Best TWAS P=9.97e-14 · Best GWAS P=1.41e-13 conditioned to 0.0798
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TCF4 | 0.06 | 0.00 | enet | 4 | 0.00 | 5.1e-01 | 7.4 | -7.4 | 1.0e-13 | -0.88 | 0.02 | 0.93 | TRUE |
| 2 | YFS | Blood | TCF4 | 0.03 | 0.01 | enet | 27 | 0.02 | 3.4e-06 | 6.2 | -5.5 | 4.8e-08 | -0.46 | 0.21 | 0.67 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | TCF4 | 0.04 | 0.06 | lasso | 2 | 0.06 | 1.9e-07 | 7.3 | -6.9 | 3.8e-12 | -0.95 | 0.00 | 1.00 | FALSE |