[Hub]/) : Traits : Basal cell carcinoma (self-reported) :

chr20:32,594,714-34,225,302

Best TWAS P=7.49e-09 · Best GWAS P=3.69e-11 conditioned to 2.73e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cortex NCOA6 0.14 0.03 enet 13 0.05 1.6e-02 -3.6 5.2 1.6e-07 0.57 0.10 0.34 FALSE
2 GTEx Brain Frontal Cortex BA9 NCOA6 0.13 0.00 enet 30 0.06 1.3e-02 -3.5 5.7 1.0e-08 0.68 0.12 0.40 FALSE
3 GTEx Brain Nucleus accumbens basal ganglia NCOA6 0.24 0.01 lasso 12 0.08 3.2e-03 -3.6 5.4 5.1e-08 0.56 0.25 0.11 FALSE
4 GTEx Breast Mammary Tissue NCOA6 0.12 0.02 enet 35 0.04 4.5e-03 -3.6 5.4 6.6e-08 0.57 0.12 0.68 FALSE
5 GTEx Breast Mammary Tissue (Female) NCOA6 0.08 -0.01 lasso 4 0.00 4.6e-01 4.2 5.2 2.4e-07 0.64 0.04 0.46 FALSE
6 GTEx Esophagus Gastroesophageal Junction NCOA6 0.24 0.07 lasso 4 0.08 5.9e-04 4.6 5.2 1.6e-07 0.56 0.25 0.40 FALSE
7 GTEx Esophagus Mucosa NCOA6 0.10 0.06 lasso 16 0.09 8.0e-07 -3.7 5.8 7.5e-09 0.53 0.66 0.31 TRUE
8 GTEx Esophagus Muscularis NCOA6 0.14 0.10 enet 22 0.20 2.6e-12 -3.5 5.2 2.0e-07 0.53 1.00 0.00 FALSE
9 GTEx Heart Left Ventricle GSS 0.12 0.06 enet 10 0.04 2.2e-03 3.7 5.1 3.1e-07 0.48 0.76 0.01 FALSE
10 GTEx Heart Left Ventricle NCOA6 0.09 0.01 enet 19 0.05 1.1e-03 -3.5 5.8 8.7e-09 0.43 0.45 0.18 FALSE
11 GTEx Thyroid NCOA6 0.16 0.12 enet 29 0.16 2.1e-12 4.6 5.6 2.8e-08 0.56 0.99 0.01 FALSE
12 METSIM Adipose NCOA6 0.05 0.02 bslmm 373 0.02 1.3e-04 3.0 5.2 1.7e-07 0.60 0.95 0.01 FALSE
13 ROSMAP Brain Pre-frontal Cortex NCOA6 0.07 0.08 blup 365 0.09 1.9e-11 -3.5 5.4 8.0e-08 0.50 1.00 0.00 FALSE
14 YFS Blood NCOA6 0.03 0.03 blup 368 0.03 6.9e-10 -3.6 5.2 2.0e-07 0.52 1.00 0.00 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma NCOA6 0.03 0.01 blup 65 0.02 5.2e-03 4.6 5.2 1.5e-07 0.54 0.02 0.28 FALSE