Best TWAS P=1.26e-10 · Best GWAS P=9.99e-42 conditioned to 1.53e-27
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | U91328.21 | 0.18 | 0.00 | lasso | 11 | 0.02 | 3.5e-02 | -0.7 | 5.2 | 2.1e-07 | -0.08 | 0.18 | 0.03 | TRUE |
| 2 | GTEx | Artery Tibial | TRIM38 | 0.08 | 0.00 | lasso | 9 | 0.00 | 3.7e-01 | 5.0 | 6.0 | 1.4e-09 | -0.25 | 0.30 | 0.04 | FALSE |
| 3 | GTEx | Artery Tibial | U91328.21 | 0.09 | 0.01 | lasso | 8 | 0.01 | 3.0e-02 | 3.3 | 6.4 | 1.3e-10 | -0.15 | 0.28 | 0.15 | TRUE |
| 4 | GTEx | Whole Blood | TRIM38 | 0.08 | 0.04 | enet | 13 | 0.03 | 1.4e-03 | 4.3 | 5.3 | 1.2e-07 | -0.28 | 0.79 | 0.01 | FALSE |
| 5 | METSIM | Adipose | U91328.20 | 0.07 | 0.04 | bslmm | 658 | 0.04 | 8.9e-07 | -2.6 | 5.9 | 4.2e-09 | -0.43 | 0.93 | 0.03 | TRUE |