Best TWAS P=4.39e-10 · Best GWAS P=7.79e-09 conditioned to 0.714
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | PTK2 | 0.28 | 0.01 | lasso | 4 | 0.09 | 0.00151 | -5.3 | 5.4 | 8.1e-08 | -0.51 | 0.09 | 0.62 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | PTK2 | 0.05 | 0.03 | lasso | 5 | 0.03 | 0.00075 | -5.8 | 6.2 | 4.4e-10 | -0.94 | 0.01 | 0.98 | TRUE |