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chr19:32,209,988-33,668,090

Best TWAS P=3.91e-10 · Best GWAS P=1e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DPY19L3 0.07 0.05 lasso 2 0.06 8.7e-08 -6.1 -6.3 3.9e-10 0.96 0.01 0.99 TRUE
2 GTEx Cells Transformed fibroblasts DPY19L3 0.19 0.12 lasso 6 0.10 9.4e-08 -5.6 -6.1 1.3e-09 0.81 0.03 0.97 FALSE
3 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPY19L3 0.04 0.03 blup 60 0.02 2.2e-03 -5.7 -5.5 3.2e-08 0.77 0.02 0.89 FALSE
4 The Cancer Genome Atlas Brain Lower Grade Glioma DPY19L3 0.05 0.06 blup 62 0.05 1.3e-06 -5.7 -5.8 7.3e-09 0.81 0.02 0.98 FALSE
5 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF507 0.05 0.03 blup 39 0.05 1.3e-06 -5.0 -5.2 1.9e-07 0.67 0.01 0.98 FALSE
6 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DPY19L3 0.04 0.04 lasso 1 0.03 7.5e-05 -5.8 -5.8 8.4e-09 0.81 0.02 0.98 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma DPY19L3 0.04 0.05 blup 60 0.03 6.1e-04 -5.6 -5.3 1.1e-07 0.80 0.03 0.96 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma DPY19L3 0.05 0.04 enet 9 0.05 2.1e-05 -5.6 -5.9 3.5e-09 0.87 0.02 0.98 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma ZNF507 0.14 0.14 lasso 5 0.18 2.4e-17 -5.7 -5.6 2.3e-08 0.73 0.00 1.00 FALSE