[Hub]/) : Traits : Hypertension (Self-reported) : ← →

chr6:78,880,271-80,486,611

Best TWAS P=1.34e-08 · Best GWAS P=1.62e-08 conditioned to 0.177

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland IRAK1BP1 0.33 0.40 enet 31 0.40 1.5e-15 5.6 5.3 1.3e-07 0.95 0.03 0.97 FALSE
2 GTEx Artery Aorta IRAK1BP1 0.17 0.15 lasso 1 0.11 1.6e-06 5.6 5.5 2.8e-08 0.98 0.03 0.97 FALSE
3 GTEx Artery Tibial IRAK1BP1 0.11 0.15 lasso 4 0.16 1.4e-12 5.6 5.3 1.0e-07 0.96 0.03 0.97 FALSE
4 GTEx Brain Cerebellar Hemisphere IRAK1BP1 0.21 0.13 enet 26 0.12 4.4e-04 -3.7 5.2 2.4e-07 0.84 0.04 0.94 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia IRAK1BP1 0.11 0.08 lasso 10 0.07 6.0e-03 5.4 -5.6 2.4e-08 -0.96 0.04 0.86 FALSE
6 GTEx Colon Sigmoid IRAK1BP1 0.19 0.20 lasso 2 0.17 1.0e-06 5.6 5.5 3.2e-08 0.98 0.03 0.96 FALSE
7 GTEx Esophagus Gastroesophageal Junction IRAK1BP1 0.18 0.18 enet 34 0.18 4.7e-07 5.5 5.1 3.0e-07 0.95 0.04 0.96 FALSE
8 GTEx Esophagus Muscularis IRAK1BP1 0.17 0.22 lasso 4 0.22 1.6e-13 5.6 5.4 7.5e-08 0.96 0.03 0.97 FALSE
9 GTEx Esophagus Muscularis PHIP 0.08 0.04 enet 15 0.02 3.6e-02 5.6 5.7 1.3e-08 0.88 0.03 0.93 TRUE
10 GTEx Heart Atrial Appendage IRAK1BP1 0.15 0.14 lasso 2 0.12 4.6e-06 5.5 5.2 2.5e-07 0.97 0.03 0.96 FALSE
11 GTEx Heart Left Ventricle IRAK1BP1 0.17 0.20 lasso 5 0.20 8.7e-11 5.5 5.5 4.0e-08 0.98 0.03 0.97 FALSE
12 GTEx Lung IRAK1BP1 0.14 0.18 lasso 5 0.17 3.9e-13 5.5 5.3 1.4e-07 0.97 0.04 0.96 FALSE
13 GTEx Muscle Skeletal IRAK1BP1 0.10 0.11 lasso 2 0.10 1.3e-09 5.6 5.6 2.2e-08 0.98 0.03 0.97 FALSE
14 GTEx Ovary IRAK1BP1 0.13 0.15 lasso 2 0.06 1.2e-02 5.5 5.5 4.1e-08 0.98 0.04 0.90 FALSE
15 GTEx Testis IRAK1BP1 0.39 0.56 lasso 11 0.58 7.7e-31 5.5 5.5 3.5e-08 0.98 0.03 0.97 FALSE
16 GTEx Thyroid IRAK1BP1 0.09 0.12 lasso 9 0.11 5.2e-09 5.5 5.5 4.4e-08 0.97 0.03 0.97 FALSE