628 significantly associated models · 84 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 43899918 | 45698128 | 1 | 1 | 8.9e-08 | 3.3e-08 | 1.0e-01 | 91 | CAMKMT |
2 | 3 | 48350366 | 50144951 | 8 | 1 | 2.7e-09 | 6.1e-09 | 1.0e+00 | 100 | CCDC36 |
3 | 5 | 49462228 | 50836718 | 2 | 1 | 6.4e-08 | 9.3e-07 | 1.2e-01 | 90 | PARP8 |
4 | 5 | 87104604 | 88677293 | 1 | 1 | 3.7e-08 | 6.8e-10 | 5.3e-03 | 80 | LINC00461 |
5 | 7 | 11553163 | 12967449 | 1 | 1 | 1.7e-07 | 6.0e-08 | 1.4e-01 | 93 | TMEM106B |
6 | 8 | 8092025 | 13120332 | 35 | 1 | 6.9e-17 | 1.0e-17 | 6.5e-05 | 78 | AF131215.9 |
7 | 8 | 88801153 | 89582625 | 1 | 1 | 1.5e-08 | 4.4e-11 | 7.4e-04 | 74 | MMP16 |
8 | 12 | 15807367 | 17456908 | 1 | 1 | 7.8e-08 | 4.6e-05 | 3.6e-02 | 74 | MGST1 |
9 | 13 | 110831451 | 112257226 | 1 | 1 | 1.5e-07 | 4.6e-06 | 1.0e+00 | 100 | ANKRD10 |
10 | 16 | 30347731 | 31758245 | 6 | 1 | 3.6e-10 | 3.8e-10 | 2.3e-01 | 96 | HSD3B7 |
11 | 16 | 70624483 | 72022941 | 2 | 1 | 2.9e-08 | 7.9e-08 | 1.3e-01 | 92 | CMTR2 |
12 | 17 | 42774693 | 45796313 | 18 | 1 | 1.3e-11 | 1.4e-09 | 3.5e-01 | 98 | WNT3 |
13 | 20 | 32254831 | 34109427 | 4 | 1 | 2.1e-13 | 7.1e-12 | 8.3e-01 | 100 | TP53INP2 |
14 | 22 | 40472399 | 42379813 | 2 | 1 | 9.1e-08 | 7.0e-09 | 2.5e-02 | 85 | SLC25A17 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Small Intestine Terminal Ileum | 6 | 1.302 | 2.1 |
GTEx | Uterus | 9 | 1.587 | 2.1 |
GTEx | Cells EBV-transformed lymphocytes | 11 | 0.773 | 2.0 |
GTEx | Artery Coronary | 12 | 1.014 | 1.9 |
GTEx | Brain Cerebellar Hemisphere | 8 | 0.537 | 1.9 |
GTEx | Brain Cortex | 8 | 0.773 | 1.9 |
GTEx | Brain Frontal Cortex BA9 | 8 | 0.866 | 1.9 |
GTEx | Brain Putamen basal ganglia | 4 | 0.641 | 1.9 |
GTEx | Esophagus Gastroesophageal Junction | 12 | 0.830 | 1.9 |
GTEx | Ovary | 8 | 0.881 | 1.9 |
GTEx | Vagina | 6 | 0.945 | 1.9 |
ROSMAP | Brain Pre-frontal Cortex | 22 | 0.501 | 1.9 |
The Cancer Genome Atlas | Esophageal Carcinoma | 4 | 0.584 | 1.9 |
GTEx | Adrenal Gland | 9 | 0.618 | 1.8 |
GTEx | Brain Caudate basal ganglia | 5 | 0.543 | 1.8 |
GTEx | Brain Nucleus accumbens basal ganglia | 8 | 0.925 | 1.8 |
GTEx | Breast Mammary Tissue (Female) | 8 | 0.487 | 1.8 |
GTEx | Colon Sigmoid | 11 | 0.752 | 1.8 |
GTEx | Colon Transverse | 15 | 0.727 | 1.8 |
GTEx | Esophagus Mucosa | 15 | 0.452 | 1.8 |
GTEx | Esophagus Muscularis | 16 | 0.495 | 1.8 |
GTEx | Heart Atrial Appendage | 9 | 0.570 | 1.8 |
GTEx | Heart Left Ventricle | 9 | 0.588 | 1.8 |
GTEx | Liver | 3 | 0.418 | 1.8 |
GTEx | Pancreas | 13 | 0.797 | 1.8 |
GTEx | Pituitary | 7 | 0.628 | 1.8 |
GTEx | Prostate | 5 | 0.599 | 1.8 |
GTEx | Skin Not Sun Exposed Suprapubic | 15 | 0.610 | 1.8 |
GTEx | Spleen | 7 | 0.496 | 1.8 |
GTEx | Stomach | 10 | 0.688 | 1.8 |
GTEx | Testis | 17 | 0.539 | 1.8 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 5 | 0.377 | 1.8 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.187 | 1.8 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 3 | 0.591 | 1.8 |
GTEx | Adipose Subcutaneous | 14 | 0.401 | 1.7 |
GTEx | Adipose Visceral Omentum | 10 | 0.491 | 1.7 |
GTEx | Artery Aorta | 17 | 0.571 | 1.7 |
GTEx | Artery Tibial | 11 | 0.292 | 1.7 |
GTEx | Brain Cerebellum | 8 | 0.404 | 1.7 |
GTEx | Brain Hippocampus | 4 | 0.763 | 1.7 |
GTEx | Brain Hypothalamus | 4 | 0.678 | 1.7 |
GTEx | Breast Mammary Tissue | 10 | 0.507 | 1.7 |
GTEx | Cells Transformed fibroblasts | 11 | 0.262 | 1.7 |
GTEx | Lung | 15 | 0.522 | 1.7 |
GTEx | Muscle Skeletal | 9 | 0.311 | 1.7 |
GTEx | Nerve Tibial | 15 | 0.347 | 1.7 |
GTEx | Skin Sun Exposed Lower leg | 17 | 0.467 | 1.7 |
GTEx | Thyroid | 19 | 0.475 | 1.7 |
GTEx | Whole Blood | 8 | 0.401 | 1.7 |
NTR | Blood | 6 | 0.250 | 1.7 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 7 | 0.423 | 1.7 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.273 | 1.7 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 5 | 0.242 | 1.7 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 8 | 0.390 | 1.7 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 5 | 0.200 | 1.7 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 4 | 0.241 | 1.7 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 6 | 0.356 | 1.7 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 3 | 0.235 | 1.7 |
GTEx | Breast Mammary Tissue (Male) | 10 | 0.838 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 8 | 0.149 | 1.6 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 8 | 0.182 | 1.6 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 2 | 0.196 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 5 | 0.184 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 11 | 0.268 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 4 | 0.362 | 1.6 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 6 | 0.204 | 1.6 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 6 | 0.377 | 1.6 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 11 | 0.238 | 1.6 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 1 | 0.145 | 1.6 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 2 | 0.187 | 1.6 |
The Cancer Genome Atlas | Thyroid Carcinoma | 9 | 0.174 | 1.6 |
METSIM | Adipose | 5 | 0.108 | 1.5 |
YFS | Blood | 4 | 0.087 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 8 | 0.186 | 1.5 |