Best TWAS P=1.48e-09 · Best GWAS P=3.51e-08 conditioned to 0.327
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | RP11-53O19.3 | 0.04 | 0.04 | enet | 8 | 0.05 | 7.8e-05 | 4.4 | -5.8 | 8.5e-09 | -0.77 | 0.11 | 0.8 | FALSE |
2 | GTEx | Skin Not Sun Exposed Suprapubic | RP11-53O19.3 | 0.05 | 0.07 | lasso | 2 | 0.04 | 3.6e-03 | 5.4 | -5.4 | 6.5e-08 | -0.97 | 0.02 | 0.9 | FALSE |
3 | GTEx | Spleen | RP11-53O19.3 | 0.26 | 0.13 | enet | 12 | 0.06 | 1.2e-02 | 4.7 | -6.0 | 1.5e-09 | -0.82 | 0.12 | 0.5 | TRUE |