Best TWAS P=4.52e-09 · Best GWAS P=1.76e-08 conditioned to 0.00414
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | 5.0 | -5.8 | 6.4e-09 | -0.69 | 0.06 | 0.72 | FALSE |
| 2 | GTEx | Spleen | DCAF16 | 0.35 | 0.02 | lasso | 5 | 0.11 | 8.5e-04 | -4.0 | -5.1 | 2.7e-07 | -0.66 | 0.06 | 0.52 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | -4.3 | -5.9 | 4.5e-09 | -0.55 | 0.05 | 0.85 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | -4.2 | -5.3 | 9.4e-08 | -0.55 | 0.17 | 0.67 | FALSE |