[Hub]/) : Traits : Fed-up feelings :

chr11:63,316,786-64,820,283

Best TWAS P=1.47e-08 · Best GWAS P=7.92e-08 conditioned to 0.00246

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC88B 0.22 0.24 bslmm 358 0.25 5.8e-30 -5.2 5.2 2.2e-07 -0.54 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex PPP1R14B 0.10 0.09 lasso 5 0.09 1.1e-10 -5.1 5.2 2.2e-07 -0.54 0.01 0.99 FALSE
3 GTEx Artery Aorta PPP1R14B 0.12 0.03 lasso 4 0.08 3.0e-05 -5.2 5.7 1.5e-08 -0.48 0.02 0.95 TRUE
4 GTEx Brain Cerebellar Hemisphere CCDC88B 0.45 0.39 lasso 3 0.41 1.2e-11 -5.2 5.4 8.2e-08 -0.57 0.02 0.98 FALSE
5 GTEx Brain Cerebellum CCDC88B 0.48 0.55 lasso 4 0.54 1.6e-18 -5.2 5.1 2.9e-07 -0.51 0.01 0.99 FALSE
6 GTEx Esophagus Muscularis CCDC88B 0.09 0.00 lasso 3 0.06 1.1e-04 3.4 5.3 1.2e-07 -0.42 0.04 0.69 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC88B 0.02 0.02 enet 9 0.02 2.4e-05 -5.2 5.6 2.5e-08 -0.60 0.01 0.99 FALSE