[Hub]/) : Traits : Mood swings : ←

chr22:40,472,399-42,614,362

Best TWAS P=3.02e-11 · Best GWAS P=2.52e-12 conditioned to 0.0198

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex XPNPEP3 0.06 0.04 lasso 4 0.04 3.9e-06 -3.7 5.2 2.1e-07 0.68 0.25 0.75 FALSE
2 GTEx Artery Aorta L3MBTL2 0.14 0.01 lasso 6 0.04 1.8e-03 -4.8 5.7 1.6e-08 0.73 0.03 0.91 FALSE
3 GTEx Cells Transformed fibroblasts SLC25A17 0.09 0.03 enet 10 0.06 4.2e-05 6.7 6.6 3.0e-11 0.90 0.01 0.98 TRUE
4 GTEx Esophagus Mucosa RANGAP1 0.07 0.02 lasso 4 0.02 8.6e-03 6.1 -6.0 1.5e-09 -0.88 0.04 0.87 FALSE
5 GTEx Nerve Tibial ACO2 0.06 0.05 lasso 5 0.04 8.5e-04 4.9 5.5 3.3e-08 0.69 0.82 0.07 FALSE
6 GTEx Testis TEF 0.06 0.05 lasso 5 0.04 5.5e-03 5.3 5.3 9.8e-08 0.63 0.40 0.06 FALSE
7 GTEx Thyroid ACO2 0.08 0.09 lasso 6 0.10 9.6e-08 5.4 5.2 1.7e-07 0.65 0.98 0.02 FALSE
8 NTR Blood TEF 0.01 0.02 lasso 2 0.02 3.8e-06 5.2 5.4 8.6e-08 0.63 0.95 0.04 FALSE
9 YFS Blood TEF 0.09 0.17 lasso 2 0.17 9.0e-53 5.4 5.4 7.7e-08 0.64 0.99 0.01 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma TEF 0.04 0.03 blup 36 0.03 9.5e-03 4.9 5.5 4.0e-08 0.64 0.02 0.86 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TOB2 0.03 0.00 blup 28 0.02 3.4e-03 4.9 5.2 2.0e-07 0.68 0.02 0.43 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma RANGAP1 0.19 0.04 enet 10 0.05 2.8e-04 6.7 5.4 7.4e-08 0.80 0.00 0.92 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma L3MBTL2 0.05 0.03 enet 9 0.04 1.8e-04 6.7 6.2 4.5e-10 0.88 0.01 0.97 FALSE