[Hub]/) : Traits : Basal cell carcinoma (self-reported) : ← →

chr16:88,934,149-90,172,696

Best TWAS P=1.14e-22 · Best GWAS P=6.66e-17 conditioned to 0.837

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	GTEx	Artery Tibial	DBNDD1	0.31	0.20	enet	20	0.27	2.0e-21	8.35	9.8	1.1e-22	0.86	0.00	1.00	TRUE
28	GTEx	Colon Sigmoid	DBNDD1	0.42	0.13	lasso	5	0.18	7.6e-07	8.35	8.9	5.4e-19	0.91	0.00	1.00	FALSE
19	GTEx	Brain Cerebellum	GAS8	0.60	0.41	lasso	10	0.37	8.0e-12	8.35	8.8	1.2e-18	0.99	0.00	1.00	FALSE
21	GTEx	Brain Cerebellum	URAHP	0.60	0.38	lasso	9	0.33	1.7e-10	8.35	8.8	2.0e-18	0.97	0.00	1.00	FALSE
35	GTEx	Heart Atrial Appendage	DBNDD1	0.52	0.29	enet	27	0.27	9.8e-13	8.35	8.7	4.2e-18	0.89	0.00	1.00	FALSE
37	GTEx	Heart Left Ventricle	DBNDD1	0.24	0.18	lasso	4	0.20	7.6e-11	8.35	8.7	4.5e-18	0.96	0.00	1.00	FALSE
3	GTEx	Adipose Subcutaneous	DBNDD1	0.25	0.02	lasso	7	0.03	2.6e-03	8.35	8.7	5.0e-18	0.92	0.00	1.00	FALSE
42	GTEx	Nerve Tibial	DBNDD1	0.25	0.15	lasso	4	0.11	3.3e-08	8.35	8.5	2.0e-17	0.99	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C16orf3	0.19	0.10	enet	17	0.10	2.7e-12	8.35	8.5	2.4e-17	0.86	0.00	1.00	FALSE
13	GTEx	Artery Coronary	DBNDD1	0.28	0.19	lasso	2	0.13	3.2e-05	8.35	8.5	2.5e-17	1.00	0.00	1.00	FALSE
63	GTEx	Thyroid	DBNDD1	0.26	0.21	lasso	4	0.20	1.2e-15	8.35	8.3	8.2e-17	0.98	0.00	1.00	FALSE
30	GTEx	Colon Transverse	DBNDD1	0.62	0.40	enet	40	0.44	1.2e-22	8.35	8.1	5.9e-16	0.91	0.00	1.00	FALSE
58	GTEx	Stomach	DBNDD1	0.16	0.07	lasso	2	0.11	4.2e-06	8.35	8.0	1.1e-15	0.84	0.00	1.00	FALSE
38	GTEx	Lung	DBNDD1	0.24	0.14	lasso	6	0.16	1.7e-12	8.35	7.9	2.8e-15	0.92	0.00	1.00	FALSE
33	GTEx	Esophagus Muscularis	DBNDD1	0.32	0.13	enet	23	0.14	1.2e-08	8.35	7.9	3.8e-15	0.82	0.00	1.00	FALSE
27	GTEx	Cells Transformed fibroblasts	DBNDD1	0.32	0.20	enet	36	0.20	1.2e-14	8.35	7.8	5.0e-15	0.91	0.00	1.00	FALSE
75	The Cancer Genome Atlas	Prostate Adenocarcinoma	DPEP1	0.08	0.03	enet	3	0.04	3.2e-05	7.45	7.8	8.1e-15	0.84	0.00	1.00	FALSE
50	GTEx	Skin Not Sun Exposed Suprapubic	DBNDD1	0.40	0.19	lasso	5	0.19	8.2e-11	8.35	7.7	1.3e-14	0.96	0.00	1.00	FALSE
23	GTEx	Brain Cortex	GAS8	0.28	0.16	lasso	6	0.14	1.3e-04	8.35	7.7	1.5e-14	0.93	0.00	0.99	FALSE
16	GTEx	Brain Cerebellar Hemisphere	GAS8	0.66	0.33	enet	59	0.36	3.7e-10	8.35	7.7	1.6e-14	0.74	0.00	1.00	FALSE
66	METSIM	Adipose	DBNDD1	0.27	0.04	bslmm	271	0.08	2.3e-12	8.35	7.6	2.8e-14	0.69	0.00	1.00	FALSE
18	GTEx	Brain Cerebellar Hemisphere	URAHP	0.66	0.28	enet	53	0.46	1.7e-13	8.35	7.6	4.2e-14	0.75	0.00	1.00	FALSE
68	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C16orf55	0.07	0.05	enet	3	0.04	8.2e-06	7.10	-7.2	7.1e-13	-0.81	0.00	0.99	FALSE
67	METSIM	Adipose	RP11-368I7.4	0.04	0.03	enet	12	0.02	2.2e-04	5.20	7.1	1.5e-12	0.19	0.66	0.02	FALSE
6	GTEx	Adrenal Gland	DBNDD1	0.45	0.24	lasso	9	0.28	1.2e-10	8.35	7.1	1.6e-12	0.89	0.00	1.00	FALSE
20	GTEx	Brain Cerebellum	CDK10	0.44	0.12	enet	23	0.28	5.1e-09	5.20	-7.1	1.7e-12	-0.19	0.82	0.02	FALSE
25	GTEx	Breast Mammary Tissue (Male)	SNORD68	0.12	0.00	enet	28	0.03	8.2e-02	7.10	6.9	6.2e-12	0.57	0.02	0.62	FALSE
12	GTEx	Artery Aorta	CDK10	0.33	0.07	enet	27	0.18	2.7e-10	5.20	-6.7	2.9e-11	-0.19	0.99	0.00	FALSE
24	GTEx	Brain Cortex	URAHP	0.34	0.19	enet	15	0.17	2.4e-05	8.35	6.6	4.4e-11	0.85	0.00	1.00	FALSE
74	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DBNDD1	0.21	0.01	blup	66	0.10	7.5e-05	6.60	6.6	4.7e-11	0.58	0.04	0.48	FALSE
53	GTEx	Skin Sun Exposed Lower leg	DBNDD1	0.27	0.05	enet	32	0.14	6.9e-12	8.35	6.6	5.6e-11	0.58	0.00	1.00	FALSE
45	GTEx	Pancreas	DBNDD1	0.26	0.16	enet	15	0.18	5.6e-08	8.35	6.5	7.4e-11	0.85	0.00	1.00	FALSE
71	The Cancer Genome Atlas	Brain Lower Grade Glioma	CENPBD1	0.07	0.03	enet	13	0.04	2.4e-05	7.14	6.5	9.3e-11	0.37	0.00	0.98	FALSE
60	GTEx	Stomach	CDK10	0.35	0.12	enet	12	0.22	6.4e-11	5.20	-6.4	1.3e-10	-0.22	0.90	0.00	FALSE
4	GTEx	Adipose Subcutaneous	CDK10	0.37	0.20	enet	50	0.26	4.0e-21	4.34	-6.4	2.1e-10	-0.23	1.00	0.00	FALSE
52	GTEx	Skin Not Sun Exposed Suprapubic	CDK10	0.27	0.19	lasso	9	0.28	1.2e-15	4.34	-6.3	2.3e-10	-0.27	1.00	0.00	FALSE
43	GTEx	Nerve Tibial	CDK10	0.42	0.28	enet	16	0.35	1.2e-25	4.34	-6.3	2.8e-10	-0.28	1.00	0.00	FALSE
29	GTEx	Colon Sigmoid	CDK10	0.37	0.12	lasso	8	0.22	2.2e-08	5.20	-6.3	3.7e-10	-0.15	0.60	0.02	FALSE
62	GTEx	Testis	CDK10	0.28	0.14	lasso	6	0.24	4.1e-11	4.10	-6.3	3.9e-10	-0.29	0.99	0.00	FALSE
11	GTEx	Artery Aorta	SPATA33	0.19	0.06	enet	15	0.12	3.7e-07	-3.58	-6.2	5.1e-10	-0.57	0.78	0.21	FALSE
17	GTEx	Brain Cerebellar Hemisphere	CDK10	0.62	0.20	enet	33	0.28	6.4e-08	5.20	-6.2	5.6e-10	-0.23	0.54	0.11	FALSE
49	GTEx	Prostate	CDK10	0.41	0.16	lasso	6	0.24	1.0e-06	5.20	-6.2	5.7e-10	-0.17	0.16	0.06	FALSE
15	GTEx	Artery Tibial	CDK10	0.29	0.10	enet	15	0.22	2.4e-17	5.20	-6.2	7.5e-10	-0.17	1.00	0.00	FALSE
32	GTEx	Esophagus Mucosa	CDK10	0.36	0.15	lasso	6	0.23	1.9e-15	5.20	-6.1	1.0e-09	-0.17	1.00	0.00	FALSE
54	GTEx	Skin Sun Exposed Lower leg	SPATA33	0.10	0.01	enet	25	0.05	6.3e-05	2.19	-6.1	1.3e-09	-0.64	0.02	0.96	FALSE
34	GTEx	Esophagus Muscularis	CDK10	0.24	0.11	enet	19	0.14	4.3e-09	5.20	-6.0	1.6e-09	-0.10	0.99	0.00	FALSE
57	GTEx	Spleen	DBNDD1	0.21	0.10	lasso	4	0.13	4.1e-04	6.60	6.0	1.7e-09	0.70	0.07	0.32	FALSE
76	The Cancer Genome Atlas	Stomach Adenocarcinoma	C16orf55	0.09	0.04	blup	36	0.04	7.1e-04	4.25	-6.0	1.9e-09	-0.55	0.13	0.69	FALSE
22	GTEx	Brain Cortex	DBNDD1	0.48	0.14	lasso	5	0.12	2.7e-04	-3.92	-6.0	2.1e-09	-0.27	0.04	0.20	FALSE
65	METSIM	Adipose	CDK10	0.23	0.14	lasso	12	0.21	7.9e-31	5.20	-6.0	2.6e-09	-0.16	1.00	0.00	FALSE
9	GTEx	Adrenal Gland	URAHP	0.22	0.04	enet	16	0.17	8.2e-07	8.35	5.9	2.8e-09	0.67	0.00	0.97	FALSE
31	GTEx	Colon Transverse	CDK10	0.34	0.15	lasso	5	0.16	4.2e-08	4.25	-5.8	5.7e-09	-0.28	0.91	0.00	FALSE
36	GTEx	Heart Atrial Appendage	CDK10	0.26	0.07	lasso	3	0.13	1.4e-06	-3.31	-5.8	5.8e-09	-0.24	0.39	0.13	FALSE
26	GTEx	Breast Mammary Tissue (Male)	SPIRE2	0.27	-0.01	enet	29	0.04	3.4e-02	5.07	-5.8	5.9e-09	-0.41	0.04	0.28	FALSE
72	The Cancer Genome Atlas	Brain Lower Grade Glioma	DPEP1	0.06	0.01	blup	44	0.02	1.6e-03	5.07	5.8	6.1e-09	0.43	0.17	0.11	FALSE
64	GTEx	Thyroid	CDK10	0.36	0.16	lasso	9	0.21	9.7e-16	-3.54	-5.8	6.2e-09	-0.32	1.00	0.00	FALSE
41	GTEx	Muscle Skeletal	CDK10	0.17	0.12	lasso	6	0.10	9.2e-10	5.20	-5.8	7.1e-09	-0.06	1.00	0.00	FALSE
39	GTEx	Lung	CDK10	0.25	0.18	lasso	7	0.19	1.0e-14	4.25	-5.7	9.7e-09	-0.29	1.00	0.00	FALSE
44	GTEx	Ovary	CDK10	0.45	0.11	lasso	8	0.25	6.8e-07	5.20	-5.7	9.9e-09	-0.20	0.26	0.06	FALSE
46	GTEx	Pancreas	CDK10	0.18	-0.01	lasso	5	0.02	5.1e-02	4.25	-5.7	1.2e-08	-0.28	0.11	0.06	FALSE
56	GTEx	Small Intestine Terminal Ileum	VPS9D1	0.34	0.04	enet	11	0.11	2.4e-03	5.20	5.6	1.7e-08	0.10	0.16	0.05	FALSE
10	GTEx	Artery Aorta	SPATA2L	0.08	0.00	enet	10	0.05	6.6e-04	7.14	5.6	2.2e-08	0.46	0.12	0.38	FALSE
51	GTEx	Skin Not Sun Exposed Suprapubic	GAS8	0.24	0.00	enet	23	0.08	2.6e-05	-1.79	5.5	3.7e-08	0.46	0.14	0.24	FALSE
2	CommonMind	Brain Pre-frontal Cortex	C16orf55	0.06	0.02	lasso	3	0.02	6.2e-04	4.25	-5.5	4.0e-08	-0.49	0.38	0.59	FALSE
5	GTEx	Adipose Visceral Omentum	CDK10	0.43	0.19	lasso	6	0.32	3.6e-17	5.20	-5.4	6.1e-08	-0.10	1.00	0.00	FALSE
40	GTEx	Muscle Skeletal	SPATA33	0.10	0.04	enet	5	0.05	8.3e-06	4.25	-5.4	7.7e-08	-0.49	0.97	0.01	FALSE
70	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CENPBD1	0.14	0.01	enet	17	0.04	6.3e-05	1.58	5.4	7.9e-08	0.12	0.00	0.97	FALSE
61	GTEx	Stomach	URAHP	0.19	0.01	enet	15	0.11	9.7e-06	-0.33	5.3	9.0e-08	0.47	0.02	0.47	FALSE
7	GTEx	Adrenal Gland	GAS8	0.34	0.10	enet	34	0.24	3.4e-09	8.35	5.3	1.1e-07	0.65	0.00	0.99	FALSE
69	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDK10	0.13	0.01	enet	12	0.02	2.6e-03	-1.55	-5.3	1.1e-07	-0.26	0.02	0.10	FALSE
59	GTEx	Stomach	GAS8	0.16	-0.01	enet	26	0.06	7.0e-04	2.83	5.3	1.2e-07	0.46	0.03	0.48	FALSE
47	GTEx	Pituitary	SPATA33	0.29	0.18	lasso	6	0.15	1.6e-04	4.25	-5.3	1.4e-07	-0.43	0.07	0.39	FALSE
73	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CENPBD1	0.08	0.04	enet	8	0.03	2.2e-02	7.14	5.2	1.9e-07	0.28	0.00	0.90	FALSE
8	GTEx	Adrenal Gland	CDK10	0.26	0.04	enet	11	0.16	2.7e-06	5.20	-5.2	2.1e-07	-0.10	0.10	0.04	FALSE
48	GTEx	Pituitary	CDK10	0.41	0.22	enet	17	0.15	1.2e-04	4.25	-5.2	2.3e-07	-0.29	0.27	0.14	FALSE
55	GTEx	Skin Sun Exposed Lower leg	CDK10	0.30	0.18	enet	18	0.29	3.0e-24	5.20	-5.1	2.9e-07	-0.15	1.00	0.00	FALSE