Best TWAS P=2.28e-07 · Best GWAS P=7.7e-08 conditioned to 0.124
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | PFDN1 | 0.15 | 0.06 | enet | 11 | 0.04 | 0.0186 | -4.1 | 5.1 | 2.6e-07 | -0.74 | 0.06 | 0.66 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | PFDN1 | 0.03 | 0.02 | blup | 47 | 0.02 | 0.0055 | -5.2 | 5.2 | 2.3e-07 | -0.93 | 0.01 | 0.89 | TRUE |