2	0.2	1.3	0.1	-0.7	-0.0	-1.1	-0.8	-0.0	0.5	0.3	-0.0	-0.0	-0.7	-0.3	-0.0	-0.0
Arm fat percentage (right)	0.2	0.7	5.7	-0.4	-0.7	-0.3	-2.4	0.3	-0.3	-1.3	-0.3	-0.4	-0.4	-0.7	-0.5	-0.4	-0.6
Alcohol intake versus 10 years previously	0.2	0.2	1.0	0.2	0.4	0.3	0.1	1.0	0.3	-0.9	0.6	0.4	0.4	-0.6	-0.0	0.4	0.2
Number of live births	0.2	0.3	0.9	-0.5	-0.3	-0.5	-0.4	0.8	-0.5	-1.0	-0.4	-0.4	-0.4	-0.5	-0.5	-0.4	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	1.9	-0.1	0.1	-0.1	1.4	0.0	-0.1	-1.2	0.1	-0.1	-0.1	-0.4	-0.1	-0.1	-0.1
Mouth/teeth dental problems: Dentures	0.2	0.3	1.3	0.3	-0.3	0.3	-0.3	0.7	0.3	-1.1	0.8	0.2	0.2	-1.2	-0.3	0.2	0.2
Asthma	0.2	0.3	1.0	-0.5	-0.5	-0.5	0.9	0.2	-0.5	-1.0	-0.6	-0.6	-0.6	-0.2	-0.4	-0.6	-0.6
Peak expiratory flow (PEF)	0.2	0.4	2.2	-0.2	-0.7	-0.3	0.3	0.2	-0.3	-1.2	0.4	-0.3	-0.3	-1.5	-0.7	-0.3	-0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	2.5	-0.2	-0.5	-0.4	-0.3	-1.6	-0.4	0.1	-0.6	-0.4	-0.4	0.5	0.1	-0.4	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.1	0.1	-0.1	-0.1	-0.7	-0.7	-0.1	1.1	-0.3	-0.1	-0.1	0.6	0.1	-0.1	-0.0
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.8	-0.6	-0.9	-0.5	0.6	-0.1	-0.5	-0.4	-0.4	-0.5	-0.5	-0.4	-0.5	-0.5	-0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.1	-0.5	-0.4	-0.4	-0.4	-1.0	-0.4	0.8	-0.9	-0.5	-0.5	0.8	-0.0	-0.5	-0.3
Neck or shoulder pain in last month	0.2	0.2	2.1	0.1	0.3	0.2	-0.1	1.4	0.2	-0.8	0.1	0.1	0.1	0.2	0.3	0.1	-0.0
Medication: Blood pressure	0.2	0.3	3.1	-0.2	0.0	-0.0	0.1	1.8	-0.0	-0.5	0.1	-0.0	-0.0	-0.8	-0.5	-0.0	-0.0
Migraine (self-reported)	0.2	0.3	1.1	0.4	0.3	0.5	1.1	0.9	0.5	-0.1	0.3	0.4	0.4	0.6	0.5	0.4	0.4
Chest pain or discomfort	0.2	0.3	1.0	-0.4	-0.5	-0.5	1.0	0.8	-0.5	-0.4	-0.6	-0.5	-0.5	-0.3	-0.5	-0.5	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.5	-0.4	-0.2	-0.5	-0.6	0.7	-0.5	-0.6	-0.2	-0.6	-0.6	-0.7	-0.3	-0.6	-0.7
Supplements: Vitamin C	0.2	0.2	1.0	0.1	0.5	0.3	1.0	0.0	0.3	0.7	0.2	0.3	0.3	0.4	0.3	0.3	0.3
Arm fat percentage (left)	0.2	0.8	5.1	-0.5	-0.8	-0.5	-2.3	0.3	-0.5	-1.5	-0.4	-0.5	-0.5	-0.9	-0.7	-0.5	-0.7
Long-standing illness, disability or infirmity	0.2	0.3	0.8	0.5	0.5	0.5	-0.8	0.9	0.5	0.6	0.4	0.4	0.4	0.4	0.4	0.4	0.3
Friendships satisfaction	0.2	0.3	1.8	0.6	0.5	0.2	-0.5	1.3	0.2	-0.1	0.5	0.2	0.2	0.3	0.7	0.2	0.2
Asthma (self-reported)	0.2	0.4	1.1	-0.6	-0.6	-0.6	0.8	0.1	-0.6	-1.0	-0.7	-0.7	-0.7	-0.3	-0.5	-0.7	-0.7
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.3	0.4	0.4	0.3	-0.5	0.9	0.3	-1.1	0.5	0.3	0.3	-0.4	-0.0	0.3	0.3
Illnesses of father: High blood pressure	0.2	0.3	1.6	-0.5	-0.8	-0.4	-1.3	-0.1	-0.4	0.3	-0.5	-0.4	-0.4	-0.3	-0.3	-0.4	-0.5
Ever smoked	0.2	0.3	1.6	0.1	0.6	0.4	0.5	1.2	0.4	-0.3	0.6	0.4	0.4	-0.5	0.1	0.4	0.3
Bipolar Disorder or Schizophrenia	0.1	0.3	1.6	-0.0	0.1	-0.2	-1.1	-0.4	-0.2	1.3	-0.5	-0.2	-0.2	1.0	0.5	-0.2	-0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.9	0.0	0.0	0.0	0.3	0.9	0.0	-1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.1	0.2	1.0	-0.3	-0.3	-0.2	-0.7	-0.5	-0.2	1.0	-0.3	-0.2	-0.2	0.0	-0.2	-0.2	-0.2
Smoking Status	0.1	0.2	0.5	0.4	0.4	0.5	0.7	-0.1	0.5	0.1	0.6	0.5	0.5	-0.0	0.4	0.5	0.3
Respiratory disease	0.1	0.2	1.4	0.1	0.0	0.2	1.2	0.6	0.2	-0.8	0.1	0.1	0.1	0.1	0.1	0.1	0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.3	1.8	0.1	-0.6	0.2	-0.6	-1.3	0.2	1.0	0.2	0.2	0.2	-0.0	-0.0	0.2	0.2
Neuroticism	0.1	0.2	1.2	0.0	0.1	-0.0	-1.1	0.5	-0.0	0.1	0.3	-0.1	-0.1	-0.7	-0.2	-0.1	-0.0
Hair Pigment	0.1	2.1	4.8	1.5	1.2	1.6	1.2	-0.5	1.6	0.4	1.1	1.6	1.6	2.2	1.9	1.6	1.4
Frequency of depressed mood in last 2 weeks	0.1	0.2	2.0	0.0	-0.3	-0.0	-1.4	-0.3	-0.0	0.6	-0.0	-0.0	-0.0	-0.4	-0.2	-0.0	-0.3
Relative age of first facial hair	0.1	0.2	1.4	-0.2	-0.6	-0.3	-0.3	-1.2	-0.3	0.2	-0.2	-0.3	-0.3	-0.3	-0.2	-0.3	-0.3
Ever had hysterectomy (womb removed)	0.1	0.1	0.4	-0.0	-0.3	0.0	-0.2	-0.2	0.0	0.6	0.2	0.1	0.1	-0.3	-0.2	0.1	0.2
Medication for hormone replacement therapy	0.1	0.1	0.5	0.2	0.1	0.2	0.7	0.4	0.2	-0.0	0.2	0.2	0.2	0.4	0.4	0.2	0.2
Townsend deprivation index at recruitment	0.1	0.1	0.6	0.0	0.3	0.3	0.2	0.8	0.3	0.4	0.1	0.3	0.3	0.4	0.3	0.3	0.2
Fed-up feelings	0.1	0.3	2.7	-0.1	-0.2	0.0	-1.6	0.6	0.0	0.3	0.2	-0.2	-0.2	-0.4	0.0	-0.2	-0.2
Relative age voice broke	0.1	0.1	0.7	-0.2	0.1	0.0	0.3	-0.8	0.0	0.6	-0.2	0.0	0.0	0.1	-0.1	0.0	0.0
Multivitamins +/- minerals	0.1	0.2	0.4	-0.3	-0.3	-0.5	-0.2	0.5	-0.5	0.1	-0.6	-0.5	-0.5	0.4	0.1	-0.5	-0.6
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.9	-0.3	0.1	-0.2	-0.9	0.9	-0.2	-0.5	-0.2	-0.2	-0.2	-0.3	-0.4	-0.2	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.4	0.3	0.6	0.5	-0.1	0.5	0.5	0.6	0.3	0.5	0.5	0.5	0.4	0.5	0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.7	-0.1	0.4	-0.1	0.1	0.4	-0.1	0.8	-0.2	-0.1	-0.1	0.6	0.3	-0.1	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.4	0.3	0.1	0.0	0.7	0.0	0.0	-0.4	-0.0	0.1	0.1	0.5	0.4	0.1	-0.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.5	-0.0	0.1	0.0	-0.7	0.7	0.0	-0.2	-0.1	0.0	0.0	0.3	0.3	0.0	-0.2
Headache pain in last month	0.1	0.3	1.1	0.7	0.6	0.5	-0.3	1.0	0.5	-0.1	0.4	0.5	0.5	0.2	0.4	0.5	0.3
Medication: Amlodipine	0.1	0.1	0.2	0.2	0.2	0.2	-0.4	0.5	0.2	0.5	0.2	0.3	0.3	-0.1	-0.0	0.3	0.2
Comparative body size at age 10	0.1	0.3	0.8	-0.3	-0.6	-0.5	-0.2	-0.9	-0.5	0.6	-0.8	-0.5	-0.5	0.8	0.1	-0.5	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	-0.5	0.0	-0.3	-0.5	-0.0	-0.3	-0.3	-0.3	-0.3	-0.3	-0.5	-0.4	-0.3	-0.5
Shortness of breath walking on level ground	0.1	0.1	0.7	-0.2	0.2	0.2	0.7	0.8	0.2	-0.1	-0.3	0.2	0.2	0.0	-0.3	0.2	0.1
Medication: Ibuprofen	0.1	0.1	0.2	0.4	0.2	0.1	0.3	0.5	0.1	-0.3	0.0	0.1	0.1	0.5	0.4	0.1	-0.1
Medication: Seretide 50 evohaler	0.1	0.1	1.2	-0.3	-0.4	-0.2	-0.0	-1.1	-0.2	0.3	-0.3	-0.3	-0.3	-0.1	-0.2	-0.3	-0.2
Suffer from ‘nerves’	0.1	0.2	0.7	-0.4	-0.5	-0.3	-0.0	0.3	-0.3	-0.5	-0.3	-0.3	-0.3	-0.8	-0.6	-0.3	-0.4
Smoking status: Previous	0.1	0.2	1.8	-0.2	0.1	-0.1	-0.3	1.3	-0.1	-0.7	0.1	-0.1	-0.1	-0.6	-0.2	-0.1	-0.2
Mood swings	0.1	0.1	0.9	0.2	0.2	0.1	-1.0	0.0	0.1	0.6	0.2	-0.1	-0.1	-0.2	0.1	-0.1	-0.1
Diabetes diagnosed by doctor	0.1	0.2	1.6	0.4	-0.2	0.4	-0.6	-0.8	0.4	1.2	0.4	0.3	0.3	-0.1	0.1	0.3	0.3
Qualifications: nursing, teaching	0.1	0.2	1.0	-0.1	-0.5	-0.3	0.1	-1.0	-0.3	-0.2	-0.3	-0.3	-0.3	0.6	0.3	-0.3	-0.2
Eye problems/disorders: Cataract	0.1	0.1	0.5	-0.2	-0.1	-0.2	-0.4	-0.0	-0.2	-0.7	-0.4	-0.2	-0.2	0.1	-0.2	-0.2	-0.1
Back pain experienced in last month	0.1	0.2	1.5	-0.1	-0.1	-0.2	-1.2	0.3	-0.2	-0.8	0.0	-0.2	-0.2	-0.3	-0.1	-0.2	-0.3
Osteoarthritis (self-reported)	0.1	0.1	0.3	-0.4	0.1	-0.2	-0.4	0.6	-0.2	-0.0	-0.3	-0.3	-0.3	-0.3	-0.4	-0.3	-0.2
Medication: Aspirin	0.1	0.2	0.9	-0.1	-0.3	0.1	0.1	0.9	0.1	-0.5	0.4	0.1	0.1	-1.0	-0.5	0.1	0.1
Medication: Gliclazide	0.1	0.1	0.4	-0.2	-0.6	-0.1	0.3	0.2	-0.1	-0.3	0.0	-0.1	-0.1	-0.5	-0.4	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.4	0.2	0.0	0.1	-0.9	0.9	0.1	-1.2	0.4	0.1	0.1	-0.7	-0.2	0.1	0.2
Medication: Paracetamol	0.1	0.1	0.5	0.4	0.3	0.2	0.6	0.7	0.2	-0.4	0.5	0.2	0.2	-0.2	0.2	0.2	0.2
Fractured/broken bones in last 5 years	0.1	0.1	0.9	-0.2	-0.2	-0.1	-0.8	-1.0	-0.1	-0.1	-0.1	-0.0	-0.0	-0.4	-0.5	-0.0	0.0
Supplements: Calcium	0.1	0.1	0.4	0.2	0.3	0.0	0.3	0.6	0.0	0.4	-0.1	0.0	0.0	0.3	0.1	0.0	0.0
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.3	0.5	0.2	0.4	0.6	0.5	0.4	0.3	0.4	0.5	0.5	0.4	0.5	0.5	0.4
Bipolar Disorder (2011)	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.2	1.5	0.2	0.1	0.3	0.3	1.2	0.3	-0.2	0.4	0.1	0.1	0.0	0.3	0.1	0.2
Chronotype (morning person)	0.0	0.1	0.2	0.2	-0.2	-0.3	-0.4	0.1	-0.3	-0.2	-0.0	-0.1	-0.1	-0.4	-0.2	-0.1	-0.3
Tanning	0.0	0.5	1.9	-0.5	-0.0	-0.6	1.4	1.1	-0.6	-0.6	-0.5	-0.6	-0.6	-0.8	-0.8	-0.6	-0.5
Other serious medical condition/disability diagnosed by doctor	0.0	0.1	0.2	0.3	-0.2	0.2	-0.3	-0.1	0.2	-0.4	0.2	0.2	0.2	0.2	0.3	0.2	0.1
Medication: Metformin	0.0	0.1	0.3	0.1	-0.3	0.1	-0.6	-0.1	0.1	0.2	0.2	0.1	0.1	-0.3	-0.2	0.1	0.2
Average weekly fortified wine intake	0.0	0.1	0.2	0.1	0.2	0.3	-0.5	0.1	0.3	0.0	0.2	0.3	0.3	0.0	-0.0	0.3	0.3
Heart attack	0.0	0.0	0.1	0.2	-0.1	0.2	0.1	0.3	0.2	0.2	0.2	0.2	0.2	0.1	0.3	0.2	0.1
Medication: Paracetamol	0.0	0.1	0.4	0.2	0.1	0.1	0.2	0.1	0.1	-0.6	0.4	0.1	0.1	-0.6	-0.0	0.1	-0.0
Glaucoma (self-reported)	0.0	0.1	0.2	0.3	0.5	0.1	0.3	0.2	0.1	0.2	-0.1	0.1	0.1	0.4	0.2	0.1	0.0
Emphysema/chronic bronchitis	0.0	0.0	0.3	-0.1	0.0	-0.0	-0.6	0.1	-0.0	0.2	-0.0	-0.1	-0.1	-0.4	-0.3	-0.1	-0.0

Hub : Genes

TMEM173

Models

Trait associations