Best TWAS P=9.17e-09 · Best GWAS P=2.99e-08 conditioned to 0.0785
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | IGSF9B | 0.27 | 0.01 | enet | 7 | -0.01 | 5.4e-01 | -4.6 | -5.1 | 3.0e-07 | 0.56 | 0.06 | 0.33 | FALSE |
| 2 | GTEx | Testis | IGSF9B | 0.19 | 0.09 | lasso | 7 | 0.10 | 3.4e-05 | -4.7 | -5.7 | 9.2e-09 | 0.77 | 0.01 | 0.98 | TRUE |
| 3 | GTEx | Thyroid | IGSF9B | 0.28 | 0.20 | enet | 9 | 0.22 | 1.2e-16 | -4.6 | -5.6 | 2.6e-08 | 0.73 | 0.14 | 0.84 | FALSE |
| 4 | GTEx | Whole Blood | IGSF9B | 0.11 | 0.03 | enet | 22 | 0.06 | 7.2e-06 | -4.7 | -5.3 | 1.5e-07 | 0.57 | 0.03 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | IGSF9B | 0.08 | 0.10 | lasso | 2 | 0.11 | 3.8e-11 | -4.7 | -5.6 | 2.2e-08 | 0.70 | 0.16 | 0.84 | FALSE |