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chr19:48,464,978-49,935,001

Best TWAS P=2.67e-09 · Best GWAS P=1.49e-08 conditioned to 0.397

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells Transformed fibroblasts	RASIP1	0.19	0.14	lasso	6	0.20	6.1e-15	5.6	5.7	1.2e-08	0.96	0.01	0.99	FALSE
2	GTEx	Heart Left Ventricle	MAMSTR	0.26	0.18	lasso	6	0.21	3.4e-11	-4.6	5.2	2.5e-07	0.77	0.12	0.88	FALSE
3	GTEx	Skin Not Sun Exposed Suprapubic	NTN5	0.19	0.07	lasso	5	0.08	2.5e-05	5.3	5.6	2.6e-08	0.91	0.02	0.98	FALSE
4	GTEx	Skin Sun Exposed Lower leg	NTN5	0.11	0.09	enet	18	0.05	6.2e-05	5.6	5.3	1.4e-07	0.91	0.01	0.99	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	FUT2	0.03	0.05	blup	54	0.05	1.9e-10	5.6	-5.5	3.0e-08	-0.88	0.01	0.99	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	RASIP1	0.02	0.02	blup	56	0.03	3.8e-07	5.6	5.4	8.6e-08	0.89	0.02	0.98	FALSE
7	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FUT2	0.10	0.02	blup	55	0.06	6.8e-04	5.4	-5.4	7.9e-08	-0.90	0.02	0.98	FALSE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	FUT2	0.18	0.22	enet	12	0.18	6.8e-11	5.3	-5.7	1.5e-08	-0.96	0.02	0.98	FALSE
9	The Cancer Genome Atlas	Esophageal Carcinoma	FUT2	0.33	0.27	lasso	3	0.24	3.9e-08	-5.4	-5.5	3.1e-08	-0.87	0.02	0.98	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FUT2	0.11	0.22	blup	52	0.22	6.3e-24	5.6	-5.2	1.7e-07	-0.92	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FUT2	0.10	0.01	blup	51	0.05	9.8e-04	5.3	-5.3	1.1e-07	-0.86	0.02	0.88	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	NTN5	0.05	0.04	lasso	2	0.02	6.7e-04	5.6	5.6	2.0e-08	0.92	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	FUT2	0.09	0.12	blup	52	0.12	4.2e-14	5.4	-5.4	5.4e-08	-0.92	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FUT2	0.05	0.08	lasso	2	0.08	6.7e-09	5.3	-5.4	6.0e-08	-0.95	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FUT2	0.06	0.00	blup	53	0.05	3.5e-04	5.0	-5.3	1.1e-07	-0.88	0.02	0.83	FALSE
16	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FUT2	0.08	0.12	lasso	4	0.11	2.5e-05	5.6	-5.6	1.8e-08	-1.00	0.01	0.98	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	FUT2	0.05	0.06	blup	52	0.06	8.6e-07	5.6	-5.2	1.8e-07	-0.93	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Rectum Adenocarcinoma	FUT2	0.26	0.28	lasso	10	0.22	5.2e-06	5.6	-5.7	1.3e-08	-0.91	0.01	0.98	FALSE
19	The Cancer Genome Atlas	Stomach Adenocarcinoma	FUT2	0.14	0.16	lasso	8	0.14	4.9e-10	5.6	-5.7	1.3e-08	-0.99	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	FUT2	0.06	0.04	blup	54	0.06	1.1e-06	-5.4	-5.5	3.6e-08	-0.87	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	NTN5	0.11	0.07	blup	43	0.09	2.6e-09	5.4	6.0	2.7e-09	0.89	0.02	0.98	TRUE