Best TWAS P=2.92e-09 · Best GWAS P=2.77e-12 conditioned to 2.45e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TBC1D19 | 0.14 | 0.05 | lasso | 4 | 0.06 | 5.4e-05 | -5.9 | 5.9 | 2.9e-09 | 0.57 | 0.76 | 0.21 | TRUE |
| 2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | TBC1D19 | 0.56 | 0.18 | blup | 24 | 0.17 | 7.0e-05 | 6.9 | -5.3 | 1.3e-07 | -0.81 | 0.00 | 0.88 | TRUE |