[Hub]/) : Traits : Comparative height size at age 10 :

chr6:33,662,667-36,158,878

Best TWAS P=2.2e-38 · Best GWAS P=9.1e-50 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C6orf106 0.29 0.21 bslmm 382 0.23 6.9e-28 10.67 9.7 4.6e-22 -0.07 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex FANCE 0.03 0.02 bslmm 420 0.01 1.7e-02 -7.60 -10.6 3.1e-26 0.08 0.27 0.30 FALSE
3 CommonMind Brain Pre-frontal Cortex PACSIN1 0.07 0.01 lasso 6 0.02 1.1e-03 11.06 9.3 1.5e-20 0.16 0.33 0.03 FALSE
4 CommonMind Brain Pre-frontal Cortex RPL10A 0.21 0.09 enet 30 0.11 2.6e-13 -6.44 -5.4 6.0e-08 -0.01 1.00 0.00 TRUE
5 GTEx Adipose Subcutaneous RPL10A 0.06 0.02 enet 27 0.03 2.6e-03 -6.62 -6.1 9.1e-10 -0.10 0.32 0.04 FALSE
6 GTEx Artery Aorta RPL10A 0.20 0.12 lasso 5 0.11 8.8e-07 -6.43 -6.8 1.3e-11 -0.04 0.96 0.00 FALSE
7 GTEx Artery Tibial C6orf106 0.07 0.02 lasso 4 0.02 8.8e-03 -6.21 8.3 7.5e-17 -0.13 0.10 0.05 FALSE
8 GTEx Artery Tibial RPL10A 0.11 0.08 lasso 2 0.09 1.5e-07 -6.12 -6.5 9.1e-11 -0.08 1.00 0.00 FALSE
9 GTEx Brain Cerebellum PPARD 0.37 0.06 lasso 18 0.13 9.3e-05 1.34 -6.2 4.4e-10 0.05 0.14 0.05 FALSE
10 GTEx Brain Cortex C6orf106 0.22 0.07 enet 16 0.10 1.1e-03 11.04 10.7 7.0e-27 0.26 0.51 0.03 FALSE
11 GTEx Brain Frontal Cortex BA9 TAF11 0.25 0.01 lasso 10 0.00 2.7e-01 -5.13 -5.3 1.3e-07 0.00 0.07 0.06 FALSE
12 GTEx Brain Frontal Cortex BA9 RPS10 0.21 0.08 lasso 3 0.06 8.6e-03 3.64 5.3 9.3e-08 -0.05 0.12 0.05 FALSE
13 GTEx Cells EBV-transformed lymphocytes C6orf106 0.20 0.00 lasso 5 0.00 2.7e-01 7.43 5.9 2.8e-09 0.08 0.07 0.05 FALSE
14 GTEx Cells Transformed fibroblasts TEAD3 0.36 0.29 enet 27 0.32 8.4e-25 3.35 -5.8 8.1e-09 -0.09 1.00 0.00 FALSE
15 GTEx Cells Transformed fibroblasts NUDT3 0.11 0.03 lasso 3 0.02 9.2e-03 6.36 -5.8 5.0e-09 -0.40 0.24 0.03 TRUE
16 GTEx Colon Transverse C6orf106 0.15 0.05 lasso 1 0.03 1.5e-02 8.07 8.1 7.3e-16 -0.03 0.17 0.04 FALSE
17 GTEx Colon Transverse RPL10A 0.12 0.05 lasso 4 0.05 2.5e-03 -6.12 -6.9 4.8e-12 -0.06 0.26 0.12 FALSE
18 GTEx Esophagus Mucosa RPL10A 0.14 0.10 enet 17 0.09 2.1e-06 -6.12 -8.8 1.9e-18 -0.12 0.93 0.02 TRUE
19 GTEx Esophagus Muscularis RPL10A 0.31 0.19 lasso 5 0.18 4.6e-11 -6.43 -6.3 2.6e-10 -0.01 1.00 0.00 FALSE
20 GTEx Heart Atrial Appendage TEAD3 0.17 0.08 lasso 6 0.09 1.1e-04 4.54 -5.2 2.4e-07 0.01 0.56 0.03 FALSE
21 GTEx Muscle Skeletal C6orf106 0.08 0.06 lasso 4 0.06 7.1e-07 4.81 -5.5 5.0e-08 -0.10 0.98 0.00 FALSE
22 GTEx Nerve Tibial DEF6 0.15 0.00 lasso 8 0.00 1.6e-01 -6.41 8.0 1.2e-15 -0.01 0.18 0.05 FALSE
23 GTEx Nerve Tibial C6orf106 0.11 0.07 enet 17 0.07 1.3e-05 11.21 11.8 4.9e-32 0.03 0.71 0.01 FALSE
24 GTEx Nerve Tibial RPL10A 0.14 0.12 lasso 3 0.12 9.7e-09 -6.43 -5.8 7.5e-09 -0.01 1.00 0.00 FALSE
25 GTEx Pancreas C6orf106 0.14 0.11 enet 11 0.13 2.8e-06 4.76 9.2 4.9e-20 0.10 0.86 0.01 FALSE
26 GTEx Skin Not Sun Exposed Suprapubic TEAD3 0.15 0.06 lasso 5 0.08 2.5e-05 -6.16 -7.5 7.4e-14 -0.09 0.39 0.51 FALSE
27 GTEx Skin Not Sun Exposed Suprapubic SNRPC 0.18 0.04 enet 37 0.03 1.0e-02 0.64 5.8 7.2e-09 -0.04 0.25 0.03 FALSE
28 GTEx Skin Sun Exposed Lower leg C6orf106 0.09 0.04 enet 25 0.02 4.6e-03 -5.59 9.6 6.8e-22 0.04 0.38 0.02 FALSE
29 GTEx Testis ZNF76 0.15 0.14 enet 8 0.12 4.4e-06 -6.43 6.9 5.0e-12 -0.02 0.94 0.01 FALSE
30 GTEx Thyroid C6orf106 0.09 0.01 enet 29 0.01 1.1e-01 11.06 7.3 3.0e-13 -0.10 0.10 0.03 TRUE
31 GTEx Thyroid RPL10A 0.16 0.09 lasso 11 0.07 8.9e-06 -6.08 -6.1 8.2e-10 -0.13 0.89 0.01 FALSE
32 GTEx Whole Blood DEF6 0.14 0.05 lasso 4 0.03 9.9e-04 -6.54 6.4 1.5e-10 -0.14 0.87 0.00 FALSE
33 METSIM Adipose C6orf106 0.04 0.02 blup 381 0.02 7.7e-04 5.29 5.2 1.8e-07 -0.13 0.43 0.02 FALSE
34 METSIM Adipose RPL10A 0.18 0.13 lasso 15 0.13 3.4e-19 -6.43 -5.8 5.1e-09 0.00 1.00 0.00 FALSE
35 NTR Blood C6orf106 0.03 0.02 lasso 6 0.02 7.2e-07 11.00 11.8 4.3e-32 0.05 1.00 0.00 FALSE
36 NTR Blood ZNF76 0.01 0.00 blup 424 0.00 3.8e-02 -4.77 7.9 2.5e-15 -0.17 0.24 0.02 FALSE
37 ROSMAP Brain Pre-frontal Cortex DEF6 0.04 0.02 bslmm 421 0.02 1.8e-03 -7.70 6.5 6.9e-11 -0.18 0.78 0.04 FALSE
38 ROSMAP Brain Pre-frontal Cortex ZNF76 0.04 0.00 blup 424 0.02 2.1e-03 -6.40 5.7 1.4e-08 -0.22 0.53 0.02 FALSE
39 ROSMAP Brain Pre-frontal Cortex PACSIN1 0.09 0.00 blup 359 0.02 4.5e-04 10.67 10.5 5.4e-26 0.27 0.18 0.07 FALSE
40 ROSMAP Brain Pre-frontal Cortex C6orf106 0.30 0.26 bslmm 372 0.33 9.3e-44 11.00 12.3 1.6e-34 0.00 1.00 0.00 FALSE
41 YFS Blood ZNF76 0.05 0.08 lasso 4 0.07 6.7e-23 -6.52 6.4 1.9e-10 -0.17 1.00 0.00 FALSE
42 The Cancer Genome Atlas Bladder Urothelial Carcinoma RPL10A 0.03 0.00 blup 54 0.02 6.0e-03 -7.79 -8.1 8.2e-16 0.03 0.01 0.85 FALSE
43 The Cancer Genome Atlas Breast Invasive Carcinoma TCP11 0.03 0.03 blup 49 0.04 6.6e-08 -4.29 -7.8 7.6e-15 0.07 0.70 0.30 FALSE
44 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TCP11 0.07 0.01 enet 8 0.01 8.2e-02 -7.81 -7.5 9.1e-14 -0.02 0.06 0.31 FALSE
45 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C6orf106 0.09 0.03 lasso 5 0.05 3.6e-06 -4.03 7.1 1.6e-12 -0.03 0.32 0.05 FALSE
46 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TCP11 0.03 0.00 blup 49 0.01 8.8e-03 -7.29 -7.3 2.8e-13 0.02 0.10 0.07 TRUE
47 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C6orf106 0.04 0.01 blup 68 0.01 2.4e-02 10.96 11.0 5.2e-28 0.08 0.01 0.81 FALSE
48 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPL10A 0.07 0.07 lasso 2 0.06 9.9e-08 -6.12 -6.6 3.9e-11 -0.04 1.00 0.00 TRUE
49 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TCP11 0.03 0.02 blup 49 0.02 1.7e-03 -3.99 -7.6 2.4e-14 0.07 0.02 0.95 FALSE
50 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PPARD 0.07 0.06 lasso 3 0.04 2.5e-03 -7.26 -6.7 3.0e-11 0.17 0.12 0.36 FALSE
51 The Cancer Genome Atlas Brain Lower Grade Glioma C6orf106 0.04 0.05 lasso 4 0.03 8.1e-05 10.99 10.7 1.2e-26 0.09 0.02 0.98 FALSE
52 The Cancer Genome Atlas Brain Lower Grade Glioma TCP11 0.05 0.04 blup 49 0.06 1.3e-07 -7.29 -7.2 6.3e-13 0.05 0.09 0.91 FALSE
53 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ZNF76 0.08 0.05 lasso 10 0.07 4.9e-04 -8.92 -7.0 3.0e-12 0.06 0.05 0.35 FALSE
54 The Cancer Genome Atlas Lung Adenocarcinoma C6orf106 0.03 0.03 lasso 3 0.01 7.6e-03 5.29 7.3 2.6e-13 0.00 0.02 0.82 FALSE
55 The Cancer Genome Atlas Lung Adenocarcinoma RPL10A 0.02 0.02 lasso 2 0.02 3.8e-03 -6.94 -6.9 4.0e-12 -0.01 0.08 0.04 FALSE
56 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TCP11 0.03 0.03 blup 49 0.03 3.5e-04 -7.29 -7.8 4.5e-15 0.05 0.07 0.81 FALSE
57 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C6orf106 0.14 0.07 enet 6 0.06 1.0e-04 11.00 11.1 1.2e-28 0.08 0.01 0.97 TRUE
58 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TCP11 0.05 0.07 lasso 2 0.07 1.9e-05 -7.13 -7.2 6.1e-13 0.01 0.15 0.71 FALSE
59 The Cancer Genome Atlas Pancreatic Adenocarcinoma TCP11 0.08 0.11 lasso 2 0.11 3.4e-05 -7.13 -7.2 5.3e-13 0.01 0.11 0.57 FALSE
60 The Cancer Genome Atlas Prostate Adenocarcinoma RPL10A 0.09 0.03 enet 19 0.07 1.1e-07 -6.43 -8.5 1.9e-17 0.01 0.91 0.04 FALSE
61 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF76 0.03 0.02 lasso 3 0.02 3.5e-03 -7.03 6.4 1.5e-10 -0.06 0.21 0.34 TRUE
62 The Cancer Genome Atlas Thyroid Carcinoma C6orf106 0.08 0.00 enet 15 0.05 2.5e-05 -6.06 13.0 2.2e-38 -0.05 0.03 0.29 TRUE
63 The Cancer Genome Atlas Thyroid Carcinoma RPL10A 0.05 0.07 enet 4 0.04 1.2e-04 -6.43 -7.3 3.3e-13 -0.03 0.76 0.05 FALSE
64 The Cancer Genome Atlas Thyroid Carcinoma TCP11 0.03 0.02 blup 49 0.02 1.6e-03 -7.13 -7.8 5.5e-15 0.04 0.02 0.82 FALSE