220 significantly associated models · 46 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 7715776 | 9571422 | 2 | 1 | 1.4e-07 | 4.8e-08 | 0.0291 | 84 | RERE |
2 | 1 | 173103273 | 175663031 | 2 | 1 | 1.1e-08 | 3.2e-09 | 1.0000 | 100 | RABGAP1L |
3 | 3 | 49615624 | 51077419 | 3 | 1 | 8.4e-08 | 1.1e-07 | 0.0507 | 86 | CYB561D2 |
4 | 3 | 51616334 | 53015839 | 1 | 1 | 1.5e-07 | 6.5e-06 | 0.8440 | 100 | WDR82 |
5 | 3 | 84317575 | 86808226 | 1 | 1 | 5.6e-09 | 7.3e-09 | 0.0164 | 83 | CADM2 |
6 | 5 | 64115004 | 65711805 | 6 | 1 | 1.6e-09 | 1.1e-09 | 0.1430 | 94 | CTC-534A2.2 |
7 | 6 | 147140769 | 148587096 | 1 | 1 | 2.9e-07 | 1.6e-06 | 0.1630 | 92 | SAMD5 |
8 | 7 | 11553163 | 12967449 | 1 | 1 | 1.3e-07 | 2.9e-09 | 0.0023 | 74 | TMEM106B |
9 | 8 | 8092025 | 12966739 | 15 | 1 | 3.8e-13 | 5.7e-11 | 0.0063 | 83 | AF131215.9 |
10 | 9 | 95502571 | 96913764 | 2 | 1 | 2.8e-08 | 2.9e-08 | 0.1260 | 92 | RP11-165J3.6 |
11 | 16 | 30347731 | 31833122 | 8 | 1 | 4.2e-08 | 6.3e-08 | 0.3130 | 96 | MYST1 |
12 | 17 | 34256906 | 35644076 | 1 | 1 | 3.0e-08 | 3.1e-04 | 0.5420 | 97 | DHRS11 |
13 | 22 | 40946307 | 42614362 | 3 | 1 | 5.2e-08 | 3.9e-08 | 0.1570 | 93 | L3MBTL2 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Small Intestine Terminal Ileum | 1 | 0.217 | 2.1 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.9 |
GTEx | Ovary | 0 | 0.000 | 1.9 |
GTEx | Pituitary | 3 | 0.269 | 1.9 |
GTEx | Spleen | 2 | 0.142 | 1.9 |
The Cancer Genome Atlas | Esophageal Carcinoma | 2 | 0.292 | 1.9 |
GTEx | Adipose Visceral Omentum | 4 | 0.196 | 1.8 |
GTEx | Artery Coronary | 1 | 0.085 | 1.8 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.8 |
GTEx | Brain Cerebellar Hemisphere | 2 | 0.134 | 1.8 |
GTEx | Brain Cortex | 1 | 0.097 | 1.8 |
GTEx | Brain Frontal Cortex BA9 | 1 | 0.108 | 1.8 |
GTEx | Breast Mammary Tissue | 4 | 0.203 | 1.8 |
GTEx | Cells EBV-transformed lymphocytes | 2 | 0.141 | 1.8 |
GTEx | Colon Transverse | 6 | 0.291 | 1.8 |
GTEx | Esophagus Gastroesophageal Junction | 3 | 0.208 | 1.8 |
GTEx | Esophagus Muscularis | 6 | 0.186 | 1.8 |
GTEx | Heart Atrial Appendage | 3 | 0.190 | 1.8 |
GTEx | Heart Left Ventricle | 4 | 0.261 | 1.8 |
GTEx | Lung | 8 | 0.278 | 1.8 |
GTEx | Skin Not Sun Exposed Suprapubic | 6 | 0.244 | 1.8 |
GTEx | Stomach | 3 | 0.206 | 1.8 |
GTEx | Testis | 6 | 0.190 | 1.8 |
GTEx | Uterus | 4 | 0.705 | 1.8 |
ROSMAP | Brain Pre-frontal Cortex | 16 | 0.364 | 1.8 |
GTEx | Adipose Subcutaneous | 6 | 0.172 | 1.7 |
GTEx | Adrenal Gland | 4 | 0.275 | 1.7 |
GTEx | Artery Aorta | 6 | 0.202 | 1.7 |
GTEx | Artery Tibial | 7 | 0.186 | 1.7 |
GTEx | Brain Cerebellum | 1 | 0.050 | 1.7 |
GTEx | Brain Putamen basal ganglia | 2 | 0.321 | 1.7 |
GTEx | Breast Mammary Tissue (Male) | 1 | 0.084 | 1.7 |
GTEx | Breast Mammary Tissue (Female) | 3 | 0.182 | 1.7 |
GTEx | Colon Sigmoid | 4 | 0.274 | 1.7 |
GTEx | Esophagus Mucosa | 8 | 0.241 | 1.7 |
GTEx | Liver | 0 | 0.000 | 1.7 |
GTEx | Nerve Tibial | 7 | 0.162 | 1.7 |
GTEx | Pancreas | 3 | 0.184 | 1.7 |
GTEx | Prostate | 2 | 0.240 | 1.7 |
GTEx | Skin Sun Exposed Lower leg | 8 | 0.220 | 1.7 |
GTEx | Thyroid | 8 | 0.200 | 1.7 |
GTEx | Vagina | 1 | 0.157 | 1.7 |
GTEx | Whole Blood | 1 | 0.050 | 1.7 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 3 | 0.226 | 1.7 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 2 | 0.156 | 1.7 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.6 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.6 |
GTEx | Cells Transformed fibroblasts | 3 | 0.071 | 1.6 |
GTEx | Muscle Skeletal | 3 | 0.104 | 1.6 |
METSIM | Adipose | 7 | 0.152 | 1.6 |
NTR | Blood | 4 | 0.167 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 3 | 0.056 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.121 | 1.6 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 1 | 0.048 | 1.6 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 4 | 0.147 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 2 | 0.098 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 3 | 0.271 | 1.6 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 2 | 0.080 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 1 | 0.022 | 1.6 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 1 | 0.059 | 1.6 |
YFS | Blood | 5 | 0.108 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 3 | 0.068 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.024 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 3 | 0.070 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.068 | 1.5 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 2 | 0.126 | 1.5 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 3 | 0.058 | 1.5 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.5 |