Hub : Traits :

Irritability

628 significantly associated models · 84 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	2	43899918	45698128	1	1	8.9e-08	3.3e-08	1.0e-01	91	CAMKMT
2	3	48350366	50144951	8	1	2.7e-09	6.1e-09	1.0e+00	100	CCDC36
3	5	49462228	50836718	2	1	6.4e-08	9.3e-07	1.2e-01	90	PARP8
4	5	87104604	88677293	1	1	3.7e-08	6.8e-10	5.3e-03	80	LINC00461
5	7	11553163	12967449	1	1	1.7e-07	6.0e-08	1.4e-01	93	TMEM106B
6	8	8092025	13120332	35	1	6.9e-17	1.0e-17	6.5e-05	78	AF131215.9
7	8	88801153	89582625	1	1	1.5e-08	4.4e-11	7.4e-04	74	MMP16
8	12	15807367	17456908	1	1	7.8e-08	4.6e-05	3.6e-02	74	MGST1
9	13	110831451	112257226	1	1	1.5e-07	4.6e-06	1.0e+00	100	ANKRD10
10	16	30347731	31758245	6	1	3.6e-10	3.8e-10	2.3e-01	96	HSD3B7
11	16	70624483	72022941	2	1	2.9e-08	7.9e-08	1.3e-01	92	CMTR2
12	17	42774693	45796313	18	1	1.3e-11	1.4e-09	3.5e-01	98	WNT3
13	20	32254831	34109427	4	1	2.1e-13	7.1e-12	8.3e-01	100	TP53INP2
14	22	40472399	42379813	2	1	9.1e-08	7.0e-09	2.5e-02	85	SLC25A17

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder (2018)	1.78	1	0	0.0	0.00	1.0e+00	TP53INP2
Bipolar Disorder or Schizophrenia	2.65	1	1	2.2	0.00	1.0e+00	SLC25A17
Depressed Affect (Nagel 2018)	10.45	7	4	8.9	0.99	4.7e-05	CCDC36 CMTR2 HSD3B7 LINC00461 PARP8 TMEM106B WNT3
Depression (Nagel 2018)	5.18	3	1	2.2	0.00	1.0e+00	CMTR2 TMEM106B WNT3
Intelligence (Savage-Jansen 2018)	2.49	2	2	4.4	0.00	1.0e+00	LINC00461 WNT3
Neuroticism (Nagel 2018)	13.35	9	6	13.3	0.98	2.5e-06	ANKRD10 CMTR2 HSD3B7 LINC00461 PARP8 SLC25A17 TMEM106B TP53INP2 WNT3
Schizophrenia (2018)	2.69	1	0	0.0	0.00	1.0e+00	SLC25A17
Worry (Nagel 2018)	7.57	5	2	4.4	0.99	9.1e-04	HSD3B7 SLC25A17 TMEM106B TP53INP2 WNT3
Major Depression (MDD)	2.92	1	0	0.0	0.00	1.0e+00	TMEM106B
Verbal and Numeric Reasoning (VNR)	2.19	1	0	0.0	0.00	1.0e+00	LINC00461
Breast Cancer	2.31	1	1	2.2	0.00	1.0e+00	WNT3
Ovarian Cancer	2.35	1	1	2.2	0.00	1.0e+00	WNT3
Mean Putamen Volume	2.88	1	0	0.0	0.00	1.0e+00	WNT3
LDL Cholesterol	1.61	1	0	0.0	0.00	1.0e+00	CMTR2
Lupus	2.00	1	0	0.0	0.00	1.0e+00	AF131215.9
Neuroticism (2016)	9.55	4	2	4.4	1.00	1.5e-03	AF131215.9 LINC00461 SLC25A17 WNT3
Primary Biliary Cirrhosis	2.13	1	0	0.0	0.00	1.0e+00	WNT3
Schizophrenia (2014)	2.58	1	0	0.0	0.00	1.0e+00	SLC25A17
Triglycerides	2.98	1	0	0.0	0.00	1.0e+00	TP53INP2
Blood Eosinophil Count	2.07	3	3	6.7	0.00	1.0e+00	CCDC36 SLC25A17 WNT3
Blood Platelet Count	0.59	2	1	2.2	0.00	1.0e+00	LINC00461 WNT3
Blood Red Count	5.53	5	3	6.7	0.81	9.8e-02	ANKRD10 CMTR2 HSD3B7 LINC00461 WNT3
Blood White Count	0.55	2	0	0.0	0.00	1.0e+00	LINC00461 WNT3
Heel T-Score	2.43	4	3	6.7	-0.78	2.2e-01	CCDC36 MMP16 SLC25A17 WNT3
BMI	2.89	3	1	2.2	0.00	1.0e+00	HSD3B7 LINC00461 MMP16
Height	2.02	5	5	11.1	-0.79	1.1e-01	CAMKMT CMTR2 TMEM106B TP53INP2 WNT3
Waist Hip Ratio (WHR)	2.85	2	2	4.4	0.00	1.0e+00	MMP16 WNT3
Systolic Blood Pressure	0.96	1	0	0.0	0.00	1.0e+00	CMTR2
Smoking Status	2.52	2	0	0.0	0.00	1.0e+00	CCDC36 WNT3
Allergy or Eczema	1.62	1	1	2.2	0.00	1.0e+00	SLC25A17
Lung FEV1/FVC ratio	1.33	1	0	0.0	0.00	1.0e+00	MMP16
Lung FVC	5.19	3	3	6.7	0.00	1.0e+00	HSD3B7 TP53INP2 WNT3
Neuroticism	11.33	8	5	11.1	0.98	2.4e-05	CMTR2 HSD3B7 LINC00461 PARP8 SLC25A17 TMEM106B TP53INP2 WNT3
Hair Pigment	8.85	3	2	4.4	0.00	1.0e+00	SLC25A17 TP53INP2 WNT3
Tanning	17.06	1	1	2.2	0.00	1.0e+00	TP53INP2
Hand grip strength (left)	3.89	3	1	2.2	0.00	1.0e+00	CAMKMT MMP16 WNT3
Sensitivity / hurt feelings	8.20	2	2	4.4	0.00	1.0e+00	AF131215.9 WNT3
Frequency of depressed mood in last 2 weeks	5.63	3	0	0.0	0.00	1.0e+00	AF131215.9 TMEM106B WNT3
Hearing difficulty/problems: Yes	1.88	1	0	0.0	0.00	1.0e+00	HSD3B7
Relative age of first facial hair	5.70	1	1	2.2	0.00	1.0e+00	WNT3
Systolic blood pressure, automated reading	2.68	2	1	2.2	0.00	1.0e+00	AF131215.9 CCDC36
Impedance of leg (right)	4.68	4	4	8.9	0.67	3.3e-01	AF131215.9 LINC00461 MMP16 TP53INP2
Leg fat-free mass (left)	3.38	5	4	8.9	-0.71	1.8e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Trunk fat percentage	3.34	5	2	4.4	-0.32	6.0e-01	CCDC36 HSD3B7 LINC00461 SLC25A17 WNT3
Hand grip strength (right)	2.78	2	1	2.2	0.00	1.0e+00	CAMKMT WNT3
Current tobacco smoking	2.56	1	0	0.0	0.00	1.0e+00	SLC25A17
Fed-up feelings	7.81	6	2	4.4	0.99	4.6e-05	AF131215.9 ANKRD10 CMTR2 LINC00461 PARP8 WNT3
Relative age voice broke	4.88	1	1	2.2	0.00	1.0e+00	WNT3
Age when periods started (menarche)	1.90	1	0	0.0	0.00	1.0e+00	CCDC36
Heel bone mineral density (BMD) T-score, automated (left)	4.74	2	1	2.2	0.00	1.0e+00	AF131215.9 CCDC36
Qualifications: CSEs or equivalent	1.51	1	0	0.0	0.00	1.0e+00	WNT3
High blood pressure	2.90	2	1	2.2	0.00	1.0e+00	AF131215.9 CCDC36
Medication: Levothyroxine sodium	1.53	1	0	0.0	0.00	1.0e+00	AF131215.9
Sitting height	4.06	3	3	6.7	0.00	1.0e+00	CAMKMT TP53INP2 WNT3
Body mass index (BMI)	3.63	4	2	4.4	-0.38	6.2e-01	AF131215.9 HSD3B7 LINC00461 MMP16
Impedance of leg (left)	5.02	5	4	8.9	0.51	3.8e-01	AF131215.9 LINC00461 MMP16 TP53INP2 WNT3
Leg predicted mass (left)	3.39	5	4	8.9	-0.71	1.8e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Trunk fat mass	3.32	3	2	4.4	0.00	1.0e+00	HSD3B7 LINC00461 WNT3
Waist circumference	2.38	2	1	2.2	0.00	1.0e+00	HSD3B7 LINC00461
Past tobacco smoking	2.37	1	0	0.0	0.00	1.0e+00	WNT3
Nervous feelings	8.39	4	2	4.4	0.98	1.6e-02	AF131215.9 SLC25A17 TP53INP2 WNT3
Frequency of tenseness / restlessness in last 2 weeks	6.62	2	1	2.2	0.00	1.0e+00	TMEM106B WNT3
Hearing difficulty/problems with background noise	2.06	1	0	0.0	0.00	1.0e+00	WNT3
Hair/balding pattern: Pattern 2	3.06	1	1	2.2	0.00	1.0e+00	WNT3
Forced vital capacity (FVC)	4.78	2	2	4.4	0.00	1.0e+00	HSD3B7 WNT3
Heel bone mineral density (BMD) T-score, automated (right)	4.99	3	2	4.4	0.00	1.0e+00	AF131215.9 CCDC36 MMP16
Ever unenthusiastic/disinterested for a whole week	2.68	1	0	0.0	0.00	1.0e+00	WNT3
Mouth/teeth dental problems	2.30	1	0	0.0	0.00	1.0e+00	WNT3
Neuroticism score	15.25	9	6	13.3	0.98	3.1e-06	AF131215.9 ANKRD10 HSD3B7 LINC00461 PARP8 SLC25A17 TMEM106B TP53INP2 WNT3
Weight	3.22	5	3	6.7	-0.45	4.4e-01	AF131215.9 CAMKMT HSD3B7 LINC00461 TP53INP2
Impedance of arm (right)	4.83	7	5	11.1	0.10	8.3e-01	AF131215.9 CCDC36 LINC00461 MMP16 TMEM106B TP53INP2 WNT3
Arm fat percentage (right)	2.75	3	1	2.2	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Trunk fat-free mass	2.79	4	3	6.7	-0.95	5.1e-02	AF131215.9 CAMKMT MMP16 TP53INP2
Hip circumference	3.64	5	4	8.9	-0.44	4.6e-01	AF131215.9 HSD3B7 LINC00461 MMP16 TP53INP2
Time employed in main current job	3.43	1	1	2.2	0.00	1.0e+00	WNT3
Worrier / anxious feelings	8.96	4	3	6.7	0.98	2.4e-02	AF131215.9 HSD3B7 SLC25A17 WNT3
Frequency of tiredness / lethargy in last 2 weeks	4.40	2	1	2.2	0.00	1.0e+00	CCDC36 TMEM106B
Hair/balding pattern: Pattern 3	6.14	1	1	2.2	0.00	1.0e+00	WNT3
Number of live births	1.74	1	0	0.0	0.00	1.0e+00	WNT3
Forced expiratory volume in 1-second (FEV1)	5.28	2	2	4.4	0.00	1.0e+00	HSD3B7 WNT3
Pulse rate	1.58	1	0	0.0	0.00	1.0e+00	CCDC36
Qualifications: A levels/AS levels or equivalent	1.77	1	0	0.0	0.00	1.0e+00	LINC00461
Mouth/teeth dental problems: Dentures	2.16	1	0	0.0	0.00	1.0e+00	TP53INP2
Depression (self-reported)	3.34	1	0	0.0	0.00	1.0e+00	TMEM106B
Forced expiratory volume in 1-second (FEV1), Best measure	5.24	2	2	4.4	0.00	1.0e+00	HSD3B7 WNT3
Impedance of arm (left)	4.70	6	4	8.9	0.11	8.4e-01	AF131215.9 CCDC36 MMP16 TMEM106B TP53INP2 WNT3
Arm fat mass (right)	3.29	3	2	4.4	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Trunk predicted mass	2.85	4	3	6.7	-0.95	5.3e-02	AF131215.9 CAMKMT MMP16 TP53INP2
Standing height	2.22	4	3	6.7	-0.99	5.2e-03	CAMKMT TMEM106B TP53INP2 WNT3
Tense / 'highly strung'	9.85	5	2	4.4	0.99	8.8e-04	AF131215.9 HSD3B7 SLC25A17 TMEM106B TP53INP2
Seen doctor (GP) for nerves, anxiety, tension or depression	5.12	1	1	2.2	0.00	1.0e+00	TMEM106B
Hair/balding pattern: Pattern 4	7.69	1	1	2.2	0.00	1.0e+00	WNT3
Peak expiratory flow (PEF)	4.12	3	1	2.2	0.00	1.0e+00	AF131215.9 CAMKMT WNT3
Qualifications: O levels/GCSEs or equivalent	1.92	1	0	0.0	0.00	1.0e+00	LINC00461
Blood clot in the leg (DVT)	2.29	1	0	0.0	0.00	1.0e+00	TP53INP2
Medication: Paracetamol	3.67	1	1	2.2	0.00	1.0e+00	WNT3
Headache pain in last month	4.05	1	1	2.2	0.00	1.0e+00	WNT3
Hypothyroidism/myxoedema (self-reported)	2.11	1	1	2.2	0.00	1.0e+00	AF131215.9
High blood pressure (siblings)	2.99	1	0	0.0	0.00	1.0e+00	TMEM106B
Forced vital capacity (FVC), Best measure	4.98	2	2	4.4	0.00	1.0e+00	HSD3B7 WNT3
Body fat percentage	2.98	3	1	2.2	0.00	1.0e+00	HSD3B7 LINC00461 WNT3
Leg fat percentage (right)	2.49	2	2	4.4	0.00	1.0e+00	HSD3B7 LINC00461
Arm fat-free mass (right)	3.37	5	3	6.7	-0.76	1.4e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Comparative body size at age 10	3.17	5	1	2.2	-0.47	4.2e-01	AF131215.9 CAMKMT HSD3B7 LINC00461 TP53INP2
Number of full brothers	2.95	1	0	0.0	0.00	1.0e+00	WNT3
Worry too long after embarrassment	6.64	5	1	2.2	0.99	9.2e-04	AF131215.9 ANKRD10 LINC00461 TP53INP2 WNT3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.80	1	0	0.0	0.00	1.0e+00	TMEM106B
Age at first live birth	3.29	1	0	0.0	0.00	1.0e+00	AF131215.9
Qualifications: College or University degree	2.64	2	2	4.4	0.00	1.0e+00	LINC00461 WNT3
Emphysema/chronic bronchitis	2.77	1	0	0.0	0.00	1.0e+00	WNT3
Medication for pain relief, constipation, heartburn	3.35	1	1	2.2	0.00	1.0e+00	WNT3
Neck or shoulder pain in last month	2.34	1	0	0.0	0.00	1.0e+00	CMTR2
Whole body fat mass	3.16	3	1	2.2	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Leg fat mass (right)	3.16	3	2	4.4	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Arm predicted mass (right)	3.38	5	3	6.7	-0.77	1.3e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Pulse rate, automated reading	2.07	2	1	2.2	0.00	1.0e+00	CCDC36 LINC00461
Alcohol intake frequency.	2.92	1	1	2.2	0.00	1.0e+00	WNT3
Comparative height size at age 10	2.02	4	2	4.4	-0.74	2.6e-01	CAMKMT CMTR2 TP53INP2 WNT3
Suffer from 'nerves'	4.80	2	1	2.2	0.00	1.0e+00	AF131215.9 WNT3
Leg pain on walking	2.17	1	0	0.0	0.00	1.0e+00	WNT3
Supplements: Vitamin C	2.13	1	0	0.0	0.00	1.0e+00	WNT3
Hypertension (Self-reported)	2.85	2	1	2.2	0.00	1.0e+00	AF131215.9 CCDC36
Illnesses of father: Heart disease	1.77	1	0	0.0	0.00	1.0e+00	WNT3
Forced expiratory volume in 1-second (FEV1), predicted	1.62	1	1	2.2	0.00	1.0e+00	TP53INP2
Whole body fat-free mass	3.08	5	4	8.9	-0.77	1.3e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Leg fat-free mass (right)	3.35	5	4	8.9	-0.74	1.5e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Arm fat percentage (left)	3.07	3	1	2.2	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Handedness (chirality/laterality): Left-handed	3.30	1	1	2.2	0.00	1.0e+00	WNT3
Mood swings	11.82	6	4	8.9	1.00	2.9e-05	AF131215.9 CMTR2 HSD3B7 SLC25A17 TMEM106B WNT3
Loneliness, isolation	5.26	2	0	0.0	0.00	1.0e+00	TMEM106B WNT3
Mouth/teeth dental problems: Mouth ulcers	3.75	1	1	2.2	0.00	1.0e+00	WNT3
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.55	2	2	4.4	0.00	1.0e+00	HSD3B7 WNT3
Whole body water mass	3.11	5	4	8.9	-0.77	1.3e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Leg predicted mass (right)	3.35	5	4	8.9	-0.74	1.5e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Arm fat mass (left)	3.30	3	2	4.4	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Number of self-reported non-cancer illnesses	2.28	1	0	0.0	0.00	1.0e+00	TMEM106B
Average weekly champagne plus white wine intake	2.28	1	0	0.0	0.00	1.0e+00	WNT3
Miserableness	7.35	3	3	6.7	0.00	1.0e+00	AF131215.9 TMEM106B WNT3
Guilty feelings	5.48	2	1	2.2	0.00	1.0e+00	AF131215.9 WNT3
Medication: Blood pressure	2.41	1	0	0.0	0.00	1.0e+00	AF131215.9
High cholesterol (Self-reported)	2.02	1	0	0.0	0.00	1.0e+00	HSD3B7
Medication: Bendroflumethiazide	2.74	1	1	2.2	0.00	1.0e+00	AF131215.9
Medication: Paracetamol	3.39	1	1	2.2	0.00	1.0e+00	WNT3
Basal metabolic rate	3.14	5	5	11.1	-0.73	1.6e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Leg fat percentage (left)	2.44	3	1	2.2	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Arm fat-free mass (left)	3.18	5	3	6.7	-0.76	1.3e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2
Average weekly beer plus cider intake	2.79	1	0	0.0	0.00	1.0e+00	AF131215.9
Risk taking	2.59	1	0	0.0	0.00	1.0e+00	AF131215.9
Fractured/broken bones in last 5 years	2.93	1	0	0.0	0.00	1.0e+00	WNT3
Diastolic blood pressure, automated reading	2.59	2	2	4.4	0.00	1.0e+00	AF131215.9 LINC00461
Vascular/heart problems diagnosed by doctor	2.60	2	1	2.2	0.00	1.0e+00	AF131215.9 CCDC36
Cholesterol lowering medication	1.57	1	0	0.0	0.00	1.0e+00	HSD3B7
Pain experienced in last month	2.25	1	0	0.0	0.00	1.0e+00	WNT3
Basal cell carcinoma (self-reported)	2.45	1	0	0.0	0.00	1.0e+00	TP53INP2
Deep venous thrombosis (DVT) (self-reported)	2.50	1	0	0.0	0.00	1.0e+00	TP53INP2
Impedance of whole body	5.34	6	6	13.3	0.21	6.9e-01	AF131215.9 CCDC36 LINC00461 MMP16 TP53INP2 WNT3
Leg fat mass (left)	3.16	3	2	4.4	0.00	1.0e+00	AF131215.9 HSD3B7 LINC00461
Arm predicted mass (left)	3.38	5	3	6.7	-0.77	1.3e-01	AF131215.9 CAMKMT LINC00461 MMP16 TP53INP2

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	14	0.401	1.7
GTEx	Adipose Visceral Omentum	10	0.491	1.7
GTEx	Adrenal Gland	9	0.618	1.8
GTEx	Artery Aorta	17	0.571	1.7
GTEx	Artery Coronary	12	1.014	1.9
GTEx	Artery Tibial	11	0.292	1.7
GTEx	Brain Caudate basal ganglia	5	0.543	1.8
GTEx	Brain Cerebellar Hemisphere	8	0.537	1.9
GTEx	Brain Cerebellum	8	0.404	1.7
GTEx	Brain Cortex	8	0.773	1.9
GTEx	Brain Frontal Cortex BA9	8	0.866	1.9
GTEx	Brain Hippocampus	4	0.763	1.7
GTEx	Brain Hypothalamus	4	0.678	1.7
GTEx	Brain Nucleus accumbens basal ganglia	8	0.925	1.8
GTEx	Brain Putamen basal ganglia	4	0.641	1.9
GTEx	Breast Mammary Tissue	10	0.507	1.7
GTEx	Breast Mammary Tissue (Male)	10	0.838	1.6
GTEx	Breast Mammary Tissue (Female)	8	0.487	1.8
GTEx	Cells EBV-transformed lymphocytes	11	0.773	2.0
GTEx	Cells Transformed fibroblasts	11	0.262	1.7
GTEx	Colon Sigmoid	11	0.752	1.8
GTEx	Colon Transverse	15	0.727	1.8
GTEx	Esophagus Gastroesophageal Junction	12	0.830	1.9
GTEx	Esophagus Mucosa	15	0.452	1.8
GTEx	Esophagus Muscularis	16	0.495	1.8
GTEx	Heart Atrial Appendage	9	0.570	1.8
GTEx	Heart Left Ventricle	9	0.588	1.8
GTEx	Liver	3	0.418	1.8
GTEx	Lung	15	0.522	1.7
GTEx	Muscle Skeletal	9	0.311	1.7
GTEx	Nerve Tibial	15	0.347	1.7
GTEx	Ovary	8	0.881	1.9
GTEx	Pancreas	13	0.797	1.8
GTEx	Pituitary	7	0.628	1.8
GTEx	Prostate	5	0.599	1.8
GTEx	Skin Not Sun Exposed Suprapubic	15	0.610	1.8
GTEx	Skin Sun Exposed Lower leg	17	0.467	1.7
GTEx	Small Intestine Terminal Ileum	6	1.302	2.1
GTEx	Spleen	7	0.496	1.8
GTEx	Stomach	10	0.688	1.8
GTEx	Testis	17	0.539	1.8
GTEx	Thyroid	19	0.475	1.7
GTEx	Uterus	9	1.587	2.1
GTEx	Vagina	6	0.945	1.9
GTEx	Whole Blood	8	0.401	1.7
METSIM	Adipose	5	0.108	1.5
NTR	Blood	6	0.250	1.7
ROSMAP	Brain Pre-frontal Cortex	22	0.501	1.9
YFS	Blood	4	0.087	1.5
CommonMind	Brain Pre-frontal Cortex	8	0.149	1.6
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	7	0.423	1.7
The Cancer Genome Atlas	Breast Invasive Carcinoma	8	0.182	1.6
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	3	0.273	1.7
The Cancer Genome Atlas	Colon Adenocarcinoma	5	0.242	1.7
The Cancer Genome Atlas	Esophageal Carcinoma	4	0.584	1.9
The Cancer Genome Atlas	Glioblastoma Multiforme	2	0.196	1.6
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	5	0.184	1.6
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	11	0.268	1.6
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	8	0.390	1.7
The Cancer Genome Atlas	Brain Lower Grade Glioma	8	0.186	1.5
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	4	0.362	1.6
The Cancer Genome Atlas	Lung Adenocarcinoma	6	0.204	1.6
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	5	0.200	1.7
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	6	0.377	1.6
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	4	0.241	1.7
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	5	0.377	1.8
The Cancer Genome Atlas	Prostate Adenocarcinoma	11	0.238	1.6
The Cancer Genome Atlas	Rectum Adenocarcinoma	1	0.145	1.6
The Cancer Genome Atlas	Soft Tissue Sarcoma	2	0.187	1.6
The Cancer Genome Atlas	Skin Cutaneous Melanoma	1	0.187	1.8
The Cancer Genome Atlas	Stomach Adenocarcinoma	6	0.356	1.7
The Cancer Genome Atlas	Testicular Germ Cell Tumors	3	0.235	1.7
The Cancer Genome Atlas	Thyroid Carcinoma	9	0.174	1.6
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	3	0.591	1.8