Best TWAS P=1.48e-08 · Best GWAS P=4.43e-11 conditioned to 0.000741
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MMP16 | 0.12 | 0.07 | lasso | 4 | 0.08 | 4.3e-09 | 6.1 | 5.1 | 2.9e-07 | 0.80 | 0 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MMP16 | 0.10 | 0.08 | blup | 131 | 0.05 | 1.3e-03 | 6.0 | 5.2 | 1.6e-07 | 0.77 | 0 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | MMP16 | 0.10 | 0.09 | lasso | 4 | 0.08 | 2.9e-08 | 6.1 | 5.7 | 1.5e-08 | 0.86 | 0 | 1.00 | TRUE |