Best TWAS P=5.58e-09 · Best GWAS P=7.25e-09 conditioned to 0.0164
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | -5.2 | -5.8 | 5.6e-09 | 0.70 | 0.07 | 0.93 | TRUE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CADM2 | 0.14 | 0.05 | blup | 339 | 0.09 | 2.7e-04 | -4.9 | -5.3 | 1.3e-07 | 0.45 | 0.06 | 0.75 | FALSE |