[Hub]/) : Traits : Basal cell carcinoma (self-reported) : ←

chr20:32,594,714-34,225,302

Best TWAS P=7.49e-09 · Best GWAS P=3.69e-11 conditioned to 2.73e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Esophagus Mucosa	NCOA6	0.10	0.06	lasso	16	0.09	8.0e-07	-3.7	5.8	7.5e-09	0.53	0.66	0.31	TRUE
10	GTEx	Heart Left Ventricle	NCOA6	0.09	0.01	enet	19	0.05	1.1e-03	-3.5	5.8	8.7e-09	0.43	0.45	0.18	FALSE
2	GTEx	Brain Frontal Cortex BA9	NCOA6	0.13	0.00	enet	30	0.06	1.3e-02	-3.5	5.7	1.0e-08	0.68	0.12	0.40	FALSE
11	GTEx	Thyroid	NCOA6	0.16	0.12	enet	29	0.16	2.1e-12	4.6	5.6	2.8e-08	0.56	0.99	0.01	FALSE
3	GTEx	Brain Nucleus accumbens basal ganglia	NCOA6	0.24	0.01	lasso	12	0.08	3.2e-03	-3.6	5.4	5.1e-08	0.56	0.25	0.11	FALSE
4	GTEx	Breast Mammary Tissue	NCOA6	0.12	0.02	enet	35	0.04	4.5e-03	-3.6	5.4	6.6e-08	0.57	0.12	0.68	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	NCOA6	0.07	0.08	blup	365	0.09	1.9e-11	-3.5	5.4	8.0e-08	0.50	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	NCOA6	0.03	0.01	blup	65	0.02	5.2e-03	4.6	5.2	1.5e-07	0.54	0.02	0.28	FALSE
1	GTEx	Brain Cortex	NCOA6	0.14	0.03	enet	13	0.05	1.6e-02	-3.6	5.2	1.6e-07	0.57	0.10	0.34	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	NCOA6	0.24	0.07	lasso	4	0.08	5.9e-04	4.6	5.2	1.6e-07	0.56	0.25	0.40	FALSE
12	METSIM	Adipose	NCOA6	0.05	0.02	bslmm	373	0.02	1.3e-04	3.0	5.2	1.7e-07	0.60	0.95	0.01	FALSE
8	GTEx	Esophagus Muscularis	NCOA6	0.14	0.10	enet	22	0.20	2.6e-12	-3.5	5.2	2.0e-07	0.53	1.00	0.00	FALSE
14	YFS	Blood	NCOA6	0.03	0.03	blup	368	0.03	6.9e-10	-3.6	5.2	2.0e-07	0.52	1.00	0.00	FALSE
5	GTEx	Breast Mammary Tissue (Female)	NCOA6	0.08	-0.01	lasso	4	0.00	4.6e-01	4.2	5.2	2.4e-07	0.64	0.04	0.46	FALSE
9	GTEx	Heart Left Ventricle	GSS	0.12	0.06	enet	10	0.04	2.2e-03	3.7	5.1	3.1e-07	0.48	0.76	0.01	FALSE